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市場調查報告書
商品編碼
2041729
皮膚毒性測試市場預測至2034年—按類型、測試方法、測試類別、最終用戶和地區分類的全球分析Dermal Toxicity Testing Market Forecasts to 2034 - Global Analysis By Type (Product, Services and Other Types), Testing Method (In-vitro Testing, In-silico Modeling and In-vivo testing), Test Type, End User and By Geography |
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根據 Stratistics MRC 的數據,預計到 2026 年,全球皮膚毒性測試市場規模將達到 30 億美元,並在預測期內以 10.3% 的複合年成長率成長,到 2034 年將達到 67 億美元。
經皮毒性試驗是一種科學方法,用於評估化學物質與皮膚接觸後可能產生的不良反應。這種試驗對於評估各種產品(包括化妝品、藥品和工業化學品)的安全性至關重要。經皮毒性試驗評估的參數包括皮膚外觀、紅斑(發紅)、水腫(腫脹)和其他刺激症狀。
據癌症研究所稱,正在研發的活性成分數量增加了90%以上,2019年達到3876種。目前,正在考慮使用囓齒動物進行長期致癌性研究,以評估藥物對人類的致癌性。
擴大研發活動
研發活動的拓展凸顯了新產品和新配方開發在將創新且安全的產品推向市場方面所發揮的關鍵作用。全面的皮膚毒性測試對於評估這些新產品的安全性至關重要。此外,為了遵守不斷變化的監管標準、保護公眾健康並建立消費者對新產品安全性的信心,對皮膚毒性測試服務的需求也不斷成長。
高成本
皮膚毒性測試需要專門的設施和設備,以確保結果的準確性和可靠性。維護這些設施、安裝和維護測試設備以及聘用熟練人員的成本可能相當高昂。需要測試的物質的複雜性和多樣性也會增加這些成本。此外,監管要求的變化可能需要進行額外的測試並更新調查方法,導致合規成本增加並阻礙市場擴張。
消費者意識不斷增強
隨著消費者對皮膚健康和安全的意識不斷增強,他們開始仔細查看產品標籤,並要求製造商提高透明度。消費者越來越意識到接觸個人保健產品、化妝品和藥品中某些化學物質可能帶來的風險。此外,這種對安全的重視也符合消費者對健康和環境永續性產品的更廣泛需求,從而推動了市場成長。
缺乏標準化
由於缺乏標準化的規程和指南,準確進行風險評估和解讀不同實驗室及研究的測試結果變得困難。此外,建立用於判定與經皮接觸相關的物質安全性的統一標準也面臨挑戰。更重要的是,這種缺乏協調導致監管機構和相關人員的效率低下和成本增加,阻礙了市場擴張。
新冠疫情的感染疾病
新冠疫情對經皮毒性測試市場造成了多方面的負面影響。該市場嚴重依賴製藥、化妝品和化學工業,而這些行業在經皮期間都受到衝擊。實驗室關閉、設施准入受限以及員工流動受限阻礙了經皮毒性測試的順利開展,進而影響了產品核准和上市計劃。此外,景氣衰退也導致一些公司重新評估其在非必要測試服務方面的投資,從而影響了整體市場成長。
在預測期內,In Silico模擬領域預計將佔據最大佔有率。
In Silico模擬領域預計將佔據最大的市場佔有率,因為它旨在透過模擬分子間相互作用、吸收速率以及對皮膚的潛在不良反應,來準確預測皮膚毒性。這些模型有助於減少動物試驗,符合倫理考量和監管要求,從而最大限度地減少試驗程序中動物的使用。此外,機器學習和人工智慧等技術的進步提高了In Silico模型的準確性和可靠性,使其成為毒性評估中不可或缺的工具,並推動了該領域的成長。
預計在預測期內,皮膚腐蝕測試領域將呈現最高的複合年成長率。
預計在預測期內,皮膚腐蝕測試領域將呈現最高的複合年成長率。皮膚腐蝕是指嚴重的皮膚損傷,其特徵是皮膚組織破壞和化學燒燙傷。這些測試通常包括將測試物質塗抹在實驗動物或體外模型的皮膚上,並觀察皮膚損傷的程度。此外,測試結果有助於將物質分類為腐蝕性或非腐蝕性,為產品安全評估提供重要數據,並指南監管決策和安全評估。這正在推動該領域的成長。
在預測期內,亞太地區佔據了最大的市場佔有率,這主要得益於工業成長、監管環境改善以及消費者產品安全意識不斷提高等動態因素。該地區涵蓋中國、日本、印度和韓國等多元化經濟體,這些經濟體透過完善的毒性測試方案,為確保產品安全做出了貢獻。此外,消費者對個人保健產品和藥品的日益關注,也進一步推動了該地區對全面皮膚毒性測試的需求。
預計在預測期內,歐洲將錄得最高的複合年成長率,這主要得益於對消費者安全的高度重視以及對尖端調查方法(尤其是體外和電腦模型等替代方法)的顯著應用。查爾斯河實驗室國際公司、Mattec公司、Intertek集團和GE醫療等領導企業正致力於提高經皮毒性評估的準確性和效率。此外,美國環保署(EPA)和食品藥物管理局(FDA)等機構制定的嚴格監管標準凸顯了全面毒性測試的重要性,這也推動了該地區市場的發展。
According to Stratistics MRC, the Global Dermal Toxicity Testing Market is accounted for $3.0 billion in 2026 and is expected to reach $6.7 billion by 2034 growing at a CAGR of 10.3% during the forecast period. Dermal toxicity testing is a scientific method employed to assess the potential harmful effects of chemical substances when they come into contact with the skin. This type of testing is crucial for evaluating the safety of various products, including cosmetics, pharmaceuticals, and industrial chemicals. Various parameters are assessed during dermal toxicity testing, such as skin appearance, erythema (redness), edema (swelling), and other signs of irritation.
