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原位雜合反應（ISH）市場規模、佔有率和成長分析（按產品、技術、應用、最終用戶和地區分類）－2026-2033年產業預測

市場調查報告書

商品編碼

1897192

原位雜合反應（ISH）市場規模、佔有率和成長分析（按產品、技術、應用、最終用戶和地區分類）－2026-2033年產業預測

In Situ Hybridization ISH Market Size, Share, and Growth Analysis, By Product, By Technology, By Application, By End-User, By Region - Industry Forecast 2026-2033

出版日期: 2025年12月19日 | 出版商:

SkyQuest | 英文 278 Pages | 商品交期: 3-5個工作天內

價格

簡介目錄

全球原位雜合反應（ISH）市場規模預計在 2024 年達到 23.6 億美元，從 2025 年的 26.6 億美元成長到 2033 年的 68.2 億美元，在預測期（2026-2033 年）內複合年成長率為 12.5%。

由於原位雜合反應(ISH) 在定位和分析各種生物樣本中的核酸方面發揮著至關重要的作用，全球 ISH 市場正經歷顯著成長。這項先進的分子生物學技術能夠揭示目標生物體內核酸的分佈，從而支持分子診斷、基因編輯和重組 DNA 技術等重要應用。 ISH 的高靈敏度和精確定量能力使其成為免疫學、發育生物學和血液病理學等領域不可或缺的技術。其主要應用領域包括疾病預後診斷、藥物發現和生物標記評估，進一步促進了研究活動。諸如鄰近連接原位雜合反應(PLISHI) 等創新方法的出現，提高了 ISH 的性能和便利性，推動了這一充滿活力的市場領域的廣泛研發。

全球原位雜合反應（ISH）市場促進因素

全球原位雜合反應(ISH) 市場受到各人群癌症病例不斷增加的顯著影響。大量研究表明，反覆出現的基因組異常是多種癌症發展的關鍵促進因素。將包括 ISH 在內的細胞遺傳學檢測與 DNA FISH 和免疫組織化學等技術相結合，為研究人員提供了一套全面的工具包，以推進下一代診斷方法的發展。特別是，原位成像技術能夠對 RNA 水平的基因表現進行詳細分析，從而深入了解癌細胞與其周圍微環境之間的動態關係。這種日益加深的認知，加上血友病等疾病發病率的上升，預計將推動 ISH 市場顯著成長。

限制全球原位雜合反應（ISH）市場的因素

全球原位雜合反應(ISH) 市場面臨許多可能阻礙收入成長的重大挑戰。其中一個主要因素是短壽命螢光分子的固有局限性，這些分子會隨時間推移降低訊號效率，使檢測成為時間依賴性過程。此外，在核酸拷貝數低的樣本中識別特定個體也存在困難，這限制了對治療後微量殘存疾病相關的不平衡易位和低克隆細胞的檢測效果。另外，ISH 的敏感度低於免疫組織化學，雖然假陽性結果較少，但在 PCR 過程中更容易發生樣本污染。這些因素共同導致該技術在低病原體負荷疾病診斷的應用日益減少。

全球原位雜合反應（ISH）市場趨勢

由於旨在提高原位雜合反應（ISH）調查方法靈敏度的重大進步，全球ISH市場正經歷動態變化。鏈置換擴增和分子信標等創新技術拓展了ISH的應用範圍，使其能夠檢測各種生物樣本中低濃度的核酸標靶。技術的快速發展使ISH成為研究和診斷病理學中不可或缺的工具，並促進了其在臨床和檢查室環境中的廣泛應用。隨著對精準分子診斷需求的不斷成長，ISH市場持續發展，為核酸檢測的準確性和效率樹立了新的標準。

北美洲
- 美國
- 加拿大
歐洲
- 德國
- 西班牙
- 法國
- 英國
- 義大利
- 其他歐洲地區
亞太地區
- 中國
- 印度
- 日本
- 韓國
- 亞太其他地區
拉丁美洲
- 巴西
- 其他拉丁美洲地區
中東和非洲
- 海灣合作理事會國家
- 南非
- 其他中東和非洲地區

