Product Code: GVR-4-68040-547-9
Residual Solvents Market Growth & Trends:
The global residual solvents market size is anticipated to reach USD 2.00 billion by 2030, registering a CAGR of 5.0% from 2025 to 2030, according to a new report by Grand View Research, Inc. The expansion of the pharmaceutical and biotechnology industries, particularly in drug formulation, API manufacturing, and biologics, increases the demand for solvent testing. Additionally, growing consumer awareness and quality standards in cosmetics and food safety further propel market growth. Technological advancements in gas chromatography (GC) and mass spectrometry (GC-MS) enhance detection accuracy, driving adoption.
The class 2 segment dominated the residual solvents industry with a revenue share of 38.9% in 2024, during the forecast period. Class 2 residual solvents are solvents with moderate toxicity that must be limited in pharmaceutical, food, and cosmetic products to ensure safety. Examples include methanol, toluene, and dichloromethane, which are commonly used in manufacturing but require strict regulation under ICH guidelines to minimize health risks.
The pharmaceuticals segment dominated the market with a revenue share of 58.3% in 2024, during the forecast period. The pharmaceutical segment dominated due to the extensive use of solvents in drug synthesis, formulation, and purification. Regulatory bodies like the FDA, ICH, and EMA enforce strict solvent limits to ensure drug safety and compliance. Advanced analytical techniques such as gas chromatography (GC) and mass spectrometry (GC-MS) are widely used for solvent detection in pharmaceutical manufacturing.
North America dominated the market with a market share of 54.34% in 2024, during the forecast period. The region's well-established pharmaceutical and biotechnology industries, along with advancements in analytical technologies like gas chromatography (GC) and mass spectrometry (GC-MS), drive market growth. Additionally, increasing consumer awareness, demand for high-purity products, and the presence of leading analytical instrument manufacturers further boost the market.
Residual Solvents Market Report Highlights:
- The class 2 segment is held the largest revenue share of 38.9% in 2024.The Class 2 segment held the largest share due to the moderate toxicity of these solvents, requiring strict regulation in pharmaceuticals, food, and cosmetics. Solvents like toluene, methanol, and dichloromethane are widely used but must comply with ICH-permissible daily exposure (PDE) limits to ensure product safety.
- North America was the dominant region for the residual solvents industry with a revenue share of 54.34% in 2024. North America led the market due to strict regulatory standards from the FDA, USP, and ICH, ensuring safety in pharmaceuticals, food, and cosmetics. The region's strong pharmaceutical sector and advancements in analytical technologies further drive market growth.
- In March 2023, The United States Pharmacopeia (USP) has revised Chapter <467> "Residual Solvents" to align with the updated ICH guideline Q3C (R8) on impurities. This revision introduces two Class 2 solvents, cyclopentyl methyl ether and tertiary butyl alcohol, and one Class 3 solvent, 2-methyltetrahydrofuran, necessitating updates to related sections and appendices.
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.2. Market Definition
- 1.3. Information Procurement
- 1.3.1. Information Analysis
- 1.3.2. Market Formulation & Data Visualization
- 1.3.3. Data Validation & Publishing
- 1.4. Research Scope and Assumptions
- 1.4.1. List of Data Sources
Chapter 2. Executive Summary
- 2.1. Market Snapshot
- 2.2. Segmental Outlook
- 2.3. Competitive Outlook
Chapter 3. Market Variables, Trends, and Scope
- 3.1. Global Residual Solvents Market Outlook
- 3.2. Value Chain Analysis
- 3.2.1. Raw Material Outlook
- 3.2.2. Food & Beverage/Product Outlook
- 3.2.3. Sales Channel Analysis
- 3.3. Price Trend Analysis
- 3.3.1. Factors Influencing Prices
- 3.4. Regulatory Framework
- 3.4.1. Standards & Compliances
- 3.5. Market Dynamics
- 3.5.1. Market Driver Analysis
- 3.5.2. Market Restraint Analysis
- 3.5.3. Market Challenges Analysis
- 3.5.4. Market Opportunity Analysis
- 3.6. Porter's Five Forces Analysis
- 3.6.1. Bargaining Power of Suppliers
- 3.6.2. Bargaining Power of Buyers
- 3.6.3. Threat of Substitution
- 3.6.4. Threat of New Entrants
- 3.6.5. Competitive Rivalry
- 3.7. PESTLE Analysis
- 3.7.1. Political
- 3.7.2. Economic
- 3.7.3. Social Landscape
- 3.7.4. Product
- 3.7.5. Environmental
- 3.7.6. Legal
Chapter 4. Residual Solvents Market: Type Estimates & Trend Analysis
- 4.1. Residual Solvents Market: Type Movement Analysis, 2023 & 2030
- 4.2. Class 1
- 4.2.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 4.3. Class 2
- 4.3.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 4.4. Class 3
- 4.4.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
Chapter 5. Residual Solvents Market: Application Estimates & Trend Analysis
- 5.1. Residual Solvents Market: Application Movement Analysis, 2023 & 2030
- 5.2. Pharmaceuticals
- 5.2.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 5.3. Food & Beverage
- 5.3.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 5.4. Cosmetics
- 5.4.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 5.5. Industrial
- 5.5.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
Chapter 6. Residual Solvents Market: Regional Estimates & Trend Analysis
- 6.1. Regional Analysis, 2023 & 2030
- 6.2. North America
- 6.2.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.2.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.2.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.2.4. U.S.