According to the Cancer Research Institute, the number of active drugs in development grew by more than 90%, to 3,876 in 2019. Long-term rodent carcinogenicity studies for assessing the carcinogenic potential of drugs in humans are currently being examined.
Increasing research and development activities
The growth in R&D activities underscores the pivotal role of the development of new products and formulations to introduce innovative and safe products to the market. Comprehensive dermal toxicity testing becomes imperative to assess the safety profile of these advancements. Further, by the need to align with evolving regulatory standards, safeguard public health, and instill consumer confidence in the safety of newly developed products, the demand for dermal toxicity testing services is propelled.
High cost
Dermal toxicity testing requires specialized facilities and equipment to ensure accurate and reliable results. The costs of maintaining such facilities, acquiring and maintaining testing equipment, and employing skilled personnel can be significant. The complexity and diversity of substances that require testing further contribute to the costs. Furthermore, as regulatory requirements evolve, additional tests or updated methodologies may be necessary, leading to increased costs for compliance, which is hampering this market expansion.
Rising consumer awareness
Rising awareness regarding skin health and safety prompts consumers to scrutinize product labels and demand transparency from manufacturers. Consumers are becoming more conscious of the potential risks associated with exposure to certain chemicals present in personal care products, cosmetics, and pharmaceuticals. Additionally, this emphasis on safety aligns with the broader trend of consumers seeking products that prioritize health and environmental sustainability, which are driving this market size.
Limited standardization
The absence of standardized protocols and guidelines made it challenging to make accurate risk assessments and interpret test results obtained from different laboratories or studies. It also made it difficult to establish consistent criteria for determining the safety of substances in relation to dermal exposure. Moreover, the lack of harmonization resulted in inefficiencies and increased costs for both regulators and industry stakeholders, which are hindering this market expansion.
Covid-19 Impact
The COVID-19 pandemic has had several negative impacts on the dermal toxicity testing market. The dermal toxicity testing market relies heavily on the pharmaceutical, cosmetic, and chemical sectors, all of which experienced disruptions during the pandemic. Laboratory closures, restricted access to facilities, and limitations on workforce mobility impeded the smooth conduct of dermal toxicity tests, affecting timelines for product approvals and introductions. Furthermore, the economic downturn has prompted some businesses to reconsider their investments in non-essential testing services, affecting overall market growth.
The in-silico modeling segment is expected to be the largest during the forecast period
The in-silico modeling segment is estimated to hold the largest share, due to they aim to provide accurate predictions of dermal toxicity by simulating molecular interactions, absorption rates, and potential adverse effects on the skin. These models contribute to the reduction of animal testing, aligning with ethical considerations and regulatory efforts to minimize animal use in testing procedures. In addition, advancements in technology, such as machine learning and artificial intelligence, enhance the accuracy and reliability of in-silico models, making them valuable tools in toxicology assessments which are driving this segment's growth.
The skin corrosion tests segment is expected to have the highest CAGR during the forecast period
The skin corrosion tests segment is anticipated to have highest CAGR during the forecast period. It refers to severe damage to the skin, often characterized by the destruction of skin tissue, leading to chemical burns. These tests typically involve the application of the test substance to the skin of experimental animals or in vitro models, and observations are made to determine the extent of skin damage. Furthermore, the results help classify substances as corrosive or non-corrosive, guiding regulatory decisions and safety assessments by providing essential data for product safety assessments, which is boosting this segment expansion.
Asia Pacific commanded the largest market share during the extrapolated period owing to a dynamic landscape influenced by factors such as industrial growth, regulatory developments, and increasing awareness of product safety. The region encompasses diverse economies, including China, Japan, India, South Korea, and others, contributing to ensuring the safety of products through robust toxicity testing protocols. Moreover, increased awareness among consumers regarding personal care and pharmaceutical products further propels the demand for comprehensive dermal toxicity testing in this region.
Europe is expected to witness highest CAGR over the projection period, owing to a strong focus on consumer safety and cutting-edge testing methodologies, with a notable shift towards alternative methods such as in vitro and in silico models. Key players such as Charles River Laboratories International, MatTek Corporation, Intertek Group, and GE Healthcare contribute to the accuracy and efficiency of dermal toxicity assessments. Further, stringent regulatory standards set by agencies like the U.S. Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) emphasize the importance of comprehensive toxicity testing, thereby driving this region.
Key players in the market
Some of the key players in the Dermal Toxicity Testing Market include SGS S.A, Bio-Rad Laboratories Inc., Charles River Laboratories International, Inc., Catalent, Inc., Eurofins Scientific Inc, Thermo Fisher Scientific, Inc., Covance, Inc , GE Healthcare, Qiagen N.V., Merck KgaA, Intertek Group, MatTek Corporation and Evotec.
In December 2023, GE HealthCare and Nantworks AirStrip announced an agreement to Commercialize Integrated Patient Monitoring and Cardiac Data Visualization for Healthcare Systems.
In December 2023, SGS is pleased to announce the signing of an agreement to divest its crop science operations in 14 countries to Eurofins Scientific.
In November 2023, GE HealthCare (Nasdaq: GEHC) and Masimo announced a joint agreement to integrate Masimo Signal Extraction Technology (SET) pulse oximetry into GE HealthCare's Portrait Mobile wireless and wearable patient monitoring solution.
In October 2023, SGS is pleased to have signed an agreement to divest its US powertrain testing operations as part of its strategic portfolio evolution to Columbia River Partners, a private equity firm focused on the industrials, business services and IT services sectors.