市場調查報告書
商品編碼
1184285
重組蛋白全球市場規模、份額和行業趨勢分析報告:2022-2028 年各產品、最終用戶、應用和地區的展望和預測Global Recombinant Proteins Market Size, Share & Industry Trends Analysis Report By Product, By End User, By Application, By Regional Outlook and Forecast, 2022 - 2028 |
在預測期內,重組蛋白的全球市場規模預計將以 10.8% 的複合年增長率增長,到 2028 年將達到 26 億美元。
該業務的增長預計將受到肉芽腫病、血友病和硬化症等慢性病發病率增加的推動。 此外,重組蛋白產品的改進、對生物製劑和生物仿製藥的日益偏好以及其他原因都有助於行業擴張。 COVID-19 的爆發加劇了尋找 SARS-CoV2 病毒治療和診斷工具的競賽。
根據 Global Genes 的數據,全球有超過 4 億人患有罕見遺傳病。 這個數字突出了對治療、改善醫療保健環境和增加公眾對健康問題的了解的迫切需要。 藥物靶向機制的最新研究和知識對於生產藥物至關重要。
隊列計劃在多個地區創建了生物樣本庫,使研究人員能夠獲得高質量的樣本,這些樣本正在徹底改變治療工作。 這可能會導致更加強調識別各種疾病的生物標誌物。 例如,2022 年 8 月,FDA 批准 Ayvakit 用於治療晚期系統性肥大細胞增多症,這是一種罕見的血液疾病。
COVID-19 影響分析
對快速大規模開發 COVID-19 疫苗的需求,加上正在進行的商業製造活動,將對生物製品研究工作產生積極影響,從而推動行業擴大 COVID-19 大流行對蛋白質市場的擴張產生了有利影響。 鑑於 COVID 感染的傳播,可以開發結合不同佐劑和抗原亞基的重組蛋白疫苗,這些疫苗對 SARS-CoV-2 感染更有效,並且在中心很容易獲得。
市場增長因素
由於慢性病的增加,人們對定製藥物的興趣與日俱增
重組蛋白被認為是為數不多的治療慢性病的藥物之一,隨著慢性病的增多,對重組蛋白療法的需求也越來越大。 據 GLOBOCAN 估計,2020 年墨西哥將出現 195,499 例新癌症病例和 90,222 例癌症相關死亡病例。 一些生物技術,如疫苗、重組蛋白、細胞和基因療法,對於治療的個體化至關重要,因此需要納入個體化醫療的發展。
增加生物製品的研發
由於生物製劑研究和開發的增加,預計重組蛋白市場的需求將會增長。 由於研究週期長和法規滯後,研發行業傳統上需要大量資金。 研發支出佔全球支出的很大一部分。 各國政府認識到研發是國家發展、國際競爭力和公共利益的重要因素。 因此,研發資金和支出穩步增加。
市場約束
重組蛋白越來越便宜。
重組蛋白是使用實驗室培養的細胞製成的,這導致了它們的高成本。 據說佔製造成本 80% 的煉油也是一項主要支出。 價格侵蝕被定義為大量玩家進入特定市場,銷售沒有原創性的相同產品,並以價格合理但沒有創意的產品飽和市場。 價格侵蝕是指這些產品在市場上的價格不斷下降,從而減緩了市場擴張。
產品展望
按產品劃分,它分為生長因子和趨化因子、免疫反應蛋白、結構蛋白、膜蛋白、激□蛋白、調節蛋白、重組代謝□、粘附分子和受體以及其他重組蛋白。 到 2021 年,免疫反應蛋白預計將佔銷售額的很大一部分。 細胞因子是體內一組重要的蛋白質。 這些小蛋白質充當免疫系統的信使。 它充當免疫系統的通信網絡,並作為對威脅的反應而產生。 免疫系統細胞有時通過彼此直接接觸相互作用,但更常見的是通過分泌細胞因子,它們可以作用於附近或遠處的細胞。
應用展望
按應用分為藥物發現和市場開發、生物製藥生產、生物技術研究、學術研究、診斷和其他應用。 生物技術研究將在 2021 年佔據很大的收入份額。 重組蛋白有助於闡明生物的基本原理。 這些分子可用於定位和查明由特定基因編碼的蛋白質,以及其他基因在細胞信號傳導、代謝、生長、複製、死亡和翻譯中的作用。了解更多關於它們如何參與以下過程的信息、轉錄和蛋白質修飾。
最終用戶視角
基於最終用戶,重組蛋白市場細分為製藥和生物製藥行業、生物技術行業、學術研究機構、合同研究機構和其他最終用戶。 合同研究實驗室預計將在 2021 年佔市場收入的很大一部分。 研發行業對學術機構和公司之間的伙伴關係和合作的投資有所增加。 例如,輝瑞的治療創新中心 (CTI) 充當醫療保健系統利益相關者之間互動的論壇。
區域展望
按地區劃分,重組蛋白市場分為北美、歐洲、亞太地區和 LAMEA。 2021年重組蛋白的主要區域市場是北美。 慢性病和遺傳病的高患病率;研發資金;由於製藥業的大量存在以及分析儀器在藥物發現和研發中的應用,北美似乎在全球市場中佔有很大份額。
The Global Recombinant Proteins Market size is expected to reach $2.6 billion by 2028, rising at a market growth of 10.8% CAGR during the forecast period.
