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市場調查報告書
商品編碼
1403461
2030 年微生物組定序服務市場預測:按類型、服務、技術、應用、最終用戶和地區進行的全球分析Microbiome Sequencing Services Market Forecasts to 2030 - Global Analysis By Type, Service, Technology, Application, End User and By Geography |
根據 Stratistics MRC 的數據,2023 年全球微生物組定序服務市場規模將達到 15.4 億美元,預計到 2030 年將達到 36.1 億美元,預測期內複合年成長率為 12.9%。
微生物組定序服務分析樣本中微生物的 DNA,揭示生活在特定環境(例如人類腸道)中的不同微生物群落的詳細資訊。這對於推進個人化醫療、疾病診斷以及理解微生物組與各種生態系統之間複雜的相互作用至關重要。這些服務可識別和量化微生物種類,並幫助研究人員和臨床醫生了解微生物組的組成和功能。
澳洲癌症協會2022年資料更新估計,2022年澳洲將新診斷出162,163例癌症病例,其中男性88,982例,女性73,181例。
生物製藥公司越來越認知到微生物組在人類健康和疾病中發揮的關鍵作用,為標靶治療和精準醫療方法的發展鋪平了道路。生物製藥公司正在利用微生物組定序進行臨床前和臨床試驗,以了解治療治療性介入對微生物生態系統的影響。此外,對腸道微生物組的探索尤其因其調節藥物代謝、功效和安全性的潛力而受到關注,從而推動了該市場的規模。
小型研究機構、學術實驗室和新興企業面臨獨特的財務挑戰,由於成本高昂,他們無法徹底實施微生物組定序服務。這些高成本加劇了研究人員和組織的經濟障礙,包括樣本採集、DNA 提取、文庫製備和資料分析。此外,微生物組分析的複雜性需要先進的定序技術和生物資訊學知識,增加了這些服務的整體高成本,阻礙了該市場的規模。
技術的進步使研究人員能夠產生大量資料,有助於更全面地了解不同生態系統中的微生物群落。次世代定序儀(NGS)平台、Illumina和Thermo Fisher等技術大大增加了微生物組定序的深度和廣度。此外,提高的定序準確性、更長的讀長和增加的通量有助於識別和表徵更廣泛的微生物物種,從而推動該市場的擴張。
不同平台和服務供應商之間的協議、方法和資料分析程序缺乏統一性,為比較和解釋結果帶來了挑戰。這種變異性可能導致微生物群落分析的不一致。此外,缺乏樣本採集、DNA 萃取和定序文庫製備的標準化方法可能會對微生物組資料造成偏差和錯誤。這不僅影響學術研究,也影響微生物組定序向臨床應用和法律規範的過渡,阻礙市場成長。
COVID-19 的爆發以多種方式對微生物組定序服務市場產生了負面影響。供應鏈中斷、物流挑戰和實驗室活動限制阻礙了微生物組定序服務的無縫運作。許多研究機構和生技公司面臨財務困難,進一步限制了微生物組研究和定序服務的投資。此外,臨床試驗和學術研究活動減少了學術和工業環境中對微生物組定序服務的需求,阻礙了該市場的成長。
全基因組定序領域預計將在估計和預測期間佔據最大佔有率,因為它能夠獲得廣泛的遺傳資訊,從而能夠檢測微生物群落內的稀有物種和變異。此外,該技術還能對生物體的整個 DNA 進行定序,從而可以詳細了解其基因組成、功能元件和潛在的毒力因子。該技術有助於加速發現並指導治療性介入,從而推動該領域的成長。
連接定序(SBL)領域預計在預測期內複合年成長率最高。在 SBL 中,DNA 片段使用特定的接頭連接形成串聯結構。這提供了諸如高精度、長讀長以及從困難的基因組區域檢索資訊的能力等優點。此外,研究人員和服務供應商可以全面了解微生物基因組,幫助了解群落動態、功能潛力和宿主-微生物組相互作用。
人們越來越認知到微生物組對健康和疾病的影響,再加上精準醫療和個體化醫療保健的重要性日益增加,在估計期間佔據了最大的市場佔有率。中國、日本、韓國和印度等國家正在促進研究機構、生技公司和定序服務供應商之間的合作。此外,隨著研究能力和基礎設施的不斷加強,高通量定序技術和生物資訊能力的進步進一步推動了該地區的成長。
預計歐洲在預測期內的複合年成長率最高。歐洲各地的多樣化人口為微生物組研究提供了豐富的環境,使研究人員能夠研究微生物組成的變化及其對區域健康模式的影響。此外,Illumina, Inc.、Macrogen, Inc.、Genewiz 和 Eurofins Scientific 等主要企業為個人化醫療、農業實踐和對微生物生態系統的了解做出了重大貢獻,正在推動該地區的擴張。
According to Stratistics MRC, the Global Microbiome Sequencing Services Market is accounted for $1.54 billion in 2023 and is expected to reach $3.61 billion by 2030 growing at a CAGR of 12.9% during the forecast period. Microbiome sequencing services analyze the DNA of microorganisms in a sample to reveal details about the diverse community of microbes living in a particular environment, like the human gut. It is crucial for personalized medicine, disease diagnostics, and advancing our understanding of the intricate interplay between microbiota and various ecosystems. These services identify and quantify microbial species, helping researchers and clinicians understand the microbiome's composition and function.
