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穩定同位素標記化合物市場 - 2018-2028F 全球產業規模、佔有率、趨勢、機會和預測，按化合物、應用、物質、適應症、方法、最終用戶、地區細分和競爭
市場調查報告書
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1348845

穩定同位素標記化合物市場 - 2018-2028F 全球產業規模、佔有率、趨勢、機會和預測，按化合物、應用、物質、適應症、方法、最終用戶、地區細分和競爭

Stable Isotopes Labeled Compounds Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028F Segmented By Compounds, By Application, By Substances, By Indication, By Method, By End-User, By Region and Competition
出版日期: | 出版商: TechSci Research | 英文 119 Pages | 商品交期: 2-3個工作天內

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簡介目錄

預計2024年至2028年預測期內，全球穩定同位素標記化合物市場將以顯著速度成長。穩定同位素廣泛用於環境研究，例如追蹤污染物來源和研究氣候變遷。對環境研究不斷成長的需求預計將推動穩定同位素標記化合物市場的成長。例如，穩定同位素標記的化合物用於研究碳循環和人類活動對環境的影響。隨著環境研究的需求不斷增加，對穩定同位素標記化合物的需求也預計會成長。

新藥和療法的需求不斷增加

市場概況
預測期 2024-2028
2022年市場規模 30103萬美元
2028年市場規模 37626萬美元
CAGR (2023-2028) 3.7%
成長最快的細分市場 製藥與生物技術公司
最大的市場 北美洲

由於癌症、心血管疾病和糖尿病等慢性疾病盛行率的上升，對新藥和新療法的需求不斷增加。根據世界衛生組織 (WHO) 的資料，癌症是全世界死亡的主要因素之一，2020年約有 1,000 萬人因癌症死亡，約佔死亡人數的六分之一。最常見的癌症是肺癌、乳癌、結腸癌、直腸癌、攝護腺癌。根據美國癌症協會2022年發布的報告資料，2022年美國新增癌症病例超過 191 萬例。新增病例分別為 395,600 例和 343,040 例，預計生殖系統和消化系統惡性腫瘤將佔癌症病例的大多數。根據 PubMed 於2021年 8月發布的資料，穩定同位素示蹤是了解營養保健品影響和標靶癌症代謝的分子機制的重要方法。

穩定同位素標記的化合物使研究人員能夠以無與倫比的精確度研究藥物代謝和潛在毒性。透過將標記化合物放入候選藥物中，科學家可以追蹤其分解並識別代謝物。這些知識對於預測藥物間相互作用、評估潛在的副作用以及設計提高生物利用度和降低毒性的藥物非常重要。

此外，穩定同位素標記的化合物為藥物在人體內的吸收、分佈、代謝和排泄 (ADME) 提供了有價值的見解。透過在藥物開發過程中引進標記化合物，研究人員可以追蹤其命運、闡明代謝途徑並評估藥物清除效率。這些資訊有助於最佳化藥物劑量、最大限度地減少潛在副作用並提高整體藥物安全性。

穩定同位素標記的化合物是在其化學結構中摻入一種或多種穩定同位素（例如碳 13、氮 15 和氧 18）的合成分子。

在藥物發現和開發中使用穩定同位素標記的化合物有幾個優點。首先，穩定同位素是非放射性的，這使其在實驗中處理和使用更安全。其次，穩定同位素在化學上與未標記的同位素相同，這意味著它們在生物系統中的行為是相同的。這使得研究人員能夠更準確地研究藥物對身體的影響。最後，穩定同位素標記提供了一種追蹤藥物在體內的命運的獨特方法，這對於了解其藥物動力學和最佳化其劑量非常重要。

穩定同位素標記的化合物也用於臨床前研究，以研究新藥的藥物動力學和毒理學。這些研究對於獲得新藥監管部門的批准非常重要。

人們對蛋白質體學和代謝組學的興趣日益濃厚

蛋白質體學和代謝組學是生命科學中兩個快速發展的領域，有可能徹底改變我們對生物系統的理解，並為多種疾病開發新療法。這些領域嚴重依賴穩定同位素標記化合物的使用，這些化合物是在其化學結構中摻入一種或多種穩定同位素（例如碳 13、氮 15 和氧 18）的合成分子。人們對蛋白質體學和代謝組學的興趣日益濃厚，推動了全球穩定同位素標記化合物市場的成長，因為這些化合物在這些領域中發揮著非常重要的作用。例如，它們是穩定同位素標記技術的一部分，例如細胞培養中氨基酸穩定同位素標記 (SILAC) 和同位素編碼親和標籤 (ICAT)。穩定同位素標記在轉譯後修飾(PTM) 的研究中也發揮著非常重要的作用，這對於蛋白質功能和調節非常重要。蛋白質體學是蛋白質體的研究，蛋白質體是由細胞、組織或生物體產生的整套蛋白質。蛋白質體學研究包括蛋白質的鑑定、定量和表徵及其與其他分子的相互作用。蛋白質體學研究可以深入了解疾病的分子機制，並確定藥物開發的新標靶。穩定同位素標記的化合物用於蛋白質體學研究，以研究蛋白質週轉、蛋白質-蛋白質相互作用和蛋白質定位。

代謝組學是對代謝組的研究，代謝組是細胞、組織或生物體產生的整套小分子。代謝組學研究包括代謝物的鑑定、定量和表徵及其與其他分子的相互作用。穩定同位素標記的化合物用於代謝組學研究，以研究代謝通量、代謝途徑和代謝調節。

