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市場調查報告書
商品編碼
1725148
2032 年尿激酶市場預測:按類型、來源、給藥途徑、應用、最終用戶和地區進行的全球分析Urokinase Market Forecasts to 2032 - Global Analysis By Type (Urokinase Powder and Urokinase Solution), Source, Route of Administration, Application, End User and By Geography |
根據 Stratistics MRC 的數據,全球尿激酶市場預計在 2025 年達到 20.8 億美元,到 2032 年將達到 35 億美元,預測期內的複合年成長率為 7.7%。
尿激酶是一種血栓溶解酶,醫學上用於溶解體內的血栓。它是絲胺酸蛋白酶,最初來自人類尿液,但現在通常使用重組 DNA 技術生產。尿激酶將胞漿素原原轉化為胞漿素,並作為分解纖維蛋白(血塊的主要蛋白質組成)的酶。主要用於治療肺動脈栓塞、深層靜脈栓塞症、導管阻塞等。尿激酶作為纖溶酶原活化劑,在恢復阻塞血管的血流中起著重要作用,使其成為急診和介入醫學的重要治療選擇。
根據英國心臟基金會 2024 年的一篇報導,英國有 760 萬人患有心臟和循環系統疾病。
血栓性疾病盛行率不斷上升
由於對血栓溶解療法的需求增加,血栓疾病的盛行率不斷上升,推動了尿激酶市場的發展。尿激酶用於分解血栓,在治療肺動脈栓塞、深層靜脈栓塞症和急性心肌梗塞中發揮重要作用。隨著這些疾病在全球範圍內的盛行率上升,特別是在老年人口中,對有效的溶栓療法的需求也日益增加。這一趨勢有利於尿激酶市場並刺激其生產和應用的進一步發展。
醫療費用高昂
高昂的治療費用嚴重阻礙了尿激酶市場的成長,因為它限制了患者和醫療保健提供者獲得治療的機會,尤其是在中低收入地區。如此高的治療費用限制了尿激酶治療方法的廣泛使用,並導致對更便宜的替代療法的需求。此外,高成本對醫療預算造成壓力,阻礙了保險覆蓋,並限制了廣泛的臨床使用,最終減緩了市場擴張並抑制了溶栓療法的創新。
藥物傳輸技術進步
藥物輸送系統的技術進步對尿激酶市場產生了重大影響,提高了其治療效果和精確度。靶向輸送機制和基於奈米粒子的配方等技術創新有望提高生物有效性並減少副作用。這些進步提高了藥物針對特定部位的能力,最佳化了血栓和心臟病等疾病的治療。此外,控制釋放技術和個人化藥物傳遞系統有助於改善患者的治療效果,進而推動尿激酶市場的需求和成長。
出血併發症的風險
出血併發症的風險將嚴重阻礙尿激酶市場的成長。尿激酶是一種溶栓劑,極有可能引起內出血,尤其是對於有潛在疾病或服用抗凝血劑的患者。這些安全問題限制了醫療保健提供者對尿激酶的採用,並促使謹慎開藥。此外,監管限制和更安全替代藥物的可用性進一步限制了市場擴張,對需求和整體市場表現產生負面影響。
COVID-19的影響
COVID-19 疫情嚴重擾亂了尿激酶市場,導致擇期手術延遲、住院人數減少以及供應鏈中斷。在疫情高峰期,對非新冠相關治療(包括尿激酶等溶栓藥物)的需求下降。然而,隨著醫療保健系統的穩定和外科手術的恢復,市場開始復甦。此外,人們對 COVID-19 患者血栓併發症的認知提高間接支持了對抗凝血和溶栓療法的需求。
預計尿激酶溶液細分市場在預測期內將佔據最大佔有率
預計在預測期內,尿激酶溶液部分將佔據最大的市場佔有率。尿激酶溶液,尤其是靜脈注射和局部形式,因其能夠快速溶解血栓,改善肺動脈栓塞和深層靜脈栓塞症等患者的預後而受到青睞。醫院和醫療機構擴大採用尿激酶製劑以及正在進行的研究也對該領域的市場擴張產生了積極影響。
預計深層靜脈栓塞症領域在預測期內將以最高複合年成長率成長
由於血栓性疾病盛行率的上升以及對早期診斷和治療的認知的提高,預計深層靜脈栓塞症部分將在預測期內出現最高成長率。尿激酶是一種溶栓劑,廣泛用於深部靜脈栓塞(DVT)患者的溶栓治療,其需求日益成長。醫療基礎設施的進步和人口老化也促進了市場擴張。這一趨勢使 DVT 成為尿激酶市場持續成長和創新的關鍵驅動力。
預計亞太地區將在預測期內佔據最大的市場佔有率。這是由於心血管疾病的增加、認知的提高以及獲得先進治療的機會的改善推動了需求。這種成長正在刺激創新、鼓勵投資並改善開發中國家患者的治療效果。此外,政府支持和不斷擴大的醫療保健基礎設施正在加速市場滲透,使挽救生命的溶栓療法更容易獲得,最終有助於改善公共衛生並增強當地製藥業的前景。
在預測期內,由於人們對溶栓療法的認知不斷提高,預計北美將呈現最高的複合年成長率。醫療保健基礎設施的進步、大型製藥公司的存在以及支持性法律規範進一步推動了市場擴張。老年人口的成長和對微創治療的需求將推動基於尿激酶的療法的採用。這些因素的結合顯著改善了患者的治療效果,刺激了區域市場的成長和創新。
According to Stratistics MRC, the Global Urokinase Market is accounted for $2.08 billion in 2025 and is expected to reach $3.50 billion by 2032 growing at a CAGR of 7.7% during the forecast period. Urokinase is a thrombolytic enzyme used medically to dissolve blood clots in the body. It is a serine protease originally derived from human urine, but now commonly produced using recombinant DNA technology. Urokinase works by converting plasminogen to plasmin, an enzyme that breaks down fibrin, the primary protein component of blood clots. It is primarily used to treat conditions such as pulmonary embolism, deep vein thrombosis, and catheter blockages. As a fibrinolytic agent, urokinase plays a vital role in restoring blood flow in occluded vessels, making it a critical therapeutic option in emergency and interventional medicine.
According to 2024 article by British Heart Foundation, 7.6 million people are living in with heart and circulatory disease in UK.
Rising Prevalence of Thrombotic Disorders
The growing incidence of thrombotic disorders is propelling the urokinase market due to the heightened need for thrombolytic treatments. The enzyme urokinase, which is employed to break down blood clots, plays a vital role in the treatment of conditions like pulmonary embolism, deep vein thrombosis, and acute myocardial infarction. As the global prevalence of these disorders rises, particularly among aging populations, the demand for effective clot-dissolving treatments is increasing. This trend is benefiting the urokinase market and spurring further developments in its production and application.
High Treatment Costs
High treatment costs significantly hinder the growth of the urokinase market by limiting accessibility for patients and healthcare providers, particularly in low- and middle-income regions. These elevated expenses reduce the adoption of urokinase-based therapies, as more affordable alternatives are sought. Additionally, high costs strain healthcare budgets, discourage insurance coverage, and restrict widespread clinical use, ultimately slowing market expansion and impeding innovation in thrombolytic treatments.
Technological Advancements in Drug Delivery
Technological advancements in drug delivery systems have significantly impacted the Urokinase market by enhancing its therapeutic efficacy and precision. Innovations such as targeted delivery mechanisms and nanoparticle-based formulations ensure better bioavailability and reduced side effects. These advancements improve the drug's ability to target specific sites, optimizing the treatment of conditions like blood clots and heart attacks. Additionally, controlled release technologies and personalized drug delivery systems contribute to improved patient outcomes, driving demand and growth within the Urokinase market.
Risk of Bleeding Complications
The risk of bleeding complications significantly hinders the growth of the urokinase market. Urokinase, a thrombolytic agent, carries a high potential for causing internal bleeding, particularly in patients with underlying conditions or on anticoagulants. This safety concern limits its widespread adoption among healthcare providers, prompting cautious prescription practices. Additionally, regulatory restrictions and the availability of safer alternatives further restrain market expansion, negatively impacting demand and overall market performance.
Covid-19 Impact
The COVID-19 pandemic significantly disrupted the urokinase market due to delays in elective surgeries, reduced hospital admissions, and supply chain interruptions. Demand for non-COVID-related therapies, including thrombolytic agents like urokinase, declined during the peak of the pandemic. However, as healthcare systems stabilized and surgical procedures resumed, the market began recovering. Additionally, increased awareness of thrombotic complications in COVID-19 patients indirectly supported demand for anticoagulant and thrombolytic therapies.
The urokinase solution segment is expected to be the largest during the forecast period
The urokinase solution segment is expected to account for the largest market share during the forecast period because Urokinase solutions, particularly in intravenous and local delivery forms, are gaining preference due to their ability to rapidly dissolve blood clots, improving patient outcomes in conditions like pulmonary embolism and deep vein thrombosis. The growing adoption of urokinase solutions in hospitals and healthcare facilities, combined with ongoing research, is further fueling the segment's positive impact on market expansion.
The deep vein thrombosis segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the deep vein thrombosis segment is predicted to witness the highest growth rate, due to the rising incidence of thrombotic disorders and increased awareness of early diagnosis and treatment. Urokinase, a thrombolytic agent, is widely used to dissolve blood clots in DVT patients, leading to its growing demand. Advancements in healthcare infrastructure and an aging population further contribute to market expansion. This trend positions DVT as a key driver fueling sustained growth and innovation in the urokinase market.
During the forecast period, the Asia Pacific region is expected to hold the largest market share due to rising cardiovascular cases, increased awareness, and improved access to advanced therapies are driving demand. This growth is fostering innovation, encouraging investments, and improving patient outcomes across developing nations. Additionally, government support and expanding healthcare infrastructure are accelerating market penetration, making life-saving thrombolytic therapies more accessible, ultimately contributing to better public health and a stronger regional pharmaceutical landscape.
Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, owing to increasing awareness of thrombolytic therapies. Advancements in healthcare infrastructure, strong presence of key pharmaceutical players, and supportive regulatory frameworks further fuel market expansion. The growing geriatric population and demand for minimally invasive procedures enhance the uptake of urokinase-based treatments. Collectively, these factors are significantly improving patient outcomes and driving the regional market's growth and innovation.
Key players in the market
Some of the key players profiled in the Urokinase Market include Syner-Med Ltd., Microbix Biosystems Inc., Wuxi Green Pharmaceutical Co., Ltd., Jiangxi Haoran Bio-Pharma Co., Ltd., Medicure Inc., Lee's Pharmaceutical Holdings Ltd., Taj Pharmaceuticals Limited, Jiangsu Techpool Bio-Pharma Co., Ltd., Guangzhou Recomgen Biotech Co., Ltd., LGM Pharma, ScienCell Research Laboratories, Inc., BioVision, Inc., Abbott Laboratories, Enzo Life Sciences, Inc., Molecular Innovations, Inc., Prospec-Tany Technogene Ltd., Wuhan YZY Biopharma Co., Ltd., GenScript Biotech Corporation and Chymotech AS.
In August 2024, Abbott and Medtronic announced a significant global partnership, to integrate Abbott's FreeStyle Libre continuous glucose monitoring (CGM) technology with Medtronic's insulin delivery systems. This collaboration aims to enhance diabetes management by enabling automatic insulin adjustments based on real-time glucose data.
In June 2024, Abbott has partnered with the National Association of Community Health Centers (NACHC) to improve access to nutritious food and health services. The collaboration aims to enhance healthcare delivery and address the growing health challenges related to nutrition in underserved communities.