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市場調查報告書
商品編碼
1380413
全球胜肽藥物偶聯物市場2023-2030Global Peptide Drug Conjugates Market 2023-2030 |
預計全球胜肽藥物綴合物市場在預測期(2023-2030年)將以9.4%的CAGR成長。此市場歸因於癌症和代謝紊亂盛行率上升、新藥研發投資增加以及藥物開發技術進步等因素。根據 Globocan 2020,癌症病例數為 50,550,287 例。其中,全球新增病例總數19,292,789例。
全球胜肽藥物偶聯物市場按類型和產品細分。根據類型,市場分為診斷和治療。根據產品,市場細分為 Melflufen、Lutetium、ANG1005、BT1718 和 CBX-12。在這一類型中,由於新興的標靶治療藥物具有增強的腫瘤滲透性和選擇性,因此預計治療細分市場將佔據相當大的市場佔有率。
其中,melflufen細分市場預計將在全球胜肽藥物偶聯物市場中佔據相當大的佔有率。此細分市場的成長歸因於人們對當前治療選擇的認知不斷提高、有利的報銷政策、Melflufen 的推出以及PDC 藥物在癌症治療中的快速應用。2021 年2 月,FDA 批准了第一個抗癌胜肽藥物結合物,美法崙氟芬醯胺或美氟芬,與地塞米松合併使用。基於2期HORIZON研究,該產品由瑞典生物技術公司Oncopeptides AB開發,獲得加速批准。患有難治性多發性骨髓瘤的成年患者,曾經接受過至少 4 種治療,且其疾病對至少 1 種蛋白酶體抑制劑、1 種免疫調節劑和 1 種 CD38 定向單株抗體難以治療。
全球胜肽藥物偶聯物市場根據地理位置進一步細分,包括北美(美國和加拿大)、歐洲(英國、義大利、西班牙、德國、法國和歐洲其他地區)、亞太地區(印度、中國、日本、韓國和亞洲其他地區)以及世界其他地區(中東和非洲以及拉丁美洲)。其中,由於開發和商業化新輸送系統的投資不斷增加,預計亞太地區將在全球市場中佔據顯著佔有率。
在所有地區中,北美地區預計在預測期內將以相當大的CAGR成長。推動北美市場的主要因素是該地區癌症病例數量的增加,預計這肯定會影響未來幾年胜肽藥物綴合物市場的成長。根據美國癌症協會 (ACS) 的數據,2022 年,美國報告了約 1,918,030 例新癌症病例和 609,360 例癌症死亡病例。根據英國皇家學會出版組織報道,HPRP-A1-TAT是一種雜合胜肽,能破壞細胞膜,導致細胞質內容物快速滲漏,具有很強的抗癌活性。
服務全球胜肽藥物綴合物市場的主要公司包括: Angiochem Inc.、Bicycle Therapeutics, Inc.、Cybrexa Therapeutics Inc.、Novartis AG、Oncopeptides AB 等。市場參與者透過各種策略(包括併購、合作、合作、融資和新產品發布),為市場成長做出了巨大貢獻,以保持市場競爭力。例如,2023 年 9 月,總部位於日本神奈川的生物製藥上市公司 PeptiDream Inc. 與羅氏集團旗下美國基因泰克公司簽訂了一項新的多目標合作和許可協議,旨在發現和開發新型大環肽-放射性同位素藥物綴合物。
Title: Global Peptide Drug Conjugates Market Size, Share & Trends Analysis Report by Type (Diagnostic and Therapeutic), and by Product (Melflufen, Lutetium, ANG1005, BT1718 and CBX-12),Forecast Period (2023-2030).
The global peptide drug conjugates market is anticipated to grow at a CAGR of 9.4% during the Forecast Period (2023-2030). The market is attributed to factors including the increasing prevalence of cancer and metabolic disorders, rising investments in the R&D of novel drugs, and technological advancements in drug development. According to the Globocan 2020, number of cancer cases were 50,550,287. Of which, the total number of new cases 19,292,789 around the globe.
The global peptide drug conjugates market is segmented on the type, and product. Based on the type, the market is sub-segmented into diagnostic and therapeutic. Based on the product, the market is sub-segmented into melflufen, lutetium, ANG1005, BT1718 and CBX-12. Among the type, the therapeutic sub-segment is anticipated to hold a considerable share of the market, owing to the emerging targeted therapeutic that present increased tumor penetration and selectivity.
Among the product, the melflufen sub-segment is expected to hold a considerable share of the global Peptide Drug Conjugates market. The segmental growth is attributed to the owing to increasing awareness about current treatment options, favorable reimbursement policies, the launch of Melflufen and rapid uptake of PDC drugs in cancer therapy., In February 2021, the FDA approved the first anticancer peptide-drug conjugate, melphalan flufenamide, or melflufen, for use in combination with dexamethasone. Based on the phase 2 HORIZON research, the product, developed by the Swedish biotech company Oncopeptides AB, received accelerated approval. In adult patients with refractory multiple myeloma, who have received at least 4 prior lines of therapy and whose disease is refractory to at least 1 proteasome inhibitor, 1 immunomodulatory agent, and 1 CD38-directed monoclonal antibody.
The global peptide drug conjugates market is further segmented based on geography including North America (the US, and Canada), Europe (UK, Italy, Spain, Germany, France, and the Rest of Europe), Asia-Pacific (India, China, Japan, South Korea, and Rest of Asia), and the Rest of the World (the Middle East & Africa, and Latin America). Among these, Asia-Pacific is anticipated to hold a prominent share of the market across the globe, owing to the rising investments to develop and commercialize new delivery systems.
Among all regions, the North America regions is anticipated to grow at a considerable CAGR over the forecast period. The major factors driving the North America market is the increasing number of cancer cases across the region is estimated to certainly impact the peptide drug conjugates market growth in upcoming years. According to the American Cancer Society (ACS), in 2022, around 1,918,030 new cancer cases and 609,360 cancer mortalities were reported in the US. As per the reports of Royal Society Publishing Organization, HPRP-A1-TAT, a hybrid peptide, can destroy the cell membrane to cause rapid leakage of cytoplasmic contents, and has a strong anti-cancer activity.
The major companies serving the global peptide drug conjugates market include: Angiochem Inc., Bicycle Therapeutics, Inc., Cybrexa Therapeutics Inc., Novartis AG, Oncopeptides AB, and others. The market players are considerably contributing to the market growth by the adoption of various strategies including mergers and acquisitions, partnerships, collaborations, funding, and new product launches, to stay competitive in the market. For instance, in September 2023, PeptiDream Inc., a public Kanagawa, Japan-based biopharmaceutical company entered into a new multi-target collaboration and license agreement with US based Genentech, a member of the Roche Group, targeted on the discovery and development of novel macrocyclic peptide-radioisotope drug conjugates.