穩定同位素標記的化合物對於許多蛋白質體學和代謝組學應用非常重要。例如，穩定同位素標記的氨基酸用於定量蛋白質組學實驗，以比較不同樣本之間的蛋白質表現量。穩定同位素標記的脂質和碳水化合物用於代謝組學實驗，以研究代謝途徑和代謝通量。穩定同位素標記的核苷酸用於核酸定序實驗，以提高準確性並減少錯誤。

對個人化藥物和精準藥物日益成長的興趣也推動了全球穩定同位素標記化合物市場的成長。個人化醫療和精準醫療目的是開發適合個人基因組成、生活方式和環境的治療方法。蛋白質體學和代謝組學研究可以為開發個人化和精準醫學治療提供有價值的資訊。穩定同位素標記的化合物對於許多此類應用非常重要。

技術進步

技術進步推動許多產業的發展，全球穩定同位素標記化合物市場也不例外。

推動穩定同位素標記化合物市場成長的關鍵技術進步之一是新標記技術的開發。傳統的標記技術，如同位素交換和化學合成，既耗時又昂貴，並且需要專門的設備。然而，新的標記技術，例如代謝標記、酵素標記和雙正交標記，更有效率、更具成本效益，並且可以用於更廣泛的應用。

代謝標記是一種包括將穩定同位素標記的前體（例如胺基酸、核苷酸或糖）摻入活細胞或生物體中的技術。然後將這些前驅物摻入蛋白質、核酸或其他生物分子中，在體內產生穩定的同位素標記化合物。代謝標記是研究代謝途徑、蛋白質週轉和蛋白質-蛋白質相互作用的強大技術。

酶標記是一種包括使用酶選擇性地將穩定同位素標記的底物摻入特定生物分子的技術。例如，蛋白酶可用於選擇性地將穩定同位素標記的胺基酸摻入特定蛋白質中，產生位點特異性標記的蛋白質。酵素標記是研究蛋白質功能、蛋白質-蛋白質相互作用和轉譯後修飾的強大技術。

生物正交標記是一種包括使用非天然化學反應選擇性標記生物分子的技術。例如，雙正交反應可用於選擇性地將穩定同位素標記的糖摻入特定的醣蛋白中，產生位點特異性標記的醣蛋白。生物正交標記是研究複雜生物分子（例如糖蛋白）以及開發新的診斷和治療劑的強大技術。

推動全球穩定同位素標記化合物市場成長的另一項技術進步是新分析技術的開發。質譜和核磁共振 (NMR) 光譜等分析技術對於分析穩定同位素標記的化合物及其與其他分子的相互作用非常重要。採用高解析度質譜和核磁共振波譜等新分析技術，可生產高品質、高通量和高解析度的穩定同位素標記化合物。

高解析度質譜是一種可用於精確測量穩定同位素標記化合物的質荷比的技術，可以對這些化合物進行識別和定量。高解析度質譜是研究蛋白質表現、代謝途徑和代謝通量的強大技術。

核磁共振波譜是一種可用於確定穩定同位素標記化合物的3D結構及其與其他分子相互作用的技術。核磁共振波譜是研究蛋白質-蛋白質相互作用、蛋白質-配體相互作用和蛋白質-核酸相互作用的強大技術。

最近的發展

  • 2022年 10月，Oak Ridge National Laboratory (ORNL) 宣布將協助建造新設施，生產用於包括醫藥在內的多種行業的同位素。
  • 由於 Cambridge Isotope Laboratories Inc. (CIL) 和 ISOtopic Solutions 之間的合作，新型穩定同位素標記和未標記的粗脂質酵母萃取物於2022年 9月上市。
  • Cambridge Isotope Laboratories Inc.(CIL) 於2021年7月發布了首款商用的用於量子應用的富含12C 的甲烷級氣體，該實驗室是Otsuka Group的成員，也是世界領先的穩定同位素和穩定同位素標記化學品生產商。
  • 2020年，Cambridge Isotope Laboratories (CIL) 宣布推出一系列新的穩定同位素標記化合物用於藥物開發。此系列包括常用藥物的氘標記類似物，例如布洛芬和萘普生，目的是提高藥物療效並降低毒性。這些化合物在開發一系列疾病的新療法方面具有潛在的應用。
  • 2020年，Glasgow大學的一組研究人員開發了一種新的穩定同位素標記化合物，用於分析檸檬酸循環（關鍵的代謝途徑）。
  • 2020年， Isotope Technologies Garching（ITG）宣布與德國癌症研究中心（DKFZ）建立合作關係，開發用於癌症診斷和治療的新型放射性藥物。

市場區隔

全球穩定同位素標記化合物市場按化合物、應用、物質、適應症、方法、最終用戶、地區和公司細分。依化合物，市場可分為碳（13C）、氮（15N）、氘、氧（18O）等。根據應用，市場可分為診斷、藥物發現、影像、滅菌等。根據物質，市場可分為核酸、胺基酸、藥物/代謝物、脂肪酸/脂質、核磁共振溶劑等。根據適應症，市場可以進一步細分為心臟病學、神經學、發炎、代謝疾病等。根據方法，市場可分為化學和細胞培養。根據最終用戶，市場可分為製藥和生技公司、學術機構等。

市場參與者

全球穩定同位素標記化合物市場的主要參與者包括 PerkinElmer Inc.、Merck KGaA、3M Company、Cambridge Isotope Laboratories, Inc.、JSC Isotope、Creative Proteomics、Medical Isotopes, Inc.、Omicron Biochemicals, Inc.、Trace Sciences International、Nippon Sanso Holdings Corporation。

