Product Code: 978-1-68038-989-0
Hemophilia Market Growth & Trends:
The global hemophilia market size is estimated to reach USD 21.07 billion by 2030, registering a CAGR of 6.91% from 2025 to 2030, according to a new report by Grand View Research, Inc. The approval of gene therapy and monoclonal antibodies for treating hemophilia and the presence of multiple such candidates in the pipeline are major drivers for market growth. In addition, the increasing life expectancy of hemophilia patients due to reduced mortality is another key factor driving market growth.
The development and launch of novel therapies to control hemophilia are propelling the market growth. For instance, in April 2020, FDA approved the genetically engineered product Sevenfact [coagulation factor VIIa (recombinant)-jncw] as a treatment option to control bleeding episodes in adolescents (of age group 12 years and above) and adults. Furthermore, the presence of 2 gene therapy products, BioMarin's Roctavian for hemophilia A, was approved only in Europe, and CSL's Hemgenix (etranacogene dezaparvovec-drib) was approved both in the U.S., and Europe demonstrates an opportunity for expansion in other regions. BioMarin's Roctavian is under review with the U.S. FDA after its previous rejection and has a PDUFA date set for June 30, 2023.
Major players are focused on developing new products and entering into strategic collaborations for enhanced geographic presence. For instance, in April 2022, Novo Nordisk A/S partnered with Canadian Blood Services to enhance its product offering with marketed drugs Esperoct and Zonovate, publicly available for treating type A. Moreover, in February 2023, Sanofi received FDA approval for its drug Altuviiio, a factor VIII replacement therapy for treating hemophilia A.
However, a key restraining factor is the delayed diagnosis of mild to moderate disease in developing countries such as China and India. Another key challenge for the market is the possible access issues for gene therapy due to its high cost and lack of long-term data. For instance, the cost of treatment using Hemgenix (Approved in 2022) is USD 3.5 million per treatment, making it the most expensive treatment in the world.
Hemophilia Market Report Highlights:
- The type A segment held the largest share of the hemophilia market in 2024, owing to the higher prevalence of hemophilia A and the availability of multiple products for its treatment. This segment is also expected to grow at the highest CAGR during the forecast period owing to the approval of gene therapy.
- Based on the distribution channel, the specialty pharmacies segment held the largest market share in 2024, attributable to the specialized nature of the treatment required for the condition
- By therapy, factor replacement therapy held the largest share of the hemophilia market in 2024, as it is the major form of treatment used in both prophylaxis and on-demand treatment.
- North America was the largest revenue-generating region in the hemophilia market in 2024, which can be attributed to the presence of key players, regulatory support, patient awareness, and favorable funding assistance.
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.2. Segment Definitions
- 1.2.1. Type
- 1.2.2. Treatment
- 1.2.3. Therapy
- 1.2.4. Distribution Channel
- 1.2.5. Regional scope
- 1.2.6. Estimates and forecasts timeline
- 1.3. Research Methodology
- 1.4. Information Procurement
- 1.4.1. Purchased database
- 1.4.2. GVR's internal database
- 1.4.3. Secondary sources
- 1.4.4. Primary research
- 1.4.5. Details of primary research
- 1.4.5.1. Data for primary interviews in North America
- 1.4.5.2. Data for primary interviews in Europe
- 1.4.5.3. Data for primary interviews in Asia Pacific
- 1.4.5.4. Data for primary interviews in Latin America
- 1.4.5.5. Data for Primary interviews in MEA
- 1.5. Information or Data Analysis
- 1.5.1. Data analysis models
- 1.6. Market Formulation & Validation
- 1.7. Model Details
- 1.7.1. Commodity flow analysis (Model 1)
- 1.7.2. Approach 1: Commodity flow approach
