全球酒精性肝病市場：依適應症、地區和國家分析和預測（2025 年至 2035 年）

酒精性肝病 (ARLD) 市場的主要促進因素之一是全球過量飲酒的增加。

隨著酗酒和重度飲酒現象持續上升，尤其是在年輕一代中，酒精性脂肪肝 (AFLD)、酒精性肝炎、肝硬化和肝功能衰竭等肝臟相關疾病的發生率也在上升。這一趨勢促使對有效治療方案和干涉措施的需求增加，從而推動了市場的發展。此外，社會對酒精對肝臟不良影響的認知不斷提高，診斷技術和支持早期發現和治療的藥物研發的進步，也進一步推動了市場的成長。

然而，ARLD 市場的成長面臨許多課題。其中最大的課題之一是疾病的延遲診斷和漏報。許多人並不了解這種疾病，尤其是在酒精性脂肪肝 (AFLD) 等早期階段，因為幾乎沒有任何主觀症狀。通常只有在疾病發展到肝炎或肝硬化等嚴重階段後才被診斷出來。這種延遲診斷限制了早期療育的有效性，並增加了需要肝臟移植等昂貴且侵入性治療的風險。此外，社會對酗酒和肝病的偏見也阻礙了患者尋求治療。在此背景下，雖然先進的治療方法正在開發中，但缺乏廣泛的早期檢測是市場成長的主要障礙。

市場區隔

部門一：依適應症

• 酒精性脂肪肝
• 酒精性肝炎
• 肝纖維化
• 肝硬化

部門2：依地區

• 北美洲
• 歐洲
• 亞太地區
• 其他地區

本報告調查了全球酒精相關肝病市場，並總結了主要趨勢、市場影響因素分析、法律制度、技術和專利分析、市場規模趨勢和預測、各個部門市場、地區/主要國家的詳細分析、競爭格局和主要企業的概況。

目錄

執行摘要

第1章全球酒精性肝病市場：產業展望

• 市場趨勢
• 法律規範
• 流行病學分析
• 臨床試驗分析
• 市場動態
  • 影響分析
  • 市場促進因素
  • 市場課題
  • 市場機會

2. 全球酒精性肝病市場（依適應症）

• 酒精性脂肪肝
• 酒精性肝炎
• 肝纖維化
• 肝硬化

3. 全球酒精性肝病市場（依地區）

• 北美洲
• 歐洲
• 亞太地區
  • 主要發現
  • 市場動態
  • 市場規模及預測

4. 全球酒精性肝病市場：競爭格局與公司概況

• 關鍵策略和發展
  • M&A
  • 協同效應活動
  • 業務擴展和資金籌措
  • 產品發布和核准
  • 其他活動
• 公司簡介
  • Merck KGaA
  • Pfizer Inc.
  • Novartis AG
  • AbbVie Inc.
  • Gilead Sciences Inc.
  • Intercept Pharmaceuticals
  • Durect

第5章調查方法

Global Alcohol Related Liver Disease Market, Analysis and Forecast: 2025-2035

Alcohol-related liver disease (ARLD) is a spectrum of liver conditions that develop due to excessive alcohol consumption over time. The disease ranges from early-stage conditions such as alcoholic fatty liver disease (AFLD) to more advanced stages, such as alcoholic hepatitis, liver fibrosis, and cirrhosis. Alcohol-related liver disease occurs because the liver, which is responsible for processing alcohol, becomes overwhelmed and damaged by excessive intake. In the early stages, fatty deposits build up in the liver cells (AFLD), but as the disease progresses, it can lead to inflammation (alcoholic hepatitis), scarring (fibrosis), and eventually irreversible damage (cirrhosis), which severely impairs liver function. If left untreated, Alcohol-related liver disease can result in liver failure and increase the risk of liver cancer. Early diagnosis and lifestyle changes, such as reducing or ceasing alcohol consumption, are crucial for managing the disease and preventing its progression to more severe stages.

One of the key drivers of the alcohol-related liver disease (ARLD) market is the increasing prevalence of excessive alcohol consumption worldwide. As binge drinking and heavy alcohol use continue to rise, particularly among younger populations, the incidence of liver-related diseases such as alcoholic fatty liver disease (AFLD), alcoholic hepatitis, cirrhosis, and liver failure is also growing. This trend is leading to higher demand for effective treatment options and interventions, driving the market for Alcohol-related liver disease therapies. Additionally, greater public awareness of the harmful effects of alcohol on liver health, combined with advancements in diagnostic technologies and drug development, is encouraging early detection and treatment, further boosting market growth.

