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基因治療學和RNAi

蛋白質表現市場規模、佔有率及成長分析（按產品/服務、系統類型、應用、最終用戶和地區分類）－2026-2033年產業預測

市場調查報告書

商品編碼

1903154

蛋白質表現市場規模、佔有率及成長分析（按產品/服務、系統類型、應用、最終用戶和地區分類）－2026-2033年產業預測

Protein Expression Market Size, Share, and Growth Analysis, By Product and Service (Reagents, Expression Vectors), By System Type, By Application, By End User, By Region - Industry Forecast 2026-2033

出版日期: 2025年12月24日 | 出版商:

SkyQuest | 英文 209 Pages | 商品交期: 3-5個工作天內

價格

簡介目錄

預計到 2024 年，蛋白質表現市場規模將達到 37.3 億美元，到 2025 年將成長至 42.2 億美元，到 2033 年將成長至 114.7 億美元，在預測期（2026-2033 年）內，預計複合年成長率為 13.3%。

受治療應用領域對重組蛋白需求不斷成長的推動，蛋白質表現市場正經歷顯著成長。生物技術的進步提高了效率和蛋白質產量，而個人化醫療的趨勢則催生了對客製化蛋白質療法的需求。在個人化醫療的廣泛應用和蛋白質工程創新的推動下，持續的研發投入正在推動市場擴張。重組蛋白的人工合成為透過客製化醫療解決方案改善患者照護創造了機會。市場參與企業正與學術機構建立策略夥伴關係，共同開發尖端技術以支持個人化治療。此外，對桿狀病毒系統以及昆蟲和哺乳動物細胞表現技術等各種蛋白質表現技術的投資不斷增加，也進一步推動了市場成長。

全球蛋白質表現市場按產品/服務、系統類型、應用、最終用戶和地區進行細分。依產品/服務分類，可分為試劑、表現載體、勝任細胞細胞、設備及服務。依系統類型分類，可分為哺乳動物細胞表現系統、原核生物表現系統、昆蟲細胞表現系統、酵母表現系統、無細胞表現系統和藻類表現系統。依應用分類，可分為治療應用、科研應用及工業應用。按最終用戶分類，可分為製藥和生物技術公司、學術研究機構、受託研究機構和合約開發與生產組織（CRO 和 CDMO）以及其他最終用戶。按地區分類，可分為北美、歐洲、亞太、中東和非洲以及拉丁美洲。

蛋白質表現市場促進因素

由於大腸桿菌這種廣泛應用的表達宿主能夠進行大規模蛋白質生產，蛋白質表現市場經歷了顯著成長。大腸桿菌的優勢在於其基因組特徵明確且定序能力強，從而能夠實現高效的克隆過程。這使其成為製藥業蛋白質生產的首選。此外，該系統的使用還能提高啟動子區域的結合強度並最佳化轉錄效率。這些因素共同推動了蛋白質表現市場需求的成長，也反映了大腸桿菌在生物製藥領域的重要角色。

蛋白質表現市場限制因素

蛋白質表現市場面臨巨大的進入門檻，主要原因是蛋白質表現試劑高成本。此外，人們對相關疾病整體缺乏了解，也導致許多公司猶豫不決，不敢進入這一領域。對於預算較為緊張的中小型企業和開發中國家的公司而言，這種情況尤其嚴峻。此外，缺乏完善的保險體係也限制了真核表達系統產品的普及，使得新興經濟體難以充分利用這個市場的潛力。

蛋白質表現市場趨勢

微流體技術的出現代表了蛋白質表現市場的一大趨勢，這得益於其在微米尺度上以無與倫比的精度操控流體的獨特能力。這種創新方法能夠精確控制極少量流體，進而增強蛋白質表現過程，使其成為最佳化蛋白質合成條件的理想選擇。微流體裝置能夠建構複雜的通道和腔室，從而支援高效的蛋白質表現環境。這使得研究人員能夠快速篩檢各種實驗條件，最終簡化工作流程，提高蛋白質研發效率，加速生物技術和醫學的進步。

哺乳動物細胞表現系統
- 中國倉鼠卵巢細胞株（CHO細胞株）
- 人類胚胎腎細胞株（Hek 293細胞株）
- 其他哺乳動物細胞株
原核表達系統
- 大腸桿菌系統
- 其他原核表達系統
昆蟲細胞表現系統
- 桿狀病毒系統
- 其他昆蟲細胞株
酵母表現系統
- 畢赤酵母系統
- 釀酒酵母系統
- 其他酵母表現系統
無細胞表現系統
基於藻類的表達系統

按應用分類的蛋白質表現市場

治療用途
研究用途
工業應用

按最終用戶分類的蛋白質表現市場

製藥和生物技術公司
學術研究機構
CRO（受託研究機構）和 CDMO（合約開發和生產組織）
其他最終用戶

蛋白質表現市場：按地區分類的市場規模：

北美洲
- 美國
- 加拿大
歐洲
- 德國
- 西班牙
- 法國
- 英國
- 義大利
- 其他歐洲地區
亞太地區
- 中國
- 印度
- 日本
- 韓國
- 亞太其他地區
拉丁美洲
- 巴西
- 其他拉丁美洲地區
中東和非洲（MEA）
- 海灣合作理事會國家
- 南非
- 其他中東和非洲地區

競爭格局

前五大公司對比
主要企業的市場定位（2025 年）
主要市場參與者所採取的策略
近期市集活動
主要企業市佔率（2025 年）

主要企業簡介

Thermo Fisher Scientific, Inc.（US）
Merck KGaA（Germany）
Genscript Biotech Corporation（China）
Agilent Technologies Inc.（US）
Takara Bio, Inc.（Japan）
Bio-Rad Laboratories, Inc.（US）
Qiagen NV（Netherlands）
Charles River Laboratories International, Inc.（US）
Danaher Corporation（US）
Sartorius AG（Germany）
Corning Incorporated（US）
Fujifilm Irvine Scientific, Inc.（Acquired by Fujifilm Holdings Corporation）（US）
Lonza Group AG（Switzerland）
Bioneer Corporation（South Korea）
Promega Corporation（US）
Oxford Expression Technologies Ltd.（UK）
Proteogenix（France）
Abeomics Inc.（US）
New England Biolabs, Inc.（US）
Promab Biotechnologies（US）
Sino Biological, Inc.（China）
Jena Bioscience（Germany）
Lifesensors, Inc.（US）
Leading Biology, Inc.（US）
Peak Proteins（UK）

簡介目錄

Product Code: SQMIG35H2291

Protein Expression Market size was valued at USD 3.73 Billion in 2024 and is poised to grow from USD 4.22 Billion in 2025 to USD 11.47 Billion by 2033, growing at a CAGR of 13.3% during the forecast period (2026-2033).

The protein expression market is witnessing significant growth, driven by the rising need for recombinant proteins in therapeutic applications. Advances in biotechnology are enhancing efficiency and protein yield, while the trend toward personalized medicine is creating demand for tailored protein therapies. Continued investment in research and development is fueling this market expansion, spurred by the popularity of personalized therapeutics and innovations in protein engineering. With the artificial synthesis of recombinant proteins, opportunities to improve patient care through customized medical solutions are emerging. Market participants are forming strategic partnerships with academic institutions to develop cutting-edge technologies that support personalized treatments. Additionally, funding is directed toward various protein expression technologies, including baculovirus systems and expression in insect and mammalian cells, further propelling market growth.

Top-down and bottom-up approaches were used to estimate and validate the size of the Protein Expression market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Protein Expression Market Segments Analysis

Global Protein Expression Market is segmented on the product & service, system type, application, end user, and region. By product and service, the market is segmented into Reagents, Expression Vectors, Competent Cells, Instruments, and Services. By system type, the market is segmented into Mammalian Cell Expression Systems, Prokaryotic Expression Systems, Insect Cell Expression Systems, Yeast Expression Systems, Cell-Free Expression Systems, and Algal-Based Expression Systems. By application, the market is segmented into Therapeutic Applications, Research Applications, and Industrial Applications. By end user, the market is segmented into Pharmaceutical & Biotechnology Companies, Academic Research Institutes, Contract Research Organizations & Contract Development and Manufacturing Organizations (CROs & CDMOs), and Other End Users. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Driver of the Protein Expression Market

The protein expression market is experiencing significant growth due to the large-scale production of proteins using E. coli bacteria, which serves as a widely adopted artificial expression host. The advantages of E. coli lie in its well-characterized genomic and sequencing capabilities, facilitating streamlined cloning processes. This makes E. coli the preferred choice within the pharmaceutical industry for protein production. Furthermore, the utilization of this system enhances the binding strength in the promoter region, thereby optimizing transcription efficiency. These factors collectively contribute to the increasing demand and expansion of the protein expression market, reflecting the pivotal role of E. coli in biopharmaceuticals.

