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市場調查報告書
商品編碼
1800791
預裝色譜管市場報告(按類型、技術、應用、最終用途和地區)2025-2033Prepacked Chromatography Columns Market Report by Type, Technique, Application, End-Use, and Region 2025-2033 |
2024年,全球預載層析柱市場規模達22億美元。展望未來, IMARC Group預計到2033年,該市場規模將達到39億美元,2025-2033年期間的複合年成長率(CAGR)為6.3%。各種慢性疾病的發生率不斷上升,疾病管理對生物製藥的需求不斷成長,以及各行各業對層析柱應用的不斷增加,是推動市場成長的主要因素。
生物製藥需求增加
癌症、糖尿病、心血管疾病和自體免疫疾病等各種慢性疾病的盛行率不斷上升,推動著市場的成長。再加上對疾病管理用生物製藥的需求不斷成長,這些因素共同促進了市場的成長。根據美國國立衛生研究院 (NIH) 的數據,預計 2022 年印度癌症發生率為 14,61,427 例(粗發病率:每 10 萬人中有 100.4 例)。在兒童 (0-14 歲) 癌症中,淋巴球白血病(男孩:29.2%,女孩:24.2%)是主要發病部位。預計 2025 年癌症發生率將比 2020 年增加 12.8%。例如,IDF 糖尿病圖集(2021 年)報告稱,10.5% 的成年人口(20-79 歲)患有糖尿病,其中近一半的人不知道自己患有糖尿病。 IDF 預測顯示,到 2045 年,每八名成年人中就有一人患有糖尿病,約 7.83 億人,增幅達 46%。這將對預裝層析柱市場統計數據產生重大影響。
色譜技術的重大進步
色譜技術的不斷進步也推動著市場的發展。例如,包括高效液相層析 (HPLC) 和親和色譜在內的色譜技術的持續創新正在提高分離的效率、速度和解析度。色譜法在環境檢測中的廣泛應用正在影響市場的成長。例如,2023 年 6 月,安捷倫科技公司宣布推出兩款新型液相層析質譜系統 (LCMS):Agilent 6495D LC/TQ 和 Agilent Revident LC/Q-TQF。為了提升 Revident LC/Q-TQF 的高階效能,安捷倫也宣布推出全新的 Agilent MassHunter Explorer Profiling 軟體和 Agilent ChemVistra 庫管理器軟體。預計這將推動未來幾年預裝色譜柱市場的成長。
生物加工和一次性技術日益受到重視
生物製藥和生物技術行業日益關注一次性技術,以簡化生產流程並降低交叉污染風險,這促進了市場的成長。一次性預包裝柱無需批次間的清潔和驗證步驟,從而最佳化了寶貴的生產時間,從而提高了生產效率和成本效益。例如,2023年9月,專注於生物製程技術領導地位的生命科學公司Repligen Corporation宣布已達成最終協議,收購位於瑞典默恩達爾的私人控股公司Metenova AB(簡稱Metenova)。 Metenova預計在2023會計年度實現2,400萬至2,500萬美元的收入,這主要得益於其磁力混合和傳動系統技術的成功,這些技術已被全球生物製藥公司和合約開發與生產組織(CDMO)廣泛應用。該公司近期推出MixOne平台,進軍一次性混合市場,並充分利用其現有不鏽鋼(重複使用)產品線的成功經驗。
>1000 ML 佔據大部分市場佔有率
不同行業對大尺寸色譜柱的偏好日益成長,這推動了該細分市場的發展。 >1000 毫升預裝柱通常用於純化生物分子,例如單株抗體、蛋白質和疫苗。它們有助於實現高容量層析分離,確保生產出純度高、品質優良的生物製藥產品。此外,食品和飲料 (F&B) 製造商使用>1000 毫升預裝柱進行風味提取、品質控制以及糖、氨基酸和著色劑等成分的分離等任務。這些色譜柱有助於實現穩定的產品品質並符合食品安全法規。在化學研發 (R&D) 領域,這些色譜管柱對於化合物的合成和純化至關重要。研究人員可以有效地擴大色譜流程,節省時間和資源,同時確保產品純度。
離子交換層析法佔大部分市場佔有率
離子交換層析法用途廣泛,可應用於多種生物分子,包括蛋白質、核酸和其他帶電分子。這種適應性使其適用於各種研究和工業應用。此外,它還能根據待分離分子的電荷提供優異的選擇性。透過使用具有不同官能基的離子交換樹脂,研究人員可以從複雜混合物中有效地分離和純化目標分子。此外,它還能提供高解析度分離,從而能夠分離電荷性質不同的近緣物種。此外,它易於規模化生產,適用於生物製藥、食品加工和其他行業的大規模純化製程。
樣品製備佔據最大的市場佔有率
樣品製備是色譜分析的基本前提,推動了色譜分析市場的成長。它涉及從複雜樣品中提取、淨化和濃縮目標分子,確保只有相關化合物到達色譜柱。樣品製備的品質直接影響後續色譜分析的準確性和靈敏度,因此至關重要。此外,包括製藥、生物技術、食品飲料、環境監測和醫療保健在內的眾多行業都嚴重依賴色譜分析進行品質控制、研究和產品開發。此外,高效液相層析 (HPLC) 和質譜 (MS) 等分析技術的持續發展,要求樣品製備方法能夠滿足不斷變化的需求。
製藥和生物技術公司佔據最大的市場佔有率
製藥和生物技術公司必須遵守嚴格的監管要求,以確保其產品的安全性和有效性,這進一步推動了該細分市場的快速成長。色譜法是一種可靠且標準化的化合物表徵和純化方法,預裝管柱是實現合規性和保持生產一致性的理想選擇。此外,包括單株抗體和基因療法在內的生物製藥領域的不斷進步,也導致了針對這些複雜分子的專用色譜柱的需求不斷成長。此外,這些產業在藥物開發、生產和品質控制的各個階段都依賴對蛋白質、抗體和核酸等生物分子進行精確且高效的分離和純化。預裝色譜管柱提供了即用型解決方案,可顯著簡化這些流程,從而降低時間和人工成本。
北美引領市場,佔據最大的預裝層析柱市場佔有率
該報告還對所有主要區域市場進行了全面分析,包括北美(美國和加拿大);歐洲(德國、法國、英國、義大利、西班牙、俄羅斯等);亞太地區(中國、日本、印度、韓國、澳洲、印尼等);拉丁美洲(巴西、墨西哥等);以及中東和非洲。報告指出,北美是預裝層析柱最大的區域市場。
