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市場調查報告書
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2110462

全球合成生物學市場（2027-2037 年）

The Global Synthetic Biology Market 2027-2037
出版日期: | 出版商: Future Markets, Inc. | 英文 493 Pages, 137 Tables, 68 Figures | 訂單完成後即時交付

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合成生物學將工程原理應用於生命系統，旨在設計和建造自然界中不存在的生物組件、裝置和生物體，或對現有生物體進行改造以滿足特定用途。它與傳統的基因工程在目標和方法上有所不同。基因工程對現有生物體進行有限且有針對性的改造，而合成生物學則將生物體視為一個可程式設計平台，透過「設計、建構、測試和學習」的迭代循環來改造生物體，並充分利用分子生物學、工程學、電腦科學和自動化領域的知識。由此產生的成果也各不相同，不僅能增強生物體的性狀，還能創造出全新的生物體、代謝途徑和生物分子。

該領域涵蓋廣泛的技術基礎。 DNA合成與組裝、基因組工程、代謝工程、蛋白質與酶工程、合成基因組學和電腦輔助設計構成了核心工具集，並由自動化生物鑄造廠、生物感測器、機器人技術以及不斷擴展的異質生物學和細胞株能力提供支援。這些工具被應用於極其廣泛的終端市場，包括製藥和醫療保健、生物基化學品、生質塑膠和生物聚合物、生質燃料、農業、食品和營養補充劑成分、紡織品、包裝、化妝品、表面活性劑、建築材料、生物催化劑和生物修復。

當前時代有三個顯著的結構性變化。首先是融合。合成生物學、工業酵素和白色生物技術過去一直被視為獨立的領域，但如今共用相同的工具集、相同的客戶群體，財務狀況也日益趨於一致。因此，將它們割裂開來是不自然的，更共用的做法是將它們視為單一的工業生物製造市場。

其次，政策已從單純的背景因素提升為主要決定因素。歐盟、美國和亞洲的法律規範和產業戰略如今在很大程度上決定了生產能力的佈局地點和產品優先上市的順序，而生物基含量要求和公共採購優先權等需求側措施的影響可能比核准流程改革更大。

第三，也是商業性最重要的一點，規模化仍然是關鍵限制因素。實驗室和台式規模的實驗結果具有可靠的可重複性。然而，一旦發酵規模擴大到商業規模，氧氣傳輸的限制、散熱的限制、污染風險、原料的差異以及下游回收損失等問題就會顯現出來——這些問題在小規模中並不明顯——而這些問題往往會降低製程的經濟效益。這種差距解釋了為什麼資金雄厚的平台公司在後期資金籌措和商業化之間經常遭遇失敗。

因此，市場呈現兩極化。擁有生產資產、契約製造合作夥伴關係或共用試點設施的公司正在將自身的技術能力轉化為收入。同時，僅擁有技術許可的公司仍受制於生技資金籌措週期。預計產業重組將持續進行。

本報告以2019年的歷史數據為基礎，對2027年至2037年全球合成生物學和生物製造市場進行了全面分析。該報告還評估了影響該行業的技術、商業性和監管因素，並按技術平台、產品類型、應用領域和地區對市場進行了細分。報告涵蓋了合成生物學商業化的以下應用領域：生質燃料、生物基化學品、生物塑膠和生物聚合物、生質塑膠、生物催化劑、食品和營養補充劑成分、永續農業、紡織品、包裝、醫療保健和製藥、化妝品、表面活性劑和清潔劑以及建築材料。

技術分析涵蓋了廣泛的生物製造程序，從分批和連續發酵到無細胞合成、基於生物膜的生產、微流體系統、光生物反應器、膜生物反應器、植物和哺乳動物細胞培養以及生物列印。此外，它還探討了代謝工程、基因和DNA合成、基因合成和組裝、基因組工程、蛋白質和酶工程、合成基因組學、菌株構建和最佳化、智慧生物製程、底盤生物學、仿生技術、永續材料、機器人和自動化、生物資訊學和檢驗工具、異源生物學和擴展基因庫、生物感測器和生物電子、原料以及海洋生物技術。

本報告包括到 2037 年的詳細技術藍圖、SWOT 分析、對行業面臨的挑戰和限制因素的評估、對規模化和試點基礎設施瓶頸的分析（這些瓶頸仍然決定哪些公司能夠實現商業化生產）、歐盟、美國和亞洲的監管和政策趨勢、工業生物技術的價值鏈、合成生物與工業酶和白色生物技術的融合，以及整個產業投資的設計。

本報告包含 137 個表格、68 個圖表和 327 家公司的公司簡介，涵蓋了整個合成生物學價值鏈，從 DNA 合成和生物鑄造平台到發酵製造商、材料公司和終端市場品牌。重點介紹的公司包括：Aanika Biosciences、Aemetis、AEP Polymers、Afyren、AgBiome、AgriSea NZ Seaweed、Agrivida、Ainnocence、AIO、AI Proteins、Algal Bio、Algenol、AlgiKnit、Algiecel、Alpha Biofuels、Allonnia、AllxA、Algenol、Alphayal、Aliim、Alpha Biofuels、Allonnia、Amp Discovery、AMSilk、Amyris、Andes Ag、Ansa Biotechnologies、Antheia、Apeel Sciences、Aralez Bio、Arctic Biomaterials、Ardra Bio、Arkeon、Arsenale Bioyards、Arzeda、Asimov、Atantares、Autolus、VAVA Biochem、Avantium、Aanchem、Axcelon​​ncaxS、Autoft、AITS、Avantium、Aanchem、Axcelon​​nIT、AcBaseium、Ax元素、Axcelium Research） Acid、Benefuel、BioBetter、Bioextrax、Bio Fab NZ。 Biokemik、BIOLO、Biomason、Biomemory、Bioplastech、BioSmart Nano、Biotic Circular Technologies、Biosyntia、Biotecam、Bioweg、bit.bio、Bloom Biorenewables、BluCon Biotech、Blue BioFuels、Bluephaolt、Bon Bioant、Bread Threnewables、BluCon Biotech、Blue BioFuels、Bluephaolt、Bon Bioant、Bitk Th Chemicals、C16 Biosciences、CABIO Biotech、California Cultured、Calysta、Cambrium、Camena Bioscience、Capra Biosciences、Carbios、Cargill、Calyxt、Cascade Biocatalysts、Cass Materials、Catalyxx、Cathy Biotech、CauldFactor Ferpotin、Cemose、C 它Evolution、CinderBio、Circe、CJ Biomaterials、Clean Food Group、Codagenix、Codexis、Colossal Biosciences Colipi、Colorifix、Conagen、Constructive Bio、Cysbio、Danimer Scientific、Debut Biotechnology、Deep Branch Biotechnology、Demetrix、Danimer Scientific、Debut Biotechnology、Deep Branch Biotechnology、Demek、Danimer Scientific、Debut Biotechnology、Deeps Branch Biotechnology、Demek、Danimer Scients、Distechnology、Dencetechnology. Fabriker、DoriNano、DuPont、Earli、Ecovative Design、Eco Fuel Technology、Eden Brew、EggPlant、Eligo Bioscience、Elo Life Systems、Emerging Fuels Technology、Enduro Genetics、EnginZyme、Eni、EnEs Biosciences、Enzymaster、Enzymit、Erebagen、Es。此外，SynBio、Euglena、Eversyn、Evozyne、FabricNano、Fermentalg、Forage Evolution 等公司也名列其中。

目錄

第1章摘要整理

  • 全球合成生物學市場概覽
  • 合成生物學和基因工程的區別
  • 市場規模和成長預測
  • 主要趨勢和促進因素
  • 合成生物學的投資
  • 技術藍圖
  • 技術融合：合成生物學、工業酵素與白色生物技術
  • 監管和政策環境
  • 生物技術的色彩
  • 工業生物技術價值鏈

第2章：引言

  • 什麼是合成生物學？
  • 與傳統製程的比較
  • 目的
  • 優勢
  • 永續性
  • 合成生物學輔助循環經濟

第3章 技術分析

  • 生物製造程序
    • 批量生物製造
    • 連續生物製造
    • 發酵過程
    • 無細胞合成
    • 基於生物膜的生產
    • 微流體系統
    • 輕型生物反應器
    • 膜生物反應器
    • 植物細胞培養
    • 哺乳動物細胞培養
    • 生物列印
  • 用於生物製造的細胞工廠
  • 技術概述
    • 代謝工程
    • 遺傳和DNA合成
    • 基因合成與組裝
    • 基因組工程
    • 蛋白質/酵素工程
    • 合成基因組學
    • 應變建構與最佳化
    • 智慧生物製程
    • 底盤生物
    • 仿生技術
    • 永續材料
    • 機器人與自動化
    • 生物資訊學和計算工具
    • 異質生物學和擴展遺傳字母表
    • 生物感測器和生物電子學
    • 原料
    • 海洋生物技術

第4章 市場分析

  • 市場趨勢和促進因素
  • 產業挑戰與限制因素
  • 生物經濟中的合成生物學
  • SWOT分析
  • 合成生物學市場
    • 生質燃料
    • 生物衍生化學品
    • 生質塑膠和生物聚合物
    • 生物修復
    • 生物催化劑
    • 食品及營養補充品成分
    • 永續農業
    • 紡織品
    • 包裝
    • 醫療和藥品
    • 化妝品
    • 界面活性劑和清潔劑
    • 建材
  • 全球市場收入（2019-2037 年）
    • 透過技術
    • 依產品類型
    • 按市場
    • 按地區
  • 擴大規模和試點基礎設施
  • 天然分子藥物的開發
  • 未來市場展望

第5章：公司簡介（327家公司簡介）

第6章附錄

第7章參考文獻

Synthetic biology applies engineering principles to living systems, designing and constructing biological parts, devices and organisms that do not occur in nature, or redesigning existing ones for defined purposes. It differs from conventional genetic engineering in both ambition and method. Where genetic engineering introduces limited, targeted modifications to an existing organism, synthetic biology treats biology as a programmable platform, engineered through iterative design-build-test-learn cycles that draw on molecular biology, engineering, computer science and automation. The outputs are correspondingly different: not merely enhanced organism traits, but novel organisms, metabolic pathways and biomolecules.

The field spans a broad technology base. DNA synthesis and assembly, genome engineering, metabolic engineering, protein and enzyme engineering, synthetic genomics and computational design form the core toolset, supported by automated biofoundries, biosensors, robotics and expanding capability in xenobiology and cell-free systems. These tools are deployed across an unusually wide range of end markets - pharmaceuticals and healthcare, bio-based chemicals, bioplastics and biopolymers, biofuels, agriculture, food and nutraceutical ingredients, textiles, packaging, cosmetics, surfactants, construction materials, biocatalysis and bioremediation.

Three structural shifts define the current period. The first is convergence. Synthetic biology, industrial enzymes and white biotechnology were historically analysed as separate sectors; they now share the same toolsets, the same customers and increasingly the same balance sheets, making separate segmentation artificial and treating them as one industrial biomanufacturing market more accurate.

The second is the elevation of policy from background condition to primary determinant. Regulatory frameworks and industrial strategy in the European Union, United States and Asia now materially shape where production capacity is built and which products reach market first, with demand-side measures such as bio-based content requirements and public procurement preferences potentially more consequential than approval-pathway reform.

The third, and the most important commercially, is that scale-up remains the binding constraint. Laboratory and bench results reproduce reliably. The transition to commercial fermentation volumes exposes oxygen transfer limits, heat removal constraints, contamination risk, feedstock variability and downstream recovery losses that were invisible at small scale and that routinely destroy process economics. This gap explains the recurring pattern of well-funded platform companies failing between late-stage financing and commercial launch.

The consequence is a bifurcating market. Companies with production assets, contract manufacturing relationships or access to shared pilot infrastructure are converting technical capability into revenue. Those licensing technology alone remain exposed to the biotechnology funding cycle. Consolidation is expected to continue.

This report provides a comprehensive analysis of the global synthetic biology and biomanufacturing market across the 2027-2037 period, with historical context from 2019. It assesses the technical, commercial and regulatory factors shaping the sector, and segments the market by technology platform, product type, application sector and geography. Coverage extends across the applications in which synthetic biology is being commercialised: biofuels, bio-based chemicals, bioplastics and biopolymers, bioremediation, biocatalysis, food and nutraceutical ingredients, sustainable agriculture, textiles, packaging, healthcare and pharmaceuticals, cosmetics, surfactants and detergents, and construction materials.

Technology analysis covers biomanufacturing processes from batch and continuous fermentation through cell-free synthesis, biofilm-based production, microfluidic systems, photobioreactors, membrane bioreactors, plant and mammalian cell culture and bioprinting. It also examines metabolic engineering, gene and DNA synthesis, gene synthesis and assembly, genome engineering, protein and enzyme engineering, synthetic genomics, strain construction and optimisation, smart bioprocessing, chassis organisms, biomimetics, sustainable materials, robotics and automation, bioinformatics and computational tools, xenobiology and expanded genetic alphabets, biosensors and bioelectronics, feedstocks, and marine biotechnology.

The report includes a detailed technology roadmap to 2037, SWOT analysis, assessment of industry challenges and constraints, analysis of the scale-up and pilot infrastructure bottleneck that continues to determine which companies reach commercial production, the regulatory and policy landscape across the European Union, United States and Asia, the industrial biotechnology value chain, the convergence of synthetic biology with industrial enzymes and white biotechnology, and a review of investment activity across the sector.

The report contains 137 tables, 68 figures and profiles of 327 companies spanning the synthetic biology value chain, from DNA synthesis and biofoundry platforms through fermentation producers, materials companies and end-market brands. Companies profiled include Aanika Biosciences, Aemetis, AEP Polymers, Afyren, AgBiome, AgriSea NZ Seaweed, Agrivida, Ainnocence, AIO, AI Proteins, Algal Bio, Algenol, AlgiKnit, Algiecel, Alpha Biofuels, Allonnia, Allozymes, Alt.Leather, Alto Neuroscience, Amano Enzyme, AmphiStar, Amply Discovery, AMSilk, Amyris, Andes Ag, Ansa Biotechnologies, Antheia, Apeel Sciences, Aralez Bio, Arctic Biomaterials, Ardra Bio, Arkeon, Arsenale Bioyards, Arzeda, Asimov, Atantares, Autolus, AVA Biochem, Avantium, Azolla, Axcelon Biopolymers, Basecamp Research, BBCA Biochemical & GALACTIC Lactic Acid, Benefuel, BioBetter, Bioextrax, Bio Fab NZ, Biokemik, BIOLO, Biomason, Biomemory, Bioplastech, BioSmart Nano, Biotic Circular Technologies, Biosyntia, Biotecam, Bioweg, bit.bio, Bloom Biorenewables, BluCon Biotech, Blue BioFuels, Bluepha, Bon Vivant, Bolt Threads, Bosk Bioproducts, Bowil Biotech, Braskem, Brightseed, Bucha Bio, C1 Green Chemicals, C16 Biosciences, CABIO Biotech, California Cultured, Calysta, Cambrium, Camena Bioscience, Capra Biosciences, Carbios, Cargill, Calyxt, Cascade Biocatalysts, Cass Materials, Catalyxx, Cathy Biotech, Cauldron Ferm, Cemvita Factory, ChainCraft, Checkerspot, Chitose Bio Evolution, CinderBio, Circe, CJ Biomaterials, Clean Food Group, Codagenix, Codexis, Colossal Biosciences, Colipi, Colorifix, Conagen, Constructive Bio, Cysbio, Danimer Scientific, Debut Biotechnology, Deep Branch Biotechnology, Demetrix, Dispersa, DMC Biotechnologies, DNA Script, Domsjo Fabriker, DoriNano, DuPont, Earli, Ecovative Design, Eco Fuel Technology, Eden Brew, EggPlant, Eligo Bioscience, Elo Life Systems, Emerging Fuels Technology, Enduro Genetics, EnginZyme, Eni, EnPlusOne Biosciences, Enzymaster, Enzymit, Erebagen, Esphera SynBio, Euglena, Eversyn, Evozyne, FabricNano, Fermentalg, Forage Evolution and more......

Table of Contents

1 EXECUTIVE SUMMARY

  • 1.1 Overview of the global synthetic biology market
  • 1.2 Difference between synthetic biology and genetic engineering
  • 1.3 Market size and growth projections
    • 1.3.1 By Technology
    • 1.3.2 By Product Type
    • 1.3.3 By Market
    • 1.3.4 By Region
  • 1.4 Major trends and drivers
  • 1.5 Investments in synthetic biology
  • 1.6 Technology roadmap
  • 1.7 Technology convergence: synthetic biology, industrial enzymes and white biotechnology
  • 1.8 Regulatory and policy landscape
  • 1.9 Colours of biotechnology
  • 1.10 Industrial biotechnology value chain

2 INTRODUCTION

  • 2.1 What is synthetic biology?
  • 2.2 Comparison with conventional processes
  • 2.3 Applications
  • 2.4 Advantages
  • 2.5 Sustainability
  • 2.6 Synthetic Biology for the Circular Economy

3 TECHNOLOGY ANALYSIS

  • 3.1 Biomanufacturing processes
    • 3.1.1 Batch biomanufacturing
    • 3.1.2 Continuous biomanufacturing
    • 3.1.3 Fermentation Processes
    • 3.1.4 Cell-free synthesis
    • 3.1.5 Biofilm-based production
    • 3.1.6 Microfluidic systems
    • 3.1.7 Photobioreactors
    • 3.1.8 Membrane bioreactors
    • 3.1.9 Plant cell culture
    • 3.1.10 Mammalian cell culture
    • 3.1.11 Bioprinting
  • 3.2 Cell factories for biomanufacturing
  • 3.3 Technology Overview
    • 3.3.1 Metabolic engineering
    • 3.3.2 Gene and DNA synthesis
    • 3.3.3 Gene Synthesis and Assembly
    • 3.3.4 Genome engineering
      • 3.3.4.1 CRISPR
        • 3.3.4.1.1 CRISPR/Cas9-modified biosynthetic pathways
        • 3.3.4.1.2 TALENs
        • 3.3.4.1.3 ZFNs
    • 3.3.5 Protein/Enzyme Engineering
    • 3.3.6 Synthetic genomics
      • 3.3.6.1 Principles of Synthetic Genomics
      • 3.3.6.2 Synthetic Chromosomes and Genomes
    • 3.3.7 Strain construction and optimization
    • 3.3.8 Smart bioprocessing
    • 3.3.9 Chassis organisms
    • 3.3.10 Biomimetics
    • 3.3.11 Sustainable materials
    • 3.3.12 Robotics and automation
      • 3.3.12.1 Robotic cloud laboratories
      • 3.3.12.2 Automating organism design
      • 3.3.12.3 Artificial intelligence and machine learning
    • 3.3.13 Bioinformatics and computational tools
      • 3.3.13.1 Role of Bioinformatics in Synthetic Biology
      • 3.3.13.2 Computational Tools for Design and Analysis
    • 3.3.14 Xenobiology and expanded genetic alphabets
    • 3.3.15 Biosensors and bioelectronics
    • 3.3.16 Feedstocks
      • 3.3.16.1 C1 feedstocks
        • 3.3.16.1.1 Advantages
        • 3.3.16.1.2 Pathways
        • 3.3.16.1.3 Challenges
        • 3.3.16.1.4 Non-methane C1 feedstocks
        • 3.3.16.1.5 Gas fermentation
      • 3.3.16.2 C2 feedstocks
      • 3.3.16.3 Biological conversion of CO2
      • 3.3.16.4 Food processing wastes
      • 3.3.16.5 Lignocellulosic biomass
      • 3.3.16.6 Syngas
      • 3.3.16.7 Glycerol
      • 3.3.16.8 Methane
      • 3.3.16.9 Municipal solid wastes
      • 3.3.16.10 Plastic wastes
      • 3.3.16.11 Plant oils
      • 3.3.16.12 Starch
      • 3.3.16.13 Sugars
      • 3.3.16.14 Used cooking oils
      • 3.3.16.15 Green hydrogen production
      • 3.3.16.16 Blue hydrogen production
    • 3.3.17 Marine biotechnology
      • 3.3.17.1 Cyanobacteria
      • 3.3.17.2 Macroalgae
      • 3.3.17.3 Companies

4 MARKET ANALYSIS

  • 4.1 Market trends and drivers
  • 4.2 Industry challenges and constraints
  • 4.3 Synthetic biology in the bioeconomy
  • 4.4 SWOT analysis
  • 4.5 Synthetic biology markets
    • 4.5.1 Biofuels
      • 4.5.1.1 Solid Biofuels
      • 4.5.1.2 Liquid Biofuels
      • 4.5.1.3 Gaseous Biofuels
      • 4.5.1.4 Conventional Biofuels
      • 4.5.1.5 Advanced Biofuels
      • 4.5.1.6 Feedstocks
        • 4.5.1.6.1 First-generation (1-G)
        • 4.5.1.6.2 Second-generation (2-G)
          • 4.5.1.6.2.1 Lignocellulosic wastes and residues
          • 4.5.1.6.2.2 Biorefinery lignin
        • 4.5.1.6.3 Third-generation (3-G)
          • 4.5.1.6.3.1 Algal biofuels
            • 4.5.1.6.3.1.1 Properties
            • 4.5.1.6.3.1.2 Advantages
        • 4.5.1.6.4 Fourth-generation (4-G)
        • 4.5.1.6.5 Energy crops
        • 4.5.1.6.6 Agricultural residues
        • 4.5.1.6.7 Manure, sewage sludge and organic waste
        • 4.5.1.6.8 Forestry and wood waste
        • 4.5.1.6.9 Feedstock costs
      • 4.5.1.7 Synthetic biology approaches for biofuel production
      • 4.5.1.8 Bioethanol
        • 4.5.1.8.1 Ethanol to jet fuel technology
        • 4.5.1.8.2 Methanol from pulp & paper production
        • 4.5.1.8.3 Sulfite spent liquor fermentation
        • 4.5.1.8.4 Gasification
          • 4.5.1.8.4.1 Biomass gasification and syngas fermentation
          • 4.5.1.8.4.2 Biomass gasification and syngas thermochemical conversion
        • 4.5.1.8.5 CO2 capture and alcohol synthesis
        • 4.5.1.8.6 Biomass hydrolysis and fermentation
        • 4.5.1.8.7 Separate hydrolysis and fermentation
          • 4.5.1.8.7.1 Simultaneous saccharification and fermentation (SSF)
          • 4.5.1.8.7.2 Pre-hydrolysis and simultaneous saccharification and fermentation (PSSF)
          • 4.5.1.8.7.3 Simultaneous saccharification and co-fermentation (SSCF)
          • 4.5.1.8.7.4 Direct conversion (consolidated bioprocessing) (CBP)
      • 4.5.1.9 Biodiesel
      • 4.5.1.10 Biogas
        • 4.5.1.10.1 Biomethane
        • 4.5.1.10.2 Feedstocks
        • 4.5.1.10.3 Anaerobic digestion
      • 4.5.1.11 Renewable diesel
      • 4.5.1.12 Biojet fuel
      • 4.5.1.13 Algal biofuels (blue biotech)
        • 4.5.1.13.1 Conversion pathways
        • 4.5.1.13.2 Market challenges
        • 4.5.1.13.3 Prices
        • 4.5.1.13.4 Producers
      • 4.5.1.14 Biohydrogen
        • 4.5.1.14.1 Biological Conversion Routes
          • 4.5.1.14.1.1 Bio-photochemical Reaction
          • 4.5.1.14.1.2 Fermentation and Anaerobic Digestion
      • 4.5.1.15 Biobutanol
      • 4.5.1.16 Bio-based methanol
        • 4.5.1.16.1 Anaerobic digestion
        • 4.5.1.16.2 Biomass gasification
        • 4.5.1.16.3 Power to Methane
      • 4.5.1.17 Bioisoprene
      • 4.5.1.18 Fatty Acid Esters
    • 4.5.2 Bio-based chemicals
      • 4.5.2.1 Acetic acid
      • 4.5.2.2 Adipic acid
      • 4.5.2.3 Aldehydes
      • 4.5.2.4 Acrylic acid
      • 4.5.2.5 Bacterial cellulose
      • 4.5.2.6 1,4-Butanediol (BDO)
      • 4.5.2.7 Bio-DME
      • 4.5.2.8 Dodecanedioic acid (DDDA)
      • 4.5.2.9 Ethylene
      • 4.5.2.10 3-Hydroxypropionic acid (3-HP)
      • 4.5.2.11 1,3-Propanediol (1,3-PDO)
      • 4.5.2.12 Itaconic acid
      • 4.5.2.13 Lactic acid (D-LA)
      • 4.5.2.14 1,5-diaminopentane (DA5)
      • 4.5.2.15 Tetrahydrofuran (THF)
      • 4.5.2.16 Malonic acid
      • 4.5.2.17 Monoethylene glycol (MEG)
      • 4.5.2.18 Propylene
      • 4.5.2.19 Succinic acid (SA)
      • 4.5.2.20 Triglycerides
      • 4.5.2.21 Enzymes
      • 4.5.2.22 Vitamins
      • 4.5.2.23 Antibiotics
    • 4.5.3 Bioplastics and Biopolymers
      • 4.5.3.1 Polylactic acid (PLA)
      • 4.5.3.2 PHAs
        • 4.5.3.2.1 Commercial landscape
        • 4.5.3.2.2 Production biology
        • 4.5.3.2.3 Downstream processing
        • 4.5.3.2.4 Types
          • 4.5.3.2.4.1 PHB
          • 4.5.3.2.4.2 PHBV
        • 4.5.3.2.5 Synthesis and production processes
        • 4.5.3.2.6 Commercially available PHAs
      • 4.5.3.3 Bio-PET
      • 4.5.3.4 Starch blends
      • 4.5.3.5 Protein-based bioplastics
    • 4.5.4 Bioremediation
    • 4.5.5 Biocatalysis
      • 4.5.5.1 Biotransformations
      • 4.5.5.2 Cascade biocatalysis
      • 4.5.5.3 Co-factor recycling
      • 4.5.5.4 Immobilization
    • 4.5.6 Food and Nutraceutical Ingredients
      • 4.5.6.1 Alternative Proteins
      • 4.5.6.2 Natural Sweeteners
      • 4.5.6.3 Natural Flavors and Fragrances
      • 4.5.6.4 Texturants and Thickeners
      • 4.5.6.5 Nutraceuticals and Supplements
    • 4.5.7 Sustainable agriculture
      • 4.5.7.1 Crop Improvement and Trait Development
      • 4.5.7.2 Plant-Microbe Interactions and Symbiosis
      • 4.5.7.3 Biofertilizers
        • 4.5.7.3.1 Overview
        • 4.5.7.3.2 Companies
      • 4.5.7.4 Biopesticides
        • 4.5.7.4.1 Overview
        • 4.5.7.4.2 Companies
      • 4.5.7.5 Biostimulants
        • 4.5.7.5.1 Overview
        • 4.5.7.5.2 Companies
      • 4.5.7.6 Crop Biotechnology
        • 4.5.7.6.1 Genetic engineering
        • 4.5.7.6.2 Genome editing
        • 4.5.7.6.3 Companies
    • 4.5.8 Textiles
      • 4.5.8.1 Bio-Based Fibers
        • 4.5.8.1.1 Lyocell
        • 4.5.8.1.2 Bacterial cellulose
        • 4.5.8.1.3 Algae textiles
      • 4.5.8.2 Bio-based leather
        • 4.5.8.2.1 Properties of bio-based leathers
          • 4.5.8.2.1.1 Tear strength
          • 4.5.8.2.1.2 Tensile strength
          • 4.5.8.2.1.3 Bally flexing
        • 4.5.8.2.2 Comparison with conventional leathers
        • 4.5.8.2.3 Comparative analysis of bio-based leathers
      • 4.5.8.3 Plant-based leather
        • 4.5.8.3.1 Overview
        • 4.5.8.3.2 Production processes
          • 4.5.8.3.2.1 Feedstocks
          • 4.5.8.3.2.2 Agriculture Residues
          • 4.5.8.3.2.3 Food Processing Waste
          • 4.5.8.3.2.4 Invasive Plants
          • 4.5.8.3.2.5 Culture-Grown Inputs
          • 4.5.8.3.2.6 Textile-Based
          • 4.5.8.3.2.7 Bio-Composite
        • 4.5.8.3.3 Products
        • 4.5.8.3.4 Market players
      • 4.5.8.4 Mycelium leather
        • 4.5.8.4.1 Overview
        • 4.5.8.4.2 Production process
          • 4.5.8.4.2.1 Growth conditions
          • 4.5.8.4.2.2 Tanning Mycelium Leather
          • 4.5.8.4.2.3 Dyeing Mycelium Leather
        • 4.5.8.4.3 Products
        • 4.5.8.4.4 Market players
      • 4.5.8.5 Microbial leather
        • 4.5.8.5.1 Overview
        • 4.5.8.5.2 Production process
        • 4.5.8.5.3 Fermentation conditions
        • 4.5.8.5.4 Harvesting
        • 4.5.8.5.5 Products
        • 4.5.8.5.6 Market players
      • 4.5.8.6 Lab grown leather
        • 4.5.8.6.1 Overview
        • 4.5.8.6.2 Production process
        • 4.5.8.6.3 Products
        • 4.5.8.6.4 Market players
      • 4.5.8.7 Protein-based leather
        • 4.5.8.7.1 Overview
        • 4.5.8.7.2 Production process
        • 4.5.8.7.3 Commercial activity
      • 4.5.8.8 Recombinant Materials
      • 4.5.8.9 Sustainable Processing
    • 4.5.9 Packaging
      • 4.5.9.1 Polyhydroxyalkanoates (PHA)
      • 4.5.9.2 Applications
        • 4.5.9.2.1 Vials, bottles, and containers
        • 4.5.9.2.2 Disposable items and household goods
        • 4.5.9.2.3 Food packaging
        • 4.5.9.2.4 Wet wipes and diapers
      • 4.5.9.3 Proteins
      • 4.5.9.4 Algae-based
      • 4.5.9.5 Mycelium
      • 4.5.9.6 Antimicrobial films and agents
    • 4.5.10 Healthcare and Pharmaceuticals
      • 4.5.10.1 Drug discovery and development
      • 4.5.10.2 Gene therapy and regenerative medicine
      • 4.5.10.3 Vaccine production
      • 4.5.10.4 Personalized medicine
      • 4.5.10.5 Diagnostic tools and biosensors
      • 4.5.10.6 Companies
    • 4.5.11 Cosmetics
    • 4.5.12 Surfactants and detergents
    • 4.5.13 Construction materials
      • 4.5.13.1 Bioconcrete
      • 4.5.13.2 Microalgae biocement
      • 4.5.13.3 Mycelium materials
  • 4.6 Global market revenues 2019-2037
    • 4.6.1 By Technology
    • 4.6.2 By Product Type
    • 4.6.3 By Market
    • 4.6.4 By Region
  • 4.7 Scale-up and pilot infrastructure
  • 4.8 Natural molecule drug discovery
  • 4.9 Future Market Outlook