- 6.2.4.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.2.4.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.2.4.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.2.5. Canada
- 6.2.5.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.2.5.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.2.5.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.2.6. Mexico
- 6.2.6.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.2.6.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.2.6.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.3. Europe
- 6.3.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.3.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.3.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.3.4. Germany
- 6.3.4.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.3.4.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.3.4.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.3.5. UK
- 6.3.5.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.3.5.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.3.5.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.3.6. France
- 6.3.6.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.3.6.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.3.6.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.3.7. Italy
- 6.3.7.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.3.7.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.3.7.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.3.8. Spain
- 6.3.8.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.3.8.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.3.8.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.4. Asia Pacific
- 6.4.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.4.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.4.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.4.4. China
- 6.4.4.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.4.4.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.4.4.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.4.5. India
- 6.4.5.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.4.5.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.4.5.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.4.6. Japan
- 6.4.6.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.4.6.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.4.6.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.4.7. South Korea
- 6.4.7.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.4.7.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.4.7.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.5. Latin America
- 6.5.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.5.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.5.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.5.4. Brazil
- 6.5.4.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.5.4.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.5.4.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.5.5. Argentina
- 6.5.5.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.5.5.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.5.5.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.6. Middle East & Africa
- 6.6.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.6.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.6.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.6.4. Saudi Arabia
- 6.6.4.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.6.4.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.6.4.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
- 6.6.5. South Africa
- 6.6.5.1. Market estimates and forecasts, 2018 - 2030 (USD Billion)
- 6.6.5.2. Market estimates and forecasts, by type, 2018 - 2030 (USD Billion)
- 6.6.5.3. Market estimates and forecasts, by application, 2018 - 2030 (USD Billion)
Chapter 7. Competitive Landscape
- 7.1. Recent Developments by Key Market Participants
- 7.2. Company Categorization
- 7.3. Company Heat Map Analysis
- 7.4. Company Market Positioning Analysis, 2024
- 7.5. Strategy Mapping
- 7.6. Company Profiles/Listing
- 7.6.1. Agilent Technology
- 7.6.1.1. Company Overview
- 7.6.1.2. Financial Performance
- 7.6.1.3. Product Benchmarking
- 7.6.2. Thermo Fisher Scientific
- 7.6.2.1. Company Overview
- 7.6.2.2. Financial Performance
- 7.6.2.3. Product Benchmarking
- 7.6.3. Techcomp
- 7.6.3.1. Company Overview
- 7.6.3.2. Financial Performance
- 7.6.3.3. Product Benchmarking
- 7.6.4. LECO
- 7.6.4.1. Company Overview
- 7.6.4.2. Financial Performance
- 7.6.4.3. Product Benchmarking
- 7.6.5. Fuli Instruments
- 7.6.5.1. Company Overview
- 7.6.5.2. Financial Performance
- 7.6.5.3. Product Benchmarking
- 7.6.6. Shimadzu
- 7.6.6.1. Company Overview
- 7.6.6.2. Financial Performance
- 7.6.6.3. Product Benchmarking
- 7.6.7. PerkinElmer
- 7.6.7.1. Company Overview
- 7.6.7.2. Financial Performance
- 7.6.7.3. Product Benchmarking
- 7.6.8. Beifenruili
- 7.6.8.1. Company Overview
- 7.6.8.2. Financial Performance
- 7.6.8.3. Product Benchmarking
- 7.6.9. Bruker
- 7.6.9.1. Company Overview
- 7.6.9.2. Financial Performance
- 7.6.9.3. Product Benchmarking