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市場調查報告書
商品編碼
1753880
2025-2033年核酸分離與純化市場報告(依產品、類型、方法、最終使用者及地區)Nucleic Acid Isolation and Purification Market Report by Product, Type, Method, End User, and Region 2025-2033 |
2024年,全球核酸分離純化市場規模達57億美元。展望未來, IMARC Group預計到2033年,該市場規模將達到105億美元,2025-2033年期間的複合年成長率(CAGR)為7.1%。分子診斷和研究需求的不斷成長、自動化和高通量技術的進步、新冠疫情的影響以及醫療保健領域以外的應用不斷擴展,是推動市場發展的主要因素。
核酸分離純化是指從各種生物樣本中分離並精製脫氧核糖核酸 (DNA) 或核糖核酸 (RNA) 分子的過程。這一關鍵步驟在分子生物學和診斷學中至關重要。在分離階段,樣本通常被裂解以釋放核酸。隨後,純化步驟包括去除污染物、蛋白質和其他細胞成分,以獲得適用於下游應用(包括聚合酶鍊式反應 (PCR)、定序或分析)的純核酸。常用的技術包括苯酚-氯仿萃取、管柱層析或磁珠法。
全球核酸分離純化市場正經歷強勁成長,這得益於醫療保健、生物技術和製藥等各領域對分子診斷和基因研究的需求不斷成長。同時,隨著個人化醫療和基因組學研究的重要性不斷提高,對高效能核酸分離純化技術的需求也日益成長,為市場擴張創造了積極的前景。此外,自動化和高通量技術的重大進步簡化了這些流程,減少了人工並提高了效率,從而促進了市場成長。此外,由於基於PCR的檢測的廣泛使用,COVID-19大流行推動了對核酸分離純化產品的需求,從而有助於市場擴張。此外,市場參與者為提高產品性能和擴展應用領域而增加對研發(R&D)的投資,也促進了市場的成長。
分子診斷和基因研究的需求不斷增加
推動核酸分離純化市場發展的主要因素之一是分子診斷和基因研究需求的不斷成長。在醫療保健領域,人們越來越重視個人化醫療,即利用基因資訊為個別患者制定個人化治療方案。這一趨勢刺激了對高效精準的核酸分離純化方法的需求。同時,研究人員和臨床醫生需要高品質的DNA和RNA樣本來進行各種分子檢測,包括PCR、定序和基因表現分析。同樣,生物技術和製藥業也高度依賴核酸分離純化來開發和測試新藥、疫苗和療法。這種跨多個領域的持續需求是市場成長的關鍵驅動力。
自動化和高通量技術的進步
推動市場成長的另一個重要因素是核酸分離純化過程中自動化和高通量技術的不斷進步。自動化系統和機器人平台的開發旨在簡化和標準化這些流程,減少對人工的依賴,並最大限度地降低污染風險。同時,高通量儀器和方法使研究人員能夠同時處理大量樣本,從而提高效率和可擴展性。這些技術創新節省了時間,並提高了核酸分離純化的可重複性和一致性,使其對尋求更高通量和更高精度的實驗室和研究機構越來越有吸引力。
COVID-19疫情的影響
持續的COVID-19疫情對核酸分離純化產業產生了重大影響。 PCR檢測是診斷COVID-19的關鍵工具,其高度依賴病毒RNA的分離和純化。 COVID-19檢測需求的激增,以及研究和監測需求的增加,導致核酸分離純化產品的使用量空前成長。市場參與者迅速適應此需求,擴大生產規模並開發用於SARS-CoV-2檢測的專用試劑盒和試劑。儘管疫情的動態可能會隨著時間的推移而發生變化,但人們對穩健的核酸分離純化過程在傳染病控制和研究中的重要性的認知不斷提高,預計將對市場成長產生持久影響。
The global nucleic acid isolation and purification market size reached USD 5.7 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 10.5 Billion by 2033, exhibiting a growth rate (CAGR) of 7.1% during 2025-2033. The increasing demand in molecular diagnostics and research, automation and high-throughput technology advancements, the impact of the COVID-19 pandemic, and expanding applications beyond healthcare are some of the major factors propelling the market.