According to the data updated by Cancer Australia in 2022, it was estimated that 162,163 new cases of cancer would be diagnosed in Australia in 2022, out of which 88,982 would be males and 73,181 females.
Biopharmaceutical companies are increasingly recognizing the pivotal role of the microbiome in influencing human health and disease, paving the way for the development of targeted therapies and precision medicine approaches. Biopharmaceutical companies leverage microbiome sequencing to conduct preclinical and clinical trials, aiming to understand the impact of therapeutic interventions on microbial ecosystems. Furthermore, the exploration of the gut microbiome, in particular, has garnered attention for its potential in modulating drug metabolism, efficacy, and safety, which is boosting this market size.
Smaller research institutions, academic laboratories, and startups face unique financial challenges that prevent their capacity to conduct thorough microbiome sequencing services due to high costs. Financial obstacles for researchers and organizations are made worse by these high costs, which include sample collection, DNA extraction, library preparation, and data analysis. Additionally, the complexity of microbiome analysis, which necessitates sophisticated sequencing technologies and bioinformatics knowledge, adds to the overall high cost of these services, which is hindering this market size.
The technological strides enable researchers to generate vast amounts of data, facilitating a more comprehensive understanding of microbial communities within diverse ecosystems. Technologies such as next-generation sequencing (NGS) platforms, Illumina's, and Thermo Fisher's offerings have significantly enhanced the depth and breadth of microbiome sequencing. Furthermore, improved sequencing accuracy, longer read lengths, and increased throughput contribute to the identification and characterization of a wider range of microbial species, thereby propelling this market expansion.
The lack of uniformity in protocols, methodologies, and data analysis procedures across different platforms and service providers introduces challenges in comparing and interpreting results. This variability can lead to inconsistencies in microbial community profiling. Furthermore, the absence of standardized practices in sample collection, DNA extraction, and sequencing library preparation can contribute to biases and errors in microbiome data. This not only affects academic research but also impacts the translation of microbiome sequencing into clinical applications and regulatory frameworks, hindering the market's growth.
The COVID-19 pandemic has negatively impacted the microbiome sequencing services market in various ways. Disruptions in supply chains, logistical challenges, and restrictions on laboratory activities have impeded the seamless operation of microbiome sequencing services. Many research institutions and biotechnology companies faced financial constraints, further limiting investments in microbiome studies and sequencing services. Additionally, clinical trials and academic research activities decreased demand for microbiome sequencing services in both academic and industrial settings, impeding this market's growth.
The whole-genome sequencing segment is estimated to hold the largest share during the forecast period, due to its ability to capture a broad spectrum of genetic information, enabling the detection of rare species and variations within microbial communities. Additionally, this technique involves sequencing the entire DNA of an organism, providing a detailed understanding of its genetic makeup, functional elements, and potential virulence factors. It is instrumental in fueling discoveries and guiding therapeutic interventions, thereby driving this segment's growth.
The sequencing by ligation (SBL) segment is anticipated to have highest CAGR during the forecast period. In SBL, DNA fragments are ligated together using specific adapters, forming a concatemeric structure. This offers advantages such as high accuracy, long read lengths, and the ability to capture information from challenging genomic regions. In addition, researchers and service providers obtain comprehensive insights into microbial genomes, aiding in the understanding of community dynamics, functional potential, and host-microbiome interactions, which are boosting this market expansion.
Asia Pacific commanded the largest market share during the extrapolated period owing to increasing awareness of the microbiome's impact on health and disease, coupled with a rising emphasis on precision medicine and personalized healthcare. Countries like China, Japan, South Korea, and India foster collaborations between research institutions, biotechnology companies, and sequencing service providers. In addition, as research capabilities and infrastructure continue to strengthen the advancements in high-throughput sequencing technologies and bioinformatics capabilities further propel the region's growth.
Europe is expected to witness highest CAGR over the projection period. The diverse population across Europe provides a rich landscape for microbiome studies, enabling researchers to explore variations in microbial compositions and their impact on regional health patterns. Key players such as Illumina, Inc., Macrogen, Inc., Genewiz, and Eurofins Scientific also contribute significantly to advancements in personalized medicine, agricultural practices, and our understanding of microbial ecosystems, thus driving this region's expansion.
Some of the key players in the Microbiome Sequencing Services Market include DNA Genotek Inc., Thermo Fisher Scientific Inc., Illumina, Inc., Metabiomics, CosmosID, Zymo Research, Corporation, PerkinElmer, Inc., BGI Genomics Co., Ltd., Rancho Biosciences, Baseclear BV, Diversigen, Inc., Merieux Nutrisciences Corporations, Clinical Microbiomics AS, Bio-Rad Laboratories, Inc. and Genewiz Inc.
In November 2023, Illumina Inc., a global leader in DNA sequencing and array-based technologies announced the launch of the Global Health Access Initiative to support access to pathogen sequencing tools for public health in low- and middle-income countries (LMICs).
In October 2023, Thermo Fisher Scientific, the world leader in serving science, has introduced the Thermo Scientific™ Meridian™ EX System- an electron-beam-based failure analysis solution designed to enable precise fault localization on advanced semiconductor logic technologies.
In July 2023, Bio-Rad Laboratories, Inc. announced that the companies have agreed to settle their patent dispute pending in the U.S. District Court of Delaware pursuant to a global settlement and patent cross-licensing agreement relating to digital PCR technology.