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市場調查報告書
商品編碼
1820318
鐮狀細胞疾病治療市場報告:規模、佔有率、趨勢及預測(按治療類型、最終用戶和地區),2025 年至 2033 年Sickle Cell Disease Treatment Market Report Size, Share, Trends and Forecast by Treatment Type, End User, and Region, 2025-2033 |
2024 年全球鐮狀細胞疾病治療市場規模為 40.3 億美元。預計到 2033 年,市場規模將達到 130.6 億美元,2025-2033 年期間的複合年成長率為 13.26%。北美目前佔據市場主導地位,2024 年市佔率約為 38.7%。全球鐮狀細胞病患疾病率上升,新生兒篩檢計畫不斷擴大和診斷能力不斷提高,推動了市場發展。此外,研發投入不斷增加,以及基因和細胞療法的進步,正在加速創新治療方案的普及。此外,政府的支持性政策、醫療資金的增加和各項措施也是擴大鐮狀細胞疾病治療市場佔有率的重要因素。
該市場主要受到發展中地區日益普及的先進醫療基礎設施以及用於遠端監控和患者管理的數位醫療工具整合的影響。例如,加州大學聖地牙哥分校開發了一個基於自動化電子健康記錄的登記系統,用於識別其整個醫療系統中的鐮狀細胞疾病 (SCD) 患者,截至 2024 年 7 月,陽性預測值達到 92.6%。該登記系統已識別出 31 名確診的 SCD 患者,並啟動了有針對性的推廣活動以改善醫療服務可近性。除了患者識別之外,此登記系統還用於監測臨床品質指標、追蹤再入院情況和支持護理協調。此外,公共衛生組織和私人實體之間日益增多的合作正在改善獲得專門治療的機會。此外,在高盛行率地區不斷擴大的臨床試驗網路正在加速開發針對特定區域的治療方案。同樣,對個人化醫療的日益重視也鼓勵使用基因圖譜來指導治療選擇。
美國高度重視健康公平計劃,旨在改善鐮狀細胞疾病高發生率社區的醫療服務可近性。根據2024年的產業報告,鐮狀細胞疾病在美國已影響超過10萬人。鐮狀細胞疾病治療市場的一個重要趨勢是聯邦政府加強對研究的資助力度,加速了創新療法的進展。此外,擁有多學科專業知識的專業治療中心的存在確保了疾病的全面管理。此外,電子健康記錄的廣泛應用促進了協調一致的護理和持續的監測。學術機構與生物技術公司之間日益增多的合作正在推動治療方法的突破。此外,先進療法的優惠報銷框架也支持了更高的採用率,鞏固了美國在鐮狀細胞疾病創新和醫療服務方面的領導地位。
鐮狀細胞疾病(SCD)患者數量增加
鐮狀細胞疾病的全球盛行率正在穩步上升,這得益於高負擔地區人口的成長、存活率的提高以及新生兒篩檢計畫的擴展,這些計畫在出生時可發現更多病例。例如,到2025年,全球將有超過2,000萬人患有鐮狀細胞疾病,其中超過10萬名患者居住在美國。移民模式也加劇了疾病的地理傳播,導致先前鐮狀細胞疾病不常見的地區對治療的需求增加。此外,醫療保健的進步提高了患者的預期壽命,但這也意味著醫療保健系統必須管理更多患有慢性併發症的患者。此外,不斷成長的患者群體也加劇了對多樣化治療方案的需求,包括治癒性和支持性護理。盛行率的上升促使政府、研究機構和醫療保健提供者加強資源配置,擴大治療基礎設施,並加速創新療法的開發,以滿足不斷成長的患者群體不斷變化的需求。
可支配所得的增加和個人意識的增強
可支配收入的增加,尤其是在新興經濟體,使更多患者能夠及時獲得鐮狀細胞疾病 (SCD) 的先進治療。這反過來又支持了鐮狀細胞疾病治療市場的成長。根據行業報告,在美國,2025 年 5 月的可支配個人收入 (DPI) 為 224,546 億美元。隨著經濟能力的提高,個人更有可能獲得專業的醫療服務,接受定期診斷檢查,並負擔得起長期治療計劃,包括更高費用的療法,例如疾病修飾藥物或基因介入。政府主導的宣傳活動、計劃團體和教育計畫不斷提高人們對 SCD 的認知,也進一步促進了這一趨勢。公共衛生計劃正在傳播有關早期症狀、預防措施和可用治療方法的資訊,從而實現更早的診斷和更有效的疾病管理。此外,知識的增強也提高了患者的參與度,個人更願意參與臨床試驗並採用新的療法。財政狀況的改善和認知的提高共同顯著擴大了接受治療的患者群體,刺激了現有和創新 SCD 治療的市場需求。
衛生監管機構的快速核准
各國監管機構越來越重視加速核准創新療法的途徑。這一趨勢正在為鐮狀細胞疾病治療市場帶來積極的前景。例如,美國食品藥物管理局 (USFDA) 於 2019 年批准了一種新藥,用於減輕鐮狀細胞疾病成人和兒童患者的疼痛。這項轉變源自於迫切需要解決沉重的疾病負擔和現有治療方案的限制。優先審查、突破性療法認定和孤兒藥資格等機制正應用於有前景的藥物、基因療法和先進的細胞干預措施。這些加速流程縮短了從臨床開發到上市的時間,使患者更快獲得可能改變人生的治療方案。監管機構也正在加強與研發機構的合作,以便在試驗設計、安全方案和生產標準方面提供早期指導,確保合規性,同時維持高安全基準。這種積極主動的方法不僅支持創新,還鼓勵加大研發投入,因為企業可以預期更快的回報並降低開發風險。
The global sickle cell disease treatment market size was valued at USD 4.03 Billion in 2024. The market is expected to reach USD 13.06 Billion by 2033, exhibiting a CAGR of 13.26% during 2025-2033. North America currently dominates the market, holding a significant market share of around 38.7% in 2024. The market is fueled by the rising prevalence of sickle cell disease globally, supported by expanding newborn screening programs and improved diagnostic capabilities. Besides that, growing investments in research and development, alongside advancements in gene and cell therapies, is accelerating the availability of innovative treatment options. In addition to this, supportive government policies, increased healthcare funding, and initiatives are significant factors augmenting the sickle cell disease treatment market share.
