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市場調查報告書
商品編碼
1822388
2032 年登革熱疫苗市場預測:按產品、疫苗類型、佐劑、給藥途徑、分銷管道、最終用戶和地區進行的全球分析Dengue Vaccine Market Forecasts to 2032 - Global Analysis By Product (Dengvaxia, Qdenga, and Other Pipeline Candidates), Vaccine Type, Treatment Adjuncts, Route of Administration, Distribution Channel, End User, and By Geography |
根據 Stratistics MRC 的數據,全球登革熱疫苗市場預計在 2025 年達到 4.8961 億美元,到 2032 年將達到 13.5891 億美元,預測期內複合年成長率為 15.7%。
登革熱疫苗是預防登革熱(一種蚊媒病毒性疾病)的處方免疫接種。疫苗能夠引發免疫反應,使人體產生保護性抗體,進而抵抗登革熱病毒。這些疫苗的主要目的是最大限度地降低感染風險,減輕病情嚴重程度,並避免住院。這些疫苗在疫情控制中發揮重要作用,尤其是在登革熱構成重大健康挑戰的登革熱流行地區。
公眾健康意識不斷增強
各國政府和非政府組織正在加強登革熱預防教育工作,尤其是在登革熱流行地區。數位平台和行動醫療應用程式正被用於傳播疫苗訊息和追蹤疫苗接種覆蓋率。隨著都市化和氣候變遷擴大蚊子棲息地,預防措施變得更加迫切。監測和診斷領域的技術創新使得早期發現和有針對性的疫苗接種策略成為可能。這種意識的提高正在推動對可靠且可及的登革熱疫苗的需求,以滿足不同人群的需求。
安全性和有效性問題
由於擔心疫苗安全性以及不同血清型疫苗療效的差異,疫苗在某些地區的推廣速度有所放緩。監管機構呼籲進行大規模臨床試驗,以檢驗疫苗的長期療效,尤其是兒童和老年族群。四種登革熱病毒株的複雜性對免疫抗原性一致性提出了挑戰。不利事件監測系統正在升級,以確保上市後監測和透明度。人工智慧臨床分析等新技術正在幫助完善療效模型,但公眾的懷疑仍然是一個障礙。這些因素導致一些國家採取謹慎的推廣策略,市場滲透速度緩慢。
下一代疫苗的開發
mRNA平台和重組DNA技術的進步使得免疫反應更具針對性和持久性。研究機構和生物技術公司正在合作開發適用於熱帶氣候的耐熱製劑。人工智慧和生物資訊學正在加速抗原設計和測試模擬,縮短開發時間。各國政府正在提供津貼和加速核准,以支持該領域的創新。隨著全球衛生重點轉向疫情防範,登革熱疫苗研發正獲得策略性發展動能。
經濟限制
負擔能力仍然是一個重大障礙,尤其是在低收入和高負擔地區。有限的醫療預算和相互競爭的優先事項往往會延遲疫苗的採購和分配。登革熱疫苗等複雜生技藥品的高昂製造成本影響了定價策略。供應鏈效率低和低溫運輸需求進一步加劇了偏遠地區的物流。模組化和分散式製造的新興趨勢旨在降低成本並改善可及性。如果沒有持續的資金籌措和國際支持,市場擴張可能會不均衡,並且容易受到經濟衝擊的影響。
COVID-19的影響
疫情擾亂了疫苗臨床試驗,並轉移了登革熱疫苗接種計畫的資源。封鎖和旅行限制推遲了現場測試和監管審查,從而推遲了產品上市。然而,新冠疫情加速了數位醫療的普及,包括遠端試驗監控和基於人工智慧的數據收集。疫情期間建立的緊急使用框架目前正在適應登革熱疫苗的核准。後疫情時代策略強調韌性供應鏈和綜合疾病監測系統,其中將登革熱作為優先事項。
預測期內,登革熱疫苗市場預計將成為最大的市場
由於監管部門的核准和完善的全球分銷網路,預計登革熱疫苗市場將在預測期內佔據最大市場佔有率。登革熱疫苗是唯一獲得廣泛許可的疫苗,已在多個國家(主要在亞洲和拉丁美洲)投入使用。正在進行的上市後研究正在改善其風險-效益狀況,尤其對於血清陽性族群。低溫運輸物流和數位追蹤技術的進步正在提高疫苗的可用性和可靠性。與公共衛生機構的夥伴關係正在擴大登革熱疫苗在學校免疫接種計畫中的覆蓋率。儘管過去存在爭議,但Dengvaxia強大的市場影響力和基礎設施支撐了其市場領先地位。
預測期內腸外藥物市場將以最高複合年成長率成長
預計在預測期內,腸外疫苗領域將達到最高成長率。注射劑可精準給藥,並融入現有的醫療保健工作流程。無針注射器和微陣列貼片等創新技術正在提高患者依從性並縮短給藥時間。低溫運輸最佳化和智慧包裝技術使疫苗腸外給藥在偏遠地區更可行。由於下一代登革熱候選疫苗的吸收特性穩定,臨床試驗越來越傾向腸外給藥。隨著醫療保健系統的現代化,腸外給藥正成為大規模疫苗接種的首選途徑。
預計亞太地區將在預測期內佔據最大的市場佔有率。印度、印尼和菲律賓等國家正在透過政府資助的宣傳活動擴大疫苗接種計畫。對生物技術基礎設施和本地製造業的投資正在減少對進口的依賴。行動醫療平台和人工智慧驅動的疾病地圖繪製正在提高疫苗部署的效率。全球製藥公司與區域參與者之間的策略聯盟正在加速技術轉移和監管協調。
在預測期內,北美預計將憑藉其尖端研發和積極的監管支持,實現最高的複合年成長率。美國和加拿大正在大力投資疫苗創新,包括基於mRNA的登革熱候選疫苗。人工智慧和機器學習正在整合到臨床試驗設計和即時療效監測中。監管機構正在簡化熱帶疾病疫苗的核准途徑,以加快疫苗的上市速度。官民合作關係正在資助與全球擴張一致的先進生產和分銷模式。隨著氣候變遷導致美國南部登革熱風險增加,北美正逐漸成為關鍵的成長前線。
According to Stratistics MRC, the Global Dengue Vaccine Market is accounted for $489.61 million in 2025 and is expected to reach $1358.91 million by 2032 growing at a CAGR of 15.7% during the forecast period. A dengue vaccine is a preventive immunization formulated to safeguard people from dengue fever, a viral illness transmitted by mosquitoes. By triggering an immune response, it enables the body to generate protective antibodies that help defend against the dengue virus. Its primary purpose is to minimize infection risks, reduce disease intensity, and prevent hospitalizations. This vaccine plays a vital role in controlling outbreaks, especially in dengue-endemic areas where the disease poses significant health challenges.
Growing public health awareness
Governments and NGOs are intensifying education efforts around dengue prevention, especially in endemic regions. Digital platforms and mobile health apps are being leveraged to disseminate vaccine information and track immunization coverage. As urbanization and climate change expand mosquito habitats, the urgency for preventive measures is rising. Technological innovations in surveillance and diagnostics are enabling earlier detection and targeted vaccination strategies. This growing consciousness is fostering demand for reliable and accessible dengue vaccines across diverse populations.
Safety and efficacy concerns
Concerns over vaccine safety and variable efficacy across serotypes are slowing adoption in certain regions. Regulatory bodies require extensive clinical trials to validate long-term outcomes, especially for pediatric and elderly populations. The complexity of dengue's four viral strains poses challenges for consistent immunogenicity. Adverse event monitoring systems are being upgraded to ensure post-marketing surveillance and transparency. Emerging technologies like AI-driven trial analytics are helping refine efficacy models, but public skepticism remains a hurdle. These factors contribute to cautious rollout strategies and delayed market penetration in some countries.
Development of next-generation vaccines
Advances in mRNA platforms and recombinant technologies are enabling more targeted and durable immune responses. Research institutions and biotech firms are collaborating on thermostable formulations suitable for tropical climates. AI and bioinformatics are accelerating antigen design and trial simulations, reducing development timelines. Governments are offering grants and fast-track approvals to support innovation in this space. As global health priorities shift toward pandemic preparedness, dengue vaccine R&D is gaining strategic momentum.
Economic constraints
Affordability remains a major barrier, particularly in low-income and high-burden regions. Limited healthcare budgets and competing priorities often delay vaccine procurement and distribution. Manufacturing costs for complex biologics like dengue vaccines are high, impacting pricing strategies. Supply chain inefficiencies and cold chain requirements further strain logistics in remote areas. Emerging trends in modular production and decentralized manufacturing aim to reduce overheads and improve access. Without sustained funding and international support, market expansion may be uneven and vulnerable to economic shocks.
Covid-19 Impact
The pandemic disrupted vaccine trials and diverted resources away from dengue immunization programs. Lockdowns and travel restrictions delayed field studies and regulatory reviews, slowing product launches. However, Covid-19 accelerated digital health adoption, including remote trial monitoring and AI-based data collection. Emergency use frameworks introduced during the pandemic are now being adapted for dengue vaccine approvals. Post-Covid strategies emphasize resilient supply chains and integrated disease surveillance systems that include dengue as a priority.
The dengvaxia segment is expected to be the largest during the forecast period
The dengvaxia segment is expected to account for the largest market share during the forecast period, due to its established regulatory approvals and global distribution footprint. It remains the only widely licensed dengue vaccine with multi-country deployment, especially in Asia and Latin America. Continuous post-marketing studies are refining its risk-benefit profile, particularly for seropositive individuals. Technological upgrades in cold chain logistics and digital tracking are enhancing its reach and reliability. Partnerships with public health agencies are expanding its coverage in school-based immunization programs. Despite past controversies, Dengvaxia's entrenched presence and infrastructure support its leading market position.
The parenteral segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the parenteral segment is predicted to witness the highest growth rate, driven by their proven delivery efficiency and immunogenicity. Injectable formats offer precise dosing and are compatible with existing healthcare workflows. Innovations in needle-free injectors and microarray patches are improving patient compliance and reducing administration time. Cold chain optimization and smart packaging technologies are making parenteral vaccines more viable in remote settings. Clinical trials are increasingly favoring parenteral delivery for next-gen dengue candidates due to consistent absorption profiles. As healthcare systems modernize, parenteral formats are becoming the preferred choice for mass immunization drives.
During the forecast period, the Asia Pacific region is expected to hold the largest market share propelled by high disease prevalence and robust public health initiatives. Countries like India, Indonesia, and the Philippines are scaling up vaccination programs through government-backed campaigns. Investments in biotech infrastructure and local manufacturing are reducing dependency on imports. Mobile health platforms and AI-driven disease mapping are enhancing vaccine deployment efficiency. Strategic collaborations between global pharma firms and regional players are accelerating technology transfer and regulatory harmonization.
Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, fuelled by cutting-edge R&D and proactive regulatory support. The U.S. and Canada are investing heavily in vaccine innovation, including mRNA-based dengue candidates. AI and machine learning are being integrated into clinical trial design and real-time efficacy monitoring. Regulatory agencies are streamlining approval pathways for tropical disease vaccines, encouraging faster market entry. Public-private partnerships are funding advanced manufacturing and distribution models tailored for global deployment. As climate change increases dengue risk in southern U.S. regions, North America is emerging as a key growth frontier.
Key players in the market
Some of the key players profiled in the Dengue Vaccine Market include Sanofi, Medigen Vaccine Biologics Corp., Takeda Pharmaceutical Company, Biological E. Limited, GlaxoSmithKline (GSK), Serum Institute of India, Bharat Biotech, Vabiotech, Merck & Co., Panacea Biotec, F. Hoffmann-La Roche Ltd., BioNet-Asia Co. Ltd., Novartis AG, Instituto Butantan, and Teva Pharmaceutical Industries Ltd.
In Sepetember 2025, Medigen Vaccine Biologics Corp (MVC) has signed a regional distribution agreement with the pharmaceutical company Substipharm Biologics to expand the market reach of enterovirus vaccine products in Southeast Asia. The two companies have finalized an exclusive distribution agreement for ENVACGEN(R) Enterovirus A71 (EV-A71) vaccine in Vietnam as the first country of launch.
In August 2025, Sanofi announces the completion of its acquisition of Vigil Neuroscience, Inc.. This acquisition strengthens Sanofi's early-stage pipeline in neurology with VG-3927, a novel, oral, small-molecule TREM2 agonist, which will be evaluated in a phase 2 clinical study in patients with Alzheimer's disease. In addition, the acquisition of Vigil's preclinical pipeline will further strengthen Sanofi's research in various neurodegenerative diseases.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.