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市場調查報告書
商品編碼
1820223
2025 年至 2033 年抗生素市場規模、佔有率、趨勢及預測(依作用機轉、藥物類別、活性範圍、給藥途徑、最終用戶及地區分類)Antibiotics Market Size, Share, Trends and Forecast by Action Mechanism, Drug Class, Spectrum of Activity, Route of Administration, End User, and Region, 2025-2033 |
2024年,全球抗生素市場規模達533億美元。預計到2033年,該市場規模將達到738億美元,2025-2033年期間的複合年成長率為3.3%。亞太地區目前佔據市場主導地位,2024年將佔據約44%的市場。肺炎、結核病和其他傳染病病例的增加推動了市場的發展。人們對抗生素抗藥性的日益擔憂正推動著新型、更有效的抗生素療法的發展。此外,發展中地區醫療保健服務的不斷擴大也支持了抗生素消費量的增加。此外,生物技術和藥物研發技術的持續進步也是擴大抗生素市場佔有率的主要因素之一。
目前,全球人口中慢性病的盛行率不斷上升,推動了市場的成長。此外,抗生素透過線上實體門市的廣泛供應以及對外用抗生素需求的增加,也推動了產品需求的成長。抗生素有助於降低患者手術傷口感染的風險,這增強了全球對抗生素的需求。為了牲畜的健康和福祉,抗生素的使用量不斷增加,也推動了市場的成長。此外,消費者對預防性醫療保健措施的意識不斷增強,以及老齡化人口需求的成長,也支持了抗生素市場的成長。
美國抗生素市場正經歷利潤豐厚的成長,這得益於持續的細菌感染治療需求以及日益嚴重的抗生素抗藥性問題。科學研究投入和政府支持的措施正在推動更有效治療方法的發展。一個顯著的例子是美國食品藥物管理局 (FDA) 於 2023 年 4 月批准的 Zevtera(注射頭孢比普利美多卡利鈉),該藥物旨在治療金黃色葡萄球菌血流感染(菌血症),包括右側感染性心內膜炎和急性細菌性皮膚感染。
傳染病發生率上升
在全球範圍內,肺炎、肺結核、泌尿道感染 (UTI)、胃腸道感染和血液敗血症等傳染病的發生率正在上升,而由於衛生條件差,人們患這些疾病的幾率也隨之上升。這加劇了細菌感染的傳播。每 25 名女性中就有 10 名,每 25 名男性中就有 3 名在一生中的某個階段患有泌尿道感染。我們需要更強效的抗生素來幫助治療這些感染。抗生素專門用於靶向和消除細菌感染。它們能有效殺死體內細菌並促進癒合。此外,抗生素也需要在醫療專業人員的指導下使用,以最佳化患者的預後。
抗菌素抗藥性(AMR)的發生率不斷上升
在全球範圍內,抗菌素抗藥性 (AMR) 的發生率呈上升趨勢,這推動了抗生素市場的發展。當細菌、病毒、寄生蟲或真菌進化並對用於治療它們的藥物產生抗藥性時,就會發生 AMR。它會降低抗生素的有效性,導致感染持續時間更長、病情更嚴重,增加醫療成本,並導致個人死亡率高。 2019 年,細菌抗菌素抗藥性 (AMR) 與全球 127 萬人死亡直接相關。抗生素的過度使用和濫用導致抗藥性細菌的產生,從而降低傳統抗生素的療效。此外,抗甲氧西林金黃色葡萄球菌 (MRSA) 和耐碳青黴烯腸桿菌科細菌 (CRE) 等多重抗藥性菌株更為常見。這需要銷售和開發先進的抗生素,從而促進市場成長。
抗生素技術進步
生物技術、分子生物學和藥物發現技術的創新正在幫助提高抗生素開發的效率和有效性。這反過來又增強了抗生素市場的前景。基因組學和高通量篩選使得識別潛在的藥物標靶和篩選大型化合物庫成為可能。許多公司正在投資這項技術。例如,2021 年 1 月,輝瑞宣布根據輝瑞突破性成長計畫 (PBGI) 向四家臨床階段生技公司投資 1.2 億美元。該合作旨在根據輝瑞未來的戰略利益推進有前景的臨床開發項目。電腦輔助藥物設計還可以預測藥物療效和最佳化抗生素候選物。這些技術進步簡化了抗生素發現過程,與傳統方法相比,減少了時間和成本。此外,快速病原體鑑定和敏感性測試等診斷技術的進步有助於選擇合適的抗生素以改善患者預後。
疾病負擔、抗藥性和地區差異導致需求上升
由於全球健康壓力日益增加,市場正在穩步成長。傳染病的發生率不斷上升,尤其是在中低收入國家,這推動了對廣譜抗生素的需求增加。產業報告顯示,2023年記錄了約820萬例新發結核病病例,較2022年的750萬例增加。呼吸道感染、泌尿道感染和胃腸道疾病仍然特別常見,促使全球醫療保健系統依賴抗生素作為第一線治療。同時,全球範圍內的抗生素抗藥性正在加劇,降低了舊療法的有效性,並迫使人們開發新的藥物類別。第一線抗生素的抗藥性增加,導致治療失敗和住院時間延長。這促使公共和私營部門對新型化合物和改進診斷方法進行投資。此外,抗生素使用和取得的地理分佈差異很大。高收入國家強調監測和管理,而許多中低收入地區則面臨獲取受限、品質不穩定和濫用的問題。這種不平衡增加了全球市場政策和供應鏈策略的複雜性。
The global antibiotics market size was valued at USD 53.3 Billion in 2024. The market is projected to reach USD 73.8 Billion by 2033, exhibiting a CAGR of 3.3% during 2025-2033. Asia Pacific currently dominates the market, holding a significant market share of around 44% in 2024. The market is fueled by the increasing cases of pneumonia, tuberculosis, and other infectious diseases among individuals. The increasing concerns over antimicrobial resistance are driving the development of new and more effective antibiotic therapies. Also, expanding healthcare access in developing regions is supporting greater antibiotic consumption. In addition to this, continual technological advancements in biotechnology and drug discovery techniques are some of the major factors augmenting the antibiotics market share.
Currently, the increasing prevalence of chronic diseases in the global population is contributing to the market growth. Moreover, the widespread availability of antibiotics through online and offline stores and increased demand for topical antibiotics are boosting the product demand. Antibiotics help reduce the risk of infection in the surgical wound area for individuals. This has strengthened the global demand for antibiotics. Rising employment of antibiotics for the health and welfare of livestock animals is also fueling the market growth. In addition, the increased consumer awareness of preventative health care measures and growing demand in aging population are supporting the antibiotics market growth.
The antibiotics market in the United States is witnessing lucrative growth, fueled by the ongoing need to treat bacterial infections and the growing issue of antibiotic resistance. Investments in research and government-backed initiatives are encouraging the development of more effective treatments. A notable example is the FDA's approval in April 2023 of Zevtera (ceftobiprole medocaril sodium for injection), which is designed to treat Staphylococcus aureus bloodstream infections (bacteremia), including right-sided infective endocarditis and acute bacterial skin infections.
Rising Incidence of Infectious Diseases
Worldwide, the incidence of infectious diseases such as pneumonia, tuberculosis, urinary tract infections (UTI), gastrointestinal infections and sepsis in the bloodstream is increasing among the population and people suffer more from these diseases because of inadequate sanitation. This contributes to the spread of bacterial infections. 10 out of 25 women and 3 out of 25 men have a urinary tract infection at some point in their lives. More powerful antibiotics are needed to help treat these infections. Antibiotics are specifically designed to target and eliminate bacterial infections. They effectively kill bacteria in the body and promote healing. Antibiotics are also used under the guidance of a health professional to optimize patient outcomes.
Increasing Occurrence of Antimicrobial Resistance (AMR)
There is a rise in the occurrence of antimicrobial resistance (AMR) across the globe, which is driving the antibiotics market. AMR occurs when bacteria, viruses, parasites, or fungi evolve and become resistant to the drugs used to treat them. It reduces the effectiveness of antibiotics and causes longer and more severe infections, increased healthcare costs, and high mortality rates among individuals. In 2019, bacterial antimicrobial resistance (AMR) was directly linked to 1.27 million deaths worldwide. Overuse and misuse of antibiotics are contributing to the development of drug-resistant bacteria, which makes traditional antibiotics less effective. In addition, multidrug-resistant strains, such as Methicillin-resistant Staphylococcus aureus (MRSA) and Carbapenem-resistant Enterobacteriaceae (CRE), are more prevalent. This necessitates the sales and development of advanced antibiotics, thereby contributing to the market growth.
Technological Advancements in Antibiotics
Innovations in biotechnology, molecular biology, and drug discovery techniques are helping to improve the efficiency and effectiveness of antibiotic development. This, in turn, is enhancing the antibiotics market outlook. Genomics and high-throughput screening enable the identification of potential drug targets and the screening of large compound libraries. Many companies are investing in the technology. For example, in January 2021, Pfizer Inc. announced a $120 million investment in four clinical-stage biotechnology companies under the Pfizer Breakthrough Growth Initiative (PBGI). The partnership aims to advance promising clinical development programs in line with Pfizer's future strategic interests. Computer-aided drug design also allows for predicting drug efficacy and optimizing antibiotic candidates. These technological advances have streamlined the antibiotic discovery process and reduce the time and costs compared to traditional methods. In addition, advances in diagnostic techniques, such as rapid pathogen identification and sensitivity testing, help in choosing the right antibiotic to improve patient outcomes.