Recombinant proteins have a huge future in the study and development of cancer therapies. Examples of recombinant proteins used in cancer therapy research include growth factors, immunological checkpoints, and cell damage & oxidative stress proteins (preclinical stage). The utilization of recombinant proteins including immunological checkpoint, antibodies, and growth factors, for targeted purposes has risen as a result of a greater knowledge of neoplastic signalling cascades and the proteins involved in them.
Researchers utilise these proteins frequently to study how cancer signalling pathways and functions. Research uses recombinant immune checkpoints that directly target programmed death-1 (PD-1) and programmed death ligand-1 and 2 (PD-L1), including PD-1/PD-L1 Inhibitor 1 and PD-1/PD-L1 Inhibitor 2. Aside from that, proteins like CD40 Ligand/TRAP, CD226, and Human CellExp CTLA4/CD152 are often employed in studies on cancer therapy.
Growth in the business is predicted to be fueled by the increased incidence of chronic disorders such granulomatous disease, haemophilia, and sclerosis. Additionally, improved recombinant protein products, the growing preference for biologics and biosimilars, and other reasons all contribute to the industry's expansion. The race to discover cures and diagnostic tools for the SARS-CoV2 virus was fuelled by the COVID-19 epidemic.
With over 400 million people worldwide suffer from uncommon genetic illnesses, according to Global Genes. This figure demonstrates the urgent need for therapies, an improvement in healthcare environments, and increased public knowledge of health issues. A critical instrument for the creation of medicines is the requirement for cutting-edge research and knowledge of drug targeting mechanisms.
Cohort programmes have helped several regions create biobanks that give researchers access to high-quality samples that will revolutionise treatment efforts. This may lead to a greater emphasis on the identification of biomarkers for various illnesses. As an illustration, the FDA approved Ayvakit in August 2022 to address advanced systemic mastocytosis, a rare blood disorder.
COVID-19 Impact Analysis
The requirement for the COVID-19 vaccine to be developed quickly and on a large scale, as well as its ongoing commercial manufacturing activities, had a favourable effect on the development of biologics-based research initiatives and ultimately helped the industry's expansion. The COVID-19 pandemic had a favourable effect on the expansion of the proteins market. Recombinant protein vaccines may be developed with a combination of subunits of different adjuvants and antigens that will be more effective against SARS-CoV-2 infections and be readily available in the centre, it was suggested in light of the growth in COVID infection.
Market Growth Factors
Growing Emphasis On Customised Medicine Due To An Increase In The Prevalence Of Chronic Diseases
Recombinant proteins are one of the few recognised treatments for such conditions, and as chronic illnesses are on the rise, there is a significant demand for recombinant protein therapies. According to GLOBOCAN, there were estimated 195,499 new cancer cases and 90,222 cancer-related deaths in Mexico in 2020. Several biotechnologies, including vaccines, recombinant proteins, and cell and gene therapies, must be incorporated into the development of personalised medicine since they are essential to the personalization of care.
Increasing Biologics Research And Development
The market for recombinant proteins is anticipated to expand in demand due to the increased research and development on biologics. The R&D industry has traditionally required a lot of capital because of lengthy study periods and regulatory delays. Consumption on R&D accounts for a considerable share of global spending. Governments acknowledge R&D as a crucial factor in a nation's development, global competitiveness, and public good. R&D funding and spending have risen steadily as a result.
Market Restraining Factors
Recombinant proteins are getting cheaper.
Recombinant Proteins are made in labs using cells that have been grown, which contributes to their expensive price. Purification of these medications, which can make up as much as 80% of the manufacturing costs, is one of the major expenses. Price erosion is defined as when many players enter a particular market and sell identical products without any uniqueness, saturating the market with less creative and reasonably priced goods. Price erosion is the constant drop in the price of these products in a given market, which slows down market expansion.
Product Outlook
Based on Product, the market for recombinant proteins is classified into growth factors and chemokines, immune response proteins, structural proteins, membrane proteins, kinase proteins, regulatory proteins, recombinant metabolic enzymes, adhesion molecules and receptors, and other recombinant proteins. Immune response proteins are expected to command a sizable sales share in 2021. A crucial group of proteins in the body are cytokines. These little proteins act as immune system messengers. They serve as the immune system's network of communication and are created in reaction to a threat. Immune system cells can sometimes interact by touching one another directly, but more frequently, they do so via secreting cytokines, which can operate on other cells nearby or far away.
Application Outlook
Based on application, the market Drug Discovery & Development, Biopharmaceutical Production, Biotechnology Research, Academic Research Studies, Diagnostics, and Other Applications. The biotechnology research command a significant revenue share in 2021. Recombinant proteins aid in illuminating an organism's basic and underlying principles. These molecules can be used to identify and pinpoint the location of the protein that a particular gene encodes, as well as to learn more about how other genes are involved in processes such as cell signalling, metabolism, growth, replication, and death, as well as translation, transcription, and protein modification.
End User Outlook
Based on End User, the Recombinant Proteins Market is divided in pharmaceutical and biopharmaceutical industry, biotechnology industry, academic research institutes, contract research organisations, and other end users. Contract Research Organizations are expected to account for a sizable portion of market revenue in 2021. The R&D industry saw increased investments in regards to partnerships and collaborations between academic institutions and businesses. For instance, the Center for Therapeutic Innovation (CTI) at Pfizer serves as a forum for interaction among stakeholders in the healthcare system.
Regional Outlook
Based on geography, the Recombinant Proteins Market is classified into North America, Europe, Asia Pacific, and LAMEA. The leading regional market for recombinant proteins in 2021 was North America. The high prevalence of chronic and genetic diseases, the availability of funding for R&D, government initiatives for R&D in the pharmaceutical industry, the growing use of life science techniques in research and academia, the significant presence of major pharmaceutical and biotechnology organizations, and the application of analytical instruments in drug discovery and development are all factors that contribute to North America holding a significant share of the global market.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Bio-Techne Corporation, Thermo Fisher Scientific, Inc., Merck Group, Bio-Rad Laboratories, Inc., Abcam plc, Genscript Biotech Corporation, Miltenyi Biotec B.V. & Co. KG, Proteintech Group, Inc., BPS Bioscience, Inc., and RayBiotech Life, Inc.
Strategies Deployed in Recombinant Proteins Market
Nov-2022: Abcam comes into agreement with NanoString Technologies, Inc., a leading provider of life science tools for discovery and translational research. Through this agreement, Abcam RabMAb™ recombinant antibodies would be produced as part of the first 64-plex protein panel for NanoString's CosMx™ Spatial Molecular Imager (SMI). Additionally, this agreement would open the full capability of spatial biology and help enhance care for people with cancer.
2022-Jul: Bio-Rad Laboratories launched EconoFit Columns, a low-pressure prepacked chromatography column pack. The EconoFit columns are created for resin screening, enabling customers that are designing protein purification workflows to choose the optimal chemistry for various targets. The products offer run-to-run uniformity to support preparative scale purifications and method advancement for the latest target proteins, as well as to improve existing workflows.
Feb-2022: Abcam came into agreement with Twist Bioscience Corporation, a synthetic biology company. Under this agreement, Abcam would use a proprietary Twist VHH phage library for antibody development, discovery, and commercialization for research and diagnostic application. Moreover, Twist Bioscience grants Abcam the right to perform research and development activities utilizing Twist single domain (VHH) synthetic antibody library.
Jan-2022: Thermo Fisher Scientific Inc. completed the acquisition PeproTech, Inc., a leading developer, and manufacturer of recombinant proteins. Through this acquisition, PeproTech's recombinant proteins suite aligns with Thermo Fisher's cell culture media products and would allow Thermo Fisher to offer customers significant advantages through an integrated offering.
2021-Nov: Abcam partnered with Nautilus Biotechnology, Inc., a development-stage life sciences company. Under this partnership, Both companies would focus on the combined advancement of affinity binding reagents used on the Nautilus proteomic analysis system and would broaden in the upcoming time to the large-scale manufacturing and supply of reagents for production.
Mar-2021: Bio-Techne Corporation released Cultrex™ UltiMatrix, a hydrogel extracellular matrix that is beneficial for cultivating pluripotent stem cells and organoids in terms of performance and consistency. The product develops Matriz hydrogels that support the growth use of pluripotent stem and organoid cells for drug research, commercialize medicine, and regenerative medicine.
Nov-2020: Merck signed an agreement with Donghao Lansheng (Group) Co., Ltd., a large modern service industry. This agreement would drive a new process that helps the custom clearing of research material for analytical use and biomedical innovation, through this Merck would be able to process shipments with the technical dossier and fewer application needs.
Nov-2019: Abcam plc announced a partnership with BrickBio, a Tiger Gene suite company and have specialization in site-specific protein modification. Through this partnership, Abcam would have full rights to the platform for the formation of novel conjugation-ready recombinant products for the research equipment market and to produce the platform over its recombinant antibody and protein offering for diagnostic use.
Apr-2019: Bio-Techne Corporation Collaborated with Elpiscience BioPharma, a clinical-stage biopharmaceutical company. Through this collaboration, both companies aimed to advance anti-cancer therapeutics and boost the development of the latest biologics to meet the medical requirements in Oncology.
Apr-2018: Proteintech Group acquired HumanZyme, a manufacturer of recombinant human proteins. Through this acquisition, the company would strengthen its place as a manufacturer of antibodies, ELISA kits, and proteins.
Market Segments covered in the Report:
By Product
By End User
By Application
By Geography
Companies Profiled
Unique Offerings from KBV Research
List of Figures