Product Code: 20968
The Global ACE Inhibitors Market, valued at USD 6.94 Billion in 2024, is projected to experience a CAGR of 5.75% to reach USD 9.71 Billion by 2030. Angiotensin-converting enzyme (ACE) inhibitors constitute a class of pharmaceutical agents primarily utilized to relax blood vessels and reduce blood pressure, thereby managing conditions such as hypertension, heart failure, and chronic kidney disease. The market for these inhibitors is principally driven by the rising global prevalence of cardiovascular diseases and hypertension, alongside an expanding aging population.
| Market Overview |
| Forecast Period | 2026-2030 |
| Market Size 2024 | USD 6.94 Billion |
| Market Size 2030 | USD 9.71 Billion |
| CAGR 2025-2030 | 5.75% |
| Fastest Growing Segment | Oral Tablets |
| Largest Market | North America |
Key Market Drivers
The increasing global burden of cardiovascular diseases represents a fundamental driver for the ACE inhibitors market. The widespread prevalence of conditions such as hypertension and heart failure necessitates effective and accessible therapeutic options. These illnesses not only reduce quality of life but also place substantial strain on healthcare systems worldwide. According to the "Global, regional, and national burden of cardiovascular diseases and risk factors in 204 countries and territories, 1990-2023" published in JACC, in September 2025, the number of prevalent cases of cardiovascular disease reached 626 million globally in 2023, underscoring the vast and growing patient population requiring management for these conditions. This elevated disease burden directly fuels the demand for ACE inhibitors, which are cornerstone treatments for various cardiovascular ailments, driving sustained market expansion.
Key Market Challenges
The potential for adverse effects associated with angiotensin-converting enzyme (ACE) inhibitors presents a significant impediment to market expansion. These side effects, including persistent cough, hyperkalemia, and rare angioedema, frequently lead to patient non-adherence or complete discontinuation of therapy. Such reactions directly diminish the patient base that continues to utilize ACE inhibitor treatments. According to research published in *Frontiers in Cardiovascular Medicine* in 2023, approximately 23.0% of patients prescribed ACE inhibitors were non-persistent with their treatment. This substantial rate of non-persistence, often influenced by the challenges of managing adverse drug reactions, directly limits the therapeutic lifespan of ACE inhibitors for individual patients.
Key Market Trends
The growing adoption of fixed-dose combination therapies represents a pivotal trend in the Global ACE Inhibitors Market. These single-pill combinations enhance patient adherence by simplifying complex treatment regimens, which is crucial for managing chronic conditions like hypertension and heart failure. Such formulations improve therapeutic outcomes by ensuring consistent medication intake. For instance, according to a study published in *J Clin Hypertens (Greenwich)* in August 2025, patients receiving angiotensin-converting enzyme inhibitor or angiotensin receptor blocker combination therapies exhibited the highest adherence rate at 79.18% in 2022-2023, compared to other antihypertensive drug classes. This improvement in adherence directly contributes to better disease control and sustained demand for ACE inhibitor-inclusive fixed-dose combinations.
Key Market Players
- Pfizer Inc
- Novartis AG
- Johnson & Johnson
- Merck KGaA
- Sanofi S.A
- Bayer AG
- United Therapeutics Corporation
- Teva Pharmaceutical Industry
- Bristol-Myers Squibb
- Takeda Pharmaceuticals Company
Report Scope:
In this report, the Global ACE Inhibitors Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:
ACE Inhibitors Market, By Type:
- Sulfhydryl-containing Agents
- Dicarboxylate-containing Agents.
- Phosphonate-containing Agents
ACE Inhibitors Market, By Drug:
- Ramipril
- Enalapril
- Benazepril
- Fosinopril
- Captopril
- Moexipril
- Others
ACE Inhibitors Market, By Dosage Form:
- Oral Tablets
- Oral Solutions
ACE Inhibitors Market, By Application:
- Heart Failure
- Chronic Kidney Disease
- Hypertension
- Diabetes
- Heart Attack
- Others
ACE Inhibitors Market, By End user:
- Hospitals
- Online Drug Stores
- Others
ACE Inhibitors Market, By Region:
- North America
- United States
- Canada
- Mexico
- Europe
- France
- United Kingdom
- Italy
- Germany
- Spain
- Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
- South America
- Brazil
- Argentina
- Colombia
- Middle East & Africa
- South Africa
- Saudi Arabia
- UAE
Competitive Landscape
Company Profiles: Detailed analysis of the major companies presents in the Global ACE Inhibitors Market.
