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市場調查報告書
商品編碼
1828103
2025年全球克隆與誘變市場報告Cloning And Mutagenesis Global Market Report 2025 |
近年來,克隆和誘變市場規模迅速擴張,從2024年的29.8億美元成長到2025年的35.4億美元,複合年成長率為18.7%。預測期內的成長可歸因於基因研究的進步、藥物研究需求的不斷成長、農業領域基因工程的興起、生物醫學研究應用以及分子生物學領域的開創性應用。
預計未來幾年克隆與誘變市場將快速成長,到2029年將達到71.3億美元,年複合成長率(CAGR)為19.2%。預測期內的成長可歸因於基因治療應用的不斷擴展、個性化醫療需求的不斷成長、功能基因組學的進步、合成生物學的創新以及農業生物技術的應用。預測期內的主要趨勢包括治療中的標靶基因編輯、更高的精準度和特異性、可自訂的分子工具、農業應用的不斷擴展以及倫理和監管考慮。
克隆和誘變是分子生物學中的重要技術,涉及複製多個相同的DNA片段、基因或整個基因組,以及在DNA序列中引入突變。這些技術在研究基因功能和調控、開發新藥和新療法以及生產重組酶和蛋白質方面發揮著重要作用。
與克隆和誘變相關的關鍵產品包括克隆試劑套件、誘變試劑套件和其他相關工具。克隆試劑套件是專門設計的實驗室儀器,旨在簡化將特定DNA片段或基因克隆到克隆載體的過程。這些套件對於各種克隆實驗至關重要,包括基因克隆、亞克隆、特異性突變和文庫構建。平端克隆、拓樸PCR克隆、無縫克隆和特異性誘變等技術被學術和研究機構、生物技術公司以及其他營業單位分子生物學研究的實體所採用。
2025年春季美國關稅的突然上調及其引發的貿易摩擦對醫療設備行業產生了重大影響,尤其對用於診斷影像設備的進口零件、手術用不銹鋼和一次性塑膠製品產生了重大影響。由於醫院和診所抵制漲價,製造商面臨利潤壓力。監管挑戰使情況更加複雜,因為由於關稅而更換供應商通常需要重新認證醫療設備,導致市場進入延遲。為此,企業正在透過雙重採購關鍵零件、增加標準化產品的國內生產以及加快尋找更具成本效益的材料來降低風險。
本研究報告是商業研究公司 (The Business Research Company) 最新報告系列的一部分,該系列提供了克隆和誘變軟體市場統計數據,包括全球市場規模、各地區市場佔有率、競爭對手的克隆和誘變軟體市場佔有率、詳細的克隆和誘變軟體細分市場、市場趨勢和商業機會,以及您在克隆和誘變軟體行業取得成功所需的數據。本克隆和誘變軟體市場研究報告對該行業的現狀和未來趨勢進行了詳細分析,為您提供所需的一切資訊的完整觀點。
我們預測未來五年該市場將成長19.2%,較先前預測略有下降0.1%。這一下降主要源自於美國與其他國家之間關稅的影響。這種影響可能會透過對來自芬蘭和比利時等關鍵地區的限制性酵素和特異性誘變試劑套件徵收關稅直接影響美國,從而減緩生物技術研究的進展並增加分子生物學實驗的成本。由於互惠關稅以及貿易緊張局勢和限制措施加劇對全球經濟和貿易的負面影響,這種影響也將更加廣泛。
受基因改造產品需求成長的推動,克隆和誘變市場預計將成長。基因改造產品包括經過精心設計的基因操作以引入新性狀或特性的生物、材料和物質。克隆是一種創建精確基因拷貝的科學過程,具有多種應用,包括培育抗性昆蟲和植物品種,以及促進醫學中的基因治療。根據德國生物技術和製藥公司拜耳股份公司的年度報告,基因改造產品的銷售額正在大幅成長,作物科學部門的銷售額將從 2021 年的 223.1479 億美元增至 2022 年的 277.9438 億美元。對基因改造產品日益成長的需求是克隆和誘變市場的主要驅動力。這些數據是根據拜耳股份公司 2023 年 2 月發布的年度報告中提供的資訊。
由於對個人化醫療的需求不斷成長,克隆和誘變市場預計將成長。個人化醫療是一種創新的醫療保健方法,可根據每位患者的個人特徵量身訂做治療和介入措施。克隆和誘變在個人化醫療的各個方面發揮關鍵作用,包括疾病建模、藥物開發、標靶識別、基因治療、生物標記發現、患者特異性細胞治療、藥物基因組學和個人化治療的基因組編輯。 2022 年 4 月,個人化醫療聯盟報告稱,美國食品藥物管理局(FDA) 藥品評估和研究中心 (CDER) 在 2022 年核准了37 個新分子實體 (NME)。在治療性 NME 中,約 34%(其中 12 個)被個人化醫療聯盟 (PMC) 歸類為個人化醫療。對個人化醫療的這種不斷成長的需求是推動克隆和誘變市場成長的主要因素。
