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市場調查報告書
商品編碼
1856133
全球胜肽合成市場-市場佔有率和排名、總收入和需求預測(2025-2031 年)Peptide Synthesis - Global Market Share and Ranking, Overall Sales and Demand Forecast 2025-2031 |
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2024 年全球胜肽合成市場規模估計為 6.99 億美元,預計到 2031 年將達到 10.94 億美元,在 2025-2031 年預測期內複合年成長率為 6.7%。
胜肽合成是指利用化學或生物化學方法將特定序列的多個胺基酸連接成胜肽鏈的過程。這些胜肽可用作治療藥物、診斷劑、生物標記和研究工具。胜肽通常比蛋白質短,通常由不超過40-60個胺基酸殘基組成,但其結構可能很複雜,可能包含非天然或修飾的胺基酸、環化、與化學基團偶聯以及標記。主要的胜肽合成技術包括固相胜肽合成(SPPS)、液相胜肽合成(LPPS)、混合/匯聚合成法、酵素法和重組表現。合成流程通常包括胺基酸的保護和去保護、胜肽鍵形成(偶聯)、載體/樹脂錨定、純化(層析法步驟、沉澱等)以及嚴格的品管(結構確認、立體化學純度、雜質/殘留溶劑分析)。肽類藥物、診斷和化妝品應用的快速發展,以及對高特異性、低毒性和強生物相容性的需求不斷成長,使得肽合成成為生物製藥和生命科學研究與開發的關鍵組成部分。
目前,肽合成市場正處於曲折點。一方面,基於胜肽的療法在慢性病、代謝性疾病、腫瘤和神經退化等領域日益普及。其高特異性、低全身毒性和新型標靶機制使其在傳統小分子和大蛋白藥物難以發揮作用的領域展現出巨大潛力。另一方面,許多國家(例如美國、歐盟、日本和中國)的政府和監管機構已推出政策,支持創新,簡化新型胜肽和胜肽-寡核苷酸(TIDES)藥物的核准途徑,並縮短臨床試驗和監管審查時間,從而擴大了胜肽合成供應商的市場機會。在技術方面,固相合成(SPPS)、液相合成(LPPS)、混合/匯聚合成方法的不斷進步,以及複雜結構(包括非天然氨基酸、環化和胜肽-藥物偶聯物)合成能力的提升,正推動市場朝著更大規模、更高品質和更多樣化的結構發展。此外,下游CDMO/CRO外包需求正在迅速成長。藥物研發企業越來越傾向於將製程開發、規模化生產以及臨床/註冊生產外包給專業的合成/生產營業單位,以降低資本負擔和風險。新興經濟體(例如中國、印度和韓國)也是這一趨勢的強勁驅動力,這得益於不斷成長的醫療需求、對生物技術的投資、不斷下降的生產成本以及有利的政策激勵措施。
然而,肽合成市場並非沒有重大挑戰和風險。首先,合成長肽或複雜胜肽(例如,帶有修飾、非天然殘基、環化或疏水序列的胜肽)時,偶聯效率低、反應不完全、外消旋化和副產物生成等問題會被放大,導致產率降低,純化成本高且難度高。其次,上游原料(高純度保護胺基酸、專用耦合試劑、保護基以及稀有或合成修飾胺基酸)的供應鏈穩定性和成本差異很大。第三,下游純化和品管步驟(層析法、去除殘留試劑、保護基和溶劑、結構確認和立體化學純度測定)需要大量的資本投入、較長的週期和較高的營運成本,尤其是在臨床和商業規模上。各國對胜肽和生技藥品(或其他類別)的定義、監管標準以及環境和化學安全政策的差異,會增加合規成本並導致延誤。最後,競爭壓力和價格戰正在加劇,尤其是在 CDMO/合成服務供應商和以成本為導向的新興市場。
下游需求正朝著多個方向同步發展。治療性胜肽仍然是最大的驅動力。越來越多的胜肽類藥物獲得監管部門核准,研發開發平臺也不斷擴展,尤其是在代謝性疾病(如肥胖症、糖尿病)、腫瘤、內分泌調節和感染疾病等領域。肽-藥物偶聯物和胜肽疫苗已成為多個疾病領域的關鍵研究方向。除了治療性應用外,診斷和成像標記肽,例如生物標記、體外診斷試劑(IVD)以及放射性標記或螢光標記的小肽,需求也在不斷成長,尤其是在精準醫療領域。在化妝品/美容行業,具有抗衰老、修復、促進膠原蛋白生成和抗氧化等功能的胜肽正被積極引入市場,從而推動了消費者和品牌對天然、生物活性和安全成分的更高期望。在自動化和高通量合成工具的推動下,研究和基礎科學需求保持穩定,這促使學術機構和生物技術新興企業尋求更靈活、更快速的客製化胜肽合成服務。總體而言,下游需求正朝著更複雜的結構、更先進的改進、更高的純度和更客製化的應用方向發展,這要求更快的周轉時間和更高的服務品質。
本報告旨在全面概述全球胜肽合成市場,重點關注總銷售收入、市場佔有率和主要企業的排名,並按地區/國家、類型和應用進行分析。
胜肽合成市場規模、估算和預測報告提供了2020年至2031年期間的歷史數據和預測數據,以銷售收入(百萬美元)為單位,2024年為基準年。定量和定性分析有助於讀者制定業務/成長策略、評估市場競爭格局、分析公司在當前市場中的地位,並在胜肽合成領域做出明智的商業決策。
The global market for Peptide Synthesis was estimated to be worth US$ 699 million in 2024 and is forecast to a readjusted size of US$ 1094 million by 2031 with a CAGR of 6.7% during the forecast period 2025-2031.