Restraints in the Protein Expression Market

The Protein Expression market faces significant barriers that hinder the entry of new organizations, primarily due to the high costs associated with protein expression reagents. Additionally, a general lack of awareness regarding related diseases contributes to the reluctance of numerous companies to participate in this sector. This situation is particularly challenging for small enterprises and those in developing nations, where budget constraints are more pronounced. Moreover, the absence of favorable insurance frameworks further limits the adoption of eukaryotic expression system products, making it difficult for emerging economies to tap into the potential of this market.

Market Trends of the Protein Expression Market

The advent of microfluidics technology is shaping a significant trend in the Protein Expression market, driven by its ability to manipulate fluids at a microscale with unparalleled precision. This innovative approach enhances the protein expression process by enabling accurate control over minimal fluid volumes, which is ideal for optimizing conditions for protein synthesis. Microfluidic devices facilitate the creation of intricate channels and chambers that support efficient protein expression environments. As a result, researchers can conduct rapid screenings across diverse experimental conditions, ultimately streamlining workflows and improving productivity in protein research and development, thus accelerating advancements in biotechnology and pharmaceuticals.

Introduction

Objectives of the Study
Definitions
Market Scope

Research Methodology

Information Procurement
Secondary & Primary Data Sources
Market Size Estimation
Market Assumptions & Limitations

Executive Summary

Market Overview Outlook
Supply Demand Trend Analysis
Segmental Opportunity Analysis

Market Dynamics & Outlook

Market Dynamics
- Drivers
- Opportunities
- Restraints
- Challenges
Porters Analysis
- Competitive rivalry
- Threat of Substitute Products
- Bargaining Power of Buyers
- Threat of New Entrants
- Bargaining Power of Suppliers

Key Market Insights

Key Success Factor
Degree of Competition
Top Investment Pockets
Ecosystem of the Market
Pricing Analysis
Technology Analysis
Patent Analysis
Value Chain Analysis
Supply Chain Analysis
Customer & Buying Criteria Analysis
Regulatory Analysis

Protein Expression Market, By Product & Service

Market Overview
Reagents
Expression Vectors
Competent Cells
Instruments
Services

Protein Expression Market, By System Type

Market Overview
Mammalian Cell Expression Systems
- Chinese Hamster Ovary Cell Systems (Cho Cell Systems)
- Human Embryonic Kidney Cell Systems (Hek 293 Cell Systems)
- Other Mammalian Cell Systems
Prokaryotic Expression Systems
- Escherichia Coli Systems
- Other Prokaryotic Expression Systems
Insect Cell Expression Systems
- Baculovirus Systems
- Other Insect Cell Systems
Yeast Expression Systems
- Pichia Systems
- Saccharomyces Systems
- Other Yeast Expression Systems
Cell-Free Expression Systems
Algal-Based Expression Systems

Protein Expression Market, By Application

Market Overview
Therapeutic Applications
Research Applications
Industrial Applications

Protein Expression Market, By End User

Market Overview
Pharmaceutical & Biotechnology Companies
Academic Research Institutes
Contract Research Organizations & Contract Development & Manufacturing Organizations (CROS & CDMOs)
Other End Users

Protein Expression Market Market Size by Region

Market Overview
North America
- USA
- Canada
Europe
- Germany
- Spain
- France
- UK
- Italy
- Rest of Europe
Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia-Pacific
Latin America
- Brazil
- Rest of Latin America
Middle East & Africa (MEA)
- GCC Countries
- South Africa
- Rest of MEA

Competitive Landscape

Top 5 Player Comparison
Market Positioning of Key Players, 2025
Strategies Adopted by Key Market Players
Recent Activities in the Market
Key Companies Market Share (%), 2025

Key Company Profiles

Thermo Fisher Scientific, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Merck KGaA (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Genscript Biotech Corporation (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Agilent Technologies Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Takara Bio, Inc. (Japan)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bio-Rad Laboratories, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Qiagen N.V. (Netherlands)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Charles River Laboratories International, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Danaher Corporation (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Sartorius AG (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Corning Incorporated (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Fujifilm Irvine Scientific, Inc. (Acquired by Fujifilm Holdings Corporation) (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Lonza Group AG (Switzerland)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bioneer Corporation (South Korea)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Promega Corporation (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Oxford Expression Technologies Ltd. (UK)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Proteogenix (France)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Abeomics Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
New England Biolabs, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Promab Biotechnologies (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Sino Biological, Inc. (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Jena Bioscience (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Lifesensors, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Leading Biology, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Peak Proteins (UK)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments