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市場調查報告書
商品編碼
1401981
2030 年胜肽合成市場預測:按產品、技術、應用、最終用戶和地區進行的全球分析Peptide Synthesis Market Forecasts to 2030 - Global Analysis By Product (Equipment, Reagents, Consumables and Other Products), Technology, Application, End User and By Geography |
根據Stratistics MRC預測,2023年全球胜肽合成市場規模將達51億美元,預計2030年將達到102億美元,預測期內複合年成長率為10.2%。
形成胜肽(透過胜肽鍵連接的胺基酸短鏈)的化學過程稱為胜肽合成。胺基酸必須按照預定的順序階段組裝,反應的控制通常需要保留特定的官能基。合成勝胜肽有多種方法,包括固相合成、溶液相合成和重組DNA技術。
據 ClinicalTrials.gov 稱,正在開發 21 種胜肽藥物來治療 COVID-19,其中 15 種用於急性呼吸窘迫症候群(ARDS),這是一種肺部無法為身體重要器官提供足夠氧氣的疾病是一種合成勝胜肽,用於治療SARS-COV-2感染引起的呼吸道疾病。
個體化藥物的開發
隨著個體化醫療的出現,胜肽合成領域預計將顯著成長。個體化醫療的理念是透過根據特定患者情況客製化勝胜肽的能力來實現的。胜肽提供實現個體化治療計劃所需的標靶性、客製性和特異性。隨著個人化醫療的不斷發展和普及,對胜肽合成技術、服務和產品的需求預計將急劇增加。
有關給藥的問題
由於胃腸道吸收較差,大多數治療性胜肽透過腸胃外途徑給藥。胜肽藥物的口服生物利用度有限,主要是由於全身性酵素的分解。此外,它們的大分子量和帶電官能基會抑制吸收。由於這些特性,大多數給藥胜肽的生物利用度有限且半衰期短。因此,這對市場來說是一個挑戰。
罕見疾病治療方法的進展
胜肽有可能治療罕見疾病和不尋常的遺傳問題。隨著個體化醫療的出現,胜肽合成領域具有巨大的成長潛力。胜肽提供實現個體化治療計劃所需的標靶化、客製性和特異性。隨著個人化醫療的不斷發展和普及,對胜肽合成技術、服務和產品的需求預計將急劇增加。
精製和品管
為了使研究和治療應用有效,必須獲得高純度的胜肽。高效液相層析(HPLC) 是一種精製技術,但它可能非常耗時,並且必須針對每個胜肽序列進行最佳化。需要採取品管步驟來確保合成的胜肽準確、一致和安全。對於市場來說,維持有效的精製程序和高品質標準可能很困難。
這次疫情擾亂了世界各地的供應線,影響了胜肽合成所需原料和設備的可得性。合成勝胜肽的總分佈和可得性受到生產和出貨延誤的影響。大流行使醫療保健的重點發生了重大轉變。對與 COVID-19 研究相關的一些胜肽類藥物和疫苗的需求可能增加,而非必要醫療保健服務的中斷可能會減少對其他胜肽產品的需求。
預計試劑細分市場在預測期內將是最大的
預計試劑細分市場將成為預測期內最大的細分市場。胜肽合成過程將胺基酸化學結合形成胜肽。透過使用促進更快、更有效胜肽鍵形成的特定化學物質可以減少合成時間。透過減少副作用和污染物,並使用適當的試劑,您可以獲得更高純度的胜肽。某些試劑具有高度選擇性,因此有助於胺基酸的精確偶聯,而不會發生不良反應。
製藥和生物技術公司領域預計在預測期內複合年成長率最高
製藥和生物技術公司領域預計在預測期內複合年成長率最高。胜肽療法因其低毒性、高效和成本效益而成為更多研究和開發的主題。胜肽合成儀的快速技術進步和強大的胜肽治療產品線是推動製藥和生物技術公司胜肽合成產業的主要因素。
預計北美在預測期內將佔據最大的市場佔有率。客製化療法生產的擴大、基因組學和蛋白質組學領域的深入研究以及對創建基於結構的藥物設計的投資增加正在支持該地區的市場。此外,由於人們對易於使用的胜肽合成方法的認知不斷提高,預計市場將會擴大。
預計亞太地區在預測期內將維持最高的複合年成長率。由於主要參與者的投資增加,預計該市場將顯著開拓。此外,該地區市場的推動因素包括新型胜肽療法意識的增強、醫療保健成本的上升、更先進的醫療設施的可用性以及行業主要參與者為創造新的胜肽合成而進行的大量投資技術,預計將隨著投資而成長。
According to Stratistics MRC, the Global Peptide Synthesis Market is accounted for $5.1 billion in 2023 and is expected to reach $10.2 billion by 2030 growing at a CAGR of 10.2% during the forecast period. The chemical process of forming peptides, which are short chains of amino acids joined by peptide bonds, is known as peptide synthesis. It entails assembling amino acids step-by-step in a predetermined order, and controlling the reaction frequently necessitates the preservation of particular functional groups. There are several ways to synthesize peptides, including solid-phase synthesis, solution-phase synthesis, and recombinant DNA technology.
