肌肉骨骼合作與授權協議（2016-2025）

"肌肉骨骼合作與許可交易" 報告以前所未有的方式，全面深入地展現了全球領先的生物製藥公司達成的肌肉骨骼交易。

本報告詳細介紹了2016年至2025年間476項肌肉骨骼交易。

本報告提供了交易雙方已公佈的付款條款。這些數據有助於深入了解付款條款和其他交易條款。

了解潛在合作夥伴協商條款的彈性，有助於深入了解條款談判過程中可能出現的情況。許多中小企業會尋求詳細的付款條款，但魔鬼藏在細節裡，尤其是在付款方式和權利轉讓方面。

本報告全面列出了自 2016 年以來在 "當前協議" 交易和合作資料庫中記錄的所有合作與許可協議，並附有財務條款（如有），以及公司及其合作夥伴向美國證券交易委員會提交的實際許可協議文件的在線鏈接。

本報告第一章概述了肌肉骨骼領域的交易和商業活動。第一章為報告的引言，第二章分析了肌肉骨骼領域的交易趨勢。

第三章介紹了肌肉骨骼領域已達成交易的財務條款及其所處的研發階段。交易按總價值、首付款、里程碑付款和特許權使用費率進行分類。

第四章回顧了在肌肉骨骼領域交易中最活躍的 25 家生物製藥公司。 對於已公開揭露協議的交易，可透過 "目前協議交易與聯盟" 資料庫線上存取這些協議的連結。

第五章對自 2016 年以來簽署和宣布的、且有協議文件可供查閱的肌肉骨骼系統交易進行了全面深入的回顧。每個交易標題均透過網路連結指向實際的線上協議文件，方便讀者隨時查閱。

第六章按目標公司列出了肌肉骨骼系統交易的完整目錄。

本書還包含大量圖表，展示了自 2016 年以來肌肉骨骼系統交易的趨勢和活動。

此外，此綜合交易目錄按公司名稱（A-Z）和技術類型進行組織。每個交易標題均透過網路連結指向線上交易記錄，並在可用的情況下包含協議文件，方便讀者隨時查閱。

主要優勢

肌肉骨骼合作研究與授權協議為讀者提供以下主要優勢：

• 了解自 2016 年以來的交易趨勢
• 瀏覽肌肉骨骼合作與許可交易
• 基準分析 - 確定交易市場價值
• 財務條款 - 預付款、里程碑付款、特許權使用費
• 按公司 A-Z、治療領域和技術類型分類的交易目錄
• 主要交易金額
• 最活躍的交易撮合者
• 確定每筆交易的資產和交易條款
• 存取合約文件 - 深入了解交易結構
• 盡職調查 - 評估擬議交易條款是否適合您的合作夥伴
• 節省數百小時的研究時間

範圍

• "肌肉骨骼合作與許可協議" 旨在深入解讀全球領先的生物製藥公司簽署的肌肉骨骼合作與許可協議。

肌肉骨骼合作與許可交易包括：

• 生物製藥產業肌肉骨骼交易趨勢
• 合作與授權協議架構概述
• 涵蓋製藥和生物技術的肌肉骨骼交易記錄目錄
• 主要肌肉骨骼交易
• 最活躍的肌肉骨骼許可交易撮合者

肌肉骨骼合作與授權交易清單列出了所有可用的交易。

• 公司 A-Z
• 主要交易金額
• 治療領域
• 技術類型
• 每個交易標題都透過網路連結連結到實際的線上交易記錄，方便您輕鬆存取每個協議文件（如有）。
• 肌肉骨骼合作與許可交易資料庫提供全面的交易記錄存取權限，包括協議文件。

合約分析可對以下方面進行盡職調查：

• 具體授予或選擇哪些權利？
• 合約夥伴實際獲得哪些權利？
• 授予哪些獨家經營權？
• 合約的付款結構是什麼？
• 如何進行銷售和付款審計？
• 合約期限是多久？
• 如何定義合約的關鍵條款？
• 如何處理並擁有知識產權？
• 誰負責商業化？
• 誰負責開發、供應和生產？
• 如何管理保密性和資訊揭露？
• 如何解決爭議？
• 在什麼情況下可以終止合約？
• 如果所有權發生變更，會發生什麼事？
• 已達成哪些轉許可或分包條款？
• 公司堅持哪些標準條款？
• 哪些格式條款似乎會因合作夥伴和交易類型而異？
• 公司主張適用哪個契約法管轄區？

目錄

摘要整理

第一章：引言

第二章：肌肉骨骼交易趨勢

• 引言
• 歷年肌肉骨骼合作狀況
• 按交易類型劃分的肌肉骨骼合作
• 按行業劃分的肌肉骨骼合作
• 依研發階段劃分的肌肉骨骼合作
• 按技術類型劃分的肌肉骨骼合作
• 依治療適應症劃分的肌肉骨骼合作

第三章 - 肌肉骨骼合作的財務條款

• 引言
• 揭露財務條款肌肉骨骼合作
• 肌肉骨骼合作的關鍵價值
• 肌肉骨骼交易的預付款
• 肌肉骨骼交易的里程碑付款
• 肌肉骨骼特許權使用費率

第四章 - 關鍵肌肉骨骼交易及交易撮合者

• 引言
• 肌肉骨骼合作中最活躍的參與者
• 最活躍的肌肉骨骼交易撮合者名單
• 頂級肌肉骨骼交易（按價格排序）

第五章 - 肌肉骨骼合約文件目錄

• 引言
• 肌肉骨骼合作協議及可用合約

第六章依治療標靶劃分的肌肉骨骼系統交易

• 簡介
• 以肌肉骨骼系統治療標靶劃分的交易
• 交易目錄
• 交易目錄 - 肌肉骨骼系統交易（按公司、亞利桑那州、2016-2025 年）
• 交易目錄 - 肌肉骨骼系統交易（依技術類型、2016-2025 年）
• 交易類型定義
• 關於研究公司
• 當前合作關係
• 當前協議
• 近期當前合作關係報告標題

Musculoskeletal Collaboration and Licensing Deals provides a comprehensive understanding and unprecedented access to the musculoskeletal deals entered into by the worlds leading biopharma companies.

Fully revised and updated, the report provides details of 476 musculoskeletal deals from 2016 to 2025.

The report provides access to deal payment terms as announced between the parties. This data provides useful insight into the payment and other deal terms.

Understanding the flexibility of a prospective partner's negotiated deals terms provides critical insight into the negotiation process in terms of what you can expect to achieve during the negotiation of terms. Whilst many smaller companies will be seeking details of the payments clauses, the devil is in the detail in terms of how payments are triggered and rights transferred - contract documents provide this insight where press releases and databases do not.

This report contains a comprehensive listing of collaboration and licensing deals announced since 2016 as recorded in the Current Agreements deals and alliances database, including financial terms where available, plus links to online copies of actual licensing contract documents as submitted to the Securities Exchange Commission by companies and their partners.

The initial chapters of this report provide an orientation of musculoskeletal dealmaking and business activities. Chapter 1 provides an introduction to the report, whilst chapter 2 provides an analysis of the trends in musculoskeletal dealmaking.

Chapter 3 covers the financial deal terms for deals signed in the musculoskeletal field with stage of development announced. Deals are listed and sectioned by headline value, upfront payment, milestone payment and royalty rates.

Chapter 4 provides a review of the top 25 most active biopharma companies in musculoskeletal dealmaking. Where the deal has an agreement contract published at the SEC a link provides online access to the contract via the Current Agreements deals and alliances database.

Chapter 5 provides a comprehensive and detailed review of musculoskeletal deals signed and announced since 2016 where a contract document is available. Each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

Chapter 6 provides a comprehensive directory of musculoskeletal deals listed by theraeutic target.

The report also includes numerous table and figures that illustrate the trends and activities in musculoskeletal deal making since 2016.

In addition, a comprehensive deal directory is provided organized by company A-Z and technology type. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

Key benefits

Musculoskeletal Collaboration and Licensing Deals provides the reader with the following key benefits:

• Understand deal trends since 2016
• Browse musculoskeletal collaboration and licensing deals
• Benchmark analysis - identify market value of transactions
• Financials terms - upfront, milestone, royalties
• Directory of deals by company A-Z, therapy focus and technology type
• Leading deals by value
• Most active dealmakers
• Identify assets and deal terms for each transaction
• Access contract documents - insights into deal structures
• Due diligence - assess suitability of your proposed deal terms for partner companies
• Save hundreds of hours of research time

Report scope

• Musculoskeletal Collaboration and Licensing Deals is intended to provide the reader with an in-depth understanding of musculoskeletal trends and structure of deals entered into by leading biopharma companies worldwide.