Nucleic acid isolation and purification refers to the processes employed in separating and refining deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules from various biological samples. This essential step is crucial in molecular biology and diagnostics. The sample is typically lysed in the isolation phase to release nucleic acids. Subsequently, purification involves removing contaminants, proteins, and other cellular components to yield pure nucleic acids suitable for downstream applications, including polymerase chain reaction (PCR), sequencing, or analysis. Techniques such as phenol-chloroform extraction, column chromatography, or magnetic bead-based methods are commonly used.
The global nucleic acid isolation and purification market is experiencing robust growth driven by the increasing demand for molecular diagnostics and genetic research across various fields, including healthcare, biotechnology, and pharmaceuticals. In line with this, as the importance of personalized medicine and genomics research continues to rise, there is a surging need for efficient nucleic acid isolation and purification techniques, creating a positive outlook for market expansion. Moreover, significant advancements in automation and high-throughput technologies have streamlined these processes, reducing manual labor and improving efficiency, thereby fostering market growth. In addition to this, the COVID-19 pandemic has impelled the demand for nucleic acid isolation and purification products due to the extensive use of PCR-based testing, thereby aiding in market expansion. Furthermore, rising investments in research and development (R&D) by market players to enhance product performance and expand application areas are contributing to the market's growth.
Increasing demand for molecular diagnostics and genetic research
One of the primary factors driving the nucleic acid isolation and purification market is the growing demand for molecular diagnostics and genetic research. In the healthcare sector, there is a rising emphasis on personalized medicine, where genetic information is used to tailor treatments to individual patients. This trend has spurred the need for efficient and accurate nucleic acid isolation and purification methods. Concurrent with this, researchers and clinicians require high-quality DNA and RNA samples to perform various molecular tests, including PCR, sequencing, and gene expression analysis. Similarly, the biotechnology and pharmaceutical industries heavily rely on nucleic acid isolation and purification to develop and test new drugs, vaccines, and therapies. This sustained demand across multiple sectors is a key driving force behind the market's growth.
Advancements in automation and high-throughput technologies
Another significant factor fueling market growth is the continuous advancement of automation and high-throughput technologies in nucleic acid isolation and purification processes. Automation systems and robotic platforms have been developed to streamline and standardize these procedures, reducing the dependence on manual labor and minimizing the risk of contamination. In line with this, High-throughput instruments and methods enable researchers to process a larger number of samples simultaneously, improving efficiency and scalability. These technological innovations save time and enhance the reproducibility and consistency of nucleic acid isolation and purification, making them increasingly attractive to laboratories and research facilities seeking higher throughput and improved precision.
Impact of the COVID-19 pandemic
The ongoing COVID-19 pandemic has exerted a significant influence on the nucleic acid isolation and purification industry. PCR-based testing, a crucial tool for diagnosing COVID-19, relies heavily on the isolation and purification of viral RNA. The surge in demand for COVID-19 testing, along with the need for research and surveillance, has led to an unprecedented uptick in the utilization of nucleic acid isolation and purification products. Market players quickly adapted to meet this demand by scaling up production and developing specialized kits and reagents for SARS-CoV-2 detection. Although the pandemic's dynamics may change over time, the heightened awareness of the importance of robust nucleic acid isolation and purification processes in infectious disease control and research is expected to have a lasting impact on the market's growth.
Kits and reagents dominate the market
The demand for nucleic acid isolation and purification products, specifically kits and reagents, is propelled by the expanding application of nucleic acid-based techniques in the fields of forensic science and environmental monitoring. These areas increasingly rely on nucleic acid isolation and purification for DNA profiling, crime scene analysis, and identifying microbial contaminants. Additionally, the growing interest in agriculture and food safety drives the need for genetic testing and traceability, spurring demand for nucleic acid products. Apart from this, the emergence of innovative and specialized kits and reagents tailored to specific applications, such as RNA sequencing or viral RNA extraction, is attracting researchers and diagnostic labs, strengthening the market growth. Furthermore, the continuous development of user-friendly, cost-effective, and high-performance products accelerate the utilization of nucleic acid isolation and purification kits and reagents across various industries, providing impetus to the market growth.