- 1.7.3. Volume price analysis (Model 2)
- 1.7.4. Approach 2: Volume price analysis
- 1.8. List of Secondary Sources
- 1.9. List of Primary Sources
- 1.10. Objectives
Chapter 2. Executive Summary
- 2.1. Market Outlook
- 2.2. Segment Outlook
- 2.2.1. Type
- 2.2.2. Treatment
- 2.2.3. Therapy
- 2.2.4. Distribution Channel
- 2.2.5. Regional outlook
- 2.3. Competitive Insights
Chapter 3. Hemophilia Market Variables, Trends & Scope
- 3.1. Market Lineage Outlook
- 3.1.1. Parent market outlook
- 3.1.2. Related/ancillary market outlook
- 3.2. Market Dynamics
- 3.2.1. Market driver analysis
- 3.2.2. Market restraint analysis
- 3.3. Hemophilia Market Analysis Tools
- 3.3.1. Industry Analysis - Porter's
- 3.3.1.1. Supplier power
- 3.3.1.2. Buyer power
- 3.3.1.3. Substitution threat
- 3.3.1.4. Threat of new entrant
- 3.3.1.5. Competitive rivalry
- 3.3.2. PESTEL Analysis
- 3.3.2.1. Political landscape
- 3.3.2.2. Technological landscape
- 3.3.2.3. Economic landscape
- 3.4. Pipeline Analysis
- 3.4.1.1. Phase 1
- 3.4.1.2. Phase 2
- 3.4.1.3. Phase 3
Chapter 4. Hemophilia Market: Disease Type Estimates & Trend Analysis
- 4.1. Type Market Share, 2024 & 2030
- 4.2. Segment Dashboard
- 4.3. Global Hemophilia Market by Type Outlook
- 4.4. Market Size & Forecasts and Trend Analyses, 2018 - 2030 for the following
- 4.4.1. Hemophilia A
- 4.4.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 4.4.2. Hemophilia B
- 4.4.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 4.4.3. Others
- 4.4.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
Chapter 5. Hemophilia Market: Treatment Type Estimates & Trend Analysis
- 5.1. Treatment Type Market Share, 2024 & 2030
- 5.2. Segment Dashboard
- 5.3. Global Hemophilia Market by Treatment Type Outlook
- 5.4. Market Size & Forecasts and Trend Analyses, 2018 - 2030 for the following
- 5.4.1. On-demand
- 5.4.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 5.4.2. Cure
- 5.4.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 5.4.3. Prophylaxis
- 5.4.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
Chapter 6. Hemophilia Market: Therapy Estimates & Trend Analysis
- 6.1. Therapy Market Share, 2024 & 2030
- 6.2. Segment Dashboard
- 6.3. Global Hemophilia Market by Therapy Outlook
- 6.4. Market Size & Forecasts and Trend Analyses, 2018 - 2030 for the following
- 6.4.1. Factor Replacement Therapy
- 6.4.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.1.2. Plasma derived Factor Concentrates estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.1.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.1.2.2. Factor VIII
- 6.4.1.2.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.1.2.3. Factor IX
- 6.4.1.2.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.1.3. Recombinant Factor Concentrates
- 6.4.1.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.1.3.1.1. Factor VIII
- 6.4.1.3.1.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.1.3.1.2. Factor VII
- 6.4.1.3.1.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.1.3.1.3. Factor IX
- 6.4.1.3.1.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.2. Desmopressin & Fibrin sealants
- 6.4.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 6.4.3. Gene Therapy & Monoclonal Antibodies
- 6.4.3.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
Chapter 7. Hemophilia Market: Distribution Channel Estimates & Trend Analysis
- 7.1. Distribution Channel Market Share, 2024 & 2030
- 7.2. Segment Dashboard
- 7.3. Global Hemophilia Market by Gender Outlook
- 7.4. Market Size & Forecasts and Trend Analyses, 2018 - 2030 for the following
- 7.4.1. Hospital Pharmacies
- 7.4.1.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
- 7.4.2. Specialty Pharmacies
- 7.4.2.1. Market estimates and forecasts, 2018 - 2030 (USD Million)
Chapter 8. Hemophilia Market: Regional Estimates & Trend Analysis
- 8.1. Regional Market Share Analysis, 2024 & 2030
- 8.2. Regional Market Dashboard
- 8.3. Global Regional Market Snapshot
- 8.4. Market Size, & Forecasts Trend Analysis, 2018 - 2030:
- 8.5. North America
- 8.5.1. U.S.
