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市場調查報告書
商品編碼
1871069
生物製藥研發市場-全球及區域分析:依方法、生產類型、類型及地區分類-分析與預測(2025-2035)Biologics Drug Discovery Market - A Global and Regional Analysis: Focus on Method, Manufacturing Type, Type, and Region - Analysis and Forecast, 2025-2035 |
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生物製藥研發市場簡介
2024年全球生物製藥研發市場規模為213.4億美元,預計到2035年將顯著成長至630.7億美元,2025年至2035年的複合年成長率將達到10.38%。
| 關鍵市場統計數據 | |
|---|---|
| 預測期 | 2025-2035 |
| 截至2025年的估值 | 234.9億美元 |
| 2035 年預測 | 630.7億美元 |
| 複合年成長率 | 10.38% |
生物製藥研發市場正經歷穩定成長,這主要得益於慢性病和罕見疾病病例的增加、對精準標標靶治療的需求不斷成長以及治療策略向更有效的作用機制導向型治療方法的轉變。單株抗體、重組蛋白和新一代療法等生物製劑因其優於傳統小分子化合物的選擇性和治療效果而備受關注。政府支持的研發資金、公私合營以及有利的法規結構等扶持措施,進一步加速了創新,並擴大了生物製劑在腫瘤學、免疫學和神經病學等治療領域的應用。
快速的技術進步也正在改變生物製藥研發的格局,人工智慧輔助標靶辨識、高通量篩檢、單細胞分析和抗體工程等技術提高了早期研發的效率和成功率。儘管取得了這些進展,但高昂的研發成本、複雜的生產流程以及研究基礎設施和人才的區域差異等挑戰仍然是規模化生產的重要障礙。然而,持續的全球投資、不斷擴展的外包模式以及對個人化醫療日益成長的需求,預計將在未來十年內將生物製藥研發打造成為下一代治療創新的基石。
市場介紹
在藥物發現平台和策略聯盟的持續創新驅動下,生物製藥研發市場正經歷重大變革。各公司積極採用高通量篩檢、人工智慧驅動的藥物發現平台和先進的抗體庫等尖端技術,以提高治療藥物研發的速度和準確性。 Alloy Therapeutics 的 mAbForge 高通量篩檢服務、百奧賽圖製藥(北京)有限公司的 RenBiologics 抗體平台以及 Evotec SE 的 J.CHO 超表達系統等知名產品的推出,體現了業界對提高生物製劑研發效率和擴充性的重視。隨著生物製藥在滿足腫瘤學、免疫學和罕見疾病領域未被滿足的臨床需求方面的重要性日益凸顯,這些創新有望重塑藥物研發格局,並將生物製藥定位為下一代治療藥物研發的基石。
對產業的影響
在精準標靶治療需求不斷成長以及個人化醫療日益受到重視的推動下,全球生物製藥研發市場正經歷著深刻的變革時期。 Alloy Therapeutics、Charles River Laboratories International、Regeneron Pharmaceuticals 和 WuXi Biologics (Cayman) Inc. 等主要企業在推動生物製藥研發技術方面發揮著核心作用,支持著超越傳統療法的新型治療方法的開發。這些創新在腫瘤學、免疫學和罕見疾病等領域至關重要,能夠實現更有效率、更具針對性的藥物研發,並改善治療效果。透過提高候選藥物辨識的速度和準確性、降低研發成本以及促進全球合作,生物製藥研發有助於建立更有效率、更精簡的治療方案開發流程。生物製劑生物製藥研發與全球精準醫療的轉型相契合,進一步增強了其市場影響力,使其成為下一代治療進步的基石。
市場區隔:
類別 1:依方法
先導化合物的發現/檢驗推動了生物製藥發現市場(按方法分類)
依方法論分類,全球生物製藥研發市場將以先導化合物發現/檢驗主導,預計到2024年將佔28.8%的市場佔有率。該領域在生物製藥開發的早期階段至關重要,因為識別潛在的候選藥物(例如抗體療法)對於治療計畫的成功至關重要。目前應用最廣泛的先導化合物發現/檢驗方法包括噬菌體展示篩檢和融合瘤篩檢,這兩種方法對於產生和檢驗高親和性抗體都至關重要。噬菌體展示技術能夠快速篩檢大型抗體庫以識別特定的候選藥物,而融合瘤篩檢仍是單株抗體生產的基礎。隨著精準醫療需求的不斷成長,這些方法對於發現新的生物製藥至關重要,尤其是在癌症和自體免疫疾病等複雜疾病的治療方面。先進技術的日益普及反映了它們在加速生物製藥藥物研發進程和推動市場持續成長方面的重要作用。
細分2:依生產類型
內部生產是生物製藥研發市場的主要驅動力(按生產類型分類)。
按生產類型分類,內部生產在生物製藥研發市場中佔據主導地位,預計到2024年將佔65.3%的市場佔有率。由於在品管、智慧財產權保護和成本管理方面具有優勢,內部生產仍然是首選方法。然而,隨著越來越多的公司尋求降低營運成本、提高擴充性並獲取專業知識,預計從2025年到2035年,外包生產市場將以11.2%的複合年成長率成長。外包使公司能夠利用合約生產組織(CMO)提供的契約製造技術,例如高通量篩檢和大規模生物製藥生產,而無需大量資本投資。隨著中小型生物技術和製藥公司越來越依賴外部合作夥伴進行生物製藥(包括單株抗體、重組蛋白以及細胞和基因療法)的發現、開發和生產,這種轉變尤其明顯。生物製藥需求的不斷成長,以及生產流程對靈活性和效率的更高要求,預計將推動外包產業的持續成長,而外包產業有望成為生物製藥研發市場擴張的重要因素。
細分3:按類型
其他推動生物製藥生物製藥(按類型分類)
