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市場調查報告書
商品編碼
1841565
上游生物加工設備市場-全球產業規模、佔有率、趨勢、機會和預測,按產品類型、工作流程、最終用戶、地區和競爭細分,2020-2030 年預測Upstream Bioprocessing Equipment Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product Type, By Workflow, By End-User, By Region & Competition, 2020-2030F |
2024 年全球上游生物加工設備市場價值為 295.4 億美元,預計到 2030 年將達到 547.6 億美元,預測期內複合年成長率為 10.67%。
市場概況 | |
---|---|
預測期 | 2026-2030 |
2024年市場規模 | 295.4億美元 |
2030年市場規模 | 547.6億美元 |
2025-2030年複合年成長率 | 10.67% |
成長最快的領域 | 細胞分離 |
最大的市場 | 北美洲 |
上游生物加工設備市場是指生物製藥製造業的一個細分市場,專注於生物產品開發的初始階段,特別是細胞培養和發酵過程。這包括生物反應器、發酵槽、細胞培養基、過濾系統和混合系統等設備,這些設備對於培養用於生產生物製劑(包括疫苗、單株抗體、荷爾蒙和重組蛋白)的活細胞或微生物至關重要。
受全球對生物製藥、個人化醫療和生物相似藥需求激增的推動,生物製藥市場有望顯著成長。隨著慢性病和生活方式相關健康問題的日益普遍,對有效生物療法的需求也日益迫切,這推動了對上游生產能力的投資。此外,一次性生物反應器、自動化和連續生物製程等技術創新正在簡化生產流程,提高效率,並降低污染風險,而這些在無菌製藥環境中至關重要。
新興經濟體中合約製造組織和生物製藥公司的擴張也推動了市場成長,因為它們能夠以更低的營運成本獲得先進的製造基礎設施。此外,政府以資助生物製劑研究和生物製造基礎設施建設的形式提供的支持,也進一步刺激了產業擴張。此外,結合不銹鋼和一次性組件的混合生物處理系統的日益普及,提供了更大的靈活性和成本效益,對老牌企業和新創公司都具有吸引力。
隨著對工藝可擴展性和集約化的日益關注,以及監管部門對產品品質和工藝標準化的重視,預計將推動企業升級其上游加工能力。隨著生物製劑產品線的擴展和更複雜分子的開發,上游生物加工設備將在確保高產量和可重複生產方面發揮越來越重要的作用。因此,在技術進步、生物製劑產量成長以及對經濟高效且可擴展的生物製造解決方案的需求的推動下,預計上游生物加工設備市場將在已開發地區和發展中地區實現強勁成長。
生物製藥需求不斷成長
高昂的資本投資和營運成本
一次性技術在上游生物加工設備中的整合
Global Upstream Bioprocessing Equipment Market was valued at USD 29.54 billion in 2024 and is expected to reach USD 54.76 billion by 2030 with a CAGR of 10.67% during the forecast period.
Market Overview | |
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Forecast Period | 2026-2030 |
Market Size 2024 | USD 29.54 Billion |
Market Size 2030 | USD 54.76 Billion |
CAGR 2025-2030 | 10.67% |
Fastest Growing Segment | Cell Separation |
Largest Market | North America |
The Upstream Bioprocessing Equipment Market refers to the segment of the biopharmaceutical manufacturing industry that focuses on the initial phases of biological product development, particularly cell culture and fermentation processes. This includes equipment such as bioreactors, fermenters, cell culture media, filtration systems, and mixing systems that are essential for cultivating living cells or microorganisms used to produce biologics, including vaccines, monoclonal antibodies, hormones, and recombinant proteins.
The market is poised for significant growth driven by the surging global demand for biopharmaceuticals, personalized medicine, and biosimilars. As the prevalence of chronic diseases and lifestyle-related health issues increases, the need for effective biologic therapies is becoming more urgent, propelling investment in upstream manufacturing capacities. Furthermore, technological innovations such as single-use bioreactors, automation, and continuous bioprocessing are streamlining production workflows, enhancing efficiency, and reducing contamination risks, which are vital considerations in sterile pharmaceutical environments.
The expansion of contract manufacturing organizations and biopharmaceutical companies in emerging economies is also fueling market growth by enabling access to advanced manufacturing infrastructure at lower operational costs. In addition, government support in the form of funding for biologics research and biomanufacturing infrastructure development is further stimulating industry expansion. Moreover, increased adoption of hybrid bioprocessing systems that combine stainless steel and disposable components is offering greater flexibility and cost-efficiency, appealing to both established players and startups.
The growing focus on process scalability and intensification, along with regulatory emphasis on product quality and process standardization, is expected to push companies toward upgrading their upstream processing capabilities. As biologic pipelines expand and more complex molecules are developed, upstream bioprocessing equipment will play an increasingly critical role in ensuring high-yield and reproducible production. As a result, the upstream bioprocessing equipment market is anticipated to witness robust growth across developed and developing regions, driven by technological advancements, rising biologics production, and the need for cost-effective and scalable biomanufacturing solutions.
Key Market Drivers
Rising Demand for Biopharmaceuticals
The increasing global demand for biopharmaceuticals, such as monoclonal antibodies, vaccines, and gene therapies, is a primary driver for the Upstream Bioprocessing Equipment Market. The surge in chronic diseases like cancer, diabetes, and autoimmune disorders, coupled with an aging population, has escalated the need for advanced biologics. Upstream bioprocessing equipment, including bioreactors and cell culture systems, is critical for producing these complex therapies at scale.
Governments and healthcare organizations worldwide are prioritizing biopharmaceutical development to address public health challenges, particularly following global health crises like the COVID-19 pandemic, which highlighted the urgency for rapid vaccine production. The shift toward personalized medicine and targeted therapies further amplifies the demand for flexible and scalable bioprocessing solutions. Equipment such as single-use bioreactors enables manufacturers to meet diverse production needs while minimizing contamination risks.
Additionally, emerging markets in Asia-Pacific and Latin America are witnessing increased investments in biopharmaceutical infrastructure, driven by rising healthcare expenditures and growing prevalence of chronic conditions. The ability of upstream equipment to support high-yield cell cultures and recombinant protein production is vital for meeting this demand. As biopharmaceutical companies expand their pipelines to include novel biologics, the Upstream Bioprocessing Equipment Market is poised for sustained growth, fueled by the need for efficient, high-quality production systems that align with stringent regulatory standards and support global health initiatives.
In 2023, global biopharmaceutical production reached 1.2 million liters, with monoclonal antibodies accounting for 45% of output, per the International Federation of Pharmaceutical Manufacturers. Upstream equipment supported 60% of this capacity, with single-use systems contributing to 25% of production. In 2022, vaccine production surged by 30% globally, with bioreactors enabling 2 billion doses, addressing 15% of global demand, particularly in Asia-Pacific, where 200 new facilities were established.
Key Market Challenges
High Capital Investment and Operational Costs
One of the most significant challenges facing the upstream bioprocessing equipment market is the high capital investment required for the installation, commissioning, and validation of biomanufacturing infrastructure. Establishing a biologics manufacturing facility equipped with upstream processing equipment such as bioreactors, centrifuges, media preparation systems, and filtration units involves substantial upfront costs, which can be a barrier for small and mid-sized enterprises. In addition to equipment procurement, expenses related to facility design, utility setup, cleanroom construction, and compliance with regulatory requirements considerably increase the financial burden.
Moreover, the cost of operation is also high due to the need for specialized labor, ongoing maintenance, and frequent calibration of equipment to maintain sterility and productivity. Companies operating in this space must also invest significantly in workforce training and certification to ensure operational proficiency and quality control. While some larger biopharmaceutical companies can absorb these costs due to their expansive budgets and economies of scale, emerging firms and startups often face difficulties in securing adequate funding.
This financial barrier may hinder innovation and delay the time-to-market for critical biologics, especially in regions where public and private investment in biomanufacturing is still limited. The high cost of implementing advanced technologies such as automation, real-time monitoring systems, and single-use components further exacerbates the challenge, particularly for firms seeking cost-efficiency in production.
As the demand for scalable and flexible production systems increases, stakeholders in the upstream bioprocessing equipment market must explore alternative funding models, government grants, and collaborative partnerships to overcome the financial constraints associated with capital investment and operational expenses.
Key Market Trends
Integration of Single-Use Technologies in Upstream Bioprocessing Equipment
The global Upstream Bioprocessing Equipment Market is witnessing a transformative shift with the rapid integration of single-use technologies in bioprocessing workflows. Single-use systems, which include bioreactors, mixers, tubing, and filtration units, are increasingly replacing traditional stainless-steel systems. This trend is particularly driven by the advantages these technologies offer in terms of operational flexibility, reduced contamination risk, and shorter turnaround time between production cycles. In research and development environments, as well as early-phase biologics manufacturing, single-use systems facilitate faster experimentation and scale-up processes without the extensive cleaning and validation requirements of reusable equipment.
Pharmaceutical and biotechnology companies are investing heavily in modular single-use platforms that enable rapid configuration and adjustment based on batch size or biologic type. These platforms allow for high levels of customization, making them suitable for the production of personalized medicines and monoclonal antibodies. Additionally, the reduced capital investment needed for single-use systems appeals to emerging biopharmaceutical firms and contract manufacturing organizations.
Environmental concerns associated with disposability are being addressed through improved material science, with manufacturers developing recyclable or biodegradable single-use components. The growing acceptance of these sustainable options is further accelerating adoption. Regulatory bodies are also becoming more familiar with single-use equipment validation protocols, contributing to their widespread market integration.
As a result, single-use technologies are transforming upstream operations by simplifying workflows, minimizing cross-contamination, and enabling rapid bioprocessing innovation, thereby contributing significantly to the growth of the Upstream Bioprocessing Equipment Market.
In this report, the Global Upstream Bioprocessing Equipment Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:
Company Profiles: Detailed analysis of the major companies present in the Global Upstream Bioprocessing Equipment Market.
Global Upstream Bioprocessing Equipment Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report: