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市場調查報告書
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1965409

結構生物學和分子建模技術市場－全球產業規模、佔有率、趨勢、機會、預測：按工具、應用、地區和競爭對手分類，2021-2031年

Structural Biology & Molecular Modeling Techniques Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Tools, By Application, By Region & Competition, 2021-2031F
出版日期: | 出版商: TechSci Research | 英文 185 Pages | 商品交期: 2-3個工作天內

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簡介目錄

全球結構生物學和分子建模技術市場預計將從 2025 年的 27.6 億美元大幅成長至 2031 年的 46.8 億美元，複合年成長率為 9.21%。

該領域涵蓋旨在闡明生物大分子3D結構的實驗和計算方法。該市場的成長主要受治療慢性疾病的新型療法的巨大需求所驅動。精準的標靶分子鑑定對於降低臨床試驗的脫落率至關重要。此外，製藥業為加速藥物研發週期而進行的合理化藥物設計策略轉型，也是推動這些分析技術在藥物發現過程中廣泛應用的重要因素。

市場概覽
預測期 2027-2031
市場規模：2025年 27.6億美元
市場規模：2031年 46.8億美元
複合年成長率：2026-2031年 9.21%
成長最快的細分市場 SaaS 與獨立建模
最大的市場 北美洲

然而，高解析度設備（例如冷凍電鏡）所需的大量資本投入限制了小規模研究機構進入市場，並阻礙了整個產業的擴張。全球蛋白質資料庫的數據顯示，2024年將有15,471個新的生物大分子結構發表，展現了該領域驚人的生產力。然而，產生和管理如此龐大的資料集所帶來的高昂成本和技術複雜性，對那些資源有限的機構而言，是進入這一領域的巨大障礙。

市場促進因素

人工智慧和機器學習演算法的快速普及正在從根本上改變全球結構生物學和分子建模技術市場，顯著提升了聚合物結構預測的速度和準確性。這些計算技術的進步使研究人員能夠繞過傳統繁瑣的實驗方法，快速識別複雜蛋白質標靶上的潛在藥物結合位點。這些人工智慧驅動技術的商業性價值在領先製藥公司之間的合作中顯而易見。例如，Isomorphic Labs於2024年1月與禮來公司達成合作，共同開發小分子治療藥物，其中Isomorphic Labs支付了4500萬美元的預付款，潛在合約價值高達17億美元，這充分體現了人工智慧在簡化藥物發現早期階段的關鍵作用。

同時，全球慢性病和感染疾病率上升迫使製藥業拓展其結構生物學業務，以加速治療方案的研發。疾病日益複雜化，需要精準的分子建模來最大限度地減少脫靶效應並最佳化藥物療效。例如，世界衛生組織（WHO）報告稱，2022年全球新增癌症病例約2000萬例，死亡病例約970萬例，凸顯了研發新型癌症治療方法的緊迫性。對高效藥物研發解決方案的激增需求直接推動了技術提供商的財務成長，Schrödinger公司2024會計年度報告便印證了這一點，該報告顯示其全年收入達2.167億美元（同比成長19.7%）。

市場挑戰

全球結構生物學和分子建模技術市場成長的一大障礙是高解析度設備所需的巨額資本投入。先進的分析工具，尤其是冷凍電鏡，除了高昂的維護成本外，還需要數百萬美元的初始投資。這一經濟壁壘有效地將很大一部分潛在客戶拒之門外，特別是資金有限的中小型生物技術公司和學術研究機構。因此，市場仍集中在資金雄厚的製藥巨頭手中，限制了這些關鍵藥物研發技術的應用。

生命科學領域資金籌措環境的惡化加劇了這些經濟限制因素，進一步限制了小規模企業購買資本密集硬體的能力。麻州生技委員會的數據顯示，預計到2024年，生物製藥公司的創業投資資金籌措輪數將降至222輪，年減。投資活動的減少表明，新興企業優先考慮業務永續營運而非基礎設施擴張，它們無法獲得購買昂貴系統所需的資金，這直接限制了市場規模，減緩了結構生物學技術的整體商業性發展。

市場趨勢

業界正經歷著向雲端原生和SaaS分子建模平台的變革性轉變，這使得先進運算工具的獲取更加普及，並減少了對昂貴的本地基礎設施的依賴。生命科學機構正在加速向可擴展的雲端環境遷移，以有效處理生物模擬和即時協作所需的大型資料集。這種轉變使研究團隊能夠在最佳化營運成本的同時，加快先導化合物的最佳化，這一趨勢也反映在領先供應商的財務表現上。例如，Certara報告稱，受生物模擬技術需求的推動，其2024年第四季的軟體收入達到4,230萬美元，年增26%。

同時，混合結構測定調查方法的普及正在拓展市場能力，突破單一技術的限制。透過整合來自核磁共振（NMR）波譜、冷凍電鏡和X光晶體衍射等多種分析技術的數據，研究人員現在可以建立更全面的生物大分子動態模型。這種整合策略對於研究靜態成像技術無法完全闡明的複雜蛋白質動力學至關重要，並推動了對配套測量儀器的持續投資。例如，布魯克公司於2025年10月宣布，已獲得價值約1,000萬美元的先進NMR系統訂單，以支持頂尖機構進行高影響力結構生物學研究。

目錄

第1章概述

第2章：調查方法

第3章執行摘要

第4章：客戶心聲

第5章：結構生物學與分子建模技術的全球市場展望

  • 市場規模及預測
    • 按金額
  • 市佔率及預測
    • 依工具分類（SaaS/獨立建模工具、視覺化/分析工具、其他工具）
    • 按應用領域（藥物開發、藥物發現、其他）
    • 按地區
    • 按公司（2025 年）
  • 市場地圖

第6章：北美結構生物學與分子建模技術市場展望

  • 市場規模及預測
  • 市佔率及預測
  • 北美洲：國別分析
    • 美國
    • 加拿大
    • 墨西哥

第7章：歐洲結構生物學與分子建模技術市場展望

  • 市場規模及預測
  • 市佔率及預測
  • 歐洲：國別分析
    • 德國
    • 法國
    • 英國
    • 義大利
    • 西班牙

第8章：亞太地區結構生物學與分子建模技術市場展望

  • 市場規模及預測
  • 市佔率及預測
  • 亞太地區：國別分析
    • 中國
    • 印度
    • 日本
    • 韓國
    • 澳洲

第9章：中東和非洲結構生物學和分子建模技術市場展望

  • 市場規模及預測
  • 市佔率及預測
  • 中東與非洲：國別分析
    • 沙烏地阿拉伯
    • 阿拉伯聯合大公國
    • 南非

第10章：南美洲結構生物學與分子建模技術市場展望

  • 市場規模及預測
  • 市佔率及預測
  • 南美洲：國別分析
    • 巴西
    • 哥倫比亞
    • 阿根廷

第11章 市場動態

  • 促進因素
  • 任務

第12章 市場趨勢與發展

  • 併購
  • 產品發布
  • 近期趨勢

第13章：全球結構生物學與分子建模技術市場：SWOT分析

第14章：波特五力分析

  • 產業競爭
  • 新進入者的潛力
  • 供應商的議價能力
  • 顧客權力
  • 替代品的威脅

第15章 競爭格局

  • Charles River System Inc.
  • Acellera Ltd
  • Agile Molecule
  • Agilent Technologies Inc.
  • Biomax Informatics AG
  • Bruker Corporation
  • Chemical Computing Group
  • Dassault Systemes
  • Illumina Inc.
  • ThermoFisher Scientific Inc

第16章 策略建議

第17章：關於研究公司及免責聲明

簡介目錄
Product Code: 23478

The Global Structural Biology & Molecular Modeling Techniques Market is projected to expand significantly, growing from USD 2.76 Billion in 2025 to USD 4.68 Billion by 2031 at a CAGR of 9.21%. This sector encompasses both experimental and computational methodologies designed to decipher the three-dimensional architecture of biological macromolecules. The market is primarily propelled by the critical demand for novel therapeutics to address chronic diseases, which requires precise target identification to mitigate clinical attrition rates. Furthermore, the pharmaceutical industry's strategic pivot toward rational drug design to accelerate development cycles serves as a key catalyst for the widespread adoption of these analytical technologies throughout drug discovery pipelines.

Market Overview
Forecast Period2027-2031
Market Size 2025USD 2.76 Billion
Market Size 2031USD 4.68 Billion
CAGR 2026-20319.21%
Fastest Growing SegmentSaaS and Standalone Modeling
Largest MarketNorth America

However, the substantial capital expenditure required for high-resolution instrumentation, such as cryo-electron microscopes, restricts market access for smaller research entities and hinders broader industry expansion. Data from the Worldwide Protein Data Bank indicates that 15,471 new biological macromolecular structures were released in 2024, demonstrating the sector's immense productivity. Despite this output, the exorbitant costs and technical intricacies associated with generating and managing such vast datasets present significant barriers for resource-constrained organizations attempting to establish a foothold in this specialized field.

Market Driver

The rapid assimilation of AI and machine learning algorithms is fundamentally transforming the Global Structural Biology & Molecular Modeling Techniques Market by drastically enhancing the speed and accuracy of macromolecular structure prediction. These computational advancements allow researchers to bypass traditional, time-intensive experimental methods, facilitating the quick identification of druggable pockets on complex protein targets. The commercial significance of these AI-driven capabilities is highlighted by major pharmaceutical alliances, such as Isomorphic Labs' January 2024 partnership with Lilly to discover small molecule therapeutics, which involved a $45 million upfront payment and a potential deal value reaching $1.7 billion, confirming AI's indispensable role in streamlining early-stage discovery.

Concurrently, the rising global incidence of chronic and infectious diseases is compelling the pharmaceutical sector to scale its structural biology operations to hasten therapeutic development. The growing prevalence of complex conditions necessitates precise molecular modeling to minimize off-target effects and optimize drug efficacy. For instance, the World Health Organization reported approximately 20 million new cancer cases and 9.7 million deaths globally in 2022, underscoring the urgent need for novel oncology treatments. This surge in demand for effective drug design solutions is directly fueling financial growth for technology providers, as evidenced by Schrodinger's February 2024 report showing a 19.7% increase in full-year revenue to $216.7 million.

Market Challenge

A major impediment to the growth of the Global Structural Biology & Molecular Modeling Techniques Market is the immense capital investment required for high-resolution instrumentation. Advanced analytical tools, particularly cryo-electron microscopes, necessitate multimillion-dollar initial outlays alongside high ongoing maintenance costs. This financial barrier effectively excludes a large segment of the potential customer base, specifically small-to-medium biotechnology firms and academic laboratories with limited endowments. As a result, the market remains heavily concentrated among well-funded pharmaceutical giants, restricting the widespread deployment of these critical drug discovery technologies.

This economic constraint is exacerbated by a tightening financing environment within the life sciences sector, which further limits the ability of smaller entities to procure capital-intensive hardware. Data from the Massachusetts Biotechnology Council reveals that the total number of venture capital funding rounds for biopharmaceutical companies declined to 222 in 2024, marking a reduction from the previous year. This contraction in investment activity suggests that emerging organizations are prioritizing operational survival over infrastructure expansion, and their inability to secure necessary funding for expensive systems directly stifles market volume and slows the overall commercial development of structural biology techniques.

Market Trends

The industry is witnessing a transformative shift toward Cloud-Native and SaaS-Based Molecular Modeling Platforms, which is democratizing access to advanced computational tools and reducing reliance on expensive on-premise infrastructure. Life sciences organizations are increasingly migrating to scalable cloud environments that facilitate real-time collaboration and the efficient handling of massive datasets required for biosimulation. This transition allows research teams to accelerate lead optimization while optimizing operational expenditures, a trend reflected in the financial performance of key providers; for example, Certara reported a 26% year-over-year increase in software revenue to $42.3 million in the fourth quarter of 2024, driven by the demand for its biosimulation technologies.

In parallel, the Proliferation of Hybrid Structural Determination Methodologies is expanding the market's capabilities beyond the limitations of individual techniques. By integrating data from diverse analytical approaches such as Nuclear Magnetic Resonance (NMR) spectroscopy, cryo-electron microscopy, and X-ray crystallography, researchers can construct more comprehensive dynamic models of biological macromolecules. This integrative strategy is critical for studying complex protein dynamics that static imaging methods cannot fully resolve, promoting continued investment in complementary instrumentation. Illustrating this trend, Bruker announced in October 2025 that it secured orders valued at approximately $10 million for advanced NMR systems to support high-impact structural biology research across leading institutions.

Key Market Players

  • Charles River System Inc.
  • Acellera Ltd
  • Agile Molecule
  • Agilent Technologies Inc.
  • Biomax Informatics AG
  • Bruker Corporation
  • Chemical Computing Group
  • Dassault Systemes
  • Illumina Inc.
  • ThermoFisher Scientific Inc

Report Scope

In this report, the Global Structural Biology & Molecular Modeling Techniques Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Structural Biology & Molecular Modeling Techniques Market, By Tools

  • SaaS and Standalone Modeling
  • Visualization and Analysis
  • Other Tools

Structural Biology & Molecular Modeling Techniques Market, By Application

  • Drug Development
  • Drug Discovery
  • Others

Structural Biology & Molecular Modeling Techniques Market, By Region

  • North America
    • United States
    • Canada
    • Mexico
  • Europe
    • France
    • United Kingdom
    • Italy
    • Germany
    • Spain
  • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
  • South America
    • Brazil
    • Argentina
    • Colombia
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Structural Biology & Molecular Modeling Techniques Market.

Available Customizations:

Global Structural Biology & Molecular Modeling Techniques Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

  • Detailed analysis and profiling of additional market players (up to five).

Table of Contents

1. Product Overview

  • 1.1. Market Definition
  • 1.2. Scope of the Market
    • 1.2.1. Markets Covered
    • 1.2.2. Years Considered for Study
    • 1.2.3. Key Market Segmentations

2. Research Methodology

  • 2.1. Objective of the Study
  • 2.2. Baseline Methodology
  • 2.3. Key Industry Partners
  • 2.4. Major Association and Secondary Sources
  • 2.5. Forecasting Methodology
  • 2.6. Data Triangulation & Validation
  • 2.7. Assumptions and Limitations

3. Executive Summary

  • 3.1. Overview of the Market
  • 3.2. Overview of Key Market Segmentations
  • 3.3. Overview of Key Market Players
  • 3.4. Overview of Key Regions/Countries
  • 3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Structural Biology & Molecular Modeling Techniques Market Outlook

  • 5.1. Market Size & Forecast
    • 5.1.1. By Value
  • 5.2. Market Share & Forecast
    • 5.2.1. By Tools (SaaS and Standalone Modeling, Visualization and Analysis, Other Tools)
    • 5.2.2. By Application (Drug Development, Drug Discovery, Others)
    • 5.2.3. By Region
    • 5.2.4. By Company (2025)
  • 5.3. Market Map

6. North America Structural Biology & Molecular Modeling Techniques Market Outlook

  • 6.1. Market Size & Forecast
    • 6.1.1. By Value
  • 6.2. Market Share & Forecast
    • 6.2.1. By Tools
    • 6.2.2. By Application
    • 6.2.3. By Country
  • 6.3. North America: Country Analysis
    • 6.3.1. United States Structural Biology & Molecular Modeling Techniques Market Outlook
      • 6.3.1.1. Market Size & Forecast
        • 6.3.1.1.1. By Value
      • 6.3.1.2. Market Share & Forecast
        • 6.3.1.2.1. By Tools
        • 6.3.1.2.2. By Application
    • 6.3.2. Canada Structural Biology & Molecular Modeling Techniques Market Outlook
      • 6.3.2.1. Market Size & Forecast
        • 6.3.2.1.1. By Value
      • 6.3.2.2. Market Share & Forecast
        • 6.3.2.2.1. By Tools
        • 6.3.2.2.2. By Application
    • 6.3.3. Mexico Structural Biology & Molecular Modeling Techniques Market Outlook
      • 6.3.3.1. Market Size & Forecast
        • 6.3.3.1.1. By Value
      • 6.3.3.2. Market Share & Forecast
        • 6.3.3.2.1. By Tools
        • 6.3.3.2.2. By Application

7. Europe Structural Biology & Molecular Modeling Techniques Market Outlook

  • 7.1. Market Size & Forecast
    • 7.1.1. By Value
  • 7.2. Market Share & Forecast
    • 7.2.1. By Tools
    • 7.2.2. By Application
    • 7.2.3. By Country
  • 7.3. Europe: Country Analysis
    • 7.3.1. Germany Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.1.1. Market Size & Forecast
        • 7.3.1.1.1. By Value
      • 7.3.1.2. Market Share & Forecast
        • 7.3.1.2.1. By Tools
        • 7.3.1.2.2. By Application
    • 7.3.2. France Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.2.1. Market Size & Forecast
        • 7.3.2.1.1. By Value
      • 7.3.2.2. Market Share & Forecast
        • 7.3.2.2.1. By Tools
        • 7.3.2.2.2. By Application
    • 7.3.3. United Kingdom Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.3.1. Market Size & Forecast
        • 7.3.3.1.1. By Value
      • 7.3.3.2. Market Share & Forecast
        • 7.3.3.2.1. By Tools
        • 7.3.3.2.2. By Application
    • 7.3.4. Italy Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.4.1. Market Size & Forecast
        • 7.3.4.1.1. By Value
      • 7.3.4.2. Market Share & Forecast
        • 7.3.4.2.1. By Tools
        • 7.3.4.2.2. By Application
    • 7.3.5. Spain Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.5.1. Market Size & Forecast
        • 7.3.5.1.1. By Value
      • 7.3.5.2. Market Share & Forecast
        • 7.3.5.2.1. By Tools
        • 7.3.5.2.2. By Application

8. Asia Pacific Structural Biology & Molecular Modeling Techniques Market Outlook

  • 8.1. Market Size & Forecast
    • 8.1.1. By Value
  • 8.2. Market Share & Forecast
    • 8.2.1. By Tools
    • 8.2.2. By Application
    • 8.2.3. By Country
  • 8.3. Asia Pacific: Country Analysis
    • 8.3.1. China Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.1.1. Market Size & Forecast
        • 8.3.1.1.1. By Value
      • 8.3.1.2. Market Share & Forecast
        • 8.3.1.2.1. By Tools
        • 8.3.1.2.2. By Application
    • 8.3.2. India Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.2.1. Market Size & Forecast
        • 8.3.2.1.1. By Value
      • 8.3.2.2. Market Share & Forecast
        • 8.3.2.2.1. By Tools
        • 8.3.2.2.2. By Application
    • 8.3.3. Japan Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.3.1. Market Size & Forecast
        • 8.3.3.1.1. By Value
      • 8.3.3.2. Market Share & Forecast
        • 8.3.3.2.1. By Tools
        • 8.3.3.2.2. By Application
    • 8.3.4. South Korea Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.4.1. Market Size & Forecast
        • 8.3.4.1.1. By Value
      • 8.3.4.2. Market Share & Forecast
        • 8.3.4.2.1. By Tools
        • 8.3.4.2.2. By Application
    • 8.3.5. Australia Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.5.1. Market Size & Forecast
        • 8.3.5.1.1. By Value
      • 8.3.5.2. Market Share & Forecast
        • 8.3.5.2.1. By Tools
        • 8.3.5.2.2. By Application

