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市場調查報告書
商品編碼
2041657
紅血球生成素製劑市場預測至2034年-按類型、產品類別、通路、應用、最終用戶和地區分類的全球分析Erythropoietin Drugs Market Forecasts to 2034 - Global Analysis By Type (Biosimilars and Biologics), Product (Epoetin-alfa, Epoetin-beta, Darbepoetin-alfa and Other Products), Distribution Channel, Application, End User and By Geography |
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根據 Stratistics MRC 預測,全球促紅血球生成素市場預計到 2026 年將達到 155 億美元,並在預測期內以 13.2% 的複合年成長率成長,到 2034 年達到 418 億美元。
促紅血球生成素製劑是一類含有重組促紅血球生成素的藥物,促紅血球生成素是一種由腎臟自然產生的荷爾蒙。這些藥物旨在刺激和增加紅血球合成,有效緩解貧血相關症狀。透過增加紅血球數,促紅血球生成素製劑可以治療貧血症狀,例如虛弱、呼吸困難和頭暈,從而改善患者的日常生活功能。
根據世界衛生組織(WHO)的數據,全球 42% 的五歲以下兒童和 40% 的孕婦患有貧血。
貧血盛行率增加
貧血是一種以紅血球數量減少或血紅素水平降低為特徵的疾病,導致血液攜氧能力下降。促紅血球生成素(EPO)製劑透過刺激紅血球生成在貧血治療中發揮至關重要的作用。此外,EPO製劑也常用於治療化療引起的貧血,並改善癌症患者的生活品質。這些疾病盛行率的不斷上升加重了貧血對整體人群的負擔,從而推高了對EPO製劑的需求。
潛在副作用
促紅血球生成素市場面臨與治療用途相關的副作用的潛在限制因素。其中一個主要擔憂是促紅血球生成素給藥可能引發血栓症和高血壓等心血管事件的風險。另一個潛在的副作用是純紅血球生成相關性紅血球生成症(PRCA)的發生,這是一種罕見但嚴重的疾病,其特徵是紅血球生成突然停止。
人們對醫療保健的認知不斷提高
醫療保健意識的不斷提高是紅血球生成素市場的主要驅動力。隨著患者和醫療專業人員對包括貧血在內的各種健康狀況的認知不斷增強,紅血球生成素在治療貧血相關併發症的重要性也日益凸顯。此外,患者越來越希望獲得針對慢性腎臟病和其他需要紅血球生成素發揮關鍵作用的疾病的及時有效的治療方法。這些因素共同推動了市場需求。
新型替代療法的興起
隨著科學和醫學研究的進步,包括非藥物療法和替代療法在內的新治療方案日益受到關注,對促紅血球生成素製劑的市場主導地位構成了挑戰。此外,生物相似藥在市場上的普及和應用日益廣泛,可能導致價格壓力和市場競爭加劇,進而影響品牌促紅血球生成素製劑的收入。
新冠疫情的感染疾病
新冠疫情對促紅血球生成素市場造成了顯著衝擊。包括用於治療貧血的促紅血球生成素製劑在內的非緊急醫療程序和治療被推遲或延期,影響了整體市場需求。此外,藥品供應鏈中斷、旅行限制和勞動力短缺也阻礙了促紅血球生成素製劑的生產和分銷。
在預測期內,腫瘤領域預計將佔據最大佔有率。
據估計,癌症患者佔比最大。癌症患者常因疾病本身和化療的副作用而出現貧血。促紅血球生成素製劑,例如重組人類促紅血球生成素(epoetin alfa),透過刺激紅血球生成來治療癌症患者的貧血。此外,促紅血球生成素療法可透過維持足夠的攜氧紅血球水平來改善患者的整體健康狀況,並使癌症治療更加有效。
在預測期內,生物製劑領域預計將呈現最高的複合年成長率。
預計生物製劑部門在預測期內將顯著成長。生物製劑產品旨在模擬促紅血球生成素的天然功能,促紅血球生成素刺激骨髓中紅血球的生成。促紅血球生成素製劑廣泛用於治療慢性腎臟病、癌症化療及其他特定疾病所引起的貧血。此外,包括促紅血球生成素製劑在內的生物製藥產品,透過提供針對性強、療效顯著的貧血治療方案,為患者照護做出了重要貢獻。
由於北美擁有完善的醫療保健基礎設施、技術創新以及較高的疾病盛行率,因此在預測期內佔據了最大的市場佔有率。貧血的盛行率,尤其是在接受透析治療的慢性腎臟病(CKD)患者和接受癌症治療的患者中,推動了北美對促紅血球生成素製劑的需求。此外,該地區在生物技術和藥物研究方面處於領先地位,並持續推動促紅血球生成素製劑的研發創新。
由於亞太地區對全球製藥業的重大貢獻,預計該地區在預測期內將實現盈利成長。中國和印度等國家正在崛起,成為促紅血球生成素製劑生產和消費的主要參與者。該地區的製藥業受益於積極的研發活動,這些活動推動了創新和新型促紅血球生成素製劑的推出。此外,亞太地區醫療基礎設施的完善和醫療支出的成長也促進了促紅血球生成素製劑市場的成長。
According to Stratistics MRC, the Global Erythropoietin Drugs Market is accounted for $15.5 billion in 2026 and is expected to reach $41.8 billion by 2034 growing at a CAGR of 13.2% during the forecast period. Erythropoietin drugs are a class of medications that include recombinant forms of erythropoietin, a hormone produced naturally in the kidneys. These drugs are designed to stimulate and increase the synthesis of red blood cells, making them effective in managing conditions associated with anaemia. Erythropoietin medications treat anaemia symptoms such as weakness, dyspnea, and vertigo by raising red blood cell counts, leading to improved daily functioning for patients.
According to the World Health Organization (WHO), 42% of children under the age of five and 40% of pregnant women worldwide are anemic.
Rising prevalence of anaemia
Anaemia is a condition characterized by a decrease in the number of red blood cells or a decrease in the amount of haemoglobin, leading to reduced oxygen-carrying capacity in the blood. EPO drugs play a crucial role in managing anaemia by stimulating the production of red blood cells. Moreover, EPO drugs are often prescribed to cancer patients to manage chemotherapy-induced anaemia and improve their quality of life. The increasing prevalence of these conditions contributes to the overall burden of anaemia in the population, thereby driving the demand for EPO drugs.
Potential adverse effects
The erythropoietin drug market faces potential restraints linked to the occurrence of adverse effects associated with the therapeutic use of these drugs. One significant concern is the risk of cardiovascular events, including thrombosis and hypertension, associated with the administration of erythropoietin drugs. Furthermore, another potential adverse effect is the development of pure red cell aplasia (PRCA), a rare but serious condition characterized by a sudden halt in the production of red blood cells.
Increased healthcare awareness
Increased healthcare awareness serves as a pivotal driver in the erythropoietin drugs market. As awareness about health conditions, including anemia, continues to rise among patients and healthcare professionals, there is a heightened recognition of the significance of erythropoietin drugs in managing anemia-associated complications. Moreover, patients are increasingly seeking timely and effective treatments for conditions like chronic kidney disease and other disorders where erythropoietin drugs play a vital role. These factors drive market demand.
Emerging alternatives
As scientific and medical research progresses, new therapeutic options, including non-pharmacological interventions and alternative drug therapies, are gaining attention and posing a challenge to the dominance of erythropoietin drugs. Moreover, the increasing availability and adoption of biosimilars in the market can lead to pricing pressures and market share competition, impacting the revenue of branded erythropoietin drugs.
Covid-19 Impact
The erythropoietin drug market experienced notable impacts from the COVID-19 pandemic. Non-urgent medical procedures and treatments, including those involving erythropoietin drugs for anaemia, were deferred or delayed, affecting the overall market demand. Additionally, disruptions in the pharmaceutical supply chain, restrictions on movement, and workforce shortages posed obstacles to the production and distribution of erythropoietin drugs.
The cancer segment is expected to be the largest during the forecast period
The cancer segment is estimated to hold the largest share. Cancer patients frequently experience anaemia due to the effects of the disease itself or as a side effect of chemotherapy. Erythropoietin drugs, such as epoetin-alfa, are employed to address anaemia in cancer patients by stimulating the production of red blood cells. Moreover, erythropoietin therapies improve the patient's well-being, potentially allowing for more effective cancer treatment by maintaining adequate levels of oxygen-carrying red blood cells.
The biologics segment is expected to have the highest CAGR during the forecast period
The biologics segment is anticipated to have lucrative growth during the forecast period. Biologics are designed to mimic the natural function of erythropoietin in stimulating the production of red blood cells in the bone marrow. Erythropoietin biologics are commonly used to address anaemia associated with chronic kidney disease, cancer chemotherapy, and certain other medical conditions. Additionally, biologics, including erythropoietin-based agents, contribute significantly to patient care by offering targeted and effective treatments for anaemia.
North America commanded the largest market share during the extrapolated period owing to robust healthcare infrastructure, technological innovation, and a high prevalence of conditions. The prevalence of anaemia, particularly in CKD patients undergoing dialysis and individuals undergoing cancer treatments, has fuelled the demand for erythropoietin drugs in North America. Moreover, the region is also at the forefront of biotechnological and pharmaceutical research, driving continuous innovation in erythropoietin drug development.
Asia Pacific is expected to witness profitable growth over the projection period, owing to its significant contribution to the global pharmaceutical industry. Countries like China and India have emerged as key players in the production and consumption of erythropoietin drugs. The region's pharmaceutical sector benefits from robust research and development activities, fostering innovation and the introduction of new EPO formulations. Additionally, the Asia-Pacific's evolving healthcare infrastructure and increasing healthcare expenditure contribute to the growth of the erythropoietin drug market.
Key players in the market
Some of the key players in the Erythropoietin Drugs Market include Johnson & Johnson Services, Inc., AstraZeneca, Amgen, Inc., Novartis AG, Teva Pharmaceutical Industries Ltd., Pfizer Inc, LG Chem, F. Hoffmann-La Roche Ltd., Sun Pharmaceutical Industries Ltd., Intas Pharmaceuticals Ltd., Dr. Reddy's Laboratories Ltd, Ranbaxy Laboratories and Roche Diagnostics.
In November 2023, AstraZeneca announced a collaboration and investment agreement with Cellectis, a clinical-stage biotechnology company, to accelerate the development of next generation therapeutics in areas of high unmet need, including oncology, immunology and rare diseases.
In September 2023, Sun Pharmaceutical Industries Limited announced that it had entered into a licence agreement with American biopharmaceutical company Pharmazz Inc to commercialise an innovative drug, Tyvalzi (Sovateltide) in India.
In January 2022, Amgen and Generate Biomedicines announced a research collaboration agreement to discover and create protein therapeutics for five clinical targets across several therapeutic areas and multiple modalities.
In October 2020, Novartis and Molecular Partners AG announced collaboration in the form of an option and license agreement to develop, manufacture and commercialize Molecular Partners' anti-COVID-19 DARPin(R) program, consisting of two therapeutic candidates, MP0420 and MP0423.