報告範圍：

在本報告中，除了以下詳細介紹的產業趨勢外，全球穩定同位素標記化合物市場也分為以下幾類：

穩定同位素標記化合物市場（依化合物）：

  • 碳 (13C)
  • 氮氣(15N)
  • 氘
  • 氧氣(18O)
  • 其他

穩定同位素標記化合物市場，按應用：

  • 診斷
  • 藥物發現
  • 影像學
  • 消毒
  • 其他

穩定同位素標記化合物市場，依物質分類：

  • 核酸
  • 胺基酸
  • 藥物/代謝物
  • 脂肪酸/脂質
  • 核磁共振溶劑
  • 其他

穩定同位素標記化合物市場，依適應症分類：

  • 心臟病學
  • 神經病學
  • 發炎
  • 代謝性疾病
  • 其他

穩定同位素標記化合物市場，依方法分類：

  • 化學
  • 細胞培養

穩定同位素標記化合物市場，依最終用戶分類：

  • 製藥和生物技術公司
  • 學術機構
  • 其他

穩定同位素標記化合物市場，按地區：

  • 亞太
    • 中國
    • 印度
    • 日本
    • 韓國
    • 澳洲
  • 歐洲
    • 法國
    • 德國
    • 英國
    • 義大利
    • 西班牙
  • 北美洲
    • 美國
    • 墨西哥
    • 加拿大
  • 南美洲
    • 巴西
    • 阿根廷
    • 哥倫比亞
  • 中東和非洲
    • 南非
    • 沙烏地阿拉伯
    • 阿拉伯聯合大公國

競爭格局

公司簡介：對全球穩定同位素標記化合物市場中主要公司的詳細分析。

可用的客製化：

根據給定的市場資料，TechSci Research 可根據公司的具體需求提供客製化服務。本報告可以使用以下自訂選項：

公司資訊

  • 其他市場參與者（最多五個）的詳細分析和概況分析。

目錄

第1章 產品概述

  • 市場定義
  • 市場範圍
    • 涵蓋的市場
    • 研究年份
    • 主要市場區隔

第2章 研究方法

  • 研究目的
  • 基線方法
  • 主要產業夥伴
  • 主要協會和二手資料來源
  • 預測方法
  • 資料三角測量與驗證
  • 假設和限制

第3章 執行摘要

  • 市場概況
  • 主要市場細分概述
  • 主要市場參與者概述
  • 重點地區/國家概況
  • 市場促進因素、挑戰、趨勢概述

第4章 客戶之聲

第5章 全球穩定同位素標記化合物市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 依化合物分類（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按應用（診斷、藥物發現、影像、滅菌、其他）
    • 依物質（核酸、胺基酸、藥物/代謝物、脂肪酸/脂質、NMR 溶劑等）
    • 按適應症（心臟科、神經學、發炎、代謝疾病等）
    • 依方法（化學、細胞培養）
    • 按最終用戶（製藥和生物技術公司、學術機構等）
    • 按地區
    • 按公司分類 (2022)
  • 市場地圖
    • 按化合物分類
    • 按應用
    • 按物質分類
    • 按指示
    • 依方法
    • 按最終用戶

第6章 亞太地區穩定同位素標記化合物市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 依化合物分類（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按應用（診斷、藥物發現、影像、滅菌、其他）
    • 依物質（核酸、胺基酸、藥物/代謝物、脂肪酸/脂質、NMR 溶劑等）
    • 按適應症（心臟科、神經學、發炎、代謝疾病等）
    • 依方法（化學、細胞培養）
    • 按最終用戶（製藥和生物技術公司、學術機構等）
    • 按國家
  • 亞太地區：國家分析
    • 中國
    • 印度
    • 日本
    • 韓國
    • 澳洲

第7章 歐洲穩定同位素標記化合物市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 依化合物分類（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按應用（診斷、藥物發現、影像、滅菌、其他）
    • 依物質（核酸、胺基酸、藥物/代謝物、脂肪酸/脂質、NMR 溶劑等）
    • 按適應症（心臟科、神經學、發炎、代謝疾病等）
    • 依方法（化學、細胞培養）
    • 按最終用戶（製藥和生物技術公司、學術機構等）
    • 按國家
  • 歐洲：國家分析
    • 法國
    • 德國
    • 英國
    • 義大利
    • 西班牙

第8章 北美穩定同位素標記化合物市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 依化合物分類（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按應用（診斷、藥物發現、影像、滅菌、其他）
    • 依物質（核酸、胺基酸、藥物/代謝物、脂肪酸/脂質、NMR 溶劑等）
    • 按適應症（心臟科、神經學、發炎、代謝疾病等）
    • 依方法（化學、細胞培養）
    • 按最終用戶（製藥和生物技術公司、學術機構等）
    • 按國家
  • 北美：國家分析
    • 美國
    • 墨西哥
    • 加拿大

第9章 南美洲穩定同位素標記化合物市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 依化合物分類（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按應用（診斷、藥物發現、影像、滅菌、其他）
    • 依物質（核酸、胺基酸、藥物/代謝物、脂肪酸/脂質、NMR 溶劑等）
    • 按適應症（心臟科、神經學、發炎、代謝疾病等）
    • 依方法（化學、細胞培養）
    • 按最終用戶（製藥和生物技術公司、學術機構等）
    • 按國家
  • 南美洲：國家分析
    • 巴西
    • 阿根廷
    • 哥倫比亞