克隆和誘變市場的主要企業正在利用噬菌體基因組改造技術等先進技術來提升其競爭地位。噬菌體基因組改造技術旨在有意改變噬菌體(一種感染細菌的病毒)的遺傳物質,用於研究、治療和工業應用。例如,韓國生物技術公司 iNtRON BIoTechnology 於 2022 年 10 月推出了其第二代機器人噬菌體技術。此技術利用隨機轉座子誘變技術來改造噬菌體的基因組,從而識別和去除非必需基因。 iNtRON 旨在設計和生產具有特定特性的噬菌體,以促進免疫療法和抗病毒解決方案的開發。
為了保持競爭力,克隆和誘變市場的主要企業也積極探索聚合酵素鏈鎖反應(PCR) 等創新技術。 PCR 是一種擴增特定 DNA 片段的分子生物學實驗室技術。美國生技公司 Bio-Rad Laboratories 於 2023 年 4 月推出了 ID-Check 物種形成解決方案。這種即時PCR方法有助於肉類物種識別,能夠識別食品、飼料和環境樣本中的動物類型。它提供了一種可靠、快速的原料來源驗證方法,並增強了生產線清潔流程。此解決方案以高靈敏度檢測各種肉類物種的粒線體 DNA,可檢測濃度低至 0.001% 的 DNA。它採用雙重檢測系統,確保準確性和便利性。
2022年5月,QIAGEN NV(荷蘭)收購了BLIRT SA。此次收購旨在增強QIAGEN在創新分子診斷和生物製藥解決方案開發方面的能力。 BLIRT是一家總部位於波蘭的製造商,專門生產用於分子克隆和定點特異性的重組酶。
克隆與誘變市場的主要企業包括賽默飛世爾科技、Takara Bio Inc.、安捷倫科技公司、Jena Bioscience GmbH、Transgen Biotech Co、New England Biolabs、默克公司、Promega Corporation、Bio-Rad Laboratories Inc.、丹納赫、Genomax Technologies Pte Ltd、GENEWIZx、abmak Inc. Sciences、Bio-Techne、Charles River Laboratories、Integrated DNA Technologies、MedGenome、Sino Biological Inc.、BioChain Institute Inc.、OriGene Technologies Inc.、Creative Biogene、Bioneer Corporation、Synbio Technologies LLC、Lucigen Corporation、Biomatik Corporation、Quanta BioDesign Ltd. 和 Inscripta Inc.。
2024年克隆和誘變市場最大的地區是北美。預計在預測期內,亞太地區將成為全球克隆和誘變市場報告中所預測成長最快的地區。克隆和誘變市場報告涵蓋亞太地區、西歐、東歐、北美、南美以及中東和非洲。
克隆和誘變市場報告涵蓋的國家:澳洲、巴西、中國、法國、德國、印度、印尼、日本、俄羅斯、韓國、英國、美國、加拿大、義大利、西班牙
克隆和誘變市場包括營業單位透過檢測試劑套件、生物素-PEG連接體、比勒蛋白和細胞產生的收益。市場規模包括服務供應商銷售或包含在其服務產品中的相關產品的價值。克隆和誘變市場也包括DNA分離、克隆載體和DNA連接酶等技術的銷售。此市場的價值是指「工廠門口」價值,即產品製造商或創造者向其他營業單位(包括下游製造商、批發商、經銷商和零售商)或直接向最終客戶銷售的產品價值。該市場中的產品價值還包括產品創造者銷售的任何相關服務。
Cloning and mutagenesis are integral techniques within molecular biology that involve the replication of multiple identical copies of a DNA fragment, gene, or entire genome, along with the introduction of mutations into a DNA sequence. These techniques play a crucial role in studying gene function and regulation, facilitating the development of new drugs and therapeutics, and producing recombinant enzymes and proteins.
