市場調查報告書
商品編碼
1466564
抗體片段市場:按類型、抗體類型、應用分類 - 2024-2030 年全球預測Antibody Fragments Market by Type (F(ab) Fragments, F(ab')2 Fragments, Single Domain Antibody Fragments (sdAbs)), Antibody Type (Monoclonal, Polyclonal), Application - Global Forecast 2024-2030 |
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預計2023年抗體片段市場規模為77.2億美元,預計2024年將達到80.7億美元,2030年將達到104.2億美元,複合年成長率為4.36%。
抗體片段是抗體的一部分,可以與特定類型的抗原結合,抗原是體內引起免疫反應的外來物質。抗體片段通常衍生完整抗體,並透過酵素消化或基因工程技術開發。這個市場開拓的關鍵驅動力是擴大採用標靶治療來治療自體免疫疾病等慢性疾病。遺傳和生化技術的進步也為增強這些片段的生產和工程化鋪平了道路,從而推動了成長。研發資金的不斷增加和強大的醫療基礎設施(尤其是在已開發國家)促進了整體市場的成長。然而,生產和精製抗體片段的高成本可能會限制市場成長。新興市場的監管挑戰和缺乏認知也是潛在的成長阻礙因素。新的可能性包括使用抗體片段開發創新藥物並將其用於開拓的疾病領域。此外,新興市場製藥和生物技術工作的擴展和整合也為抗體片段市場的成長帶來了重大機會。
主要市場統計 | |
---|---|
基準年[2023] | 77.2億美元 |
預測年份 [2024] | 80.7億美元 |
預測年份 [2030] | 104.2億美元 |
複合年成長率(%) | 4.36% |
單域抗體 (sdAb) 由於其穩定性和靈活的結合而在應用中迅速普及。
F(ab) 片段是具有單一抗原結合位點 (Fab) 的小抗體片段。由於它沒有保守的 Fc 區,因此不能透過抗體依賴性細胞毒性來破壞細胞。應用於影像診斷、診斷藥物等。與 F(ab) 相比,F(ab')2 片段具有兩個抗原結合位點,使抗體能夠更牢固地與其標靶結合。與 F(ab)2 片段相比,F(ab')2 片段具有兩個抗原結合位點,可以更強地結合標靶。單域抗體 (sdAb) 以其高溶解度、熱穩定性和與酶活性位點結合的能力而聞名,在治療和研究中具有廣泛的用途。單鏈可變片段 (scFv) 具有與單株抗體類似的結合特異性。作為設計抗體衍生物的有效工具,它受到標靶藥物遞送和免疫治療的青睞。
抗體類型:單株抗體的使用由於其在標靶治療中的高特異性而不斷增加。
單株抗體 (MAb) 是由單一 B 細胞克隆產生的相同抗體。單株抗體對單一抗原決定簇具有特異性,具有高特異性、一致的品質和無限的供應。例子包括特定蛋白質的檢測和定量、腫瘤和自體免疫疾病等治療領域,以及細胞和組織的染色,在這些領域中,僅檢測感興趣的抗原很重要。多株抗體(PAb) 是體內不同 B 細胞克隆產生的抗體混合物,每種抗體識別抗原上的不同表位。其結果是產生一系列在某些條件下可能有益的反應。多株抗體是需要在檢測系統中提供強大訊號的研究的首選,例如蛋白質印跡、ELISA 和免疫組織化學。由於 PAb 在不同條件下可以結合多個表位,因此能夠耐受抗原構象的微小變化。可以提供比單株抗體更高的整體結合親和性。
應用 抗體片段在癌症治療的應用進展
抗體片段在癌症治療的應用被認為是癌症研究的突破。它們的小尺寸使它們能夠比完整抗體更有效地穿透並結合癌細胞。此外,它可以最大限度地減少對健康細胞造成附帶損害的風險,並提供更有針對性的治療方法。抗體片段在免疫力缺乏的治療中極為重要。抗體片段補償缺失或不足的抗體反應,並提高患者抵抗感染疾病的能力。它們還可以針對特定疾病生物標記進行設計,從而實現更個性化的治療。雖然癌症治療主要著重於針對性地清除癌細胞,免疫力缺乏使用抗體片段來增強人體的免疫反應。
區域洞察
由於持續的研究舉措為市場成長鋪平了道路,美洲在抗體片段市場中佔有重要地位。這些國家的購買行為很大程度上是由個人化醫療的出現所推動的,特別關注特異性疾病的應用。隨著私人和政府對下一代醫療保健技術的投資增加,預計將進一步成長。由於健康意識的提高和政府的公共衛生舉措,歐洲、中東和非洲 (EMEA) 是一個快速成長的抗體片段市場。這些地區與文明病呈上升趨勢,醫療保健領域需要創新的治療方法。歐盟國家和中東地區正在對診斷技術和研究進行大量投資,提供了廣泛的市場潛力。亞太地區是一個新興的醫療保健影響者和對抗體片段的需求不斷成長的地區。該領域不斷增加的研發投資顯示該地區市場成長前景廣闊。該地區的客戶行為揭示了對治療應用的傾向,許多製造商希望利用這一點,進一步推動該地區的市場成長。
FPNV定位矩陣
FPNV定位矩陣對於評估抗體片段市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可以對抗體片段市場供應商的現狀進行深入而深入的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4.競爭力評估與資訊:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況、製造能力等進行全面評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1. 抗體片段市場的市場規模與預測是多少?
2.抗體片段市場預測期內需要考慮投資的產品、細分市場、應用和領域有哪些?
3.抗體片段市場的技術趨勢和法規結構是什麼?
4.抗體片段市場主要廠商的市場佔有率為何?
5. 進入抗體片段市場的合適型態和策略手段是什麼?
[189 Pages Report] The Antibody Fragments Market size was estimated at USD 7.72 billion in 2023 and expected to reach USD 8.07 billion in 2024, at a CAGR 4.36% to reach USD 10.42 billion by 2030.
Antibody fragments refer to parts of antibodies capable of binding to specific types of antigens, the foreign substances in the body that induce an immune response. Antibody fragments are usually derivatives from whole antibodies and are developed through enzyme digestion or genetic engineering techniques. The primary driver of this market development is the increasing adoption of targeted therapies for treating chronic conditions, such as autoimmune diseases. Advancements in genetic and biochemical technologies have also paved the way for enhanced production and engineering of these fragments, boosting growth. A constant increase in R&D funding and robust healthcare infrastructure, especially in developed countries, contributed to overall market growth. However, the high costs of producing and purifying antibody fragments can restrict market growth. Regulatory challenges and lack of awareness in emerging markets also pose potential growth restrictions. New avenues for potential opportunities include the development of innovative drugs using antibody fragments and their usage in untapped disease areas. Additionally, the expansion and consolidation of pharmaceutical and biotechnological efforts in emerging markets also present significant opportunities for growth in the antibody fragments market.
KEY MARKET STATISTICS | |
---|---|
Base Year [2023] | USD 7.72 billion |
Estimated Year [2024] | USD 8.07 billion |
Forecast Year [2030] | USD 10.42 billion |
CAGR (%) | 4.36% |
Type: Burgeoning usage of single domain antibody fragments (sdAbs) in terms of applications due to their stability and flexibility in binding
F(ab) Fragments are small antibody fragments that contain one antigen-binding (Fab) site. It does not present the conserved Fc region; therefore, it cannot destroy cells through antibody-dependent cellular cytotoxicity. Applications include imaging and diagnostics. F(ab')2 Fragments, compared to F(ab), contain two antigen-combining sites, enabling the antibody to bind more vigorously to its targets. It is appreciated for allowing a more concentrated tracking accuracy in in-vivo imaging. Single domain antibody fragments (sdAbs) are known for their high solubility, thermal stability, and ability to bind to enzyme active sites, making their uses variegated in therapeutics and undergoing research. Single-chain variable fragments (scFvs) have binding specificity similar to monoclonal antibodies. They are preferred for targeted drug delivery and immunotherapy as efficient tools for the design of antibody derivatives.
Antibody Type: Proliferating utilization of monoclonal antibodies owing to their high specificity in targeted therapeutics
Monoclonal antibodies(MAbs) are identical antibodies made by a single B-cell clone. They are specific for a single antigenic determinant, resulting in high specificity, consistently high quality, and unlimited supply. On a needs-based perspective, monoclonal antibodies are preferred in situations necessitating a high degree of specificity, such as in assays for detection and quantification of specific proteins, therapeutic areas such as oncology, autoimmune disorders, and in cell and tissue staining where it's critical to detect only the antigen of interest. Polyclonal antibodies (PAbs) are a mix of antibodies produced by different B cell clones in the body, each recognizing a different epitope of an antigen. This results in a broad-spectrum response that can be beneficial under certain conditions. Polyclonal antibodies are preferred in research requiring robust signals in detection systems such as Western blot, ELISA, or immunohistochemistry. Their capacity to bind multiple epitopes under varying conditions makes the PAbs more forgiving to slight changes in antigen conformation. It can offer a higher overall binding affinity than monoclonal antibodies.
Application: Evolving application of antibody fragments in cancer therapy
Antibody fragments in cancer therapy have been regarded as a breakthrough in oncology research. Their small size makes them penetrate and bind to cancer cells more efficiently than whole antibodies. Moreover, they minimize the risk of collateral damage to healthy cells, offering a more targeted treatment approach. Antibody fragments have been crucial in the treatment of immunodeficiencies. They help replace missing or inadequate antibody responses, improving the patient's ability to fight off infections. They offer more personalized treatment owing to their ability to be engineered to target specific disease biomarkers. Cancer treatment mainly focuses on the targeted elimination of cancer cells, whereas, in immunodeficiencies, antibody fragments are employed to boost the body's immune response.
Regional Insights
The Americas has a significant landscape in the antibody fragments market owing to ongoing research initiatives that pave the way for the market's growth. The purchasing behavior in these countries is predominantly driven by the advent of personalized medicine, with a notable focus on disease-specific applications. With the rising private and government entities' investments in next-generation healthcare technologies, further growth is anticipated. Europe, the Middle East, and Africa (EMEA) exhibit a burgeoning market for antibody fragments, driven by a rise in health consciousness and governmental initiatives for public health. The increase in lifestyle diseases in these regions has necessitated innovative therapeutics in the healthcare sector. EU countries and the Middle East are experiencing heavy investments in diagnostic technologies and research, thus promising market potential. The Asia Pacific region, home to emerging healthcare influencers, is witnessing a growing demand for antibody fragments. Increased investments in research & development in the field indicate a promising market growth in this region. The customer behavior in this region reveals an inclination towards therapeutic applications, which many manufacturers are looking to capitalize on, further increasing the market growth in the area.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Antibody Fragments Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Antibody Fragments Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Antibody Fragments Market, highlighting leading vendors and their innovative profiles. These include AbbVie Inc., Adaptimmune Therapeutics PLC, Aenova Group GmbH, Almac Group, Amgen Inc., Antikor Biopharma, Astellas Pharma Inc., Baxter International Inc., Biogen Inc., Bristol-Myers Squibb Company, Confo Therapeutics, Dyne Therapeutics, Eli Lilly and Company, Evonik Industries AG, F. Hoffmann-La Roche Ltd., Genentech, Inc., Gilde Healthcare, Johnson & Johnson Services, Inc., MoonLake Immunotherapeutics AG, Novartis AG, Numab AG, Pfizer Inc., Sanofi S.A., Takeda Pharmaceutical Company Limited, and Thermo Fisher Scientific Inc..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Antibody Fragments Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Antibody Fragments Market?
3. What are the technology trends and regulatory frameworks in the Antibody Fragments Market?
4. What is the market share of the leading vendors in the Antibody Fragments Market?
5. Which modes and strategic moves are suitable for entering the Antibody Fragments Market?