- 8.5.1.1. Key country dynamics
- 8.5.1.2. Regulatory framework/ reimbursement structure
- 8.5.1.3. Competitive scenario
- 8.5.1.4. U.S. market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.5.2. Canada
- 8.5.2.1. Key country dynamics
- 8.5.2.2. Regulatory framework/ reimbursement structure
- 8.5.2.3. Competitive scenario
- 8.5.2.4. Canada market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.5.3. Mexico
- 8.5.3.1. Key country dynamics
- 8.5.3.2. Regulatory framework/ reimbursement structure
- 8.5.3.3. Competitive scenario
- 8.5.3.4. Mexico market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.6. Europe
- 8.6.1. UK
- 8.6.1.1. Key country dynamics
- 8.6.1.2. Regulatory framework/ reimbursement structure
- 8.6.1.3. Competitive scenario
- 8.6.1.4. UK market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.6.2. Germany
- 8.6.2.1. Key country dynamics
- 8.6.2.2. Regulatory framework/ reimbursement structure
- 8.6.2.3. Competitive scenario
- 8.6.2.4. Germany market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.6.3. France
- 8.6.3.1. Key country dynamics
- 8.6.3.2. Regulatory framework/ reimbursement structure
- 8.6.3.3. Competitive scenario
- 8.6.3.4. France market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.6.4. Italy
- 8.6.4.1. Key country dynamics
- 8.6.4.2. Regulatory framework/ reimbursement structure
- 8.6.4.3. Competitive scenario
- 8.6.4.4. Italy market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.6.5. Spain
- 8.6.5.1. Key country dynamics
- 8.6.5.2. Regulatory framework/ reimbursement structure
- 8.6.5.3. Competitive scenario
- 8.6.5.4. Spain market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.6.6. Norway
- 8.6.6.1. Key country dynamics
- 8.6.6.2. Regulatory framework/ reimbursement structure
- 8.6.6.3. Competitive scenario
- 8.6.6.4. Norway market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.6.7. Sweden
- 8.6.7.1. Key country dynamics
- 8.6.7.2. Regulatory framework/ reimbursement structure
- 8.6.7.3. Competitive scenario
- 8.6.7.4. Sweden market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.6.8. Denmark
- 8.6.8.1. Key country dynamics
- 8.6.8.2. Regulatory framework/ reimbursement structure
- 8.6.8.3. Competitive scenario
- 8.6.8.4. Denmark market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.7. Asia Pacific
- 8.7.1. Japan
- 8.7.1.1. Key country dynamics
- 8.7.1.2. Regulatory framework/ reimbursement structure
- 8.7.1.3. Competitive scenario
- 8.7.1.4. Japan market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.7.2. China
- 8.7.2.1. Key country dynamics
- 8.7.2.2. Regulatory framework/ reimbursement structure
- 8.7.2.3. Competitive scenario
- 8.7.2.4. China market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.7.3. India
- 8.7.3.1. Key country dynamics
- 8.7.3.2. Regulatory framework/ reimbursement structure
- 8.7.3.3. Competitive scenario
- 8.7.3.4. India market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.7.4. Australia
- 8.7.4.1. Key country dynamics
- 8.7.4.2. Regulatory framework/ reimbursement structure
- 8.7.4.3. Competitive scenario
- 8.7.4.4. Australia market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.7.5. South Korea
- 8.7.5.1. Key country dynamics
- 8.7.5.2. Regulatory framework/ reimbursement structure
- 8.7.5.3. Competitive scenario
- 8.7.5.4. South Korea market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.7.6. Thailand
