![]() |
市場調查報告書
商品編碼
1383409
2030 年融合蛋白市場預測:按類型、應用和地區分類的全球分析Fusion Proteins Market Forecasts to 2030 - Global Analysis By Type (Immunoglobulin Fusion Protein, Parathyroid Hormone Fusion Protein, Cytokines Recombinant Fusion Protein and Other Types), By Application and By Geography |
根據 Stratistics MRC 的數據,2023 年全球融合蛋白市場規模將達到 298 億美元,預計到 2030 年將達到 454 億美元,預測期內年複合成長率為 6.2%。
融合蛋白是透過連接兩個或多個編碼單獨蛋白質的基因而製成的人造蛋白質。這些混合蛋白用於多種應用,包括生物技術和醫學。在生物技術中,融合蛋白用於生產大量用於研究或治療目的的特定蛋白質。它們也可以用作蛋白質精製的分子標籤或作為研究蛋白質相互作用的工具。
根據 Globocan 2020,新報告的癌症病例數為 19,292,789 例,預計到 2040 年將增加到 28,887,940 例。
隨著內容和分發管道變得越來越數位化,越來越需要保護寶貴的智慧財產權免受駭客攻擊、資料外洩和詐欺的分發等網路威脅。 DRM 解決方案提供強大的加密、存取控制和監控功能,使網路犯罪分子難以破壞或竊取敏感內容。因此,娛樂、出版和軟體開發等行業擴大採用 DRM 技術來保護自家公司資產,確保內容安全並降低因網路攻擊和盜版而造成收益損失的風險。
將融合蛋白療法推向市場所需的研究、開發和臨床試驗需要大量資金。這些成本包括臨床前測試、廣泛的臨床試驗、法規遵循、製造基礎設施等。高開發成本對於中小型生技公司來說尤其困難,並且會限制創新和競爭力。為了克服這些限制,合作研究、官民合作關係和資助計畫對於支持融合蛋白的研究和開發至關重要。此外,具有成本效益的開發策略和高效的臨床試驗設計可以幫助減輕這種經濟負擔,並最終加速這一重要治療領域的成長。
奈米顆粒、脂質體和綴合物等藥物遞送系統的改進為最佳化基於融合蛋白的治療藥物的給藥和療效提供了潛力。這些技術可以提高融合蛋白的穩定性、生物利用度以及向特定細胞和組織的標靶遞送,最大限度地減少脫靶效應,並提高整體治療效果。隨著藥物傳遞創新的不斷進行,融合蛋白療法對於多種疾病狀態將變得更具吸引力,因為它們不僅會擴大其適用性,而且會提高患者的依從性和舒適度,推動市場成長,並促進技術創新。
與其他生物製藥一樣,融合蛋白也存在副作用和意外後果的風險。確保此類治療方法的安全性至關重要,任何問題都可能導致法規挫折、公眾懷疑和市場不確定性。在臨床試驗期間對候選融合蛋白進行嚴格評估和監測對於降低這些風險至關重要。解決安全問題需要持續監測、藥物警戒和製定風險管理策略。最終,維持良好的效益風險比對於融合蛋白療法的市場接受度和長期成功至關重要。
COVID-19 大流行對融合蛋白市場產生了各種影響。雖然臨床試驗和供應鏈暫時中斷,但生物製藥研發的重要性卻凸顯出來。融合蛋白是治療性介入的多功能候選者,因此人們對其在 COVID-19 治療和疫苗開發方面的潛力越來越感興趣。此次疫情加速了生物技術研究,間接惠及融合蛋白部門。然而,對 COVID-19 相關治療的不確定性和關注暫時轉移了其他醫療條件的資源和注意力,影響了融合蛋白市場研發的整體步伐。
免疫球蛋白(Ig)融合部分預計將出現良好的成長。這些工程蛋白質將抗體的抗原特異性辨識與另一種感興趣的蛋白質或胜肽結合。 Ig融合蛋白廣泛應用於生物製藥,作為癌症、自體免疫疾病、感染疾病等多種疾病的標靶治療。此外,它也是診斷的重要工具,有助於準確檢測特定的生物標記。 Ig融合蛋白處於個人化醫療的最前沿,提供客製化的治療方案和創新的研究途徑,為融合蛋白市場的成長和開拓做出了重大貢獻。
預計生物技術產業在預測期內將以最快的年複合成長率成長。基因工程、重組 DNA 技術和蛋白質表現系統的進步使得能夠創造具有改善的治療特性的複雜融合蛋白。生物技術工具和技術有助於精確設計和修飾融合蛋白,以針對特定疾病或途徑。生技公司在這一領域不斷創新,並推動融合蛋白療法的成長。此外,生物技術的進步促進了高效製造、品管和新型藥物傳輸技術的開發,使融合蛋白成為現代生物製藥創新的基石。
在預測期內,由於北美市場先進的醫療基礎設施、強大的生物技術部門以及重要的研發活動,預計將繼續佔據大部分市場佔有率。尤其是美國和加拿大,處於基於融合蛋白的治療方法的創新和臨床試驗的前沿。這些國家擁有完善的法律規範和支持政策,鼓勵生物製藥的開發和商業化。此外,慢性病盛行率的不斷上升、對個人化醫療的日益重視以及對醫療保健研究的大量投資,都有助於該地區在融合蛋白市場中佔據主導地位。
亞太地區在香料蘭姆酒市場中發揮重要作用,預計在預測期內複合年複合成長率最高。該地區不斷擴大的製藥和生物技術行業以及龐大的患者群體帶來了巨大的商機。亞太地區的研發投資不斷增加,中國和印度等國家成為生物製藥生產中心。此外,慢性病的盛行率正在上升,推動了對創新治療方法(包括融合蛋白)的需求。亞太地區的市場成長潛力、臨床試驗和製造能力使其成為尋求進入該地區不斷擴大的醫療保健市場的全球生物製藥公司的重點關注點。
According to Stratistics MRC, the Global Fusion Proteins Market is accounted for $29.8 billion in 2023 and is expected to reach $45.4 billion by 2030 growing at a CAGR of 6.2% during the forecast period. Fusion proteins are artificial proteins created by joining two or more genes that code for separate proteins. These hybrid proteins serve various purposes, such as in biotechnology and medicine. In biotechnology, fusion proteins are used to produce specific proteins in large quantities for research or therapeutic purposes. They can also be utilized as molecular tags for protein purification or as tools for studying protein interactions.