Peptide synthesis refers to the process of linking multiple amino acids into a peptide chain in a specified sequence by chemical or biochemical methods. These peptides may serve as therapeutics, diagnostic reagents, biomarkers, or research tools. Peptides are generally shorter than proteins - most often composed of no more than 40-60 amino acid residues - though their structures can be complex, including non-natural or modified amino acids, cyclizations, conjugations with chemical moieties or labels. The main techniques for peptide synthesis include solid-phase peptide synthesis (SPPS), liquid-phase peptide synthesis (LPPS), hybrid/convergent methods, enzymatic or recombinant expression methods. The synthetic workflow typically involves protecting and deprotecting amino acids, peptide bond formation (coupling), support/resin anchoring or carrier systems, purification (such as chromatographic steps, precipitations, etc.), and rigorous quality control (structure confirmation, stereochemical purity, impurity/residual solvent analysis). With the rapid expansion of peptide-based drugs, diagnostics, and cosmetic applications, combined with growing demand for high specificity, low toxicity, and strong biocompatibility, peptide synthesis has become a cornerstone in biopharma and life science R&D.
The peptide synthesis market currently stands at a multi-accelerated inflection point. On one side, peptide-based therapeutics are being increasingly recognized in fields such as chronic diseases, metabolic disorders, oncology, and neurodegeneration: their high specificity, low systemic toxicity, and novel targeting mechanisms make them promising where traditional small molecules or large proteins struggle. On another side, governments and regulatory agencies in many countries (including the U.S., EU, Japan, China, etc.) are introducing policies that support innovation, streamline approval pathways for novel peptides or peptide/oligonucleotide (TIDES) drugs, and shorten clinical trial and regulatory review timelines, thereby enlarging market opportunity for peptide synthesis providers. On the technical front, continued progress in solid-phase synthesis (SPPS), liquid-phase methods (LPPS), hybrid / convergent synthesis, and enhanced capabilities for complex structures (including non-natural amino acids, cyclization, peptide-drug conjugates) are pushing the market toward larger scale, higher quality, and greater structural diversity. In addition, downstream CDMO/CRO outsourcing demand is rising sharply: drug developers are increasingly preferring to externalize process development, scale-up, and clinical/registration production to specialized synthesis/manufacturing entities to reduce capital burden and risk. Emerging economies (e.g. China, India, South Korea) are also providing strong growth drivers due to their rising healthcare needs, biotech investment, lower manufacturing cost bases, and favorable policy incentives.
However, the peptide synthesis market is not without substantial challenges and risks. First, synthesizing long or complex peptides (with modifications, non-natural residues, cyclization, hydrophobic sequences etc.) amplifies problems of low coupling efficiency, incomplete reactions, racemization, side-product formation - these reduce yield and make purification expensive and difficult. Second, the supply chain stability and cost volatility for upstream raw materials (high-purity protected amino acids, specialized coupling reagents, protective groups, rare or synthetic modified amino acids) is high; environmental / safety laws regulating chemical reagents and solvents impose increasing constraints. Third, downstream purification and quality control steps (chromatography, removal of residual reagents/protection groups/solvents, structure confirmation, stereochemical purity) require heavy equipment investment, long cycles, and high operating costs, particularly at clinical/commercial scale. Regulatory risk is also real: differing national definitions of peptides vs biologics (or other categories), regulatory standards, and environmental / chemical safety policies may shift, increasing compliance cost or causing delays. Finally, competitive pressures and pricing squeeze are intensifying, especially among CDMOs / synthesis service providers, and in emerging markets focusing on low cost; maintaining high quality, speed, and regulatory compliance becomes a differentiator but also a cost center.
Downstream demand is evolving in several concurrent directions. Therapeutic peptides continue to be the largest pull: more peptide drugs are gaining regulatory approval, and the R&D pipeline is expanding, especially in metabolic disease (e.g. obesity, diabetes), oncology, endocrine regulation, and infectious diseases. In several disease areas, peptide-drug conjugates and peptide vaccines are emerging as key focus areas. Beyond therapeutics, diagnostic and imaging labelled peptides are growing demand, e.g. biomarkers, in vitro diagnostics (IVD) and radiolabelled or fluorescent labelled small peptides, especially in precision medicine. The cosmetics / beauty sector is also actively introducing peptides with anti-aging, repair, collagen-boosting, antioxidative functionalities, with rising consumer and brand expectations for natural or bio-active, safety validated ingredients. Research and basic science needs remain stable, being driven by automation and high-throughput synthesis tools, giving academic institutions and biotech startups need for more flexible, fast, custom peptide synthesis services. Overall, downstream demand is trending toward more complex structures / high modifications / higher purity / more individualized use, and demands for faster turnaround and higher service quality.
This report aims to provide a comprehensive presentation of the global market for Peptide Synthesis, focusing on the total sales revenue, key companies market share and ranking, together with an analysis of Peptide Synthesis by region & country, by Type, and by Application.
The Peptide Synthesis market size, estimations, and forecasts are provided in terms of sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Peptide Synthesis.
Market Segmentation
By Company
Segment by Type
Segment by Application
By Region
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size. This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of Peptide Synthesis company competitive landscape, revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Revenue of Peptide Synthesis in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Revenue of Peptide Synthesis in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product revenue, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.