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市場調查報告書
商品編碼
1403510
2030 年人類血小板裂解物市場預測:按藥物類型、給藥途徑、配銷通路、最終用戶和地區進行的全球分析Human Platelet Lysate Market Forecasts to 2030 - Global Analysis By Drug Type, Route of Administration, Distribution Channel, End User and By Geography |
根據 Stratistics MRC 的數據,2023 年全球人血小板裂解物市場規模為 5,375 萬美元,預計到 2030 年將達到 8,029 萬美元,預測期內複合年成長率為 5.9%。
人類血小板裂解物 (HPL) 是一種源自人類血小板的細胞培養補充品。含有血小板衍生生長因子(PDGF)、轉化生長因子BETA(TGF-B)和類胰島素生長因子(IGF)等生長因子,以及促進細胞存活和刺激組織再生的各種蛋白質。此外,與牛(FBS) 等傳統細胞培養補充品相比,它具有許多優勢。 HPL 需求不斷成長是由於多種促進因素,包括其安全性、效率和道德考慮。
美國國家醫學圖書館發布的資料表明,人類血小板裂解物 (hPL) 的製造成本比牛更昂貴,而胎牛血清是人類血小板裂解物 (hPL) 的替代選擇。
人類血小板裂解物因富含細胞生長和增殖所必需的生長因子和細胞激素而聞名,已成為傳統血清培養基的絕佳替代品。它支持細胞增殖、維持細胞特性和促進組織再生的能力使其在再生醫學、幹細胞研究和組織工程中越來越多的採用。此外,對個人化醫療、基於細胞的治療方法的日益關注以及基於細胞培養的藥物研發發現的進步進一步增加了對人類血小板裂解物的需求。因此,將促進市場的成長。
人類血小板裂解物經歷了複雜的製造過程,包括收集、處理和品管,導致與傳統的基於血清的培養基相比,製造成本更高。如此高的成本限制了細胞培養應用中廣泛商業性用途的承受能力和可用性,並可能阻礙其採用。結果,市場擴張受到阻礙。
人類血小板裂解物富含細胞增生和組織再生必需的生長因子和細胞激素,完美滿足再生治療的要求。隨著再生醫學的不斷發展,HPL 已成為細胞培養中的重要輔助劑,可支持細胞增殖並維持組織再生所需的細胞特性。此外,其促進創傷治療、刺激組織修復和幫助開發基於細胞的治療方法的能力使人類血小板裂解物成為再生醫學應用中的寶貴成分。
儘管與牛(FBS) 相比,異種污染減少,但人類血小板裂解物具有人源產品傳播病原體的潛在風險。細菌和病毒等污染物可能會損害人類血小板裂解物的品質和安全性,影響其在研究和臨床環境中細胞培養應用的適用性。因此,這是市場拓展的主要障礙。
COVID-19 大流行最初造成了醫療保健行業的混亂和捐血限制,影響了 HPL 製造的原料的可得性。供應鏈中斷和實驗室活動減少擾亂了 HPL 的製造和分銷。然而,這場大流行凸顯了基於細胞的療法的重要性,並增加了人們對 HPL 發揮關鍵作用的再生醫學和細胞培養應用的興趣。隨著醫療保健產業的適應,隨著細胞治療方法研究重點的增加,市場已經捲土重來,這可能會進一步推動對 HPL 的需求。
據估計,基於肝素的人類血小板裂解物部分佔最大佔有率。肝素用於防止血小板採集和 HPL 製造過程中發生凝血,確保維持血小板完整性和生物活性。這種專門的 HPL 透過支持細胞生長、增殖和活力,為細胞培養應用帶來好處。肝素配方可增強 HPL 功能,特別有益於各種生物醫學領域,例如再生醫學、幹細胞研究和組織工程,在這些領域中,維持血小板生物活性對於獲得最佳細胞培養結果至關重要。
預計醫院藥局業務在預測期內將出現良好成長。醫院藥局是向醫療機構、臨床醫生和研究人員提供人類血小板溶解產品的重要中介機構。這些藥房在為再生醫學、細胞治療和研究等各種醫療應用提供人類血小板裂解物方面發揮著至關重要的作用。此外,這些藥房確保人類血小板裂解物產品的可用性、品質和及時分發,促進其在臨床環境和醫院實驗室中的使用。
由於生物醫學研究活動的活性化、再生醫學投資的增加以及對細胞療法的日益關注,亞太地區在預測期內佔據了最大的市場佔有率。中國、日本、韓國和印度等國家透過利用醫療基礎設施和研究舉措的進步,為 HPL 市場的成長做出了重大貢獻。此外,該地區蓬勃發展的生物製藥產業,加上其對個人化醫療和再生療法的關注,為HPL的採用提供了重要的機會,使亞太地區成為HPL在多種生物醫學應用中應用的重要場所。 。
由於先進的醫療基礎設施、強勁的生物製藥行業以及對生物醫學研究的大量投資,預計北美在預測期內將實現盈利成長。對個人化醫療的重視和對細胞療法日益成長的需求正在推動 HPL 在各種生物醫學應用中的使用。此外,北美已成為以尖端研發為特徵的關鍵地區,並為 HPL 在生物醫學研究和臨床環境中廣泛採用奠定了堅實的基礎。
According to Stratistics MRC, the Global Human Platelet Lysate Market is accounted for $53.75 million in 2023 and is expected to reach $80.29 million by 2030 growing at a CAGR of 5.9% during the forecast period. Human Platelet Lysate (HPL) is a cell culture supplement derived from human blood platelets. It contains growth factors like platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-B), insulin-like growth factor (IGF), and various other proteins that promote cell survival and stimulate tissue regeneration. Moreover, it offers numerous advantages over traditional cell culture supplements like foetal bovine serum (FBS). The growing demand for HPL can be attributed to several driving factors, including its safety, efficiency, and ethical considerations.
According to data published on National Library of Medicine, stated that human platelet lysate (hPL) has higher production cost than foetal bovine serum, which is an alternative option of human platelet lysate (hPL).
Human platelet lysate, renowned for its rich composition of growth factors and cytokines essential for cell growth and proliferation, has emerged as a superior alternative to traditional serum-based media. Its ability to support cell expansion, maintain cellular properties, and promote tissue regeneration has led to increased adoption in regenerative medicine, stem cell research, and tissue engineering. Moreover, the heightened focus on personalised medicine, cell-based therapies, and advancements in drug discovery utilising cell cultures further amplifies the need for human platelet lysate. Therefore, it will propel market growth.
The complex manufacturing process involving the collection, processing, and quality control measures for human platelet lysate results in elevated production expenses compared to traditional serum-based media. These higher costs limit its affordability and accessibility for widespread commercial use in cell culture applications, potentially hindering its adoption. As a result, it will hamper market expansion.
The human platelet lysate's rich composition of growth factors and cytokines essential for cell growth and tissue regeneration aligns perfectly with the requirements of regenerative therapies. As regenerative medicine continues to evolve, HPL emerges as a crucial supplement in cell culture, supporting cell proliferation and maintaining cellular properties necessary for tissue regeneration. Furthermore, its ability to enhance wound healing, stimulate tissue repair, and aid in the development of cell-based therapies positions human platelet lysate as a valuable component in regenerative medicine applications.
Despite reduced xenogeneic contamination compared to foetal bovine serum (FBS), human platelet lysate carries the potential risk of pathogen transmission from human-derived products. Contaminants, such as bacteria or viruses, could compromise the quality and safety of human platelet lysate, impacting its suitability for cell culture applications in research and clinical settings. Hence, it acts as a significant barrier to market expansion.
The COVID-19 pandemic initially caused disruptions in the healthcare sector and restrictions on blood donations, which affected the availability of raw materials for HPL production. Supply chain disruptions and reduced laboratory activities hindered its manufacturing and distribution. However, the pandemic underscored the importance of cell-based therapies, boosting interest in regenerative medicine and cell culture applications where HPL plays a crucial role. As the healthcare sector adapted, the market witnessed a resurgence due to increased research focus on cell-based treatments, potentially driving further demand for HPL.
The heparin-based human platelet lysate segment is estimated to hold the largest share. Heparin serves to prevent clotting during platelet collection and HPL production, ensuring the maintenance of platelet integrity and bioactivity. This specialised variant of HPL offers advantages in cell culture applications by supporting cell growth, proliferation, and viability. The inclusion of heparin enhances the functionality of HPL, making it particularly beneficial in various biomedical fields, including regenerative medicine, stem cell research, and tissue engineering, where uninterrupted platelet bioactivity is essential for optimal cell culture outcomes.
The hospital pharmacies segment is anticipated to have lucrative growth during the forecast period. Hospital pharmacies serve as crucial intermediaries, providing human platelet lysate products to healthcare facilities, clinicians, and researchers. These pharmacies play a pivotal role in supplying human platelet lysate for various medical applications, including regenerative medicine, cell therapy, and research endeavours. Moreover, they ensure the availability, quality, and timely distribution of human platelet lysate products, facilitating their use in clinical settings and research laboratories within hospitals.
Asia Pacific commanded the largest market share during the extrapolated period due to rising biomedical research activities, increasing investments in regenerative medicine, and a growing focus on cell-based therapies. Countries such as China, Japan, South Korea, and India are prominent contributors to HPL market growth, leveraging advancements in healthcare infrastructure and research initiatives. Furthermore, the region's burgeoning biopharmaceutical industry, combined with the emphasis on personalised medicine and regenerative therapies, offers substantial opportunities for HPL adoption, shaping the Asia-Pacific region as a significant hub for HPL utilisation in diverse biomedical applications.
North America is expected to witness profitable growth over the projection period due to advanced healthcare infrastructure, a robust biopharmaceutical industry, and substantial investments in biomedical research. Growing emphasis on personalised medicine and the escalating demand for cell-based therapies bolster the utilisation of HPL in various biomedical applications. Furthermore, North America stands as a key region, characterised by its cutting-edge developments and a strong foundation for the widespread adoption of HPL in biomedical research and clinical settings.
Some of the key players in the Human Platelet Lysate Market include Abbott Laboratories, Astrazeneca Plc., Acella Pharmaceuticals LLC, Cipla Limited, Glenmark Pharmaceuticals Limited, Dabur India Ltd, Johnson and Johnson, Glenmark Pharmaceuticals Limited, Merck KGaA, Pfizer Inc., Novartis International AG, Sanofi SA, Vernalis plc, Aurobindo Pharma Ltd, The Himalaya Drug Company, Beckman Coulter Inc., Sun Pharmaceutical Industries Ltd., Reckitt Benckiser Group PLC, Acadia Pharmaceuticals Inc. and Biocon.
In June 2023, PL BioScience GmbH entered into a Patent License and Assignment Agreement with French company Macopharma S.A.S., granting PL BioScience a worldwide license under Macopharma's patents and introducing PL BioScience to Macopharma's HPL customers for future orders.
In August 2022, StemCyte, Inc. obtained approval from U.S. FDA for their Phase II clinical trial for Post-COVID Syndrome using umbilical cord blood stem cell therapy.
In June 2021, Captivate Bio has signed a partnership agreement with PL BioScience GmbH to exclusively distribute ELAREM human platelet lysate products in the US and Canada, expanding their HPL offerings and enhancing PL BioScience's market presence in North America.