Rising Demand due to Disease Burden, Resistance, and Regional Disparities
The market is experiencing steady growth due to increasing global health pressures. The rising prevalence of infectious diseases, particularly in low- and middle-income countries, is driving higher demand for broad-spectrum antibiotics. Industry reports indicate that approximately 8.2 million new tuberculosis cases were recorded in 2023, reflecting an increase from 7.5 million cases in 2022. Respiratory infections, urinary tract infections, and gastrointestinal disorders remain especially common, prompting healthcare systems worldwide to rely on antibiotics as frontline therapy. Concurrently, antimicrobial resistance is intensifying worldwide, reducing the effectiveness of older treatments and forcing the development of new drug classes. Resistance to first-line antibiotics has increased, leading to treatment failures and longer hospital stays. This has spurred public and private sector investments in novel compounds and improved diagnostics. Moreover, the geographic distribution of antibiotic usage and access varies significantly. High-income countries emphasize surveillance and stewardship, while many low- and middle-income regions face limited access, inconsistent quality, and misuse. This imbalance adds complexity to policy and supply chain strategies across the global market.
Cell wall synthesis inhibitors action mechanism is the largest action mechanism in 2024, holding around 52% market share. Cell wall synthesis inhibitors is a class of antibiotics that target the bacterial cell wall. These antibiotics interfere with the process of cell wall synthesis, which causes cell wall damage and eventual bacterial death. In addition, penicillin, cephalosporins, and carbapenems are some of the cell wall synthesis inhibitors. They work by inhibiting enzymes called penicillin-binding proteins (PBPs) that are involved in the cross-linking of peptidoglycan chains. Moreover, cell wall synthesis inhibitors are particularly effective against gram-positive bacteria due to their thicker peptidoglycan layer, which provides a greater target for disruption.
Penicillin leads the market with around 26% market share in 2024. As per antibiotics market report segmentation, Penicillin is a widely used class of antibiotics that belongs to the beta-lactam drug class. It works by inhibiting the synthesis of bacterial cell walls that causes cell wall damage and bacterial death. It is considered an essential medicine and is widely available as generic drugs. Apart from this, it is increasingly used in various healthcare settings, such as hospitals, clinics, and outpatient settings. In addition, the rising utilization of penicillin, as it is effective against various bacterial infections, is contributing to the growth of the market.
Broad-spectrum antibiotics segment leads the market with around 70% market share in 2024. Broad-spectrum antibiotics are a class of antibiotics that exhibit activity against a wide range of bacteria, such as gram-positive and gram-negative bacteria. In line with this, the rising adoption of broader spectrum antibiotics, as they are effective against a broader range of microorganisms compared to narrow-spectrum antibiotics, is bolstering the growth of the market. Apart from this, broad-spectrum antibiotics assist in treating infections when the causative bacteria are unknown or when the infection involves multiple bacterial species. The appropriate use of broad-spectrum antibiotics minimizes the risks of infections in the body.
Parenteral leads the market with over 68% market share in 2024. Parenteral antibiotics are administered via routes other than the digestive tract, such as intravenous (IV), intramuscular (IM), or subcutaneous (SC) routes. These routes allow for direct delivery of the medication into the bloodstream or deep tissues, bypassing the gastrointestinal system. In addition, parenteral antibiotics provide rapid and predictable drug absorption and immediate therapeutic effect. They are also suitable for patients with compromised gastrointestinal function. Apart from this, it allows for accurate dosing and is particularly beneficial in cases where high drug concentrations are needed or when oral administration is not possible.
Hospitals leads the market with around 60% market share in 2024. Antibiotics are widely consumed in hospitals due to the increased number of patients staying in this healthcare setting. Antibiotics are administered to patients admitted with severe infections. They are also administered before surgical procedures to reduce the risk of bacterial contamination. In line with this, the rising utilization of antibiotics among individual post-surgical prophylaxis is contributing to the growth of the market. Apart from this, the increasing consumption of antibiotics due to the rising risk of multidrug-resistant infections in hospitals is supporting the growth of the market.
In 2024, Asia-Pacific accounted for the largest market share of around 44%. The growing incidence of bacterial infections to poor sanitation is contributing to the growth of the market in the Asia Pacific region. Apart from this, the increasing demand for advanced antibiotics that can effectively combat multidrug-resistant bacteria is supporting the growth of the market. Furthermore, the presence of a large number of generic drug manufacturers is propelling the growth of the market in the region.
The North America antibiotics market is driven by the increasing incidence of infectious diseases, particularly respiratory infections, and urinary tract infections, as these conditions necessitate effective antibiotic treatments to combat rising bacterial resistance. Additionally, the aging population in the region contributes to heightened demand for antibiotics, as older adults are more susceptible to infections. Advances in antibiotic development, including novel formulations and combination therapies, are also critical in addressing antibiotic resistance challenges. Furthermore, strategic collaborations among pharmaceutical companies and increased investment in research and development are enhancing the pipeline of new antibiotics, ensuring the market remains responsive to evolving health needs.