北美擁有眾多從事藥物發現、開發和生產的製藥和生物技術公司,這推動了市場的成長。此外,北美的製藥和生物技術產業受到美國食品藥物管理局 (FDA) 和加拿大衛生部製定的嚴格監管標準的約束。除此之外,色譜柱製造業的幾家主要參與者的總部或在北美擁有重要的業務。關鍵產業參與者的集中促進了競爭、創新和廣泛的產品供應。此外,該地區擁有先進的醫療保健基礎設施,包括尖端的診斷實驗室和醫療保健設施。色譜法廣泛應用於臨床診斷和研究,進一步刺激了對預裝柱的需求。例如,2024 年 2 月,島津製作所從 Activated Research Company, LLC(美國明尼蘇達州 ARC)收購了氣相層析 (GC) 催化微反應業務。
(請注意,這只是關鍵參與者的部分列表,完整列表在報告中提供。)
The global prepacked chromatography columns market size reached USD 2.2 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 3.9 Billion by 2033, exhibiting a growth rate (CAGR) of 6.3% during 2025-2033. The growing prevalence of various chronic diseases, the rising demand for biopharmaceuticals for disease management, and increasing utilization of chromatography across various industries are some of the major factors propelling the growth of the market.
Increased Demand for Biopharmaceuticals
The rising prevalence of various chronic diseases including cancer, diabetes, cardiovascular disorders, and autoimmune conditions is driving the growth of the market. This, coupled with the escalating demand for biopharmaceuticals for disease management is strengthening the growth of the market. According to NIH, the estimated number of incident cases of cancer in India for the year 2022 was found to be 14,61,427 (crude rate:100.4 per 100000). Among the childhood (0-14 yr) cancers, lymphoid leukemia (boys: 29.2% and girls: 24.2%) was the leading site. The incidence of cancer cases is estimated to increase by 12.8% in 2025 as compared to 2020. For instance, IDF Diabetes Atlas (2021) reports that 10.5% of the adult population (20-79 years) has diabetes, with almost half unaware that they are living with the condition. By 2045, IDF projections show that one in eight adults approximately 783 million, will be living with diabetes an increase of 46%. This is infleuncing the prepacked chromatography columns market statistics significantly.
Significant Technological Advancement in Chromatography
The market is also driven by continuous advancements in chromatography technology. For instance, ongoing innovations in chromatographic techniques including high-performance liquid chromatography (HPLC) and affinity chromatography are improving the efficiency, speed, and resolution of separation. The widespread adoption of chromatography in environmental testing is influencing the growth of the market. For instance, in June 2023, Agilent Technologies Inc. announced two new liquid chromatography-mass spectrometry systems (LCMS), the Agilent 6495D LC/TQ and the Agilent Revident LC/Q-TQF. Facilitating the high-end performance of the Revident LC/Q-TQF, Agilent is also announcing the new Agilent MassHunter Explorer Profiling software and the new Agilent ChemVistra library manager software. This is expected to fuel the prepacked chromatography columns market forecast over the coming years.