競爭資訊

前五大公司對比
主要企業的市場定位（2025 年）
主要市場參與者所採取的策略
近期市場趨勢
公司市佔率分析（2025 年）
主要企業公司簡介
- 公司詳情
- 產品系列分析
- 依業務板塊進行公司股票分析
- 2023-2025年營收年比比較

主要企業簡介

Abbott（US）
F. Hoffmann-La Roche AG（Switzerland）
Thermo Fisher Scientific Inc.（US）
Danaher（US）
Agilent Technologies, Inc.（US）
Biocare Medical, LLC（US）
Bio-Techne Corporation（US）
QIAGEN NV（Netherlands）
Merck KGaA（Germany）
PerkinElmer（US）
Enzo Biochem（US）
Bio-Rad Laboratories（US）
Abnova Corporation（Taiwan）
BioGenex Laboratories（US）
OpGen（US）
Bio SB（US）
Abcam（UK）
Zytomed Systems GmbH（Germany）
NeoGenomics Laboratories（US）
BioView（Israel）

結論與建議

簡介目錄

Product Code: SQSG35J2010

Global In Situ Hybridization ISH Market size was valued at USD 2.36 Billion in 2024 and is poised to grow from USD 2.66 Billion in 2025 to USD 6.82 Billion by 2033, growing at a CAGR of 12.5% during the forecast period (2026-2033).

The global market for In Situ Hybridization (ISH) is experiencing significant growth, driven by its critical role in localizing and analyzing nucleic acids across various biological samples. This advanced molecular biology technique supports vital applications in molecular diagnostics, gene editing, and recombinant DNA technology by revealing the distribution of nucleic acids within target organisms. High sensitivity and accurate quantification make ISH invaluable in fields like immunology, developmental biology, and hematopathology. Key applications include disease prognosis, drug discovery, and biomarker assessment, further enhancing research initiatives. Innovative methodologies, such as Proximity Ligation in Situ Hybridization, have emerged, highlighting advancements in technology that improve performance and usability while promoting extensive research and development efforts in this dynamic market landscape.

Top-down and bottom-up approaches were used to estimate and validate the size of the Global In Situ Hybridization ISH market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Global In Situ Hybridization ISH Market Segments Analysis

Global In Situ Hybridization ISH Market is segmented by Product, Technology, Application, End-User and region. Based on Product, the market is segmented into Consumables, Instruments andSoftware. Based on Technology, the market is segmented into Fluorescent In Situ Hybridization and Chromogenic in Situ Hybridization. Based on Application, the market is segmented into Cancer Diagnostics, Cytology, Infectious Disease Diagnostics, Neuroscience and Immunology. Based on End-User, the market is segmented into Hospitals and Diagnostic Laboratories and Academic & Research Institutes. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Global In Situ Hybridization ISH Market

The global In Situ Hybridization (ISH) market is significantly influenced by the rising prevalence of cancer cases across various populations. Extensive research has revealed recurrent genomic abnormalities as key factors in the initiation and progression of numerous cancers. The integration of cytogenetic assays, including ISH, along with techniques like DNA FISH and immunohistochemistry, provides researchers with a comprehensive toolkit for advancing next-generation diagnostic methodologies. Notably, in situ imaging techniques enable the detailed examination of gene expression at the RNA level, offering valuable insights into the dynamic relationship between cancer cells and their surrounding microenvironment. This growing understanding, combined with the increasing incidence of conditions such as hemophilia, positions the ISH market for substantial growth.

Restraints in the Global In Situ Hybridization ISH Market

The Global In Situ Hybridization (ISH) market faces several significant challenges that may hinder revenue growth. One key factor is the inherent limitations of short-lived fluorophore molecules, which reduce signal efficacy over time and make detection a time-sensitive process. Furthermore, the technique struggles in identifying specific individuals in samples containing low nucleic acid copies, limiting its effectiveness in detecting unbalanced translocations and low clonal cells associated with minimal residual disease post-treatment. Additionally, ISH's sensitivity is lower compared to immunohistochemistry, leading to fewer false positives and increased instances of sample contamination during PCR. These factors collectively contribute to a decline in the technique's popularity for diagnosing diseases linked to low pathogen loads.

Market Trends of the Global In Situ Hybridization ISH Market

The Global In Situ Hybridization (ISH) market is witnessing a dynamic shift driven by significant advancements aimed at enhancing the sensitivity of ISH methodologies. Innovative technologies, such as strand displacement amplification and molecular beacons, are broadening the applicability of ISH, enabling the detection of low-abundance nucleic acid targets within various biological samples. This surge in technological progress is positioning ISH as an indispensable tool in both research and diagnostic pathology, fostering increased adoption across clinical and laboratory settings. As demand for precise molecular diagnostics rises, the ISH market continues to evolve, establishing new standards for accuracy and efficiency in nucleic acid detection.

Introduction

Objectives of the Study
Scope of the Report
Definitions

Research Methodology

Information Procurement
Secondary & Primary Data Methods
Market Size Estimation
Market Assumptions & Limitations

Executive Summary

Global Market Outlook
Supply & Demand Trend Analysis
Segmental Opportunity Analysis

Market Dynamics & Outlook

Market Overview
Market Size
Market Dynamics
- Drivers & Opportunities
- Restraints & Challenges
Porters Analysis
- Competitive rivalry
- Threat of substitute
- Bargaining power of buyers
- Threat of new entrants
- Bargaining power of suppliers

Key Market Insights

Key Success Factors
Degree of Competition
Top Investment Pockets
Market Ecosystem
Market Attractiveness Index, 2025
PESTEL Analysis
Macro-Economic Indicators
Value Chain Analysis
Pricing Analysis
Technology Analysis
Regulatory Analysis
Patent Analysis
Case Studies

Global In Situ Hybridization ISH Market Size by Product & CAGR (2026-2033)

Market Overview
Consumables
- Probes
- Kits & Reagents
- Accessories
Instruments
Software

Global In Situ Hybridization ISH Market Size by Technology & CAGR (2026-2033)

Market Overview
Fluorescent In Situ Hybridization
- DNA Fluorescent in Situ Hybridization
- RNA Fluorescent in Situ Hybridization
- PNA Fluorescent in Situ Hybridization
Chromogenic in Situ Hybridization

Global In Situ Hybridization ISH Market Size by Application & CAGR (2026-2033)

Market Overview
Cancer Diagnostics
Cytology
Infectious Disease Diagnostics
Neuroscience
Immunology

Global In Situ Hybridization ISH Market Size by End-User & CAGR (2026-2033)

Market Overview
Hospitals and Diagnostic Laboratories
Academic & Research Institutes

Global In Situ Hybridization ISH Market Size & CAGR (2026-2033)

North America (Product, Technology, Application, End-User)
- US
- Canada
Europe (Product, Technology, Application, End-User)
- Germany
- Spain
- France
- UK
- Italy
- Rest of Europe
Asia Pacific (Product, Technology, Application, End-User)
- China
- India
- Japan
- South Korea
- Rest of Asia-Pacific
Latin America (Product, Technology, Application, End-User)
- Brazil
- Rest of Latin America
Middle East & Africa (Product, Technology, Application, End-User)
- GCC Countries
- South Africa
- Rest of Middle East & Africa

Competitive Intelligence

Top 5 Player Comparison
Market Positioning of Key Players, 2025
Strategies Adopted by Key Market Players
Recent Developments in the Market
Company Market Share Analysis, 2025
Company Profiles of All Key Players
- Company Details
- Product Portfolio Analysis
- Company's Segmental Share Analysis
- Revenue Y-O-Y Comparison (2023-2025)

Key Company Profiles

Abbott (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
F. Hoffmann-La Roche AG (Switzerland)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Thermo Fisher Scientific Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Danaher (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Agilent Technologies, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Biocare Medical, LLC (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bio-Techne Corporation (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
QIAGEN N.V. (Netherlands)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Merck KGaA (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
PerkinElmer (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Enzo Biochem (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bio-Rad Laboratories (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Abnova Corporation (Taiwan)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
BioGenex Laboratories (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
OpGen (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bio SB (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Abcam (UK)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Zytomed Systems GmbH (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
NeoGenomics Laboratories (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
BioView (Israel)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments