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市場調查報告書
商品編碼
1871424
2021-2031年歐洲體外微電極陣列市場報告:範圍、細分、動態和競爭分析Europe Microelectrode Array In Vitro Market Report 2021-2031 by Scope, Segmentation, Dynamics, and Competitive Analysis |
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2023 年歐洲微電極陣列 (MEA) 體外市場價值約為 449 萬美元,預計到 2031 年將成長至 651 萬美元,在此期間的年複合成長率(CAGR) 為 4.7%。
推動這一市場發展的重要因素之一是人們越來越重視開發動物試驗模型的替代方案。雖然動物模型傳統上被用於生物醫學研究,以研究人類特有的疾病,但由於人類和動物藥物代謝有顯著差異,它們往往無法準確預測人類對藥物的反應。這種差異導致人們逐漸認知到,動物模型可能並不適用於所有類型的藥物毒性研究。此外,在國際零殘忍組織(Cruelty-Free International)和醫學實驗動物替代基金會(Fund for the Replacement of Animals in Medical Experiments)等倡導減少動物試驗的組織的推動下,歐洲和北美近期訂定的法規對動物試驗的使用施加了更嚴格的限制。這些監管變化正在推動微電極陣列在體外試驗中的應用,尤其是在製藥和生物技術領域,這些領域迫切需要更可靠的方法來評估藥物的神經毒性和心臟毒性。
像BMSEED這樣的製造商處於這項創新的前沿,提供諸如專有的可拉伸微電極陣列(sMEA)和MEASSuRE平台等先進產品。 sMEA旨在複製細胞的電學和力學環境,從而高度模擬體內條件。這種仿生法提高了體外實驗的有效性,在臨床前研究早期階段就能提供更準確、更貼近人體的資料,這有助於降低人體臨床試驗中常見的高失敗率。
歐洲體外微電極陣列市場按國家、產品和應用進行細分。本分析涵蓋的國家包括英國、德國、法國、義大利、西班牙以及歐洲其他地區。市場主要參與者正專注於策略發展,微電極陣列在研究中的日益普及,以及政府旨在改善醫療保健和醫學研究基礎設施的舉措,預計將推動市場成長。
德國在微電極陣列市場中處於領先地位,以其在神經生物學、心臟病學和藥物研發等領域的先進診斷工具和研究應用方面的卓越品質和創新而聞名。包括MaxWell Biosystems、Multi-Channel Systems和BMSEED在內的德國知名企業正積極進行研發,推出包括3D和CMOS技術在內的創新微電極陣列解決方案。此外,德國還實施了嚴格的動物實驗法規,這為向體外模型、類器官和晶片器官等替代測試技術的過渡提供了支持。
例如,位於圖賓根的3R中心因其開發器官晶片系統以替代動物實驗而榮獲2024年烏蘇拉·M·漢德爾動物福利獎,彰顯了其對創新研究的投入。此外,明斯特馬克斯·普朗克分子生物醫學研究所的研究人員開發了一種新型網狀微電極陣列,可促進腦類器官的生長和電生理分析,這對於研究阿茲海默症和帕金森氏症等疾病至關重要。在領先企業、先進研究機構和政府政策的支持下,德國市場可望顯著成長。
從市場細分來看,歐洲體外微電極陣列市場按產品類型、應用和國家/地區進行分類。產品類型包括傳統微電極陣列 (MEA)、多孔微電極陣列 (microwell-MEA) 和 CMOS 微電極陣列 (CMOS-MEA),其中多孔微電極陣列在 2023 年佔據最大的市場佔有率。從應用來看,市場分為心肌細胞、神經和其他類別,心肌細胞應用也佔據領先的市場。
微電極陣列體外市場的主要參與者包括Tucker Davis Technologies、SCREEN Holdings Co., Ltd.、Plexon Inc.、MaxWell Biosystems AG、Harvard Bioscience Inc.、Axion BioSystems Inc.、3Brain AG、NeuroNexus Technologies Inc.、MicroElectrodeDevices Inc.、Blackcocoon、NeuroNexus Technologies Inc。這些公司在推動該地區微電極陣列技術的開發和應用方面發揮著至關重要的作用。
The Europe microelectrode array (MEA) in vitro market was valued at approximately US$ 4.49 million in 2023 and is projected to grow to US$ 6.51 million by 2031, reflecting a compound annual growth rate (CAGR) of 4.7% during this period.
A significant driver of this market is the increasing emphasis on developing alternatives to animal testing models. While animal models have traditionally been used in biomedical research to study human-specific diseases, they often fail to accurately predict human drug responses due to substantial differences in drug metabolism between humans and animals. This discrepancy has led to a growing recognition that animal models may not be suitable for all types of drug toxicity studies. Furthermore, recent regulations in Europe and North America have imposed stricter limitations on the use of animals in research, driven by organizations such as Cruelty-Free International and the Fund for the Replacement of Animals in Medical Experiments, which advocate for the reduction of animal testing. These regulatory changes are propelling the adoption of microelectrode arrays for in vitro testing, particularly in the pharmaceutical and biotechnology sectors, where there is a push for more reliable methods to assess neurotoxicity and cardiotoxicity of drugs.
Manufacturers like BMSEED are at the forefront of this innovation, offering advanced products such as proprietary stretchable microelectrode arrays (sMEAs) and the MEASSuRE platform. The sMEAs are designed to replicate the electrical and mechanical environments of cells, closely mimicking in vivo conditions. This biomimetic approach enhances the validity of in vitro experiments, providing more accurate and human-relevant data early in the preclinical research phase, which can help reduce the high failure rates seen in human clinical trials.
The microelectrode array in vitro market in Europe is segmented by country, product, and application. The countries included in this analysis are the UK, Germany, France, Italy, Spain, and the Rest of Europe. Key players in the market are focusing on strategic developments, and the increasing use of microelectrode arrays in research, along with government initiatives aimed at improving healthcare and medical research infrastructure, are expected to drive market growth.
Germany stands out as a leader in the microelectrode array market, known for its quality and innovation in advanced diagnostic tools and research applications in fields such as neurobiology, cardiology, and drug discovery. Prominent companies in Germany, including MaxWell Biosystems, Multi-Channel Systems, and BMSEED, are actively engaged in R&D to introduce innovative microelectrode array solutions, including 3D and CMOS technologies. The country has also implemented stringent regulations regarding animal testing in biotechnology and pharmaceutical research, which supports the transition to alternative testing technologies like in vitro models, organoids, and organ-on-chips.
For instance, the 3R Center in Tubingen was awarded the Ursula M. Handel Animal Welfare Prize 2024 for its development of organ-on-chip systems as alternatives to animal testing, highlighting the commitment to innovative research. Additionally, researchers from the Max Planck Institute for Molecular Biomedicine in Munster have developed a novel mesh microelectrode array that enhances the growth and electrophysiological analysis of brain organoids, which are crucial for studying diseases like Alzheimer's and Parkinson's. This positions the German market for significant growth, bolstered by contributions from leading companies, advanced research institutions, and supportive government policies.
In terms of market segmentation, the Europe microelectrode array in vitro market is categorized by product type, application, and country. The product types include classical MEA, multiwell-MEA, and CMOS-MEA, with the multiwell-MEA segment holding the largest market share in 2023. In terms of application, the market is divided into cardiomyocytes, nerve, and other categories, with cardiomyocytes also leading in market share.
Key players in the microelectrode array in vitro market include Tucker Davis Technologies, SCREEN Holdings Co., Ltd., Plexon Inc., MaxWell Biosystems AG, Harvard Bioscience Inc., Axion BioSystems Inc., 3Brain AG, NeuroNexus Technologies Inc., MicroElectrodeDevices, Blackrock Microsystems, Inc., NMI Technologietransfer GmbH, and BMSEED. These companies are instrumental in advancing the development and application of microelectrode array technologies in the region.