Plasmid DNA isolation and purification holds the largest share in the market
The increasing importance of plasmid DNA in biotechnology and gene therapy applications is driving the demand for plasmid DNA isolation and purification. Plasmids are vital tools for genetic engineering, gene expression, and recombinant protein production, making them indispensable in the biopharmaceutical industry. Moreover, the rise of gene and cell therapies has created a surge in the demand for high-quality plasmid DNA for vector construction and therapeutic gene delivery, aiding in market expansion. Concurrent with this, the expanding field of synthetic biology, where custom-designed plasmids are employed to create novel biological systems, fuels the need for efficient plasmid DNA isolation and purification methods. The development of advanced purification techniques, such as chromatography and membrane-based systems, further enhances the purity and yield of plasmid DNA, making them essential components in the biotechnology and medical sectors and driving market demand.
Column-based isolation and purification dominates the market
The demand for nucleic acid isolation and purification, specifically through column-based methods, is fueled by the preference for column-based techniques in research and clinical laboratories due to their efficiency, simplicity, and scalability. These methods offer researchers a reliable and convenient means of isolating and purifying nucleic acids with high purity and yield. Additionally, the versatility of column-based systems enables their use across a wide range of applications, from fundamental research to diagnostics, impelling the market growth. Moreover, advancements in column technology, such as improved matrix materials and design, have led to enhanced performance and faster processing times, making them increasingly attractive to users seeking rapid and consistent results. Furthermore, the stringent quality control requirements in genomics, molecular diagnostics, and pharmaceuticals have led to the continued adoption of column-based nucleic acid isolation and purification methods, driving sustained demand in the market.
Hospitals and diagnostic centers hold the largest share in the market
The demand for nucleic acid isolation and purification products, particularly among hospital and diagnostic end-users, is primarily driven by the growing significance of molecular diagnostics in healthcare. Hospitals and diagnostic laboratories increasingly rely on nucleic acid-based tests to accurately diagnose various diseases, including infectious diseases, cancer, and genetic disorders. This has resulted in a consistent demand for high-quality DNA and RNA samples, thus fueling the need for efficient nucleic acid isolation and purification methods. Additionally, the rapid adoption of point-of-care testing and the emergence of novel diagnostic assays have amplified the demand for streamlined nucleic acid extraction processes that can be integrated into diagnostic workflows, thereby bolstering the market growth. As precision medicine gains prominence in patient care, hospitals are also utilizing nucleic acid purification techniques for personalized treatment strategies, propelling the market forward.
North America exhibits a clear dominance, accounting for the largest nucleic acid isolation and purification market share
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America accounted for the largest market share.
North America's well-established and advanced healthcare infrastructure, along with a robust presence of pharmaceutical and biotechnology companies, has created a significant demand for nucleic acid isolation and purification products. As precision medicine and genetic research gain momentum, the need for high-quality DNA and RNA samples in North America continues to rise, driving the market's growth. In addition to this, the increasing prevalence of chronic conditions such as cancer, infectious diseases, and genetic disorders in the region has led to an elevated demand for molecular diagnostics, further boosting the requirement for efficient nucleic acid isolation and purification methods. Furthermore, North America has been at the forefront of research and development in genomics, gene therapy, and biopharmaceuticals, contributing to the adoption of advanced purification techniques and specialized kits and reagents, thus playing a pivotal role in driving market expansion in the region.
The competitive landscape of the global nucleic acid isolation and purification market is characterized by intense rivalry among key players and a dynamic ecosystem of companies providing an array of products and services. Prominent companies dominate the market with their extensive product portfolios, global reach, and continuous investments in research and development. Additionally, a multitude of smaller and niche players cater to specialized segments and applications within the market, providing innovative solutions and fostering competition. Collaborations and partnerships between market players and research institutions are commonplace, further intensifying competition and driving innovation. As the market continues to expand, new entrants are attracted to its potential, contributing to a dynamic competitive landscape.