5 COMPANY PROFILES (327 company profiles)

6 APPENDIX

  • 6.1 Research Methodology
  • 6.2 Glossary of Terms

7 REFERENCES

List of Tables

  • Table 1. Comparison of synthetic biology and genetic engineering.
  • Table 2. Global Revenues for Synthetic Biology by Technology, 2019-2037 (Billion USD).
  • Table 3. Global Revenues for Synthetic Biology by Product Type, 2019-2037 (Billion USD).
  • Table 4. Global revenues for synthetic biology, by market, 2019-2037 (Billion USD).
  • Table 5. Global revenues for synthetic biology, by region, 2019-2037 (Billion USD).
  • Table 6. Major trends and drivers in synthetic biology.
  • Table 7. Investments in synthetic biology.
  • Table 8. Phase 1: Consolidation & Cost-Down (2027-2029).
  • Table 9. Phase 2: Integration & Scale (2030-2032).
  • Table 10. Phase 3: Transformation & Convergence (2033-2035).
  • Table 11. Phase 4: Maturation & Optimization (2036-2037).
  • Table 12. Convergence of synthetic biology, industrial enzymes and white biotechnology.
  • Table 13. Policy instruments shaping the 2027-2037 market.
  • Table 14. Differences between synthetic biology and conventional processes.
  • Table 15. Main application areas for synthetic biology.
  • Table 16. Advantages of synthetic biology.
  • Table 17. Key biomanufacturing processes utilized in synthetic biology.
  • Table 18. Molecules produced through industrial biomanufacturing.
  • Table 19. Continuous vs batch biomanufacturing
  • Table 20. Key fermentation parameters in batch vs continuous biomanufacturing processes.
  • Table 21. Synthetic biology fermentation processes.
  • Table 22. Cell-free versus cell-based systems
  • Table 23. Comparison of the biomanufacturing processes in synthetic biology.
  • Table 24. Major microbial cell factories used in industrial biomanufacturing.
  • Table 25. Core stages - Design, Build and Test.
  • Table 26. Key tools and techniques used in metabolic engineering for pathway optimization.
  • Table 27. Key applications of metabolic engineering.
  • Table 28. Main DNA synthesis technologies
  • Table 29. Main gene assembly methods.
  • Table 30. Key applications of genome engineering.
  • Table 31. Engineered proteins in industrial applications.
  • Table 32.Key computational tools and their applications in synthetic biology.
  • Table 33. Feedstocks for synthetic biology.
  • Table 34. Products from C1 feedstocks in white biotechnology.
  • Table 35. C2 Feedstock Products.
  • Table 36. CO2 derived products via biological conversion-applications, advantages and disadvantages.
  • Table 37. Production capacities of biorefinery lignin producers.
  • Table 38. Common starch sources that can be used as feedstocks for producing biochemicals.
  • Table 39. Biomass processes summary, process description and TRL.
  • Table 40. Pathways for hydrogen production from biomass.
  • Table 41. Overview of alginate-description, properties, application and market size.
  • Table 42. Blue biotechnology companies.
  • Table 43. Market trends and drivers in synthetic biology.
  • Table 44. Industry challenges and restraints in synthetic biology.
  • Table 45. Key markets and applications for synthetic biology.
  • Table 46. Comparison of biofuels.
  • Table 47. Categories and examples of solid biofuel.
  • Table 48. Comparison of biofuels and e-fuels to fossil and electricity.
  • Table 49. Classification of biomass feedstock.
  • Table 50. Biorefinery feedstocks.
  • Table 51. Feedstock conversion pathways.
  • Table 52. First-Generation Feedstocks.
  • Table 53. Lignocellulosic ethanol plants and capacities.
  • Table 54. Comparison of pulping and biorefinery lignins.
  • Table 55. Commercial and pre-commercial biorefinery lignin production facilities and processes
  • Table 56. Operating and planned lignocellulosic biorefineries and industrial flue gas-to-ethanol.
  • Table 57. Properties of microalgae and macroalgae.
  • Table 58. Yield of algae and other biodiesel crops.
  • Table 59. Range of biomass cost by feedstock type.
  • Table 60.  Processes in bioethanol production.
  • Table 61. Microorganisms used in CBP for ethanol production from biomass lignocellulosic.
  • Table 62. Biodiesel by generation.
  • Table 63. Biodiesel production techniques.
  • Table 64. Biofuel production cost from the biomass pyrolysis process.
  • Table 65. Biogas feedstocks.
  • Table 66. Advantages and disadvantages of Bio-aviation fuel.
  • Table 67. Production pathways for Bio-aviation fuel.
  • Table 68. Current and announced Bio-aviation fuel facilities and capacities.
  • Table 69. Algae-derived biofuel producers.
  • Table 70. Markets and applications for biohydrogen.
  • Table 71. Comparison of different Bio-H2 production pathways.
  • Table 72. Properties of petrol and biobutanol.
  • Table 73. Comparison of biogas, biomethane and natural gas.
  • Table 74. Biobased chemicals that can be produced using synthetic biology approaches.
  • Table 75. Applications of bio-based caprolactam.
  • Table 76. Applications of bio-based acrylic acid.
  • Table 77. Applications of bio-based 1,4-Butanediol (BDO).
  • Table 78. Applications of bio-based ethylene.
  • Table 79. Biobased feedstock sources for 3-HP.
  • Table 80. Applications of 3-HP.
  • Table 81. Applications of bio-based 1,3-Propanediol (1,3-PDO).
  • Table 82. Biobased feedstock sources for itaconic acid.
  • Table 83. Applications of bio-based itaconic acid.
  • Table 84. Biobased feedstocks that can be used to produce 1,5-diaminopentane (DA5).
  • Table 85. Applications of DN5.
  • Table 86. Applications of bio-based Tetrahydrofuran (THF).
  • Table 87. Markets and applications for malonic acid.
  • Table 88. Biobased feedstock sources for MEG.
  • Table 89. Applications of bio-based MEG.
  • Table 90. Applications of bio-based propylene.
  • Table 91. Biobased feedstock sources for Succinic acid.
  • Table 92. Applications of succinic acid.
  • Table 93. Bioplastics and bioplastic precursors synthesized via white biotechnology processes .
  • Table 94. Polylactic acid (PLA) market analysis-manufacture, advantages, disadvantages and applications.
  • Table 95. PLA producers and production capacities.
  • Table 96.Types of PHAs and properties.
  • Table 97. Comparison of the physical properties of different PHAs with conventional petroleum-based polymers.
  • Table 98. Polyhydroxyalkanoate (PHA) extraction methods.
  • Table 99. Commercially available PHAs.
  • Table 100. Types of protein based-bioplastics, applications and companies.
  • Table 101. Applications of white biotechnology in bioremediation and environmental remediation.
  • Table 102. Companies developing fermentation-derived food.
  • Table 103. Biofertilizer companies.
  • Table 104. Biopesticides companies.
  • Table 105. Biostimulants companies.
  • Table 106. Crop biotechnology companies.
  • Table 107. Types of sustainable alternative leathers.
  • Table 108. Properties of bio-based leathers.
  • Table 109. Comparison with conventional leathers.
  • Table 110. Price of commercially available sustainable alternative leather products.
  • Table 111. Comparative analysis of sustainable alternative leathers.
  • Table 112. Key processing steps involved in transforming plant fibers into leather materials.
  • Table 113. Current and emerging plant-based leather products.
  • Table 114. Companies developing plant-based leather products.
  • Table 115. Overview of mycelium-description, properties, drawbacks and applications.
  • Table 116. Companies developing mycelium-based leather products.
  • Table 117. Types of microbial-derived leather alternative.
  • Table 118. Companies developing microbial leather products.
  • Table 119. Companies developing plant-based leather products.
  • Table 120. Types of protein-based leather alternatives.
  • Table 121. Companies developing protein based leather.
  • Table 122. Applications, advantages and disadvantages of PHAs in packaging.
  • Table 123. Types of protein based-bioplastics, applications and companies.
  • Table 124. Overview of alginate-description, properties, application and market size.
  • Table 125. Pharmaceutical applications of synthetic biology.
  • Table 126. Companies involved in synthetic biology for gene therapy and regenerative medicine
  • Table 127. Companies involved in synthetic biology for vaccine production.
  • Table 128. Companies involved in synthetic biology for personalized medicine.
  • Table 129. Synthetic biology companies in healthcare and pharmaceuticals.
  • Table 130. Applications of biotechnology in the cosmetics industry.
  • Table 131. Sustainable biomanufacturing of surfactants and detergents.
  • Table 132. Global Revenues for Synthetic Biology by Technology, 2019-2037 (Billion USD).
  • Table 133. Global Revenues for Synthetic Biology by Product Type, 2019-2037 (Billion USD).
  • Table 134. Global revenues for synthetic biology, by market, 2019-2037 (Billion USD).
  • Table 135. Global revenues for synthetic biology, by region, 2019-2037 (Billion USD).
  • Table 136. Scale-up transition points and typical failure modes.
  • Table 137. Glossary of Terms.