按類型分類,全球生物製藥研發市場將由其他生物製藥細分市場主導,預計到2024年將佔據43.8%的市場佔有率。該細分市場的主導地位歸功於對創新治療方法和治療策略的日益重視,例如個人化醫療、免疫療法和先進疫苗的研發。疫苗需求的激增,尤其是在全球健康危機之後,加速了疫苗生產和研發的步伐。同樣,旨在解決以往難以治癒的遺傳疾病的細胞和基因療法的快速發展,也引起了公共和私營部門的廣泛關注。此外,對包括幹細胞和基因編輯技術在內的細胞療法研發投入的不斷增加,預計將推動該細分市場的持續成長。此類別治療方法的多樣性,加上慢性病和遺傳病患疾病率的上升,使得其他生物製藥細分市場成為整個生物製藥市場的關鍵驅動力。
細分 4:按地區
預計亞太地區將在生物製藥研發市場中實現最高的區域成長率。
預計2025年至2035年預測期內,亞太地區生物製藥研發市場將以11.9%的顯著速度成長。這一快速成長主要受以下幾個關鍵因素驅動:生物技術研發投入的增加、醫療基礎設施的不斷完善以及對個人化醫療日益成長的關注。亞太地區醫療衛生體系多元化且發展迅速,生物製劑領域正取得顯著進展。各國政府和私人機構,特別是中國、日本、印度和韓國等國家,正大力投資生物製藥研發。該地區人口眾多且老化嚴重,加上癌症、糖尿病和自體免疫疾病等慢性病負擔日益加重,迫切需要創新型生物療法。此外,CRISPR和基因編輯等尖端技術的日益普及,以及細胞和基因療法的進步,預計將進一步鞏固該地區在生物製藥研發領域的領先地位。亞太市場也受益於人們對生物相似藥日益成長的關注,因為生物相似藥是昂貴的生物療法的經濟有效的替代品,這使得全部區域更廣泛的患者群體更容易獲得這些治療方法。
生物製藥研發市場的最新趨勢
需求——促進因素、挑戰與機遇
市場促進因素
慢性病和罕見疾病病例增加推動生物製劑需求—對慢性病和罕見疾病創新治療方法的需求日益成長,推動了創新生物製劑的需求及其研發。癌症、自體免疫疾病和心血管疾病等慢性病持續為全球醫療保健系統帶來挑戰。能夠針對特定分子路徑的生物製劑為這些複雜疾病提供了有效的解決方案。此外,罕見疾病的盛行率不斷上升,而這些疾病往往缺乏有效的治療方法,這進一步凸顯了生物製藥在滿足未被滿足的醫療需求方面的重要性。單株抗體、重組蛋白、基因療法和酵素替代療法等治療方法在治療這些疾病方面發揮主導作用。隨著全球醫療保健格局的演變和對先進標靶治療方法需求的增加,新型生物製藥的發現有望在塑造醫療保健的未來方面發揮關鍵作用。
市場挑戰
高昂的研發和生產成本-生物製藥的發現、開發和生產高成本,對市場成長構成重大挑戰。生物製藥,尤其是處於研發或後期開發階段的生物製劑,需要在研究、生產和品管方面投入大量資金。這些流程複雜且資源密集,通常涉及最尖端科技、專用設施和嚴格的監管要求。因此,生物製藥往往比傳統小分子藥物更昂貴,限制了其可近性,尤其是在資源有限或對成本敏感的醫療環境中。此外,生物療法的高昂價格,加上持續研發的需求,給醫療系統和患者帶來了經濟壓力。這些經濟障礙限制了服務不足地區和經濟困難人口獲得生物製藥的機會。克服這些挑戰對於推進生物製藥研發、擴大生物療法的覆蓋範圍以及確保其在各種醫療環境中得到更廣泛的應用至關重要。
市場機遇
人工智慧在生物製藥研發中的應用-將人工智慧(AI)融入生物製藥藥物研發流程,可望大幅提升生物療法的研發速度、效率和成本效益,從而帶來巨大的發展機會。包括機器學習和深度學習在內的人工智慧技術,能夠更精準地預測分子交互作用,最佳化藥物設計,並簡化新型生物製藥。北美和歐洲等專注於創新和先進醫療技術的地區,在將人工智慧融入生物製藥研發方面取得了顯著進展。此外,生物製藥公司與人工智慧技術供應商之間的合作也不斷加強,進一步提升了生物製藥藥物研發平台的能力。
全球生物製藥研發市場已根據技術、生產類型、類型、地區等各種類別進行了詳細細分。這有助於讀者清楚了解哪個細分市場佔據最大佔有率,以及未來幾年該細分市場預計將在哪些方面成長。
夥伴關係、聯盟和業務擴張是主要發展趨勢,約佔 2022 年 1 月至 2025 年 9 月全球生物製藥發現市場所有趨勢的 74%。
競爭策略:全球生物製藥研發市場由眾多擁有豐富產品系列的成熟企業所組成。本研究分析介紹的全球生物製藥研發市場主要企業包括提供生物製藥研發平台、產品和服務的知名公司。
主要市場參與企業及競爭摘要
目標公司的選擇依據是公司概況、產品系列和市場滲透率的分析所收集的資訊。
該市場的主要企業包括:
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Introduction of the Biologics Drug Discovery Market
The global biologics drug discovery market, initially valued at $21.34 billion in 2024, is projected to witness substantial growth, surging to $63.07 billion by 2035, marking a remarkable compound annual growth rate (CAGR) of 10.38% over the period from 2025 to 2035.
| KEY MARKET STATISTICS | |
|---|---|
| Forecast Period | 2025 - 2035 |
| 2025 Evaluation | $23.49 Billion |
| 2035 Forecast | $63.07 Billion |
| CAGR | 10.38% |