- 8.7.6.1. Key country dynamics
- 8.7.6.2. Regulatory framework/ reimbursement structure
- 8.7.6.3. Competitive scenario
- 8.7.6.4. Thailand market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.8. Latin America
- 8.8.1. Brazil
- 8.8.1.1. Key country dynamics
- 8.8.1.2. Regulatory framework/ reimbursement structure
- 8.8.1.3. Competitive scenario
- 8.8.1.4. Brazil market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.8.2. Argentina
- 8.8.2.1. Key country dynamics
- 8.8.2.2. Regulatory framework/ reimbursement structure
- 8.8.2.3. Competitive scenario
- 8.8.2.4. Argentina market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.9. MEA
- 8.9.1. South Africa
- 8.9.1.1. Key country dynamics
- 8.9.1.2. Regulatory framework/ reimbursement structure
- 8.9.1.3. Competitive scenario
- 8.9.1.4. South Africa market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.9.2. Saudi Arabia
- 8.9.2.1. Key country dynamics
- 8.9.2.2. Regulatory framework/ reimbursement structure
- 8.9.2.3. Competitive scenario
- 8.9.2.4. Saudi Arabia market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.9.3. UAE
- 8.9.3.1. Key country dynamics
- 8.9.3.2. Regulatory framework/ reimbursement structure
- 8.9.3.3. Competitive scenario
- 8.9.3.4. UAE market estimates and forecasts, 2018 - 2030 (USD Million)
- 8.9.4. Kuwait
- 8.9.4.1. Key country dynamics
- 8.9.4.2. Regulatory framework/ reimbursement structure
- 8.9.4.3. Competitive scenario
- 8.9.4.4. Kuwait market estimates and forecasts, 2018 - 2030 (USD Million)
Chapter 9. Competitive Landscape
- 9.1. Recent Developments & Impact Analysis, By Key Market Participants
- 9.2. Company/Competition Categorization
- 9.3. Vendor Landscape
- 9.3.1. List of key distributors and channel partners
- 9.3.2. Key customers
- 9.3.3. Key company market share analysis, 2024
- 9.3.4. Takeda Pharmaceutical Company Limited.
- 9.3.4.1. Company overview
- 9.3.4.2. Financial performance
- 9.3.4.3. Product benchmarking
- 9.3.4.4. Strategic initiatives
- 9.3.5. CSL Behring
- 9.3.5.1. Company overview
- 9.3.5.2. Financial performance
- 9.3.5.3. Product benchmarking
- 9.3.5.4. Strategic initiatives
- 9.3.6. Pfizer Inc.
- 9.3.6.1. Company overview
- 9.3.6.2. Financial performance
- 9.3.6.3. Product benchmarking
- 9.3.6.4. Strategic initiatives
- 9.3.7. Bayer AG
- 9.3.7.1. Company overview
- 9.3.7.2. Financial performance
- 9.3.7.3. Product benchmarking
- 9.3.7.4. Strategic initiatives
- 9.3.8. BioMarin
- 9.3.8.1. Company overview
- 9.3.8.2. Financial performance
- 9.3.8.3. Product benchmarking
- 9.3.8.4. Strategic initiatives
- 9.3.9. Spark Therapeutics, Inc.
- 9.3.9.1. Company overview
- 9.3.9.2. Financial performance
- 9.3.9.3. Product benchmarking
- 9.3.9.4. Strategic initiatives
- 9.3.10. Sanofi
- 9.3.10.1. Company overview
- 9.3.10.2. Financial performance
- 9.3.10.3. Product benchmarking
- 9.3.10.4. Strategic initiatives
- 9.3.11. F. Hoffmann La-Roche Ltd
- 9.3.11.1. Company overview
- 9.3.11.2. Financial performance
- 9.3.11.3. Product benchmarking
- 9.3.11.4. Strategic initiatives
- 9.3.12. Novo Nordisk A/S
- 9.3.12.1. Company overview
- 9.3.12.2. Financial performance
- 9.3.12.3. Product benchmarking
- 9.3.12.4. Strategic initiatives
- 9.3.13. Octapharma AG.
- 9.3.13.1. Company overview
- 9.3.13.2. Financial performance
- 9.3.13.3. Product benchmarking
- 9.3.13.4. Strategic initiatives