List of Figures

  • Figure 1. Global Revenues for Synthetic Biology by Technology, 2019-2037 (Billion USD).
  • Figure 2. Global Revenues for Synthetic Biology by Product Type, 2019-2037 (Billion USD).
  • Figure 3. Global revenues for synthetic biology, by market, 2019-2037 (Billion USD).
  • Figure 4. Global revenues for synthetic biology, by region, 2019-2037 (Billion USD).
  • Figure 5. Industrial biotechnology value chain.
  • Figure 6. Cell-free and cell-based protein synthesis systems.
  • Figure 7. CRISPR/Cas9 & Targeted Genome Editing.
  • Figure 8. Genetic Circuit-Assisted Smart Microbial Engineering.
  • Figure 9. Microbial Chassis Development for Natural Product Biosynthesis.
  • Figure 10. LanzaTech gas-fermentation process.
  • Figure 11. Schematic of biological CO2 conversion into e-fuels.
  • Figure 12. Overview of biogas utilization.
  • Figure 13. Biogas and biomethane pathways.
  • Figure 14. Schematic overview of anaerobic digestion process for biomethane production.
  • Figure 15. BLOOM masterbatch from Algix.
  • Figure 16. SWOT analysis: synthetic biology.
  • Figure 17. Schematic of a biorefinery for production of carriers and chemicals.
  • Figure 19. Overview of biogas utilization.
  • Figure 20. Biogas and biomethane pathways.
  • Figure 21. Schematic overview of anaerobic digestion process for biomethane production.
  • Figure 22. Algal biomass conversion process for biofuel production.
  • Figure 23. Pathways for algal biomass conversion to biofuels.
  • Figure 24. Biobutanol production route.
  • Figure 25. Renewable Methanol Production Processes from Different Feedstocks.
  • Figure 26. Production of biomethane through anaerobic digestion and upgrading.
  • Figure 27. Production of biomethane through biomass gasification and methanation.
  • Figure 28. Production of biomethane through the Power to methane process.
  • Figure 29. Overview of Toray process.
  • Figure 30. Bacterial nanocellulose shapes
  • Figure 31. PHA family.
  • Figure 32. AlgiKicks sneaker, made with the Algiknit biopolymer gel.
  • Figure 33. Conceptual landscape of next-gen leather materials.
  • Figure 34. Hermes bag made of MycoWorks' mycelium leather.
  • Figure 35. Ganni blazer made from bacterial cellulose.
  • Figure 36. Bou Bag by GANNI and Modern Synthesis.
  • Figure 37. Paper cups lined with home-compostable PHA.
  • Figure 38. Amorphous PHA Cosmetics Jar.
  • Figure 39. Types of bio-based materials used for antimicrobial food packaging application.
  • Figure 40. Self-healing bacteria crack filler for concrete.
  • Figure 41. BioMason cement.
  • Figure 42. Microalgae based biocement masonry bloc.
  • Figure 43. Typical structure of mycelium-based foam.
  • Figure 44. Commercial mycelium composite construction materials.
  • Figure 45. Global Revenues for Synthetic Biology by Technology, 2019-2037 (Billion USD).
  • Figure 46. Global Revenues for Synthetic Biology by Product Type, 2019-2037 (Billion USD).
  • Figure 47. Global revenues for synthetic biology, by market, 2019-2037 (Billion USD).
  • Figure 48. Global revenues for synthetic biology, by region, 2019-2037 (Billion USD).
  • Figure 49. Jelly-like seaweed-based nanocellulose hydrogel.
  • Figure 50. Algiknit yarn.
  • Figure 51. ALGIECEL PhotoBioReactor.
  • Figure 52. BIOLO e-commerce mailer bag made from PHA.
  • Figure 53. Domsjo process.
  • Figure 54. Mushroom leather.
  • Figure 55. PHA production process.
  • Figure 56. Light Bio Bioluminescent plants.
  • Figure 57. Lignin gel.
  • Figure 58. BioFlex process.
  • Figure 59. TransLeather.
  • Figure 60. Reishi.
  • Figure 61. Compostable water pod.
  • Figure 62. Precision Photosynthesis™ technology.
  • Figure 63. Enfinity cellulosic ethanol technology process.
  • Figure 64. Fabric consisting of 70 per cent wool and 30 per cent Qmilk.
  • Figure 65. Lyocell process.
  • Figure 66. Spider silk production.
  • Figure 67. Corbion FDCA production process.
  • Figure 68. UPM biorefinery process.
  • Figure 69. The Proesa® Process.