Available Customizations:
Global ACE Inhibitors Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:
Company Information
- Detailed analysis and profiling of additional market players (up to five).
Table of Contents
1. Product Overview
- 1.1. Market Definition
- 1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations
2. Research Methodology
- 2.1. Objective of the Study
- 2.2. Baseline Methodology
- 2.3. Key Industry Partners
- 2.4. Major Association and Secondary Sources
- 2.5. Forecasting Methodology
- 2.6. Data Triangulation & Validation
- 2.7. Assumptions and Limitations
3. Executive Summary
- 3.1. Overview of the Market
- 3.2. Overview of Key Market Segmentations
- 3.3. Overview of Key Market Players
- 3.4. Overview of Key Regions/Countries
- 3.5. Overview of Market Drivers, Challenges, Trends
4. Voice of Customer
5. Global ACE Inhibitors Market Outlook
- 5.1. Market Size & Forecast
- 5.2. Market Share & Forecast
- 5.2.1. By Type (Sulfhydryl-containing Agents, Dicarboxylate-containing Agents., Phosphonate-containing Agents)
- 5.2.2. By Drug (Ramipril, Enalapril, Benazepril, Fosinopril, Captopril, Moexipril, Others)
- 5.2.3. By Dosage Form (Oral Tablets, Oral Solutions)
- 5.2.4. By Application (Heart Failure, Chronic Kidney Disease, Hypertension, Diabetes, Heart Attack, Others)
- 5.2.5. By End user (Hospitals, Online Drug Stores, Others)
- 5.2.6. By Region
- 5.2.7. By Company (2024)
- 5.3. Market Map
6. North America ACE Inhibitors Market Outlook
- 6.1. Market Size & Forecast
- 6.2. Market Share & Forecast
- 6.2.1. By Type
- 6.2.2. By Drug
- 6.2.3. By Dosage Form
- 6.2.4. By Application
- 6.2.5. By End user
- 6.2.6. By Country
- 6.3. North America: Country Analysis
- 6.3.1. United States ACE Inhibitors Market Outlook
- 6.3.1.1. Market Size & Forecast
- 6.3.1.2. Market Share & Forecast
- 6.3.1.2.1. By Type
- 6.3.1.2.2. By Drug
- 6.3.1.2.3. By Dosage Form
- 6.3.1.2.4. By Application
- 6.3.1.2.5. By End user
- 6.3.2. Canada ACE Inhibitors Market Outlook
- 6.3.2.1. Market Size & Forecast
- 6.3.2.2. Market Share & Forecast
- 6.3.2.2.1. By Type
- 6.3.2.2.2. By Drug
- 6.3.2.2.3. By Dosage Form
- 6.3.2.2.4. By Application
- 6.3.2.2.5. By End user
- 6.3.3. Mexico ACE Inhibitors Market Outlook
- 6.3.3.1. Market Size & Forecast
- 6.3.3.2. Market Share & Forecast
- 6.3.3.2.1. By Type
- 6.3.3.2.2. By Drug
- 6.3.3.2.3. By Dosage Form
- 6.3.3.2.4. By Application
- 6.3.3.2.5. By End user
7. Europe ACE Inhibitors Market Outlook
- 7.1. Market Size & Forecast
- 7.2. Market Share & Forecast
- 7.2.1. By Type
- 7.2.2. By Drug
- 7.2.3. By Dosage Form
- 7.2.4. By Application
- 7.2.5. By End user
- 7.2.6. By Country
- 7.3. Europe: Country Analysis
- 7.3.1. Germany ACE Inhibitors Market Outlook
- 7.3.1.1. Market Size & Forecast
- 7.3.1.2. Market Share & Forecast
- 7.3.1.2.1. By Type
- 7.3.1.2.2. By Drug
- 7.3.1.2.3. By Dosage Form
- 7.3.1.2.4. By Application
- 7.3.1.2.5. By End user
- 7.3.2. France ACE Inhibitors Market Outlook
- 7.3.2.1. Market Size & Forecast
- 7.3.2.2. Market Share & Forecast
- 7.3.2.2.1. By Type
- 7.3.2.2.2. By Drug
- 7.3.2.2.3. By Dosage Form
- 7.3.2.2.4. By Application
- 7.3.2.2.5. By End user
- 7.3.3. United Kingdom ACE Inhibitors Market Outlook
- 7.3.3.1. Market Size & Forecast
- 7.3.3.2. Market Share & Forecast
- 7.3.3.2.1. By Type
- 7.3.3.2.2. By Drug
- 7.3.3.2.3. By Dosage Form
- 7.3.3.2.4. By Application
- 7.3.3.2.5. By End user
- 7.3.4. Italy ACE Inhibitors Market Outlook
- 7.3.4.1. Market Size & Forecast
- 7.3.4.2. Market Share & Forecast
- 7.3.4.2.1. By Type
- 7.3.4.2.2. By Drug
- 7.3.4.2.3. By Dosage Form
- 7.3.4.2.4. By Application
- 7.3.4.2.5. By End user
- 7.3.5. Spain ACE Inhibitors Market Outlook
- 7.3.5.1. Market Size & Forecast
- 7.3.5.2. Market Share & Forecast
- 7.3.5.2.1. By Type
- 7.3.5.2.2. By Drug
- 7.3.5.2.3. By Dosage Form
- 7.3.5.2.4. By Application
- 7.3.5.2.5. By End user
8. Asia Pacific ACE Inhibitors Market Outlook
- 8.1. Market Size & Forecast
- 8.2. Market Share & Forecast
- 8.2.1. By Type
- 8.2.2. By Drug
- 8.2.3. By Dosage Form
- 8.2.4. By Application
- 8.2.5. By End user
- 8.2.6. By Country
- 8.3. Asia Pacific: Country Analysis
- 8.3.1. China ACE Inhibitors Market Outlook
- 8.3.1.1. Market Size & Forecast
- 8.3.1.2. Market Share & Forecast
- 8.3.1.2.1. By Type
- 8.3.1.2.2. By Drug
- 8.3.1.2.3. By Dosage Form
- 8.3.1.2.4. By Application
- 8.3.1.2.5. By End user
- 8.3.2. India ACE Inhibitors Market Outlook
- 8.3.2.1. Market Size & Forecast
- 8.3.2.2. Market Share & Forecast
- 8.3.2.2.1. By Type
- 8.3.2.2.2. By Drug
- 8.3.2.2.3. By Dosage Form
- 8.3.2.2.4. By Application
- 8.3.2.2.5. By End user
- 8.3.3. Japan ACE Inhibitors Market Outlook
- 8.3.3.1. Market Size & Forecast
- 8.3.3.2. Market Share & Forecast
- 8.3.3.2.1. By Type
- 8.3.3.2.2. By Drug
- 8.3.3.2.3. By Dosage Form
- 8.3.3.2.4. By Application
- 8.3.3.2.5. By End user
- 8.3.4. South Korea ACE Inhibitors Market Outlook
- 8.3.4.1. Market Size & Forecast
- 8.3.4.2. Market Share & Forecast
- 8.3.4.2.1. By Type
- 8.3.4.2.2. By Drug
- 8.3.4.2.3. By Dosage Form
- 8.3.4.2.4. By Application
- 8.3.4.2.5. By End user
- 8.3.5. Australia ACE Inhibitors Market Outlook
- 8.3.5.1. Market Size & Forecast
- 8.3.5.2. Market Share & Forecast
- 8.3.5.2.1. By Type
- 8.3.5.2.2. By Drug
- 8.3.5.2.3. By Dosage Form
- 8.3.5.2.4. By Application
- 8.3.5.2.5. By End user
9. Middle East & Africa ACE Inhibitors Market Outlook
- 9.1. Market Size & Forecast
- 9.2. Market Share & Forecast
- 9.2.1. By Type
- 9.2.2. By Drug
- 9.2.3. By Dosage Form
- 9.2.4. By Application
- 9.2.5. By End user
- 9.2.6. By Country
- 9.3. Middle East & Africa: Country Analysis
- 9.3.1. Saudi Arabia ACE Inhibitors Market Outlook
- 9.3.1.1. Market Size & Forecast
- 9.3.1.2. Market Share & Forecast
- 9.3.1.2.1. By Type
- 9.3.1.2.2. By Drug
- 9.3.1.2.3. By Dosage Form
- 9.3.1.2.4. By Application
- 9.3.1.2.5. By End user
- 9.3.2. UAE ACE Inhibitors Market Outlook
- 9.3.2.1. Market Size & Forecast
- 9.3.2.2. Market Share & Forecast
- 9.3.2.2.1. By Type
- 9.3.2.2.2. By Drug
- 9.3.2.2.3. By Dosage Form
- 9.3.2.2.4. By Application
- 9.3.2.2.5. By End user
- 9.3.3. South Africa ACE Inhibitors Market Outlook
- 9.3.3.1. Market Size & Forecast
- 9.3.3.2. Market Share & Forecast
- 9.3.3.2.1. By Type
- 9.3.3.2.2. By Drug
- 9.3.3.2.3. By Dosage Form
- 9.3.3.2.4. By Application
- 9.3.3.2.5. By End user
10. South America ACE Inhibitors Market Outlook
- 10.1. Market Size & Forecast
- 10.2. Market Share & Forecast
- 10.2.1. By Type
- 10.2.2. By Drug
- 10.2.3. By Dosage Form
- 10.2.4. By Application
- 10.2.5. By End user
- 10.2.6. By Country
- 10.3. South America: Country Analysis
- 10.3.1. Brazil ACE Inhibitors Market Outlook
- 10.3.1.1. Market Size & Forecast
- 10.3.1.2. Market Share & Forecast
- 10.3.1.2.1. By Type
- 10.3.1.2.2. By Drug
- 10.3.1.2.3. By Dosage Form
- 10.3.1.2.4. By Application
- 10.3.1.2.5. By End user
- 10.3.2. Colombia ACE Inhibitors Market Outlook
- 10.3.2.1. Market Size & Forecast
- 10.3.2.2. Market Share & Forecast
- 10.3.2.2.1. By Type
- 10.3.2.2.2. By Drug
- 10.3.2.2.3. By Dosage Form
- 10.3.2.2.4. By Application
- 10.3.2.2.5. By End user
- 10.3.3. Argentina ACE Inhibitors Market Outlook
- 10.3.3.1. Market Size & Forecast
- 10.3.3.2. Market Share & Forecast
- 10.3.3.2.1. By Type
- 10.3.3.2.2. By Drug
- 10.3.3.2.3. By Dosage Form
- 10.3.3.2.4. By Application
- 10.3.3.2.5. By End user
11. Market Dynamics
- 11.1. Drivers
- 11.2. Challenges
12. Market Trends & Developments
- 12.1. Merger & Acquisition (If Any)
- 12.2. Product Launches (If Any)
- 12.3. Recent Developments
13. Global ACE Inhibitors Market: SWOT Analysis
14. Porter's Five Forces Analysis
- 14.1. Competition in the Industry
- 14.2. Potential of New Entrants
- 14.3. Power of Suppliers
- 14.4. Power of Customers
- 14.5. Threat of Substitute Products
15. Competitive Landscape
- 15.1. Pfizer Inc
- 15.1.1. Business Overview
- 15.1.2. Products & Services
- 15.1.3. Recent Developments
- 15.1.4. Key Personnel
- 15.1.5. SWOT Analysis
- 15.2. Novartis AG
- 15.3. Johnson & Johnson
- 15.4. Merck KGaA
- 15.5. Sanofi S.A
- 15.6. Bayer AG
- 15.7. United Therapeutics Corporation
- 15.8. Teva Pharmaceutical Industry
- 15.9. Bristol-Myers Squibb
- 15.10. Takeda Pharmaceuticals Company
16. Strategic Recommendations
17. About Us & Disclaimer