9. Middle East & Africa Structural Biology & Molecular Modeling Techniques Market Outlook

  • 9.1. Market Size & Forecast
    • 9.1.1. By Value
  • 9.2. Market Share & Forecast
    • 9.2.1. By Tools
    • 9.2.2. By Application
    • 9.2.3. By Country
  • 9.3. Middle East & Africa: Country Analysis
    • 9.3.1. Saudi Arabia Structural Biology & Molecular Modeling Techniques Market Outlook
      • 9.3.1.1. Market Size & Forecast
        • 9.3.1.1.1. By Value
      • 9.3.1.2. Market Share & Forecast
        • 9.3.1.2.1. By Tools
        • 9.3.1.2.2. By Application
    • 9.3.2. UAE Structural Biology & Molecular Modeling Techniques Market Outlook
      • 9.3.2.1. Market Size & Forecast
        • 9.3.2.1.1. By Value
      • 9.3.2.2. Market Share & Forecast
        • 9.3.2.2.1. By Tools
        • 9.3.2.2.2. By Application
    • 9.3.3. South Africa Structural Biology & Molecular Modeling Techniques Market Outlook
      • 9.3.3.1. Market Size & Forecast
        • 9.3.3.1.1. By Value
      • 9.3.3.2. Market Share & Forecast
        • 9.3.3.2.1. By Tools
        • 9.3.3.2.2. By Application

10. South America Structural Biology & Molecular Modeling Techniques Market Outlook

  • 10.1. Market Size & Forecast
    • 10.1.1. By Value
  • 10.2. Market Share & Forecast
    • 10.2.1. By Tools
    • 10.2.2. By Application
    • 10.2.3. By Country
  • 10.3. South America: Country Analysis
    • 10.3.1. Brazil Structural Biology & Molecular Modeling Techniques Market Outlook
      • 10.3.1.1. Market Size & Forecast
        • 10.3.1.1.1. By Value
      • 10.3.1.2. Market Share & Forecast
        • 10.3.1.2.1. By Tools
        • 10.3.1.2.2. By Application
    • 10.3.2. Colombia Structural Biology & Molecular Modeling Techniques Market Outlook
      • 10.3.2.1. Market Size & Forecast
        • 10.3.2.1.1. By Value
      • 10.3.2.2. Market Share & Forecast
        • 10.3.2.2.1. By Tools
        • 10.3.2.2.2. By Application
    • 10.3.3. Argentina Structural Biology & Molecular Modeling Techniques Market Outlook
      • 10.3.3.1. Market Size & Forecast
        • 10.3.3.1.1. By Value
      • 10.3.3.2. Market Share & Forecast
        • 10.3.3.2.1. By Tools
        • 10.3.3.2.2. By Application

11. Market Dynamics

  • 11.1. Drivers
  • 11.2. Challenges

12. Market Trends & Developments

  • 12.1. Merger & Acquisition (If Any)
  • 12.2. Product Launches (If Any)
  • 12.3. Recent Developments

13. Global Structural Biology & Molecular Modeling Techniques Market: SWOT Analysis

14. Porter's Five Forces Analysis

  • 14.1. Competition in the Industry
  • 14.2. Potential of New Entrants
  • 14.3. Power of Suppliers
  • 14.4. Power of Customers
  • 14.5. Threat of Substitute Products

15. Competitive Landscape

  • 15.1. Charles River System Inc.
    • 15.1.1. Business Overview
    • 15.1.2. Products & Services
    • 15.1.3. Recent Developments
    • 15.1.4. Key Personnel
    • 15.1.5. SWOT Analysis
  • 15.2. Acellera Ltd
  • 15.3. Agile Molecule
  • 15.4. Agilent Technologies Inc.
  • 15.5. Biomax Informatics AG
  • 15.6. Bruker Corporation
  • 15.7. Chemical Computing Group
  • 15.8. Dassault Systemes
  • 15.9. Illumina Inc.
  • 15.10. ThermoFisher Scientific Inc

16. Strategic Recommendations

17. About Us & Disclaimer