Despite the growth of the alcohol-related liver disease (ARLD) market, several challenges continue to impede its full potential. One major challenge is the late-stage diagnosis and underreporting of the disease. Alcohol-related liver disease, particularly in its early stages such as alcoholic fatty liver disease (AFLD), often presents with no symptoms, leading many individuals to remain unaware of their condition until it progresses to more severe stages such as alcoholic hepatitis or cirrhosis. This delay in diagnosis limits the effectiveness of early intervention, which is crucial for preventing further liver damage and reducing the need for costly treatments such as liver transplantation. Additionally, the social stigma surrounding alcohol use and liver disease can discourage individuals from seeking medical help, further exacerbating the problem. As a result, while treatments for advanced Alcohol-related liver disease are improving, the lack of widespread early detection remains a significant barrier to realizing the full potential of the market.

The global alcohol-related liver disease (ARLD) market is highly competitive, with several key players driving innovation and market growth. Leading companies such as Merck KGaA, Pfizer Inc., Novartis AG, AbbVie Inc., Gilead Sciences Inc., Intercept Pharmaceuticals, and Durect are at the forefront of developing cutting-edge therapies and advancing research. These companies are focusing on expanding their product portfolios to include novel drugs targeting the various stages of alcohol-related liver disease, including antifibrotic agents, anti-inflammatory treatments, and liver-protective therapies. Their commitment to innovation, alongside strategic partnerships and collaborations, is helping accelerate the development of effective treatments for alcohol-related liver disease. With the increasing prevalence of alcohol consumption and growing awareness of liver health, these industry leaders are well-positioned to capture a significant share of the alcohol-related liver disease market while improving patient outcomes through advanced therapeutic options.

Market Segmentation:

Segmentation 1: by Indication

• Alcoholic Fatty Liver Disease
• Alcoholic Liver Hepatitis
• Liver Fibrosis
• Liver Cirrhosis

Segmentation 2: by Region

• North America
• Europe
• Asia-Pacific
• Rest of the World

The global alcohol-related liver disease (ARLD) market is experiencing several key emerging trends that are reshaping the landscape, driving growth, and improving patient outcomes. One of the most significant trends is the growing focus on early diagnosis and detection. With advancements in non-invasive diagnostic technologies, such as biomarker-based blood tests and advanced imaging techniques, healthcare providers are now able to identify liver conditions such as alcoholic fatty liver disease (AFLD) at earlier stages, allowing for timely interventions. Another key trend is the development of targeted therapies, particularly antifibrotic agents for cirrhosis and novel treatments for alcoholic hepatitis, which are expanding the treatment options available to patients. Additionally, there is an increased emphasis on personalized medicine, with therapies being tailored to individual patients based on their unique genetic profiles and disease progression. The market is also being reshaped by rising public awareness of the impact of alcohol on liver health, coupled with public health initiatives aimed at reducing excessive alcohol consumption. Finally, the growing availability of liver transplantation and advancements in regenerative medicine are offering hope for patients with end-stage liver disease, contributing to the market's overall expansion.

Table of Contents

Executive Summary

Scope and Definition

Market/Product Definition

Inclusion and Exclusion

Key Questions Answered

Analysis and Forecast Note

1. Global Alcohol Related Liver Disease Market: Industry Outlook

• 1.1 Introduction
• 1.2 Market Trends
• 1.3 Regulatory Framework
• 1.4 Epidemiology Analysis
• 1.5 Clinical Trial Analysis
• 1.6 Market Dynamics
  • 1.6.1 Impact Analysis
  • 1.6.2 Market Drivers
  • 1.6.3 Market Challenges
  • 1.6.4 Market Opportunities

2. Global Alcohol Related Liver Disease Market (Indication), ($Billion), 2023-2035

• 2.1 Alcoholic Fatty Liver Disease
• 2.2 Alcoholic Liver Hepatitis
• 2.3 Liver Fibrosis
• 2.4 Liver Cirrhosis

