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市場調查報告書
商品編碼
1427257
ADME毒理學測試全球市場規模、佔有率、成長分析，按技術、按應用分類 - 2023-2030年產業預測Global ADME Toxicology Testing Market Size, Share, Growth Analysis, By Technology(Cell Culture, High Throughput), By Application(Systemic Toxicity, Renal Toxicity) - Industry Forecast 2023-2030 |
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2022年全球ADME毒性測試市場規模預計為74.1億美元，預測期內（2024-2031年）年複合成長率為11.5%，預計將從2023年的82.6億美元成長到2031年的197.4億美元。
ADME毒性測試市場在評估物質的藥物動力學和藥物動力學方面發揮關鍵作用，提供對其吸收率、組織分佈、代謝和排泄途徑的重要見解。其主要目的是評估藥物和化學品的潛在毒性和副作用，支持早期藥物開發、臨床前安全評估和風險管理。 ADME毒性測試市場成長的驅動力是對更安全、更有效的藥物的需求不斷成長。為了滿足嚴格的監管要求和確保病人安全的需要，製藥公司和研究人員依靠 ADME 研究來檢查潛在毒性並預測候選藥物的藥物動力學特性。然而，由於人體生理學的複雜性和個體差異，ADME毒性測試市場面臨挑戰，這可能會影響測試結果和解釋。此外，藥物研發發現和開發的快速進步使得難以跟上不斷變化的監管指南，並且需要不斷努力來保持 ADME 測試方法的準確性和可靠性。綜上所述，全球ADME毒性測試市場的重要目的是透過檢查藥物和化學品的藥物動力學和毒代動力學來評估其安全性和有效性。對更安全藥物的需求和合規性的需求推動了 ADME 毒性測試市場。儘管存在成本限制和尋找替代測試方法等挑戰，但體外和電腦測試方法的進步以及個人化醫療的潛在應用出現機會。
自上而下和自下而上的方法已用於估計和檢驗全球 ADME 毒性測試市場的規模，並估計其他各個相關子市場的規模。用於估計市場規模的調查方法包括以下細節：透過二次研究確定市場中的主要企業，並透過主要和二次研究確定市場佔有率。整個過程包括研究主要企業的年度和財務報告以及廣泛的採訪，以獲得執行長、副總裁、董事和行銷負責人等行業領導者的重要見解。所有股份比率和細分均使用二手資訊確定並使用主要資訊檢驗。本研究涵蓋的所有影響市場的參數均經過初步研究進行檢驗和分析，以獲得最終的定量和定性資料。
ADME 有毒測試全球市場細分分析
全球 ADME 毒理學測試市場根據技術、應用和區域進行細分。依技術分類，市場分為細胞培養、高通量、分子成像和體學技術。根據應用，市場分為全身性毒性、腎毒性、肝毒性、神經毒性等。依地區分類，分為北美、歐洲、亞太地區、中東、非洲、拉丁美洲。
ADME 毒理學測試的全球市場促進因素
2022年，在各種疾病的創新治療方法需求的推動下，製藥業的藥物開發力度顯著增加。對藥物研發發現和藥物開拓的日益重視在擴大 ADME 毒性測試市場方面發揮了非常重要的作用。製藥公司和研究機構在進行臨床試驗和最終推向市場之前，嚴重依賴毒理學測試來徹底評估候選藥物的安全性和有效性。
世界各地的監管機構推出了嚴格的指導方針，以確保藥品的安全性和有效性。因此，ADME 毒性測試已成為監管評估過程的重要組成部分。遵守此類監管標準並獲得核准的必要性成為2022年市場顯著成長的有力催化劑。
全球ADME毒性測試市場的限制因素
與 ADME 毒性測試相關的成本可能很高，包括各種實驗程序、專用設備和熟練勞動力。這一經濟方面將成為2022年市場成長的阻礙因素，特別是影響預算有限的中小型製藥公司。
關於動物福利的社會意識和道德考慮的提高刺激減少或取代毒理學研究中的動物測試的舉措。儘管開發和採用替代測試方法的潛力很大，但該行業在從傳統動物模型過渡到這些新方法方面面臨挑戰。相關人員的目標是在確保準確的毒理學評估和盡量減少對動物測試的依賴之間取得平衡，這一限制在2022年變得明顯。
全球 ADME 毒理學測試市場趨勢
2022年，體外和電腦測試方法的進步顯著加速。這些技術已成為傳統動物實驗的可行替代方案，為毒性評估提供了一種高效、經濟且符合倫理道德的方法。試管內測定和預測建模技術的開發和採用的進步在提高毒理學預測的準確性和可靠性方面取得了重大突破。
FDA和歐洲藥品管理局（EMA）等全球監管機構積極推動替代檢測方法的考慮和引進。其總體目標是改善動物福利並提高毒性測試的可預測性和有效性。試管內測試、器官晶片等微生理系統和計算建模技術的發展勢頭推動這一變革趨勢。公司投入資源進行研發，以創新和檢驗替代測試方法，為毒理學測試更道德和永續的發展做出貢獻。
目錄
- 執行摘要
- 調查方法
- 母市場分析
- 主要市場考察
- 技術分析
- 價格分析
- 供應鏈分析
- 價值鏈分析
- 市場生態系統
- 智慧財產權分析
- 貿易分析
- Start-Ups分析
- 原料分析
- 創新矩陣
- 研發線產品分析
- 總體經濟指標
- 主要投資分析
- 關鍵成功因素
- 競爭程度
- 市場動態及展望
- 市場動態
- 促進因素
- 機會
- 抑制因素
- 課題
- 監管形勢
- 波特的分析
- 對未來顛覆的特別見解
- 市場動態
- 全球 ADME 毒理學測試市場：依技術分類
- 市場概況
- 細胞培養
- 高通量
- 分子影像
- 體學技術
- 全球 ADME 毒理學測試市場：依應用分類
- 市場概況
- 全身毒性
- 腎毒性
- 肝毒性
- 神經毒性
- 其他
- 全球 ADME 毒性測試市場規模：依地區
- 市場概況
- 北美洲
- 美國
- 加拿大
- 歐洲
- 德國
- 西班牙
- 法國
- 英國
- 其他歐洲國家地區
- 亞太地區
- 中國
- 印度
- 日本
- 韓國
- 其他亞太地區
- 拉丁美洲
- 巴西
- 其他拉丁美洲地區
- 中東和非洲（MEA）
- 海灣合作理事會國家
- 南非
- 其他中東、非洲地區
- 競爭形勢
- 前5名企業對比
- 主要企業市場定位（2021年）
- 主要市場參與者所採取的策略
- 關鍵成功策略
- 近期市集活動
- 主要企業市場佔有率（2021年）
- 主要企業簡介
- Charles River Laboratories（US）
- Covance Inc.（US）
- Eurofins Scientific（Luxembourg）
- WuXi AppTec（China）
- Merck KGaA（Germany）
- Thermo Fisher Scientific（US）
- Cyprotex（UK）
- BioIVT（US）
- SGS SA（Switzerland）
- GE Healthcare（US）
- Promega Corporation（US）
- Absorption Systems（US）
- Catalent, Inc.（US）
- Lonza Group Ltd.（Switzerland）
- Evotec SE（Germany）
- Cyagen Biosciences（China）
- In Vitro ADMET Laboratories LLC（US）
- HD Biosciences（China）
- Sekisui XenoTech, LLC（US）
- Shanghai Medicilon Inc.（China）