The biologics drug discovery market has been witnessing steady growth, driven by the rising prevalence of chronic and rare diseases, increasing demand for precision-targeted therapies, and the shift toward more effective mechanism-based treatments. Biologics such as monoclonal antibodies, recombinant proteins, and next-generation therapies are gaining traction due to their ability to deliver higher selectivity and therapeutic efficacy compared to traditional small molecules. Supportive initiatives, including government-backed R&D funding, public-private collaborations, and favorable regulatory frameworks, are further accelerating innovation and expanding adoption across therapeutic areas such as oncology, immunology, and neurology.
Rapid technological advances are also reshaping the biologics drug discovery landscape, with AI-driven target identification, high-throughput screening, single-cell analysis, and antibody engineering enhancing efficiency and success rates in early-stage development. Despite these tailwinds, challenges such as high development costs, complex manufacturing processes, and regional disparities in research infrastructure and talent remain significant barriers to scale. Nevertheless, continued global investment, expanding outsourcing models, and growing demand for personalized medicine are expected to establish biologics drug discovery as a cornerstone of next-generation therapeutic innovation over the coming decade.
Market Introduction
The biologics drug discovery market has been undergoing a significant transformation, driven by continuous innovation in discovery platforms and strategic partnerships. Companies are increasingly adopting cutting-edge technologies such as high-throughput screening, AI-driven discovery platforms, and advanced antibody libraries to enhance the speed and precision of therapeutic development. Notable product launches, including Alloy Therapeutics, Inc.'s mAbForge high-throughput screening service, Biocytogen Pharmaceuticals (Beijing) Co., Ltd.'s RenBiologics antibody platform, and Evotec SE's J.CHO High Expression System for continuous antibody manufacturing, reflect the industry's focus on improving efficiency and scalability in biologics development. As biologics continue to gain prominence in addressing unmet clinical needs in oncology, immunology, and rare diseases, these innovations are poised to redefine the landscape of drug discovery, positioning biologics as a cornerstone of next-generation therapeutic development.
Industrial Impact
The global biologics drug discovery market has been experiencing a significant shift, driven by the increasing demand for precision-targeted therapies and the growing focus on personalized medicine. Key players such as Alloy Therapeutics, Inc., Charles River Laboratories International, Inc., Regeneron Pharmaceuticals, Inc., and WuXi Biologics (Cayman) Inc. have been playing a central role in advancing biologics discovery technologies, supporting the development of novel therapies beyond traditional approaches. These innovations are crucial in areas such as oncology, immunology, and rare diseases, enabling more efficient and targeted drug development with improved therapeutic outcomes. By enhancing the speed and precision of candidate identification, reducing development costs, and facilitating global partnerships, biologics drug discovery is contributing to a more effective and streamlined therapeutic development process. The market's impact is further amplified by its alignment with the global shift toward precision medicine, positioning biologics as a cornerstone of next-generation therapeutic advancements.
Market Segmentation:
Segmentation 1: By Method
Hit Generation/Validation to Dominate the Biologics Drug Discovery Market (by Method)
Based on the method, the global biologics drug discovery market was led by hit generation/validation, which held a 28.8% share in 2024. This segment is essential in the early stages of biologics development, where identifying potential drug candidates, such as antibody therapeutics, is critical for the success of therapeutic programs. Among the most widely adopted methods in hit generation/validation are phage display screening and hybridoma screening, both of which are pivotal in generating and validating high-affinity antibodies. Phage display allows for the rapid screening of large antibody libraries to identify specific candidates, while hybridoma screening continues to be a cornerstone for monoclonal antibody production. As the demand for precision medicine grows, these methods are crucial in discovering new biologics, particularly for complex diseases such as cancer and autoimmune disorders. The growing adoption of advanced technologies reflects their vital role in accelerating the biologics drug discovery process and positioning the market for sustained growth.
Segmentation 2: By Manufacturing Type
In-house Manufacturing to Dominate the Biologics Drug Discovery Market (by Manufacturing Type)
Based on manufacturing type, the biologics drug discovery market was led by the in-house manufacturing segment, which held a 65.3% share in 2024. In-house production remains the preferred approach due to its control over quality, intellectual property, and cost management. However, the outsourced manufacturing segment is growing at a higher annualized growth rate (CAGR) of 11.2% from 2025 to 2035, as more companies seek to reduce operational costs, increase scalability, and access specialized expertise. Outsourcing enables companies to leverage contract manufacturing organizations (CMOs) for advanced technologies, such as high-throughput screening and large-scale biologics production, without the need for heavy capital investment. This shift is particularly evident as smaller biotech firms and pharmaceutical companies increasingly rely on external partners for the discovery, development, and manufacturing of biologics, including monoclonal antibodies, recombinant proteins, and cell and gene therapies. The rising demand for biologics, coupled with the increased need for flexibility and efficiency in the manufacturing process, is expected to drive continued growth in the outsourcing sector, making it an essential component of the biologics drug discovery market's expansion.
Segmentation 3: By Type
Other Biologics to Dominate the Biologics Drug Discovery Market (by Type)
Based on type, the global biologics drug discovery market was led by the other biologics segment, which held a 43.8% share in 2024. This segment's dominance can be attributed to the growing emphasis on innovative treatments and therapeutic strategies, such as personalized medicine, immunotherapies, and advanced vaccine development. The surge in demand for vaccines, particularly in the wake of global health crises, has accelerated the focus on vaccine production and research. Similarly, the rapid advancement of cell and gene therapies, which aim to address previously untreatable genetic disorders, has garnered substantial attention from both public and private sectors. Furthermore, the increased investment in the research and development of cell-based therapies, including stem cells and gene-editing technologies, is expected to drive the continued growth of this segment. The diversity of treatment approaches within this category, coupled with the rising prevalence of chronic diseases and genetic disorders, positions the other biologics segment as a key driver in the overall biologics market.
Segmentation 4: By Region
Asia-Pacific to Witness the Highest Growth in the Biologics Drug Discovery Market (by Region)
The biologics drug discovery market in the Asia-Pacific region is expected to witness a significant growth rate of 11.9% during the forecast period 2025-2035. This rapid expansion is driven by several key factors, including the increasing investment in biotechnology research, enhanced healthcare infrastructure, and a growing emphasis on personalized medicine. Asia-Pacific, with its diverse and rapidly evolving healthcare landscape, is witnessing significant advancements in biologics, particularly in countries including China, Japan, India, and South Korea, where governments and private organizations are heavily investing in biopharmaceutical research and development. The region's large and aging population, coupled with a rising burden of chronic diseases such as cancer, diabetes, and autoimmune disorders, has created a pressing need for innovative biologic therapies. Furthermore, the increasing adoption of cutting-edge technologies such as CRISPR and gene editing, alongside advancements in cell and gene therapies, is expected to fuel the region's dominance in biologics drug discovery. The Asia-Pacific market is also benefiting from the growing focus on biosimilars, which offer a cost-effective alternative to expensive biologic therapies, making them increasingly accessible to a wider patient base across the region.
Recent Developments in the Biologics Drug Discovery Market
Demand - Drivers, Challenges, and Opportunities
Market Drivers
Rising Prevalence of Chronic and Rare Diseases Driving Biologics Demand: The growing need for innovative treatments in chronic and rare diseases is fueling the demand for innovative biologics and their discovery. Chronic conditions such as cancer, autoimmune disorders, and cardiovascular diseases continue to challenge healthcare systems worldwide. Biologics, with their ability to target specific molecular pathways, offer effective solutions for these complex diseases. Additionally, the increasing prevalence of rare diseases, which often lack viable treatments, further emphasizes the importance of biologics in addressing unmet medical needs. Therapies such as monoclonal antibodies, recombinant proteins, gene therapies, and enzyme replacement therapies are leading the way in treating these conditions. As the global healthcare landscape evolves and the need for advanced, targeted therapies rises, novel biologics drug discovery is anticipated to play a prominent role in shaping the future of medicine.
Market Challenges
High Development and Manufacturing Costs: The high costs associated with the drug discovery, development, and manufacturing of biologics present a significant challenge to market growth. Biologics, particularly those in the R&D phase or advanced stages of development, require substantial investment in research, production, and quality control. These processes are complex and resource-intensive, often involving cutting-edge technologies, specialized facilities, and stringent regulatory requirements. As a result, biologics tend to be more expensive than traditional small-molecule drugs, limiting their accessibility, particularly in resource-constrained or cost-sensitive healthcare environments. Additionally, the high price of biologic therapies, coupled with the need for ongoing research and development, places a strain on healthcare systems and patient affordability. These financial barriers limit access to biologics in underserved regions and among economically disadvantaged populations. Overcoming these challenges will be essential for advancing biologics drug discovery, expanding the reach of biologic treatments, and ensuring their broader adoption across diverse healthcare settings.
Market Opportunities
AI Integration in Biologics Drug Discovery: The integration of artificial intelligence (AI) into biologics drug discovery presents a significant growth opportunity, driven by the potential for faster, more efficient, and cost-effective development of biologic therapies. AI technologies, including machine learning and deep learning, are enabling more accurate prediction of molecular interactions, optimizing drug design, and streamlining the discovery of novel biologic candidates. As AI continues to evolve, its ability to analyze vast datasets, such as genetic information, clinical trial data, and protein structures, has the potential to accelerate the identification of high-potential drug targets and improve the precision of biologics development. In regions including North America and Europe, where there is a strong focus on innovation and advanced healthcare technologies, AI integration in biologics drug discovery is gaining traction. Additionally, collaborations between biopharma companies and AI technology providers are increasing, further enhancing the capabilities of biologics drug discovery platforms.
How can this report add value to an organization?
Product/Innovation Strategy: The global biologics drug discovery market has been extensively segmented based on various categories, such as method, manufacturing type, type, and region. This can help readers get a clear overview of which segments account for the largest share and which ones are well-positioned to grow in the coming years.
Growth/Marketing Strategy: Partnerships, alliances, and business expansions have accounted for the majority of key developments, comprising nearly 74% of the total developments in the global biologics drug discovery market between January 2022 and September 2025.
Competitive Strategy: The global biologics drug discovery market has numerous established players with product portfolios. Key players in the global biologics drug discovery market, analyzed and profiled in the study, include established players offering platforms, products, and services for biologics drug discovery.
Methodology
Key Considerations and Assumptions in Market Engineering and Validation
Primary Research
The primary sources involve industry experts in biologics drug discovery, including the market players offering products and services. Resources such as CEOs, vice presidents, marketing directors, and technology and innovation directors have been interviewed to obtain and verify both qualitative and quantitative aspects of this research study.
The key data points taken from the primary sources include:
Secondary Research
Open Sources
The key data points taken from the secondary sources include:
Key Market Players and Competition Synopsis
The companies profiled have been selected based on inputs gathered from an analysis of company coverage, product portfolio, and market penetration.
Some prominent names established in this market are:
Scope and Definition