Rising Emphasis on Bioprocessing and Single-Use Technologies
The increasing focus of biopharmaceutical and biotechnology industries towards single-use technologies to streamline production and reduce cross-contamination risk is contributing to the growth of the market. Single-use prepackaged columns optimize the use of valuable production time by eliminating the need for cleaning and validation steps between batches which leads to more efficient and cost-effective manufacturing. For instance, in September 2023, Repligen Corporation, a life sciences company focused on bioprocessing technology leadership, announced that it has entered into a definitive agreement to acquire privately held Metenova AB (Metenova) of Molndal, Sweden. Metenova is projected to generate revenues of $24 million to $25 million for fiscal year 2023, led by the success of its magnetic mixing and drive train technologies that are widely used by global biopharmaceutical companies and contract development and manufacturing organizations (CDMOs). The company recently entered the single-use mixing market with the launch of its MixOne platform, leveraging the success of its existing stainless steel (repeat-use) product line.
>1000 ML accounts for the majority of the market share
The rising preference for large column sizes across different industry verticals is driving the market segment. >1000 ML prepacked columns are commonly employed for the purification of biomolecules such as monoclonal antibodies, proteins, and vaccines. They facilitate high-capacity chromatographic separations, ensuring the production of pure and high-quality biopharmaceutical products. Additionally, food and beverage (F&B) manufacturers utilize >1000 mL prepacked columns for tasks like flavor extraction, quality control, and the separation of components like sugars, amino acids, and colorants. These columns aid in achieving consistent product quality and compliance with food safety regulations. In chemical research and development (R&D), these columns are essential for synthesizing and purifying compounds. Researchers can scale up their chromatographic processes efficiently, saving time and resources while ensuring product purity.
Ion-exchange chromatography holds the majority of the market share
Ion-exchange chromatography is versatile and can be applied to a wide range of biomolecules, including proteins, nucleic acids, and other charged molecules. This adaptability makes it suitable for various research and industrial applications. Additionally, it offers excellent selectivity based on the charge of the molecules being separated. By using ion-exchange resins with different functional groups, researchers can effectively separate and purify target molecules from complex mixtures. Apart from this, it provides high-resolution separation, enabling the isolation of closely related species with different charge properties. Furthermore, it can be easily scaled up for industrial production, making it suitable for large-scale purification processes in biopharmaceuticals, food processing, and other industries.
Sample preparation represents the largest market segment
Sample preparation is a fundamental prerequisite for chromatographic analyses which is fueling the segment growth in the market. It involves the extraction, clean-up, and concentration of target molecules from complex samples, ensuring that only relevant compounds reach the chromatography columns. The quality of sample preparation directly influences the accuracy and sensitivity of subsequent chromatographic analyses, making it an essential step. Additionally, diverse industries, including pharmaceuticals, biotechnology, food and beverage, environmental monitoring, and healthcare, heavily rely on chromatography for quality control, research, and product development. Furthermore, ongoing advancements in analytical techniques, such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS), demand sample preparation methods that can cater to evolving needs.
Pharmaceutical and biotechnology companies account for the largest market share
Pharmaceutical and biotechnology companies are subject to rigorous regulatory requirements to ensure the safety and efficacy of their products which is further driving the segment growth in the market. Chromatography is a trusted and standardized method for characterizing and purifying compounds, making prepacked columns an attractive option for achieving compliance and maintaining consistency in manufacturing. Moreover, the continuous advancements in biopharmaceuticals, including monoclonal antibodies and gene therapies, have led to increased demand for specialized chromatography columns tailored to these complex molecules. Furthermore, these industries rely on precise and efficient separation and purification of biomolecules, such as proteins, antibodies, and nucleic acids, at various stages of drug development, production, and quality control. Prepacked chromatography columns offer ready-to-use solutions that significantly streamline these processes, reducing time and labor costs.
North America leads the market, accounting for the largest prepacked chromatography columns market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represents the largest regional market for prepacked chromatography columns.
North America is home to numerous pharmaceutical and biotechnology companies engaged in drug discovery, development, and production which is driving the market growth. Additionally, pharmaceutical and biotechnology sectors in North America are subject to strict regulatory standards set by the U.S. Food and Drug Administration (FDA) and Health Canada. Apart from this, several major players in the chromatography column manufacturing industry are headquartered or have a significant presence in North America. This concentration of key industry players fosters competition, innovation, and a wide range of product offerings. Furthermore, the region boasts advanced healthcare infrastructure, including cutting-edge diagnostic laboratories and healthcare facilities. Chromatography is extensively used in clinical diagnostics and research, further fueling the demand for prepacked columns. For instance, in February 2024, Shimadzu Corporation acquired the catalytic micro-reactive business for gas chromatography (GC) from Activated Research Company, LLC (ARC, Minnesota, USA).
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)