Global ADME Toxicology Testing Market size was valued at USD 7.41 Billion in 2022 and is poised to grow from USD 8.26 Billion in 2023 to USD 19.74 Billion by 2031, at a CAGR of 11.5% during the forecast period (2024-2031).
The ADME toxicology testing market plays a crucial role in assessing the pharmacokinetics and toxicokinetic of substances, offering essential insights into their absorption rates, tissue distribution, metabolism, and elimination pathways. Its primary objective is to evaluate the potential toxicity and adverse effects of drugs and chemicals, thereby supporting early-stage drug development, preclinical safety assessments, and risk management. The driving force behind the growth of the ADME toxicology testing market is the escalating demand for safer and more effective drugs. In response to stringent regulatory requirements and the imperative to ensure patient safety, pharmaceutical companies and researchers rely on ADME testing to scrutinize the potential toxicity and anticipate the pharmacokinetic properties of their drug candidates. However, the ADME toxicology testing market faces challenges stemming from the intricacies of human physiology and individual variations, which can impact test outcomes and interpretations. Additionally, the rapid advancements in drug discovery and development pose difficulties in keeping pace with evolving regulatory guidelines, requiring constant efforts to uphold the accuracy and reliability of ADME testing methods. In essence, the global ADME toxicology testing market serves the crucial purpose of evaluating the safety and efficacy of drugs and chemicals by examining their pharmacokinetics and toxicokinetic. It is primarily fuelled by the demand for safer pharmaceuticals and the imperative of regulatory compliance. Despite challenges such as cost constraints and the exploration of alternative testing methods, opportunities emerge from advancements in in vitro and in silico testing approaches, along with the potential applications in personalized medicine.
Top-down and bottom-up approaches were used to estimate and validate the size of the Global ADME Toxicology Testing Market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.
Global ADME Toxicology Testing Market Segmental Analysis
The global ADME toxicology testing market is segmented on the basis of technology, application, and region. By Technology, the market is segmented into Cell Culture, High Throughput, Molecular Imaging, and OMICS Technology. By Application, the market is segmented into Systemic Toxicity, Renal Toxicity, Hepatotoxicity, Neurotoxicity, and Others. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.
Drivers of the Global ADME Toxicology Testing Market
In 2022, the pharmaceutical industry witnessed a significant upswing in drug development initiatives, spurred by the demand for innovative therapies across various diseases. This intensified emphasis on drug discovery and development played a pivotal role in the expansion of the ADME toxicology testing market. Pharmaceutical companies and research institutions heavily relied on toxicology testing to meticulously evaluate the safety and effectiveness of their drug candidates before advancing to clinical trials and eventual market introduction.