According to Clinical Trials.gov, 21 peptide drugs were in development for the treatment of COVID-19, including 15 synthetic peptides for acute respiratory distress syndrome (ARDS), a life-threatening condition in which the lungs are unable to provide enough oxygen to the body's vital organs, and other respiratory illnesses caused by SARS-Cov-2 infection.
Development of personalized medicines
The peptide synthesis sector has significant growth prospects due to the emergence of customized medicine. The idea of customized medicine is made possible by the ability to customize peptides to fit certain patient profiles. They provide the necessary targeting, customisation, and specificity to enable individualized treatment plans. It is anticipated that the need for peptide synthesis technology, services, and products will increase dramatically as personalized medicine continues to develop and gain popularity.
Problems related to the administrative route
The majority of therapeutic peptides are administered by the parenteral route because of insufficient absorption from the gastrointestinal tract. Peptide medications have a limited oral bioavailability mostly due to pre-systemic enzymatic breakdown. Additionally, the large molecular weight and charged functional groups of these medicines sometimes impede their absorption. These features result in the majority of peptides taken orally having limited bioavailability and brief half-lives. Hence, it can be considered a challenge for the market.
Advancement in therapeutics for rare diseases
Peptides could be able to cure orphan illnesses and unusual genetic problems. The peptide synthesis sector has significant growth prospects due to the emergence of customized medicine. Peptides provide the necessary targeting, customisation, and specificity to enable individualized treatment plans. It is anticipated that the need for peptide synthesis technology, services, and products will increase dramatically as personalized medicine continues to develop and gain popularity.
Purification and quality control
Peptides must be obtained with a high degree of purity in order for research and therapeutic applications to be effective. High-performance liquid chromatography (HPLC) is one of the purification techniques that might take a long time and need to be optimized for every peptide sequence. For synthesized peptides to be accurate, consistent, and safe, quality control procedures are necessary. The market may find it difficult to maintain effective purification procedures and high standards of quality.
The pandemic affected the availability of raw materials and equipment required for peptide synthesis by upsetting supply lines around the world. The total distribution and availability of synthesized peptides were impacted by production and shipping delays. The pandemic caused a major shift in the focus of healthcare. Demand for some peptide-based medications or vaccines associated with COVID-19 research may have increased, while interruptions in non-essential healthcare services may have resulted in a decline in demand for other peptide products.
The reagents segment is expected to be the largest during the forecast period
The reagents segment is expected to be the largest during the forecast period. The process of peptide synthesis entails joining amino acids chemically to form peptides. Synthesis times can be shortened by using certain chemicals that promote quicker and more effective peptide bond formation. By reducing side effects and contaminants, using the right reagent can result in a peptide that is more pure. Certain reagents help with the precise coupling of amino acids without producing undesirable reactions since they are very selective.
The pharmaceutical and biotechnology companies segment is expected to have the highest CAGR during the forecast period
The pharmaceutical and biotechnology companies segment is expected to have the highest CAGR during the forecast period. Peptide treatments are the subject of more study and development because they are less toxic, efficacious, and cost-effective. Rapid technical improvements in peptide synthesizers and a robust pipeline of peptide therapies are the main factors driving the peptide synthesis industry in pharmaceutical and biotechnology firms.
North America is projected to hold the largest market share during the forecast period. Growth in the production of customized therapies, substantial research in the fields of genomics and proteomics, and greater investments in the creation of structure-based medicine designs have all helped the regional market. Additionally, the market will expand due to the increased awareness of the accessible peptide synthesis methods.
Asia Pacific is projected to hold the highest CAGR over the forecast period. The market is expected to develop significantly as a result of the increase in investments made by important players. Furthermore, it is expected that the region's market will grow due to rising awareness of novel peptide treatments, rising healthcare costs, the availability of more cutting-edge healthcare facilities, and significant investments made by the major players in the industry to create new peptide synthesis technologies.
Some of the key players in Peptide Synthesis market include Biotage, Genscript Biotech, Thermo Fisher Scientific, Merck KGaA, Creative Diagnostics, CEM Corporation, Bachem Holdings, PuroSynth, Syngene, Lonza, Polypeptide Group, Novo Nordisk A/S, MP Biomedicals and Evonik.
In January 2023, Merck announced an agreement to acquire the peptide synthesis company Asymchem. This acquisition will give Merck access to Asymchem's expertise in peptide synthesis and its global manufacturing network.
In December 2022, Thermo Fisher announced an agreement to acquire the peptide synthesis company Protagen. This acquisition will give Thermo Fisher access to Protagen's expertise in peptide synthesis and its global manufacturing network.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.