Musculoskeletal Collaboration and Licensing Deals includes:

• Trends in musculoskeletal dealmaking in the biopharma industry
• Overview of collaboration and licensing deal structure
• Directory of musculoskeletal deal records covering pharmaceutical and biotechnology
• The leading musculoskeletal deals by value
• Most active musculoskeletal licensing dealmakers

In Musculoskeletal Collaboration and Licensing Deals, the available deals are listed by:

• Company A-Z
• Headline value
• Therapeutic area
• Technology type
• Each deal title links via Weblink to an online version of the actual deal record, providing easy access to each contract document where available.
• Musculoskeletal Collaboration and Licensing Deals provides comprehensive access to available records for deals, including contract documents where available.

Analyzing contract agreements allows due diligence of:

• What are the precise rights granted or optioned?
• What is actually granted by the agreement to the partner company?
• What exclusivity is granted?
• What is the payment structure for the deal?
• How are sales and payments audited?
• What is the deal term?
• How are the key terms of the agreement defined?
• How are IPRs handled and owned?
• Who is responsible for commercialization?
• Who is responsible for development, supply, and manufacture?
• How is confidentiality and publication managed?
• How are disputes to be resolved?
• Under what conditions can the deal be terminated?
• What happens when there is a change of ownership?
• What sublicensing and subcontracting provisions have been agreed?
• Which boilerplate clauses does the company insist upon?
• Which boilerplate clauses appear to differ from partner to partner or deal type to deal type?
• Which jurisdiction does the company insist upon for agreement law?

Table of Contents

Executive Summary

Chapter 1 - Introduction

Chapter 2 - Trends in musculoskeletal dealmaking

• 2.1. Introduction
• 2.2. Musculoskeletal partnering over the years
• 2.3. Musculoskeletal partnering by deal type
• 2.4. Musculoskeletal partnering by industry sector
• 2.5. Musculoskeletal partnering by stage of development
• 2.6. Musculoskeletal partnering by technology type
• 2.7. Musculoskeletal partnering by therapeutic indication

Chapter 3 - Financial deal terms for musculoskeletal partnering

• 3.1. Introduction
• 3.2. Disclosed financials terms for musculoskeletal partnering
• 3.3. Musculoskeletal partnering headline values
• 3.4. Musculoskeletal deal upfront payments
• 3.5. Musculoskeletal deal milestone payments
• 3.6. Musculoskeletal royalty rates

Chapter 4 - Leading musculoskeletal deals and dealmakers

• 4.1. Introduction
• 4.2. Most active in musculoskeletal partnering
• 4.3. List of most active dealmakers in musculoskeletal
• 4.4. Top musculoskeletal deals by value

Chapter 5 - Musculoskeletal contract document directory

• 5.1. Introduction
• 5.2. Musculoskeletal partnering deals where contract document available

Chapter 6 - Musculoskeletal dealmaking by therapeutic target

• 6.1. Introduction
• 6.2. Deals by musculoskeletal therapeutic target
• Deal directory
• Deal directory - Musculoskeletal deals by company A-Z 2016 to 2025
• Deal directory - Musculoskeletal deals by technology type 2016 to 2025
• Deal type definitions
• About Biopharma Research Ltd
• Current Partnering
• Current Agreements
• Recent report titles from Current Partnering

Table of figures

• Figure 1: Musculoskeletal partnering since 2016
• Figure 2: Musculoskeletal partnering by deal type since 2016
• Figure 3: Musculoskeletal partnering by industry sector since 2016
• Figure 4: Musculoskeletal partnering by stage of development since 2016
• Figure 5: Musculoskeletal partnering by technology type since 2016
• Figure 6: Musculoskeletal partnering by indication since 2016
• Figure 7: Musculoskeletal deals with a headline value
• Figure 8: Musculoskeletal deals with upfront payment values
• Figure 9: Musculoskeletal deals with milestone payment
• Figure 10: Musculoskeletal deals with royalty rates
• Figure 11: Active musculoskeletal dealmaking activity since 2016
• Figure 12: Top musculoskeletal deals by value since 2016