Global regulatory authorities implemented stringent guidelines to ensure the robust assessment of safety and efficacy in pharmaceutical products. Consequently, ADME toxicology testing emerged as an indispensable element in the regulatory evaluation process. The imperative to adhere to these regulatory standards and secure approvals acted as a compelling catalyst for the substantial growth observed in the market throughout 2022.
Restraints in the Global ADME Toxicology Testing Market
The expenses associated with ADME toxicology testing can be substantial, encompassing various experimental procedures, specialized equipment, and a skilled workforce. This financial aspect acted as a hindrance to market growth in 2022, particularly impacting small and medium-sized pharmaceutical companies operating within constrained budgets.
Growing societal awareness and ethical considerations regarding animal welfare have stimulated initiatives to decrease or substitute animal testing in toxicology studies. While the potential of developing and adopting alternative testing methods is promising, the industry faced challenges in transitioning from traditional animal models to these newer approaches. This constraint was evident in 2022, as stakeholders aimed to strike a balance between ensuring precise toxicological assessments and minimizing reliance on animal experimentation.
Market Trends of the Global ADME Toxicology Testing Market
In 2022, there was a notable acceleration in the advancement of in vitro and in silico testing methods. These technologies emerged as viable alternatives to traditional animal testing, offering efficient, cost-effective, and ethically sound approaches to toxicology evaluation. The progress in developing and adopting in vitro assays and predictive modelling techniques marked a significant leap forward, enhancing the accuracy and reliability of toxicology predictions.
Global regulatory bodies, such as the FDA and the European Medicines Agency (EMA), actively promoted the exploration and incorporation of alternative testing methods. The overarching goal is to improve animal welfare and enhance the predictability and relevance of toxicity testing. The momentum in in vitro testing, micro physiological systems like organ-on-a-chip, and computational modelling techniques is steering this transformative trend. Companies are dedicating resources to research and development endeavours to innovate and validate alternative testing approaches, thereby contributing to the evolution of a more ethical and sustainable landscape for toxicology testing.
Table of Contents
- Executive Summary
- Market Overview
- Wheel of Fortune
- Research Methodology
- Information Procurement
- Secondary & Primary Data Sources
- Market Size Estimation
- Market Assumptions & Limitations
- Parent Market Analysis
- Market Overview
- Market Size
- Market Dynamics
- Drivers
- Opportunities
- Restraints
- Challenges
- Key Market Insights
- Technology Analysis
- Pricing Analysis
- Supply Chain Analysis
- Value Chain Analysis
- Ecosystem of the Market
- IP Analysis
- Trade Analysis
- Startup Analysis
- Raw Material Analysis
- Innovation Matrix
- Pipeline Product Analysis
- Macroeconomic Indicators
- Top Investment Analysis
- Key Success Factor
- Degree of Competition
- Market Dynamics & Outlook
- Market Dynamics
- Drivers
- Opportunities
- Restraints
- Challenges
- Regulatory Landscape
- Porters Analysis
- Competitive rivalry
- Threat of Substitute Products
- Bargaining Power of Buyers
- Threat of New Entrants
- Bargaining Power of Suppliers
- Skyquest Special Insights on Future Disruptions
- Political Impact
- Economic Impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
- Market Dynamics
- Global ADME Toxicology Testing Market by Technology
- Market Overview
- Cell Culture
- High Throughput
- Molecular Imaging
- and OMICS Technology
- Global ADME Toxicology Testing Market by Application
- Market Overview
- Systemic Toxicity
- Renal Toxicity
- Hepatotoxicity
- Neurotoxicity
- and Others
- Global ADME Toxicology Testing Market Size by Region
- Market Overview
- North America
- USA
- Canada
- Europe
- Germany
- Spain
- France
- UK
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia-Pacific
- Latin America
- Brazil
- Rest of Latin America
- Middle East & Africa (MEA)
- GCC Countries
- South Africa
- Rest of MEA
- Competitive Landscape
- Top 5 Player Comparison
- Market Positioning of Key Players, 2021
- Strategies Adopted by Key Market Players
- Top Winning Strategies
- By Development
- By Company
- By Year
- Recent Activities in the Market
- Key Companies Market Share (%), 2021
- Key Company Profiles
- Charles River Laboratories (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Covance Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Eurofins Scientific (Luxembourg)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- WuXi AppTec (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Merck KGaA (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Thermo Fisher Scientific (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Cyprotex (UK)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- BioIVT (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- SGS SA (Switzerland)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- GE Healthcare (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Promega Corporation (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Absorption Systems (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Catalent, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Lonza Group Ltd. (Switzerland)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Evotec SE (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Cyagen Biosciences (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- In Vitro ADMET Laboratories LLC (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- HD Biosciences (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Sekisui XenoTech, LLC (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Shanghai Medicilon Inc. (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
- Charles River Laboratories (US)
