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市場調查報告書
商品編碼
1803084
2032 年肝纖維化治療市場預測:按治療類型、疾病狀況、通路和地區進行的全球分析Liver Fibrosis Treatment Market Forecasts to 2032 - Global Analysis By Treatment Type, Condition, Distribution Channel and By Geography |
根據 Stratistics MRC 的數據,全球肝纖維化治療市場預計在 2025 年達到 207.1 億美元,預計到 2032 年將達到 488.7 億美元,預測期內的複合年成長率為 13.05%。
肝纖維化的治療旨在減少或逆轉持續性肝損傷和發炎引起的疤痕組織形成。治療包括控制潛在原因,例如病毒性肝炎、飲酒或非酒精性脂肪性肝病,並透過藥物治療、生活方式改變和支持性治療相結合的方式,最大限度地減少進一步的損害。及時治療可保護肝功能,減緩病情進展,降低肝硬化的風險,最終改善整體健康狀況和預後。
根據美國國家酒精濫用和酒精成癮研究所 (2023) 的數據,到 2022 年,美國將有約 2,950 萬人遭受酒精成癮困擾,佔 12 歲及以上人口的 10.5%。
老年人口不斷增加
全球人口老化顯著推動了肝纖維化治療的需求。由於老齡化相關的免疫力減弱以及長期暴露於代謝壓力源,老年人更容易受到肝損傷。肥胖、糖尿病和心臟病等疾病通常並存,並加速肝臟功能惡化。隨著人們壽命的延長,醫療保健提供者發現老年患者需要客製化治療方法。這一趨勢正在推動醫藥創新,專注於為老年人提供更安全、更有效的抗纖維化藥物選擇。最終,人口老化正在擴大治療市場,並影響臨床開發的方向。
核准的抗纖維化藥物供應有限
大多數現有療法著重於控制潛在病因,例如病毒性肝炎和脂肪肝,而非逆轉纖維化疾病。複雜的監管和漫長的研發週期阻礙了新治療方法的推廣。許多有前景的化合物仍處於早期研究階段,導致臨床醫生難以找到合適的治療方案。這種藥物短缺影響了患者護理,並限制了市場擴張,尤其是在高負擔地區。在更多抗纖維化藥物核准之前,治療方案可能仍然有限。
遠端醫療和數位健康平台的擴展
數位醫療和遠端醫療的興起為肝纖維化的管理開闢了新的途徑。虛擬會診使患者能夠聯繫肝病專家並獲得及時治療,尤其是在偏遠和服務不足的地區。穿戴式裝置和行動應用程式可以監測肝功能指標並支持藥物依從性。這些技術還能實現個人化治療方案,改善病患教育,並促進更好的健康結果。隨著數位醫療成為主流,肝纖維化的治療正變得更加積極且易於獲得。預計這一轉變將促進創新治療方法的廣泛應用,並加強疾病管理。
來自替代療法的競爭
替代療法正日益挑戰傳統肝纖維化治療的優勢。生活型態改變、飲食介入和代謝控制等預防策略正逐漸成為第一線治療手段。再生技術和細胞療法也提供了繞過傳統藥物治療的全新解決方案。這些日益廣泛的治療選擇或許可以減少對藥物介入的依賴。此外,如果非侵入性方法被證明有效,臨床醫生在採用新藥時可能會更加謹慎。
COVID-19疫情對肝纖維化治療市場造成了顯著影響,導致診斷、常規檢查和不必要的醫療程序延誤。治療計劃經常被推遲,這可能導致部分患者的病情惡化。供應鏈中斷阻礙了藥品和診斷工具的供應。 COVID-19對肝功能的潛在影響凸顯了早期發現和有效治療的重要性。
過氧化物酶體增殖劑部分預計將在預測期內成為最大的
由於高通量篩檢和分子建模等藥物發現技術的進步,過氧化物酶體增殖物領域預計將在預測期內佔據最大的市場佔有率。諸如雙PPAR促效劑和泛PPAR促效劑的開發等新興趨勢提供了更廣泛的治療益處。關鍵進展包括令人鼓舞的臨床試驗結果以及製藥公司之間為加速創新而建立的策略聯盟。非酒精性脂肪性肝炎(NASH)及其相關代謝紊亂的盛行率不斷上升,使得基於PPAR的療法成為肝纖維化管理的關鍵領域,從而進一步推動需求。
預計醫院藥房部門在預測期內將出現最高的複合年成長率。
隨著自動配藥和電子處方系統等配藥技術的進步,醫院藥局預計將在預測期內實現最高成長率。新興趨勢包括整合遠距配藥服務以及針對肝病患者的個人化醫療方案。此外,醫院與製藥公司合作進行臨床試驗以及加速藥物可及性計畫等發展也取得了進展。肝臟相關疾病住院率的上升以及先進治療方法的日益普及,進一步加強了醫院藥房在醫療服務中的作用。
由於與肝炎、非酒精性脂肪性肝炎 (NASH) 和酒精性肝損傷相關的病例增加,預計亞太地區將在預測期內佔據最大的市場佔有率。非侵入性成像和 RNA 療法的技術創新正在增強早期診斷和標靶治療。市場對數位健康和個人化治療方法的採用正在成長。值得注意的發展包括印度、日本和中國候選藥物和測試活動的擴展。人口老化、健康意識的增強以及政府投資的增加正在推動技術進步和區域市場的成長。
在預測期內,北美預計將見證最高的複合年成長率,這得益於北美強大的醫療體系和研究資金的支持,以及NASH、NAFLD和肝炎的盛行率不斷上升。人工智慧主導的診斷、非侵入性技術和RNA療法的突破正在提高準確性和早期療育。遠端醫療和個人化治療等趨勢也在推動市場發展。最近的發展包括新的PPAR標靶藥物、聯合治療和不斷擴大的臨床試驗網路。不斷提高的健康素養、有利的法規和活躍的藥物研發線正在推動全部區域市場的持續擴張。
According to Stratistics MRC, the Global Liver Fibrosis Treatment Market is accounted for $20.71 billion in 2025 and is expected to reach $48.87 billion by 2032 growing at a CAGR of 13.05% during the forecast period. Treatment for liver fibrosis targets the reduction or reversal of scar tissue formation resulting from ongoing liver damage or inflammation. It involves managing the root cause like viral hepatitis, alcohol consumption, or nonalcoholic fatty liver alongside medications, lifestyle modifications, and supportive care to minimize further harm. Timely treatment helps preserve liver function, slows disease progression, and lowers the risk of developing cirrhosis, ultimately improving overall health and prognosis.
According to the National Institute on Alcohol Abuse and Alcoholism 2023, in 2022, about 29.5 million individuals in the United States with alcohol dependence, or 10.5% of individuals aged between 12 years and above.
Growing geriatric population
The increasing number of elderly individuals worldwide is significantly boosting demand for liver fibrosis treatments. Older adults are more prone to liver disorders due to age-related immune decline and long-term exposure to metabolic stressors. Conditions like obesity, diabetes, and heart disease often coexist, accelerating liver deterioration. As longevity rises, healthcare providers are seeing a growing need for therapies tailored to older patients. This trend is encouraging pharmaceutical innovation focused on safer and more effective anti-fibrotic options for seniors. Eventually, the aging demographic is expanding the treatment market and influencing the direction of clinical development.
Limited availability of approved anti-fibrotic drugs
Most available therapies concentrate on managing underlying causes such as viral hepatitis or fatty liver disease, rather than reversing fibrotic damage. Regulatory complexities and extended development timelines have slowed the introduction of new treatments. Many promising compounds are still in early research phases, leaving clinicians with few targeted solutions. This shortage affects patient care and restricts market expansion, particularly in high-burden regions. Until more anti-fibrotic agents receive approval, treatment options will remain constrained.
Expansion of telemedicine and digital health platforms
The rise of digital health and telemedicine is opening new avenues for managing liver fibrosis. Virtual consultations allow patients to access liver specialists and receive timely care, especially in remote or underserved areas. Wearables and mobile apps can monitor liver function indicators and support medication adherence. These technologies also enable customized treatment plans and improve patient education, fostering better health outcomes. As digital healthcare becomes mainstream, liver fibrosis care is becoming more proactive and accessible. This shift is expected to drive broader adoption of innovative therapies and enhance disease management.
Competition from alternative therapies
Alternative therapies are increasingly challenging the dominance of traditional liver fibrosis treatments. Preventive strategies like lifestyle changes, dietary interventions, and metabolic control are gaining traction as first-line approaches. Regenerative techniques and cell-based therapies also offer novel solutions that may bypass conventional drug treatments. This expanding range of options could reduce reliance on pharmacological interventions. Additionally, clinicians may be cautious about adopting new drugs if non-invasive methods prove effective.
The COVID-19 pandemic had a notable effect on the Liver Fibrosis Treatment Market, causing delays in diagnostics, routine check-ups, and non-essential medical procedures. Treatment schedules were often postponed, resulting in possible disease advancement for some patients. Disruptions in supply chains hindered the availability of medicines and diagnostic tools. On the positive side, the crisis spurred the adoption of telemedicine and heightened awareness of liver health, as COVID-19's potential impact on liver function emphasized the importance of early detection and effective care.
The peroxisome proliferator segment is expected to be the largest during the forecast period
The peroxisome proliferator segment is expected to account for the largest market share during the forecast period, driven by advancements in drug discovery technologies, including high-throughput screening and molecular modelling. Emerging trends such as the development of dual and pan-PPAR agonists offer broader therapeutic benefits. Key developments include promising clinical trial results and strategic collaborations between pharmaceutical companies to accelerate innovation. Increasing prevalence of nonalcoholic steatohepatitis (NASH) and related metabolic disorders further fuels demand, positioning PPAR-based treatments as a vital segment in liver fibrosis management.
The hospital pharmacies segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the hospital pharmacies segment is predicted to witness the highest growth rate, driven by advancements in pharmaceutical dispensing technologies, such as automated drug distribution and electronic prescription systems, enhancing efficiency and accuracy. Emerging trends include integration of telepharmacy services and personalized medicine approaches for liver disease patients. Developments like hospital collaborations with pharmaceutical companies for clinical trials and early drug access programs. Rising hospitalization rates for liver-related conditions and increasing availability of advanced therapies further strengthen the role of hospital pharmacies in treatment delivery.
During the forecast period, the Asia Pacific region is expected to hold the largest market share, due to escalating cases linked to hepatitis, NASH, and alcohol-induced liver damage. Innovations in non-invasive imaging and RNA therapeutics are enhancing early diagnosis and targeted care. The market is seeing growth in digital health adoption and personalized treatment approaches. Notable progress includes new drug candidates and expanded trial activity in India, Japan, and China. Aging populations, rising health awareness, and increased government investment are fueling technological advancement and regional market growth.
Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, due to growing prevalence of NASH, NAFLD, and hepatitis, supported by robust healthcare systems and research funding. Breakthroughs in AI-driven diagnostics, non-invasive technologies, and RNA therapeutics are improving accuracy and early intervention. Trends like telemedicine and tailored treatment approaches are gaining traction. Recent progress includes new PPAR-targeting drugs, multi-modal regimens, and expanded trial networks. Rising health literacy, favourable regulations, and active pharmaceutical pipelines are driving sustained market expansion across the region.
Key players in the market
Some of the key players in Liver Fibrosis Treatment Market include Abbott Laboratories, Bristol-Myers Squibb Company, Akero Therapeutics, Hepion Pharmaceuticals, Alentis Therapeutics, Inventiva Pharma, Alnylam Pharmaceuticals, Johnson & Johnson, Astellas Pharma Inc., Novartis AG, Boehringer Ingelheim, Merck & Co., Inc., Pfizer Inc., Sanofi AG, Vertex Pharmaceuticals Incorporated, Galectin Therapeutics, Inc., Takeda Pharmaceutical Company, Gilead Sciences, Inc., Madrigal Pharmaceuticals, Inc., and GlaxoSmithKline PLC.
In July 2025, Johnson & Johnson MedTech announced a strategic co-promotion agreement with Pacira BioSciences, Inc., the industry leader in the delivery of innovative, non-opioid pain therapies. The agreement expands the Company's Early Intervention portfolio with ZILRETTA(R) (triamcinolone acetonide extended-release injectable suspension) an extended-release injectable for treatment of pain related to osteoarthritis (OA) of the knee.
In June 2025, Bristol Myers Squibb and BioNTech SE announced that the companies have entered into an agreement for the global co-development and co-commercialization of BioNTech's investigational bispecific antibody BNT327 across numerous solid tumor types. Under the agreement, BioNTech and BMS will work jointly to broaden and accelerate the development of this clinical candidate.
In February 2025, Abbott and Shedd Aquarium are announcing one of Shedd's largest corporate gifts in recent history - a $10 million pledge from Abbott and Abbott's philanthropic foundation, Abbott Fund. The investment cements the longstanding partnership between Shedd, Abbott, and Abbott Fund to enrich the cultural, educational and environmental fabric of Chicago and spark passion for protecting the ocean environment.