第10章 中東和非洲穩定同位素標記化合物市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 依化合物分類（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按應用（診斷、藥物發現、影像、滅菌、其他）
    • 依物質（核酸、胺基酸、藥物/代謝物、脂肪酸/脂質、NMR 溶劑等）
    • 按適應症（心臟科、神經學、發炎、代謝疾病等）
    • 依方法（化學、細胞培養）
    • 按最終用戶（製藥和生物技術公司、學術機構等）
    • 按國家
  • MEA：國家分析
    • 南非穩定同位素標記化合物
    • 沙烏地阿拉伯穩定同位素標記化合物
    • 阿拉伯聯合大公國穩定同位素標記化合物

第11章 市場動態

  • 動力
  • 挑戰

第12章 市場趨勢與發展

  • 併購
  • 產品發布
  • 技術進步

第13章 競爭格局

  • 商業概覽
  • 公司概況
  • 產品與服務
  • 財務（據報導）
  • 最近的發展
  • SWOT分析
    • PerkinElmer Inc.
    • Merck KGaA
    • 3M Company
    • Cambridge Isotope Laboratories, Inc.
    • JSC Isotope
    • Creative Proteomics
    • Medical Isotopes, Inc.
    • Omicron Biochemicals, Inc.
    • Trace Sciences International
    • Nippon Sanso Holdings Corporation

第14章 策略建議

簡介目錄
Product Code: 4565

Global stable isotopes labeled compounds market is expected to grow at a significant rate during the forecast period 2024-2028. Stable isotopes are extensively used in environmental studies, such as tracing the sources of pollutants and studying climate change. The growing demand for environmental studies is expected to drive the growth of the stable isotopes labeled compounds market. For example, stable isotope labeled compounds are used to study the carbon cycle and the impact of human activities on the environment. As the demand for environmental studies continues to increase, the demand for stable isotopes labeled compounds is expected to grow.

Stable isotopes are non-radioactive isotopes that have the same number of protons but different numbers of neutrons in their atomic nuclei. They are used extensively in a wide range of scientific and industrial applications, including research, medicine, agriculture, and environmental studies. Stable isotopes labeled compounds are synthetic molecules that incorporate one or more stable isotopes, often carbon-13, nitrogen-15, and oxygen-18, into their chemical structure. These labeled compounds are used to investigate metabolic pathways, study protein-protein interactions, and develop new drugs, which will propel the global stable isotopes labeled compounds market.

Increasing Demand for New Drugs and Therapies

Market Overview
Forecast Period2024-2028
Market Size 2022USD 301.03 Million
Market Size 2028USD 376.26 Million
CAGR (2023-2028)3.7%
Fastest Growing SegmentPharmaceutical & Biotechnology Companies
Largest MarketNorth America

The demand for new drugs and therapies is constantly increasing, driven by the rising prevalence of chronic diseases such as cancer, cardiovascular diseases, and diabetes. According to the World Health Organization (WHO), cancer is a major factor for the cause of death across the world, accounting for approximately 10 million deaths in 2020, or about one in six deaths. The most common cancers are lung, breast, colon and rectum, and prostate cancers. There were over 1.91 million new cancer cases in the United States in 2022, according to data from the American Cancer Society report, publsihed in 2022. With 395,600 and 343,040 new cases, respectively, it is anticipated that malignancies of the genital and digestive systems will account for the majority of cancer cases. Stable isotope tracing is a crucial method for understanding the molecular mechanisms by which nutraceuticals affect and target cancer metabolism, according to data that was published by PubMed in August 2021.

Stable isotopes labeled compounds enable researchers to study drug metabolism and potential toxicity with unparalleled precision. By putting a labeled compound into a drug candidate, scientists can track its breakdown and identify metabolites. This knowledge is crucial in predicting drug-drug interactions, evaluating potential adverse effects, and designing drugs with improved bioavailability and reduced toxicity.

Moreover, stable isotopes labeled compounds offer valuable insights into the absorption, distribution, metabolism, and excretion (ADME) of drugs in the human body. By introducing a labeled compound during drug development, researchers can track its fate, elucidate metabolic pathways, and assess the efficiency of drug clearance. This information aids in optimizing drug dosage, minimizing potential side effects, and improving overall drug safety.

Stable isotope labeled compounds are synthetic molecules that incorporate one or more stable isotopes, such as carbon-13, nitrogen-15, and oxygen-18, into their chemical structure.

The use of stable isotope labeled compounds in drug discovery and development has several advantages. Firstly, stable isotopes are non-radioactive, which makes them safer to handle and use in experiments. Secondly, stable isotopes are chemically identical to their non-labeled counterparts, which means that their behavior in biological systems is the same. This allows researchers to study the effects of drugs on the body more accurately. Finally, stable isotope labeling provides a unique way to track the fate of a drug in the body, which is essential for understanding its pharmacokinetics and optimizing its dosage.

Stable isotope labeled compounds are also used in preclinical studies to investigate the pharmacokinetics and toxicology of new drugs. These studies are essential for obtaining regulatory approval for new drugs.

Growing Interest in Proteomics and Metabolomics

Proteomics and metabolomics are two rapidly growing fields in life sciences that have the potential to revolutionize our understanding of biological systems and develop new therapies for a wide range of diseases. These fields rely heavily on the use of stable isotope labeled compounds, which are synthetic molecules that incorporate one or more stable isotopes, such as carbon-13, nitrogen-15, and oxygen-18, into their chemical structure. The growing interest in proteomics and metabolomics is driving the growth of the global stable isotopes labeled compounds market, as these compounds play a crucial role in these fields. For example, they are a part of stable isotope labeling techniques, such as Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) and Isotope-Coded Affinity Tag (ICAT). Stable isotope labeling also plays a crucial role in studying Post-Translational Modifications (PTMs), which are essential for protein functionality and regulation. Proteomics is the study of the proteome, which is the entire set of proteins produced by a cell, tissue, or organism. Proteomics research involves the identification, quantification, and characterization of proteins and their interactions with other molecules. Proteomics research can provide insights into the molecular mechanisms underlying diseases and identify new targets for drug development. Stable isotopes labeled compounds are used in proteomics research to study protein turnover, protein-protein interactions, and protein localization.

Metabolomics is the study of the metabolome, which is the entire set of small molecules produced by a cell, tissue, or organism. Metabolomics research involves the identification, quantification, and characterization of metabolites and their interactions with other molecules. Stable isotopes labeled compounds are used in metabolomics research to study metabolic flux, metabolic pathways, and metabolic regulation.

Stable isotopes labeled compounds are essential for many proteomics and metabolomics applications. For example, stable isotope labeled amino acids are used in quantitative proteomics experiments to compare protein expression levels between different samples. Stable isotope labeled lipids and carbohydrates are used in metabolomics experiments to study metabolic pathways and metabolic flux. Stable isotope labeled nucleotides are used in nucleic acid sequencing experiments to improve accuracy and reduce errors.

The growing interest in personalized medicines and precision medicines is also driving the growth of the global stable isotopes labeled compounds market. Personalized medicine and precision medicine aim to develop treatments that are tailored to an individual's genetic makeup, lifestyle, and environment. Proteomics and metabolomics research can provide valuable information for developing personalized and precision medicine treatments. Stable isotope labeled compounds are essential for many of these applications.

Technological Advancements

Technological advancements are driving the growth of many industries, and the global stable isotopes labeled compounds market is no exception.

One of the key technological advancements driving the growth of the stable isotopes labeled compounds market is the development of new labeling techniques. Traditional labeling techniques, such as isotopic exchange and chemical synthesis, are time-consuming, expensive, and require specialized equipment. However, new labeling techniques, such as metabolic labeling, enzymatic labeling, and biorthogonal labeling, are more efficient, cost-effective, and can be used in a wider range of applications.

Metabolic labeling is a technique that involves incorporating stable isotope labeled precursors, such as amino acids, nucleotides, or sugars, into living cells or organisms. These precursors are then incorporated into proteins, nucleic acids, or other biomolecules, allowing for the production of stable isotope labeled compounds in vivo. Metabolic labeling is a powerful technique for studying metabolic pathways, protein turnover, and protein-protein interactions.

Enzymatic labeling is a technique that involves using enzymes to selectively incorporate stable isotope labeled substrates into specific biomolecules. For example, a protease enzyme can be used to selectively incorporate stable isotope labeled amino acids into specific proteins, allowing for the production of site-specifically labeled proteins. Enzymatic labeling is a powerful technique for studying protein function, protein-protein interactions, and post-translational modifications.

Biorthogonal labeling is a technique that involves using non-natural chemical reactions to selectively label biomolecules. For example, a biorthogonal reaction can be used to selectively incorporate stable isotope labeled sugars into specific glycoproteins, allowing for the production of site-specifically labeled glycoproteins. Biorthogonal labeling is a powerful technique for studying complex biomolecules, such as glycoproteins, and for developing new diagnostic and therapeutic agents.

Another technological advancement driving the growth of the global stable isotopes labeled compounds market is the development of new analytical techniques. Analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, are essential for analyzing stable isotope labeled compounds and their interactions with other molecules. The adoption of new analytical techniques, such as high-resolution mass spectrometry and NMR spectroscopy, is enabling the production of high-quality, high-throughput, and high-resolution stable isotope labeled compounds.

High-resolution mass spectrometry is a technique that can be used to accurately measure the mass-to-charge ratio of stable isotope labeled compounds, allowing for the identification and quantification of these compounds. High-resolution mass spectrometry is a powerful technique for studying protein expression, metabolic pathways, and metabolic flux.

Nuclear magnetic resonance spectroscopy is a technique that can be used to determine the three-dimensional structure of stable isotope labeled compounds and their interactions with other molecules. NMR spectroscopy is a powerful technique for studying protein-protein interactions, protein-ligand interactions, and protein-nucleic acid interactions.

Recent Developments

  • In October 2022, Oak Ridge National Laboratory (ORNL) announced that it would contribute to the construction of new facilities to produce isotopes used in a variety of industries, including medicine.
  • The novel stable isotope-labeled and unlabeled Crude Lipid Yeast Extract was made available in September 2022, thanks to a collaboration between Cambridge Isotope Laboratories Inc. (CIL) and ISOtopic Solutions.
  • The first commercially accessible 12C-enriched methane-grade gas for quantum applications was released by Cambridge Isotope Laboratories, Inc. (CIL), a member of the Otsuka Group and the world's leading producer of stable isotopes and stable isotope-labeled chemicals, in July 2021.
  • In 2020, Cambridge Isotope Laboratories (CIL) announced the launch of a new range of stable isotope labeled compounds for drug development. This range includes deuterium-labeled analogs of commonly used drugs, such as ibuprofen and naproxen, which are designed to improve drug efficacy and reduce toxicity. These compounds have potential applications in the development of new therapeutics for a range of diseases.
  • In 2020, a team of researchers from the University of Glasgow developed a new stable isotope labeled compound for the analysis of the citric acid cycle, a key metabolic pathway.
  • In 2020, Isotope Technologies Garching (ITG) announced a partnership with the German Cancer Research Center (DKFZ) to develop new radiopharmaceuticals for cancer diagnosis and treatment.

Market Segmentation

The global stable isotopes labeled compounds market is segmented by compounds, application, substances, indication, method, end-user, region and company. Based on compounds, the market can be segmented into carbon (13C), nitrogen(15N), deuterium, oxygen(18O), and others. On the basis of application, the market can be categorized as diagnosis, drug discovery, imaging, sterilization, and others. Based on substances, the market can be fragmented into nucleic acids, amino acids, drugs/metabolites, fatty acids /lipids, NMR solvents and others. On the basis of indication, the market can be further segmented into cardiology, neurology, inflammation, metabolic disease, and others. Based on method, the market can be split into chemical and cell-culturing. On the basis of end-user, the market can be categorized into pharmaceutical and biotechnology companies, academic institutes, and others.

Market Players

Major players of the global stable isotopes labeled compounds market include PerkinElmer Inc., Merck KGaA, 3M Company, Cambridge Isotope Laboratories, Inc., JSC Isotope, Creative Proteomics, Medical Isotopes, Inc., Omicron Biochemicals, Inc., Trace Sciences International, and Nippon Sanso Holdings Corporation.

Report Scope:

In this report, global stable isotopes labeled compounds market has been segmented into following categories, in addition to the industry trends which have also been detailed below:

Stable Isotopes Labeled Compounds Market, By Compounds:

  • Carbon (13C)
  • Nitrogen(15N)
  • Deuterium
  • Oxygen(18O)
  • Others

Stable Isotopes Labeled Compounds Market, By Application:

  • Diagnosis
  • Drug Discovery
  • Imaging
  • Sterilization
  • Others

Stable Isotopes Labeled Compounds Market, By Substances:

  • Nucleic Acids
  • Amino Acids
  • Drugs/Metabolites
  • Fatty Acids/Lipids
  • NMR Solvents
  • Others

Stable Isotopes Labeled Compounds Market, By Indication:

  • Cardiology
  • Neurology
  • Inflammation
  • Metabolic Disease
  • Others

Stable Isotopes Labeled Compounds Market, By Method:

  • Chemical
  • Cell-culturing

Stable Isotopes Labeled Compounds Market, By End-User:

  • Pharmaceutical and Biotechnology Companies
  • Academic Institute
  • Others

Stable Isotopes Labeled Compounds Market, By Region:

  • Asia-Pacific
    • China
    • India
    • Japan
    • South Korea
    • Australia
  • Europe
    • France
    • Germany
    • United Kingdom
    • Italy
    • Spain
  • North America
    • United States
    • Mexico
    • Canada
  • South America
    • Brazil
    • Argentina
    • Colombia
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the global stable isotopes labeled compounds market.

Available Customizations:

With the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

  • Detailed analysis and profiling of additional market players (up to five).

Table of Contents

1. Product Overview

  • 1.1. Market Definition
  • 1.2. Scope of the Market
    • 1.2.1. Markets Covered
    • 1.2.2. Years Considered for Study
    • 1.2.3. Key Market Segmentations

2. Research Methodology

  • 2.1. Objective of the Study
  • 2.2. Baseline Methodology
  • 2.3. Key Industry Partners
  • 2.4. Major Association and Secondary Sources
  • 2.5. Forecasting Methodology
  • 2.6. Data Triangulation & Validation
  • 2.7. Assumptions and Limitations

3. Executive Summary

  • 3.1. Overview of the Market
  • 3.2. Overview of Key Market Segmentations
  • 3.3. Overview of Key Market Players
  • 3.4. Overview of Key Regions/Countries
  • 3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Stable Isotopes Labeled Compounds Market Outlook

  • 5.1. Market Size & Forecast
    • 5.1.1. By Value
  • 5.2. Market Share & Forecast
    • 5.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 5.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 5.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 5.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 5.2.5. By Method (Chemical, Cell-culturing)
    • 5.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 5.2.7. By Region
    • 5.2.8. By Company (2022)
  • 5.3. Market Map
    • 5.3.1. By Compounds
    • 5.3.2. By Application
    • 5.3.3. By Substances
    • 5.3.4. By Indication
    • 5.3.5. By Method
    • 5.3.6. By End-User

6. Asia-Pacific Stable Isotopes Labeled Compounds Market Outlook

  • 6.1. Market Size & Forecast
    • 6.1.1. By Value
  • 6.2. Market Share & Forecast
    • 6.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 6.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 6.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 6.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 6.2.5. By Method (Chemical, Cell-culturing)
    • 6.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 6.2.7. By Country
  • 6.3. Asia-Pacific: Country Analysis
    • 6.3.1. China Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.1.1. Market Size & Forecast
        • 6.3.1.1.1. By Value
      • 6.3.1.2. Market Share & Forecast
        • 6.3.1.2.1. By Compounds
        • 6.3.1.2.2. By Application
        • 6.3.1.2.3. By Substances
        • 6.3.1.2.4. By Indication
        • 6.3.1.2.5. By Method
        • 6.3.1.2.6. By End-User
    • 6.3.2. India Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.2.1. Market Size & Forecast
        • 6.3.2.1.1. By Value
      • 6.3.2.2. Market Share & Forecast
        • 6.3.2.2.1. By Compounds
        • 6.3.2.2.2. By Application
        • 6.3.2.2.3. By Substances
        • 6.3.2.2.4. By Indication
        • 6.3.2.2.5. By Method
        • 6.3.2.2.6. By End-User
    • 6.3.3. Japan Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.3.1. Market Size & Forecast
        • 6.3.3.1.1. By Value
      • 6.3.3.2. Market Share & Forecast
        • 6.3.3.2.1. By Compounds
        • 6.3.3.2.2. By Application
        • 6.3.3.2.3. By Substances
        • 6.3.3.2.4. By Indication
        • 6.3.3.2.5. By Method
        • 6.3.3.2.6. By End-User
    • 6.3.4. South Korea Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.4.1. Market Size & Forecast
        • 6.3.4.1.1. By Value
      • 6.3.4.2. Market Share & Forecast
        • 6.3.4.2.1. By Compounds
        • 6.3.4.2.2. By Application
        • 6.3.4.2.3. By Substances
        • 6.3.4.2.4. By Indication
        • 6.3.4.2.5. By Method
        • 6.3.4.2.6. By End-User
    • 6.3.5. Australia Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.5.1. Market Size & Forecast
        • 6.3.5.1.1. By Value
      • 6.3.5.2. Market Share & Forecast
        • 6.3.5.2.1. By Compounds
        • 6.3.5.2.2. By Application
        • 6.3.5.2.3. By Substances
        • 6.3.5.2.4. By Indication
        • 6.3.5.2.5. By Method
        • 6.3.5.2.6. By End-User

7. Europe Stable Isotopes Labeled Compounds Market Outlook

  • 7.1. Market Size & Forecast
    • 7.1.1. By Value
  • 7.2. Market Share & Forecast
    • 7.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 7.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 7.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 7.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic Disease and Others)
    • 7.2.5. By Method (Chemical, Cell-culturing)
    • 7.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 7.2.7. By Country
  • 7.3. Europe: Country Analysis
    • 7.3.1. France Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.1.1. Market Size & Forecast
        • 7.3.1.1.1. By Value
      • 7.3.1.2. Market Share & Forecast
        • 7.3.1.2.1. By Compounds
        • 7.3.1.2.2. By Application
        • 7.3.1.2.3. By Substances
        • 7.3.1.2.4. By Indication
        • 7.3.1.2.5. By Method
        • 7.3.1.2.6. By End-User
    • 7.3.2. Germany Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.2.1. Market Size & Forecast
        • 7.3.2.1.1. By Value
      • 7.3.2.2. Market Share & Forecast
        • 7.3.2.2.1. By Compounds
        • 7.3.2.2.2. By Application
        • 7.3.2.2.3. By Substances
        • 7.3.2.2.4. By Indication
        • 7.3.2.2.5. By Method
        • 7.3.2.2.6. By End-User
    • 7.3.3. United Kingdom Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.3.1. Market Size & Forecast
        • 7.3.3.1.1. By Value
      • 7.3.3.2. Market Share & Forecast
        • 7.3.3.2.1. By Compounds
        • 7.3.3.2.2. By Application
        • 7.3.3.2.3. By Substances
        • 7.3.3.2.4. By Indication
        • 7.3.3.2.5. By Method
        • 7.3.3.2.6. By End-User
    • 7.3.4. Italy Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.4.1. Market Size & Forecast
        • 7.3.4.1.1. By Value
      • 7.3.4.2. Market Share & Forecast
        • 7.3.4.2.1. By Compounds
        • 7.3.4.2.2. By Application
        • 7.3.4.2.3. By Substances
        • 7.3.4.2.4. By Indication
        • 7.3.4.2.5. By Method
        • 7.3.4.2.6. By End-User
    • 7.3.5. Spain Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.5.1. Market Size & Forecast
        • 7.3.5.1.1. By Value
      • 7.3.5.2. Market Share & Forecast
        • 7.3.5.2.1. By Compounds
        • 7.3.5.2.2. By Application
        • 7.3.5.2.3. By Substances
        • 7.3.5.2.4. By Indication
        • 7.3.5.2.5. By Method
        • 7.3.5.2.6. By End-User

8. North America Stable Isotopes Labeled Compounds Market Outlook

  • 8.1. Market Size & Forecast
    • 8.1.1. By Value
  • 8.2. Market Share & Forecast
    • 8.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 8.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 8.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 8.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 8.2.5. By Method (Chemical, Cell-culturing)
    • 8.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 8.2.7. By Country
  • 8.3. North America: Country Analysis
    • 8.3.1. United States Stable Isotopes Labeled Compounds Market Outlook
      • 8.3.1.1. Market Size & Forecast
        • 8.3.1.1.1. By Value
      • 8.3.1.2. Market Share & Forecast
        • 8.3.1.2.1. By Compounds
        • 8.3.1.2.2. By Application
        • 8.3.1.2.3. By Substances
        • 8.3.1.2.4. By Indication
        • 8.3.1.2.5. By Method
        • 8.3.1.2.6. By End-User
    • 8.3.2. Mexico Stable Isotopes Labeled Compounds Market Outlook
      • 8.3.2.1. Market Size & Forecast
        • 8.3.2.1.1. By Value
      • 8.3.2.2. Market Share & Forecast
        • 8.3.2.2.1. By Compounds
        • 8.3.2.2.2. By Application
        • 8.3.2.2.3. By Substances
        • 8.3.2.2.4. By Indication
        • 8.3.2.2.5. By Method
        • 8.3.2.2.6. By End-User
    • 8.3.3. Canada Stable Isotopes Labeled Compounds Market Outlook
      • 8.3.3.1. Market Size & Forecast
        • 8.3.3.1.1. By Value
      • 8.3.3.2. Market Share & Forecast
        • 8.3.3.2.1. By Compounds
        • 8.3.3.2.2. By Application
        • 8.3.3.2.3. By Substances
        • 8.3.3.2.4. By Indication
        • 8.3.3.2.5. By Method
        • 8.3.3.2.6. By End-User