3. Global Alcohol Related Liver Disease Market (Region), ($Billion), 2023-2035

• 3.1 North America
  • 3.1.1 Key Findings
  • 3.1.2 Market Dynamics
  • 3.1.3 Market Sizing and Forecast
    • 3.1.3.1 North America Alcohol Related Liver Disease Market, by Country
      • 3.1.3.1.1 U.S.
• 3.2 Europe
  • 3.2.1 Key Findings
  • 3.2.2 Market Dynamics
  • 3.2.3 Market Sizing and Forecast
    • 3.2.3.1 Europe Alcohol Related Liver Disease Market, by Country
      • 3.2.3.1.1 Germany
      • 3.2.3.1.2 U.K.
      • 3.2.3.1.3 France
      • 3.2.3.1.4 Italy
• 3.3 Asia Pacific
  • 3.3.1 Key Findings
  • 3.3.2 Market Dynamics
  • 3.3.3 Market Sizing and Forecast
    • 3.3.3.1 Asia Pacific Alcohol Related Liver Disease Market, by Country
      • 3.3.3.1.1 China
      • 3.3.3.1.2 Japan

4. Global Alcohol Related Liver Disease Market: Competitive Landscape and Company Profiles

• 4.1 Key Strategies and Development
  • 4.1.1 Mergers and Acquisitions
  • 4.1.2 Synergistic Activities
  • 4.1.3 Business Expansions and Funding
  • 4.1.4 Product Launches and Approvals
  • 4.1.5 Other Activities
• 4.2 Company Profiles
  • 4.2.1 Merck KGaA
    • 4.2.1.1 Overview
    • 4.2.1.2 Top Products / Product Portfolio
    • 4.2.1.3 Top Competitors
    • 4.2.1.4 Target Customers/End-Users
    • 4.2.1.5 Key Personnel
    • 4.2.1.6 Analyst View
  • 4.2.2 Pfizer Inc.
    • 4.2.2.1 Overview
    • 4.2.2.2 Top Products / Product Portfolio
    • 4.2.2.3 Top Competitors
    • 4.2.2.4 Target Customers/End-Users
    • 4.2.2.5 Key Personnel
    • 4.2.2.6 Analyst View
  • 4.2.3 Novartis AG
    • 4.2.3.1 Overview
    • 4.2.3.2 Top Products / Product Portfolio
    • 4.2.3.3 Top Competitors
    • 4.2.3.4 Target Customers/End-Users
    • 4.2.3.5 Key Personnel
    • 4.2.3.6 Analyst View
  • 4.2.4 AbbVie Inc.
    • 4.2.4.1 Overview
    • 4.2.4.2 Top Products / Product Portfolio
    • 4.2.4.3 Top Competitors
    • 4.2.4.4 Target Customers/End-Users
    • 4.2.4.5 Key Personnel
    • 4.2.4.6 Analyst View
  • 4.2.5 Gilead Sciences Inc.
    • 4.2.5.1 Overview
    • 4.2.5.2 Top Products / Product Portfolio
    • 4.2.5.3 Top Competitors
    • 4.2.5.4 Target Customers/End-Users
    • 4.2.5.5 Key Personnel
    • 4.2.5.6 Analyst View
  • 4.2.6 Intercept Pharmaceuticals
    • 4.2.6.1 Overview
    • 4.2.6.2 Top Products / Product Portfolio
    • 4.2.6.3 Top Competitors
    • 4.2.6.4 Target Customers/End-Users
    • 4.2.6.5 Key Personnel
    • 4.2.6.6 Analyst View
  • 4.2.7 Durect
    • 4.2.7.1 Overview
    • 4.2.7.2 Top Products / Product Portfolio
    • 4.2.7.3 Top Competitors
    • 4.2.7.4 Target Customers/End-Users
    • 4.2.7.5 Key Personnel
    • 4.2.7.6 Analyst View

5. Research Methodology

List of Figures

• Figure: Global Alcohol Related Liver Disease Market (by Region), $Billion, 2024 and 2035
• Figure: Global Alcohol Related Liver Disease Market Key Trends, Analysis

List of Tables

• Table: Global Alcohol Related Liver Disease Market Dynamics, Impact Analysis
• Table: Global Alcohol Related Liver Disease Market (by Region), $Billion, 2024-2035
• Table: Global Alcohol Related Liver Disease Market (by Indication), $Billion, 2024-2035