United States accrued a market share of around 86% in the North America market in 2024. The increased incidence of bacterial illnesses, improvements in healthcare facilities, and significant R&D expenditures are the main factors propelling the U.S. antibiotics industry. Urinary tract infections and respiratory tract infections continued to be among the most frequently treated illnesses in 2023, which increased the need for a wide range of antibiotics. The market is greatly influenced by the aging population, which is expected to reach more than 78 million by 2040 and more than 88 million by 2060. This is because older people are more prone to illnesses. Also, one of the significant antibiotics market trends is the rise of strains of bacteria that are resistant to antibiotics, like MRSA, which is increasing the demand for next-generation antibiotics and sparked innovation in the pharmaceutical industry.
Research on new antibiotic classes and quick diagnostics are supported by government programs to address antimicrobial resistance (AMR), such as the National Action Plan for Combating Antibiotic-Resistant Bacteria. Additionally, market expansion is driven by the FDA's accelerated approval processes for important medicines and the robust presence of major pharmaceutical companies in the United States. Demand is being further fueled by healthcare facilities implementing stricter antibiotic regimens in response to an increase in hospital-acquired infections (HAIs). The U.S. market for antibiotics is expanding despite issues with overuse and resistance, owing to strong healthcare spending and innovation.
The growing cases of infectious diseases and the numerous government programs designed to fight antibiotic resistance are the main factors affecting the antibiotics market in Europe. According to the World Health Organization (WHO), Europe uses a diverse range of antibiotics and has a high rate of resistant bacterial strains, including Klebsiella pneumonia and E. coli. As a result, the players are investing in the creation of novel antibiotics and stewardship initiatives to maximize their use.
Leading countries in this sector include Germany, France, and the United Kingdom, bolstered by their sophisticated healthcare systems and proactive AMR regulations. Additionally, the EMA has expedited the approval procedures for antibiotics that fulfill unmet medical requirements. The increase of outpatient care services and the increasing use of quick diagnostic techniques for bacterial infections are driving the market demand further.
The high incidence of infectious diseases, rising healthcare costs, and growing awareness of contemporary treatments are all contributing to the Asia-Pacific antibiotics market's rapid expansion. Antibiotic demand is fueled by the high incidence of bacterial illnesses, such as pneumonia and tuberculosis, in nations like China, Indonesia, and India. According to time-series research, a total of 16,290 million doses of antibiotics were sold in India in 2020, which is slightly less than the amount in 2018 and 2019. Apart from this, the antibiotics market worth is further increased by the expanding middle class and better access to healthcare services in emerging markets.
The region's governments are tackling issues such as antibiotic resistance by supporting antibiotic stewardship initiatives and providing funds for research into novel medication classes. As significant producers of antibiotics, China and India also gain from export prospects. Additionally, the use of telemedicine platforms is expanding the availability of antibiotic treatments in remote locations.
The incidence of infectious disorders, such as gastrointestinal and respiratory infections, is propelling the Latin American market growth. Advanced antibiotics are being adopted by nations like Brazil and Mexico to fight infections that are worsened by inadequate access to healthcare and poor sanitation. The industry is expanding owing to government programs like vaccination campaigns that use preventative antibiotics and investments in healthcare infrastructure. Furthermore, the region's expanding pharmaceutical sector and collaborations with international pharmaceutical companies are opportunistic for the market growth.
The high incidence of infectious diseases, including respiratory infections, malaria, and tuberculosis, has an impact on the demand for antibiotics. Antibiotics are becoming more widely available in the Middle East due to the investments made in healthcare modernization by nations like Saudi Arabia and the United Arab Emirates. International agencies like UNICEF and WHO are assisting antibiotic supply chains in Africa to address healthcare issues. While government programs are encouraging local production to lessen reliance on imports, awareness campaigns and measures to combat antibiotic resistance are gradually improving usage patterns.
Key players in the industry are investing in research and development (R&D) activities to discover and develop new antibiotics and focus on antibiotic resistance, expanding the spectrum of activity, and improving the efficacy and safety profiles of antibiotics. Apart from this, they are engaging in collaboration with research institutions, academic organizations, and government bodies to leverage their expertise and address the challenges associated with antibiotic development, such as high costs and regulatory compliances. Moreover, antibiotic companies are actively promoting antibiotic stewardship programs that encourage responsible and appropriate use of antibiotics to avoid overdosage and misuse. According to antibiotics market research report, companies are increasingly conducting clinical trials and adhering to safety and efficacy standards to obtain regulatory approvals for their antibiotics.