9. South America Stable Isotopes Labeled Compounds Market Outlook

  • 9.1. Market Size & Forecast
    • 9.1.1. By Value
  • 9.2. Market Share & Forecast
    • 9.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 9.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 9.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 9.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 9.2.5. By Method (Chemical, Cell-culturing)
    • 9.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 9.2.7. By Country
  • 9.3. South America: Country Analysis
    • 9.3.1. Brazil Stable Isotopes Labeled Compounds Market Outlook
      • 9.3.1.1. Market Size & Forecast
        • 9.3.1.1.1. By Value
      • 9.3.1.2. Market Share & Forecast
        • 9.3.1.2.1. By Compounds
        • 9.3.1.2.2. By Application
        • 9.3.1.2.3. By Substances
        • 9.3.1.2.4. By Indication
        • 9.3.1.2.5. By Method
        • 9.3.1.2.6. By End-User
    • 9.3.2. Argentina Stable Isotopes Labeled Compounds Market Outlook
      • 9.3.2.1. Market Size & Forecast
        • 9.3.2.1.1. By Value
      • 9.3.2.2. Market Share & Forecast
        • 9.3.2.2.1. By Compounds
        • 9.3.2.2.2. By Application
        • 9.3.2.2.3. By Substances
        • 9.3.2.2.4. By Indication
        • 9.3.2.2.5. By Method
        • 9.3.2.2.6. By End-User
    • 9.3.3. Colombia Stable Isotopes Labeled Compounds Market Outlook
      • 9.3.3.1. Market Size & Forecast
        • 9.3.3.1.1. By Value
      • 9.3.3.2. Market Share & Forecast
        • 9.3.3.2.1. By Compounds
        • 9.3.3.2.2. By Application
        • 9.3.3.2.3. By Substances
        • 9.3.3.2.4. By Indication
        • 9.3.3.2.5. By Method
        • 9.3.3.2.6. By End-User

10. Middle East and Africa Stable Isotopes Labeled Compounds Market Outlook

  • 10.1. Market Size & Forecast
    • 10.1.1. By Value
  • 10.2. Market Share & Forecast
    • 10.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 10.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 10.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 10.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 10.2.5. By Method (Chemical, Cell-culturing)
    • 10.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 10.2.7. By Country
  • 10.3. MEA: Country Analysis
    • 10.3.1. South Africa Stable Isotopes Labeled Compounds Market Outlook
      • 10.3.1.1. Market Size & Forecast
        • 10.3.1.1.1. By Value
      • 10.3.1.2. Market Share & Forecast
        • 10.3.1.2.1. By Compounds
        • 10.3.1.2.2. By Application
        • 10.3.1.2.3. By Substances
        • 10.3.1.2.4. By Indication
        • 10.3.1.2.5. By Method
        • 10.3.1.2.6. By End-User
    • 10.3.2. Saudi Arabia Stable Isotopes Labeled Compounds Market Outlook
      • 10.3.2.1. Market Size & Forecast
        • 10.3.2.1.1. By Value
      • 10.3.2.2. Market Share & Forecast
        • 10.3.2.2.1. By Compounds
        • 10.3.2.2.2. By Application
        • 10.3.2.2.3. By Substances
        • 10.3.2.2.4. By Indication
        • 10.3.2.2.5. By Method
        • 10.3.2.2.6. By End-User
    • 10.3.3. UAE Stable Isotopes Labeled Compounds Market Outlook
      • 10.3.3.1. Market Size & Forecast
        • 10.3.3.1.1. By Value
      • 10.3.3.2. Market Share & Forecast
        • 10.3.3.2.1. By Compounds
        • 10.3.3.2.2. By Application
        • 10.3.3.2.3. By Substances
        • 10.3.3.2.4. By Indication
        • 10.3.3.2.5. By Method
        • 10.3.3.2.6. By End-User

11. Market Dynamics

  • 11.1. Drivers
  • 11.2. Challenges

12. Market Trends & Developments

  • 12.1. Mergers & Acquisitions
  • 12.2. Product Launches
  • 12.3. Technological Advancements

13. Competitive Landscape

  • 13.1. Business Overview
  • 13.2. Company Snapshot
  • 13.3. Products & Services
  • 13.4. Financials (As Reported)
  • 13.5. Recent Developments
  • 13.6. SWOT Analysis
    • 13.6.1. PerkinElmer Inc.
    • 13.6.2. Merck KGaA
    • 13.6.3. 3M Company
    • 13.6.4. Cambridge Isotope Laboratories, Inc.
    • 13.6.5. JSC Isotope
    • 13.6.6. Creative Proteomics
    • 13.6.7. Medical Isotopes, Inc.
    • 13.6.8. Omicron Biochemicals, Inc.
    • 13.6.9. Trace Sciences International
    • 13.6.10. Nippon Sanso Holdings Corporation

14. Strategic Recommendations