The primary products associated with cloning and mutagenesis include cloning kits, mutagenesis kits, and other related tools. Cloning kits are specialized laboratory instruments designed to streamline the process of cloning specific DNA fragments or genes into a cloning vector. These kits are essential for various cloning experiments, including gene cloning, subcloning, site-directed mutagenesis, and library construction. Techniques such as blunt end cloning, topo PCR cloning, seamless cloning, site-directed mutagenesis, among others, are employed by academic and research institutions, biotechnology companies, and other entities engaged in molecular biology research.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sharp increase in U.S. tariffs and resulting trade tensions in spring 2025 are significantly impacting the medical equipment sector, especially for imported components used in imaging machines, surgical-grade stainless steel, and disposable plastics. With hospitals and clinics pushing back against price increases, manufacturers are facing margin pressure. The situation is further complicated by regulatory challenges, as switching suppliers due to tariffs often necessitates re-certification of medical devices, leading to delays in market entry. In response, companies are mitigating risks by dual-sourcing key components, ramping up domestic production of standardized items, and accelerating research into more cost-effective materials.
The cloning and mutagenesis software market research report is one of a series of new reports from The Business Research Company that provides cloning and mutagenesis software market statistics, including cloning and mutagenesis software industry global market size, regional shares, competitors with a cloning and mutagenesis software market share, detailed cloning and mutagenesis software market segments, market trends and opportunities, and any further data you may need to thrive in the cloning and mutagenesis software industry. This cloning and mutagenesis software market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The cloning and mutagenesis market size has grown rapidly in recent years. It will grow from $2.98 billion in 2024 to $3.54 billion in 2025 at a compound annual growth rate (CAGR) of 18.7%. The growth in the historic period can be attributed to advancements in genetic research, increasing demand in pharmaceutical research, rise of genetic engineering in agriculture, biomedical research applications, pioneer applications in molecular biology.
The cloning and mutagenesis market size is expected to see rapid growth in the next few years. It will grow to $7.13 billion in 2029 at a compound annual growth rate (CAGR) of 19.2%. The growth in the forecast period can be attributed to expanding applications in gene therapy, rising demand for personalized medicine, advancements in functional genomics, innovations in synthetic biology, application in agricultural biotechnology. Major trends in the forecast period include targeted gene editing in therapeutics, enhanced precision and specificity, customizable molecular tools, expanded applications in agriculture, ethical and regulatory considerations.
The forecast of 19.2% growth over the next five years indicates a slight reduction of 0.1% from the previous estimate for this market.This reduction is primarily due to the impact of tariffs between the US and other countries. This is likely to directly affect the US through tariffs on restriction enzymes and site-directed mutagenesis kits, sourced from key regions such as Finland and Belgium, which could lead to slowed biotech research progress and higher molecular biology experiment costs.The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.
The cloning and mutagenesis market is expected to experience growth driven by the rising demand for genetically modified products. Genetically modified products involve organisms, materials, or substances that undergo deliberate genetic engineering to introduce new traits or characteristics. Cloning, a scientific process for producing exact genetic copies, is utilized in various applications, including creating insect and plant-resistant species and facilitating gene therapy in medical sciences. An annual report from Bayar AG, a Germany-based biotechnology and pharmaceutical company, revealed significant growth in the sales of genetically modified products, with the crop sciences segment reaching $27,794.38 million in 2022, up from $22,314.79 million in 2021. This increased demand for genetically modified products is a key driver of the cloning and mutagenesis market. The data is based on information provided in the annual report published by Bayar AG in February 2023.
The cloning and mutagenesis market is anticipated to grow due to the increasing demand for personalized medicine. Personalized medicine is an innovative healthcare approach that tailors medical treatment and interventions to the unique characteristics of each patient. Cloning and mutagenesis play crucial roles in various aspects of personalized medicine, such as disease modeling, drug development, target identification, gene therapy, biomarker discovery, patient-specific cell therapies, pharmacogenomics, and genome editing for personalized therapies. In April 2022, the Personalized Medicine Coalition reported that the Food and Drug Administration's Center for Drug Evaluation and Research (CDER) approved 37 new molecular entities (NMEs) in 2022. Among the therapeutic NMEs, approximately 34% (12 of them) were classified as personalized medicines by the Personalized Medicine Coalition (PMC). This increasing demand for personalized medicine is a significant driver of the growth in the cloning and mutagenesis market.
Major players in the cloning and mutagenesis market are leveraging advanced technologies, such as bacteriophage genome modifying technologies, to enhance their competitive position. Bacteriophage genome modifying technologies involve intentional alterations to the genetic material of bacteriophages, viruses that infect bacteria, for applications in research, therapy, or industry. An example is iNtRON Biotechnology, a South Korea-based biotech company, which introduced its 2nd generation Robot Bacteriophage technology in October 2022. This technology utilizes random transposon mutagenesis to modify the bacteriophage genome, enabling the identification and removal of non-essential genes. iNtRON aims to design and produce bacteriophages with specific characteristics, facilitating the development of immunotherapeutic agents and antiviral solutions.
Leading companies in the cloning and mutagenesis markets are also actively exploring innovative techniques such as Polymerase Chain Reaction (PCR) to maintain a competitive edge. PCR is a molecular biology laboratory technique that amplifies specific DNA segments. Bio-Rad Laboratories, Inc., a US-based biotech company, launched the ID-Check Speciation Solution in April 2023. This real-time PCR method aids in meat speciation, allowing the identification of animal species in food, feed, and environmental samples. It provides a reliable and rapid means to verify raw material origins, enhancing production line cleaning processes. The solution targets mitochondrial DNA from various meat species with exceptional sensitivity, detecting DNA concentrations as low as 0.001%. It features a duplex detection system for accuracy and user convenience.
In May 2022, QIAGEN N.V., a Netherlands-based provider of sample and assay technologies, acquired BLIRT SA for an undisclosed amount. This acquisition is intended to bolster QIAGEN's capabilities in developing innovative molecular diagnostics and biopharmaceutical solutions. BLIRT SA, a manufacturer based in Poland, specializes in recombinant enzymes used for molecular cloning and site-directed mutagenesis.
Major companies operating in the cloning and mutagenesis market include Thermo Fisher Scientific, Takara Bio Inc., Agilent Technologies Inc., Jena Bioscience GmbH, Transgen Biotech Co, New England Biolabs, Merck KGaA, Promega Corporation, Bio-Rad Laboratories Inc., Danaher, Genomax Technologies Pte Ltd, GENEWIZ Inc., abm Inc., GenScript, EZBioscience, Codex DNA Inc., Aragen Life Sciences, Bio-Techne, Charles River Laboratories, Integrated DNA Technologies, MedGenome, Sino Biological Inc., BioChain Institute Inc., OriGene Technologies Inc., Creative Biogene, Bioneer Corporation, Synbio Technologies LLC, Lucigen Corporation, Biomatik Corporation, Quanta BioDesign Ltd., Inscripta Inc.
North America was the largest region in the cloning and mutagenesis market in 2024. Asia-pacific is expected to be the fastest-growing region in the global cloning and mutagenesis market report during the forecast period. The regions covered in the cloning and mutagenesis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
The countries covered in the cloning and mutagenesis market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain
The cloning and mutagenesis market includes revenues earned by entities by assay kits, biotin-peg linkers, Bira proteins, and cells. The market value includes the value of related goods sold by the service provider or included within the service offering. The cloning and mutagenesis market also includes of sales of techniques such as the isolation of DNA, cloning vectors, and DNA ligase. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Cloning And Mutagenesis Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on cloning and mutagenesis market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for cloning and mutagenesis ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The cloning and mutagenesis market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.