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市場調查報告書
商品編碼
1403517
掌腱膜攣縮症市場至2030年的預測:按疾病類型、治療、診斷、給藥途徑、分銷管道、最終用戶和地區的全球分析Dupuytren Disease Market Forecasts to 2030 - Global Analysis By Disease Type, Treatment, Diagnosis, Route of Administration, Distribution Channel, End User and By Geography |
根據 Stratistics MRC 的資料,2023年全球掌腱膜攣縮症市場規模為 44 億美元,預計到2030年將達到 68.6 億美元,預測期內年複合成長率為 6.6%。
掌腱膜攣縮症,也稱為Dupuytren氏攣縮,是一種影響手部和手指的疾病。其特徵是手掌皮膚下的結締組織增厚和硬化。掌腱膜攣縮症的主要特徵是在手掌上形成結節或腫塊,這些結節或腫塊可能會發展成組織索,將受影響的手指向內拉。
隨著世界人口老化,受掌腱膜攣縮症影響的人數自然也增加,特別是在該病患病率較高的地區。此外,認知的提高和診斷能力的提高有助於更準確、及時地識別掌腱膜攣縮症患者。總體而言,掌腱膜攣縮症的盛行率上升為改善患者照護和新治療方法的市場開拓創造了機會,推動了市場成長。
治療成本是掌腱膜攣縮症市場的一個重要抑制因素,影響了需求。切除術和筋膜切開術等手術介入以及某些藥物治療包括大量費用,包括住院費用、外科醫生費用和術後護理。此外,掌腱膜攣縮症有復發的可能性,需要額外的治療並隨著時間的推移增加患者的總費用。
治療方案的技術創新是掌腱膜攣縮症市場的關鍵驅動力,加速了需求。膠原蛋白酶注射劑的引進徹底改變了掌腱膜攣縮症的治療方法。膠原酶是一種分解收縮組織的酶,使受影響的手指伸直。這種非手術方法避免了切口和麻醉的需要,為患者提供了一種侵入性較小的治療選擇。
掌腱膜攣縮症在患者之間表現出很大的異質性,其嚴重程度、受影響的手腕關節和治療反應各不相同。這種變異性使得預測治療結果和為每個人選擇最合適的治療變得困難。在某些患者中,儘管經過治療,攣縮的改善可能有限或復發,需要額外的干涉措施或合併治療方法。因此,掌腱膜攣縮症市場的治療選擇有限,對市場成長構成挑戰。
COVID-19 的爆發對雙相疾病市場產生了重大影響,帶來了影響患者照護和市場動態的挑戰。醫療保健系統優先分配資源來應對這一流行病,擾亂了常規醫療服務並延遲了掌腱膜攣縮症的診斷和治療。此外,疫情期間的供應鏈中斷和製造挑戰影響 Dupuytren 獨特治療方法的可用性和分銷。
預計放射線治療領域將佔最大佔有率。放射線治療使用高能量輻射來瞄準和抑制與掌腱膜攣縮症相關的異常組織生長。這種非侵入性治療方法特別適用於疾病晚期的患者,其特徵是出現影響手部功能的攣縮和結節。當多個手指受到影響或手術後復發時尤其有效。
預計腸外給藥領域在預測期內將出現良好的成長。在掌腱膜攣縮症中,腸胃外給藥途徑在繞過胃腸道直接向患者體內提供治療性介入方面發揮著非常重要的作用。這種直接方法可確保治療藥物的快速吸收和分佈,在疾病症狀管理中發揮最佳功效。此外,腸胃外途徑最大限度地降低了藥物在胃腸道環境中分解和改變的風險,提高了生物有效性。
在估計期間,北美佔據了最大的市場佔有率。該地區擁有先進的醫療基礎設施、完善的法律規範以及掌腱膜攣縮症的高盛行率,尤其是在人口老化地區。該地區的醫療保健環境鼓勵採用先進的外科手術、注射治療和非侵入性選擇。此外,該地區的研究機構、製藥公司和醫療保健提供者之間的合作促進新治療方法的開發。
預計亞太地區在預測期內將實現盈利成長。該地區發生了重大轉變,採用了先進的醫療技術和治療方法掌腱膜攣縮症的方法。不斷增加的研究舉措、區域和國際醫療保健營業單位之間的合作以及不斷發展的醫療保健政策都有助於創新治療方法的開發和採用。該地區的市場開拓進一步受到經濟發展、醫療成本降低以及更注重以患者為中心的護理的推動。
According to Stratistics MRC, the Global Dupuytren Disease Market is accounted for $4.40 billion in 2023 and is expected to reach $6.86 billion by 2030 growing at a CAGR of 6.6% during the forecast period. Dupuytren's disease, also known as Dupuytren's contracture, is a medical condition that affects the hands and fingers. It is characterized by the thickening and tightening of the connective tissue beneath the skin in the palm of the hand. The primary feature of Dupuytren's disease is the development of nodules or lumps in the palm, which may progress to form cords of tissue that pull the affected fingers inward.
As the global population ages, particularly in regions with a higher prevalence of this condition, there is a natural rise in the number of individuals affected by Dupuytren's disease. Moreover, heightened awareness and improved diagnostic capabilities contribute to the more accurate and timely identification of Dupuytren's disease cases. Overall, the escalating incidence of Dupuytren's disease propels market growth by creating opportunities for improved patient care and the development of novel treatment modalities.
The cost of treatment serves as a notable restraint in the Dupuytren's disease market, impacting the demand. Surgical interventions, such as fasciectomy or fasciotomy, and certain pharmaceutical treatments involve substantial costs; include hospitalization, surgeon fees, and post-operative care. Moreover, the potential for recurrence in Dupuytren's disease necessitates additional treatments, amplifying the overall cost for patients over time.
Technological innovations in treatment options are a significant driver in the Dupuytren disease market, accelerating the demand. The introduction of collagenase injections has revolutionized the treatment of Dupuytren disease. Collagenase is an enzyme that can break down the contracted tissue, enabling the straightening of the affected fingers. This non-surgical approach avoids the need for incisions or anaesthesia and provides patients with a less-invasive treatment option.
Dupuytren disease exhibits significant heterogeneity among patients, with variations in disease severity, affected hand joints, and response to treatments. This variability makes it challenging to predict treatment outcomes and select the most appropriate intervention for each individual. Some patients may experience limited improvement or recurrence of contractures even after undergoing treatment, leading to the need for additional interventions or a combination of treatment approaches. Therefore, the limited treatment options in the dupuytren disease market pose a challenge to market growth.
The COVID-19 pandemic has significantly impacted the Dupuytren disease market, introducing challenges that have influenced both patient care and market dynamics. The healthcare system's prioritization of resources toward managing the pandemic has led to disruptions in routine medical services, delaying the diagnosis and treatment of Dupuytren disease. Additionally, supply chain disruptions and manufacturing challenges during the pandemic have affected the availability and distribution of Dupuytren-specific treatments.
The radiation therapy segment is estimated to hold the largest share. Radiation therapy involves the use of high-energy radiation to target and reduce abnormal tissue growth associated with Dupuytren's disease. This non-invasive treatment modality is particularly considered for individuals with advanced stages of the disease, characterized by contractures and nodules impacting hand function. It is especially beneficial in cases where multiple fingers are affected or when the disease recurs after surgery.
The parenteral segment is anticipated to have lucrative growth during the forecast period. In Dupuytren's disease the parenteral route of administration plays a pivotal role in delivering therapeutic interventions directly into the patient's system, bypassing the gastrointestinal tract. This direct approach ensures rapid absorption and distribution of the therapeutic agent, allowing for optimal efficacy in managing the disease's symptoms. Moreover, the parenteral route minimizes the risk of degradation or alteration of the drug in the gastrointestinal environment, enhancing its bioavailability.
North America commanded the largest market share during the extrapolated period. The region comprises advanced healthcare infrastructure, a well-established regulatory framework, and a high prevalence of Dupuytren's disease, particularly in the aging population. The region's healthcare landscape encourages the adoption of advanced surgical procedures, injectable treatments, and non-invasive options. Moreover, collaborations between research institutions, pharmaceutical companies, and healthcare providers contribute to the development of novel therapies in this region.
Asia Pacific is expected to witness profitable growth over the projection period. In this region, there is a notable shift toward embracing advanced medical technologies and therapies for Dupuytren's disease. Increased research initiatives, collaborations between regional and international healthcare entities, and evolving healthcare policies contribute to the development and adoption of innovative treatment options. The market's growth in this region is further propelled by economic development, improved healthcare affordability, and a heightened focus on patient-centric care.
Some of the key players in the Dupuytren Disease Market include Pfizer Inc, AstraZeneca, Endo International plc, LEO Pharma A/S, Spear Pharmaceuticals, Hikma Pharmaceuticals PLC, Bristol-Meyers Squibb Company, Fresenius Kabi AG, GSK plc, Actiza Pharmaceutical Private Limited, Nantong Jinghua Pharmaceutical Co., Ltd, Novartis AG, Bayer AG., Johnson & Johnson Services Ltd. and Aurobindo Pharma.
In August 2023, Hikma Pharmaceuticals PLC (Hikma), the multinational pharmaceutical company, announces a new strategic partnership and exclusive licensing agreement with SK Biopharmaceuticals, a global biotech company focused on the development of treatments for central nervous system (CNS) disorders and oncology, for the Middle East and North Africa.
In January 2022, Pfizer Inc. and BioNTech SE announced a new research, development and commercialization collaboration to develop a potential first mRNA-based vaccine for the prevention of shingles, a debilitating, disfiguring and painful disease that impacts about one in three people in the United States during their lifetime.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.