According to Globocan 2020, there were 19,292,789 new cases of cancer reported, and this number is expected to increase to 28,887,940 by 2040.
With the growing digitization of content and distribution channels, there is a greater need to protect valuable intellectual property from cyber threats such as hacking, data breaches, and unauthorized distribution. DRM solutions offer robust encryption, access controls, and monitoring capabilities, making it harder for cybercriminals to compromise and steal sensitive content. As a result, industries like entertainment, publishing, and software development are increasingly adopting DRM technologies to safeguard their assets, ensuring content security and reducing the risk of revenue loss due to cyber attacks and piracy.
The research, development, and clinical testing required bringing fusion protein therapies to market demand substantial financial investment. These costs encompass preclinical studies, extensive clinical trials, regulatory compliance, and manufacturing infrastructure. High development expenses can be especially challenging for smaller biotech companies, potentially limiting their ability to innovate and compete. To overcome this restraint, collaboration, public-private partnerships, and funding initiatives are essential to support the research and development of fusion proteins. Additionally, cost-effective development strategies and efficient clinical trial design can help alleviate this financial burden, ultimately fostering the growth of this vital therapeutic sector.
Enhanced drug delivery systems, such as nanoparticles, liposomes, and conjugates, offer the potential to optimize the administration and effectiveness of fusion protein-based therapies. These technologies can improve the stability, bioavailability, and targeted delivery of fusion proteins to specific cells or tissues, minimizing off-target effects and enhancing overall treatment outcomes. As drug delivery innovations continue to evolve, they not only expand the applicability of fusion proteins but also enhance patient compliance and comfort, making fusion protein therapies more attractive for a wide range of medical conditions and thus driving market growth and innovation.
Fusion proteins, like all biopharmaceuticals, can carry risks of adverse reactions or unintended consequences. Ensuring the safety profile of these therapies is crucial, as any issues can lead to regulatory setbacks, public skepticism, and market uncertainty. The rigorous evaluation and monitoring of fusion protein candidates during clinical trials are essential to mitigate these risks. Addressing safety concerns demands continuous research, pharmacovigilance, and the development of risk management strategies. Ultimately, maintaining a favorable benefit-to-risk ratio is imperative for the market acceptance and long-term success of fusion protein therapies.
The COVID-19 pandemic has had mixed effects on the Fusion Proteins market. While it momentarily disrupted some clinical trials and supply chains, it also underscored the importance of biopharmaceutical research and development. Fusion proteins, being versatile candidates for therapeutic interventions, have seen increased interest in potential COVID-19 treatments and vaccine development. The pandemic has accelerated research in biotechnology, thereby indirectly benefiting the fusion proteins sector. However, the uncertainties and focus on COVID-19-related therapies temporarily diverted resources and attention from other medical conditions, impacting the overall pace of research and development in the Fusion Proteins market.
The immunoglobulin (Ig) fusion segment is expected to have a lucrative growth. These engineered proteins combine an antibody's antigen-specific recognition with another protein or peptide of interest. They find extensive use in biopharmaceuticals, offering targeted therapies for a variety of diseases, including cancers, autoimmune disorders, and infectious diseases. Additionally, they serve as indispensable tools in diagnostics, facilitating the precise detection of specific biomarkers. Ig Fusion Proteins are at the forefront of personalized medicine, providing tailored treatment options and innovative research avenues, contributing significantly to the growth and development of the Fusion Proteins market.
The biological technology segment is anticipated to witness the fastest CAGR growth during the forecast period. Advances in genetic engineering, recombinant DNA technology, and protein expression systems have enabled the creation of complex fusion proteins with enhanced therapeutic properties. Biotechnology tools and techniques facilitate the precise design and modification of fusion proteins to target specific diseases and pathways. Biotech companies are continuously innovating in this field, driving the growth of fusion protein therapies. Moreover, biotechnological advancements contribute to efficient manufacturing, quality control, and the development of novel drug delivery technologies, making fusion proteins a cornerstone of modern biopharmaceutical innovation.
During the forecast period, it is expected that the North American market will continue to hold a majority of the market share due to its advanced healthcare infrastructure, robust biotechnology sector, and significant research and development activities. The United States and Canada, in particular, have been at the forefront of innovation and clinical trials for fusion protein-based therapies. These nations have well-established regulatory frameworks and supportive policies that encourage the development and commercialization of biopharmaceuticals. Additionally, the increasing prevalence of chronic diseases, a growing emphasis on personalized medicine, and substantial investment in healthcare research contribute to the region's dominance in the Fusion Proteins market.
The Asia Pacific region plays a significant role in the spice rum market and is projected to have the highest CAGR over the forecast period. The region's expanding pharmaceutical and biotechnology industry, coupled with a large patient population, presents significant opportunities. Asia Pacific is witnessing increased investment in research and development, with countries like China and India becoming hubs for biopharmaceutical production. Furthermore, the prevalence of chronic diseases is on the rise, driving the demand for innovative therapies, including fusion proteins. Asia Pacific's potential for market growth, clinical trials, and manufacturing capabilities make it a key focus for global biopharmaceutical companies aiming to tap into the region's expanding healthcare market.
Some of the key players in Fusion Proteins market include: Abnova, Roche, Chimerigen, Peprotech, Amgen Science, Astellas Pharma, Bristol-Myers Squibb, ProSpec, Viventia, Genzyme, Ligand Pharmaceuticals, Novus, Regeneron, Origene and Absolute Antibody.
In August 2022, Amgen Inc. and Teneobio Inc. announced a deal in which Amgen would acquire Teneobio, which is a privately owned clinical-stage biotechnology firm focusing on a novel class of biologics known as Human Heavy-Chain Antibodies. Amgen's capabilities to develop advanced medicine in treating patients with severe diseases and commercialize best-in-class products will be strengthened by the acquisition of Teneobio.
In July 2022, Formation Biologics Inc., which is a protein engineering business specializing in biotherapeutics for cancer and fibrotic disorders was acquired by Bristol-Myers Squibb Company. Bristol-Myers Squibb acquired Forbius' TGF-beta program, including the lead experimental option, AVID200, as part of the acquisition. Primarily, Bristol-Myers Squibb intends to focus on AVID200 R&D in cancer detection, with the possibility of broadening its application to other therapeutic areas such as fibrosis.