The market is majorly influenced by the increasing availability of advanced healthcare infrastructure in developing regions and the integration of digital health tools for remote monitoring and patient management. For instance, the University of California San Diego developed an automated electronic health record-based registry to identify sickle cell disease (SCD) patients across its health system, achieving a 92.6% positive predictive value, as of July 2024. The registry identified 31 confirmed SCD patients, with targeted outreach initiated to improve care access. Beyond patient identification, the registry is being used to monitor clinical quality metrics, track readmissions, and support care coordination. Moreover, rising collaborations between public health organizations and private entities are enhancing access to specialized treatments. Besides that, expanding clinical trial networks in high-prevalence areas are accelerating the development of region-specific therapeutic solutions. Also, growing emphasis on personalized medicine is encouraging the use of genetic profiling to guide treatment selection.
In the United States, there strong focus on health equity initiatives to improve care access for communities disproportionately affected by sickle cell disease. As per industry reports in 2024, SCD has affected over 100,000 individuals in the United States. One of the significant sickle cell disease treatment market trends is the expansion of federal funding for research, which enables accelerated progress in innovative therapies. In addition to this, the presence of specialized treatment centers with multidisciplinary expertise ensures comprehensive disease management. Moreover, widespread adoption of electronic health records is facilitating coordinated care and continuous monitoring. Increasing partnerships between academic institutions and biotechnology firms are fostering breakthroughs in curative approaches. Additionally, favorable reimbursement frameworks for advanced treatments are supporting higher adoption rates, reinforcing the country's leadership in sickle cell disease innovation and care delivery.
Increase in the Number of Individuals Suffering from SCD
The global prevalence of sickle cell disease is steadily increasing, driven by population growth in high-burden regions, improved survival rates, and expanded newborn screening programs that identify more cases at birth. For instance, in 2025, over 20 Million individuals worldwide suffer from the SCD disorder, with over 100,000 of these patients living in the USA. Migration patterns are also contributing to a broader geographic spread of the disease, leading to increased demand for treatment in areas where SCD was previously uncommon. Besides this, advances in medical care have improved life expectancy for patients, but this also means that the healthcare system must manage a larger number of individuals living with chronic complications. Also, the growing patient base intensifies the need for diversified treatment options, including both curative and supportive care approaches. This rising prevalence is prompting governments, research institutions, and healthcare providers to strengthen resources, expand treatment infrastructure, and accelerate the development of innovative therapies to meet the evolving needs of the expanding patient population.
Rising Disposable Incomes and the Growing Awareness among Individuals
Increasing disposable incomes, particularly in emerging economies, are enabling more patients to seek timely and advanced treatment for sickle cell disease (SCD). This, in turn, is supporting the sickle cell disease treatment market growth. As per industry reports, in the United States, disposable personal income (DPI) in May 2025 was USD 22,454.6 Billion. As financial capacity improves, individuals are more likely to access specialized healthcare facilities, undergo regular diagnostic testing, and afford long-term treatment plans, including higher-cost therapies such as disease-modifying drugs or gene-based interventions. This trend is complemented by growing awareness of SCD through government-led campaigns, advocacy groups, and educational programs. Public health initiatives are disseminating information on early symptoms, preventive measures, and available treatments, leading to earlier diagnoses and more effective disease management. Besides, enhanced knowledge has also resulted in greater patient engagement, with individuals more willing to participate in clinical trials and adopt new therapies. Together, improved financial means and heightened awareness are significantly expanding the treated patient pool, stimulating market demand for both existing and innovative SCD treatments.
Fast-track Approvals by Health Regulatory Authorities
Regulatory agencies in various countries are increasingly prioritizing accelerated pathways for the approval of innovative treatments. This trend is creating a positive sickle cell disease treatment market outlook. For instance, the United States Food and Drug Administration (USFDA) approved a new medicine in 2019 to reduce the pain experienced by adults and children with SCD. This shift is driven by the urgent need to address the significant disease burden and the limitations of existing therapeutic options. Mechanisms such as priority review, breakthrough therapy designation, and orphan drug status are being applied to promising drugs, gene therapies, and advanced cell-based interventions. These expedited processes reduce the time between clinical development and market availability, enabling patients to access potentially life-changing treatments sooner. Regulatory bodies are also enhancing collaboration with developers to provide early guidance on trial design, safety protocols, and manufacturing standards, ensuring compliance while maintaining high safety benchmarks. This proactive approach not only supports innovation but also encourages greater investment in research, as companies can anticipate faster returns and reduced development risk.
Blood transfusion leads the market with around 48.9% of market share in 2024. This type of treatment is one of the most widely used and accessible interventions. It helps reduce the proportion of sickled red blood cells, improving oxygen delivery and lowering the risk of severe complications such as stroke and organ damage. Transfusions are particularly important in managing acute episodes and preventing recurrent crises in high-risk patients. They are also used as a long-term preventive measure for children and adults with severe disease manifestations. While effective, regular transfusions require careful monitoring to manage risks like iron overload and transfusion reactions, which has led to the parallel growth of iron chelation therapies. In regions with limited access to advanced treatments, blood transfusion remains a cornerstone of care, reinforcing its continuing relevance in both developed and resource-constrained healthcare systems.
Hospitals lead the market with around 60.8% of market share in 2024. Hospitals are the leading centers for diagnosis, management, and specialized care. They offer holistic services, which range from emergency interventions for pain crises to administration of blood transfusions and monitoring for complications such as stroke or organ damage. Hospitals are also the main locations for specialized interventions such as stem cell transplants and gene therapy, which need sophisticated infrastructure and multidisciplinary capabilities. Additionally, they have specialized hematology departments and laboratories for ongoing monitoring of patients and management of diseases. They also play a role in patient education, counseling, and coordination of long-term care. In most areas, hospitals serve as referral centers, connecting patients with clinical trials and new treatments. Their capacity to provide both acute and preventive care makes them an important end-user segment, with direct effects on treatment accessibility, quality, and patient outcomes within the market.
In 2024, North America accounted for the largest market share of over 38.7% due to its advanced healthcare infrastructure, high disease awareness, and strong research capabilities. The region benefits from established screening programs, early diagnosis, and access to a broad range of treatment options, from supportive care to cutting-edge gene and cell therapies. Significant investment in clinical research and favorable regulatory pathways support the rapid introduction of new therapies, making the region a leader in innovation. Insurance coverage and government-funded healthcare programs improve access for many patients, though disparities persist among underserved populations. The presence of specialized treatment centers and experienced healthcare professionals ensures high-quality care and ongoing monitoring. With continuous advancements and growing adoption of novel treatments, North America remains a critical market, influencing global trends and driving the pace of therapeutic development for sickle cell disease.
United States Sickle Cell Disease Treatment Market Analysis
In 2024, the United States holds a substantial share of around 89.00% of the sickle cell disease treatment share in North America. United States has witnessed increasing sickle cell disease treatment adoption due to the expansion of diagnostic centers across urban and rural areas. For instance, there are 32,257 businesses in the Diagnostic & Medical Laboratories industry in the United States, which has grown at a CAGR of 4.9 % between 2020 and 2025. The presence of advanced diagnostic facilities has improved early detection and monitoring of sickle cell complications, resulting in more timely therapeutic interventions. These diagnostic centers are equipped with modern tools for genetic screening and hemoglobin electrophoresis, which have made diagnosis more efficient and accessible. Moreover, rising awareness among patients and healthcare professionals about early testing is encouraging regular screenings. Insurance coverage for diagnostic procedures has further contributed to increased utilization of sickle cell treatments. Healthcare systems are increasingly integrating these services into primary care networks, ensuring faster referrals and treatment decisions.
Asia-Pacific Sickle Cell Disease Treatment Market Analysis
Asia-Pacific is experiencing rising adoption of sickle cell disease treatment driven by a noticeable surge in anemia cases across both urban and rural populations. According to Ministry of Health and Family Welfare (MoHFW) (April 2025) indicates that 67.1% of children and 59.1% of adolescent girls are anemic. Increasing awareness regarding hereditary blood disorders and rising anemia prevalence have prompted more individuals to seek medical evaluation for underlying hemoglobinopathies. Healthcare providers are responding by incorporating advanced therapeutic protocols aimed at managing sickle cell complications alongside anemia symptoms. Government health programs are also emphasizing screening initiatives that identify anemia cases potentially linked to sickle cell conditions. In rural areas, community outreach programs are facilitating diagnosis and early treatment. This increasing burden of anemia has highlighted the necessity for tailored interventions and disease management strategies.
Europe Sickle Cell Disease Treatment Market Analysis
The market in the Europe is growing due to several factors, including the Rare Diseases Plan implemented in 2017 within the EU, which significantly enhanced the treatment landscape for rare diseases. This initiative, along with the establishment of 24 European Reference Networks (ERNs), including the ERN on Rare Haematological Diseases (ERN-EuroBloodNet), has fostered increased collaboration among healthcare providers, researchers, and patient organizations. This network focuses specifically on rare blood-related conditions like sickle cell disease, promoting the exchange of knowledge, clinical expertise, and resources across European countries. Furthermore, the growing awareness of the disease and its impact on public health is driving initiatives in several European countries. Collaborative efforts between healthcare providers and non-governmental organizations have also led to improvements in early diagnosis and patient management.
Latin America Sickle Cell Disease Treatment Market Analysis
Latin America has observed a notable increase in sickle cell disease treatment adoption due to improvements in healthcare infrastructure. In countries such as Brazil and Mexico, the government and healthcare systems are focusing on raising awareness about the disease and providing essential healthcare services. Available and extrapolated data indicate that sickle cell disease (SCD) affects more than 6,000 newborns annually and between 100,000 and 150,000 individuals across Latin America. Support from international organizations, including the Pan American Health Organization (PAHO), is also helping improve access to therapies and early diagnosis. The increasing availability of clinical trials for new treatments in Latin America is another significant factor fueling market growth in the region. Privatization is also driving innovation and investment in disease-specific care, including sickle cell therapies. As public-private partnerships expand, more individuals are gaining access to advanced medical services, supporting early diagnosis and sustained treatment for sickle cell complications.
Middle East and Africa Sickle Cell Disease Treatment Market Analysis
Middle East and Africa are experiencing rising sickle cell disease treatment adoption as a result of improved healthcare facilities across several regions. For instance, in 2025, the UAE is currently home to over 150 hospitals and has more than 5,000 healthcare facilities. Moreover, investments in new hospitals, clinics, and hematology units have allowed for better disease management and specialized care. Apart from that, expanded access to professional healthcare staff and modern diagnostic tools is accelerating timely treatment. In addition to this, as per industry reports, Africa carries the greatest burden of sickle cell disease (SCD), with prevalence reaching up to 3% of births in certain regions. This high incidence is driving market growth across the continent.
The market is characterized by rapid innovation, with therapies addressing both symptom control and curative potential. Existing options include supportive care, transfusions, and pharmacological agents aimed at reducing complications. Moreover, advancements in genetic and cell-based therapies are intensifying competition, as these approaches aim to correct the root cause of the disease. Market players are differentiating through safety, efficacy, and delivery methods to reduce treatment burden and improve quality of life. In addition to that, regulatory incentives and expanded clinical research pipelines are accelerating product development, though high costs and limited infrastructure in some regions pose adoption challenges. Competition is also influenced by efforts to expand access in underserved populations through targeted healthcare programs. According to the sickle cell disease treatment market forecast, rising disease awareness, improved diagnostic capabilities, and growing investment in advanced therapeutics are expected to drive strong growth over the next decade, with significant opportunities emerging in both established and resource-limited healthcare systems.