市場調查報告書
商品編碼
1173206
特應性皮炎治療藥物全球市場規模,份額和行業趨勢分析報告:按給藥途徑,類別(生物製劑,神經鈣蛋白抑製劑,皮質類固醇,PDE4抑製劑)區域展望和預測2022-2028Global Atopic Dermatitis Drugs Market Size, Share & Industry Trends Analysis Report By Route of Administration, By Class (Biologics, Calcineurin Inhibitors, Corticosteroids, PDE4 Inhibitors), By Regional Outlook and Forecast, 2022 - 2028 |
到 2028 年,特應性皮炎療法的全球市場規模預計將達到 220 億美元,預測期內復合年增長率為 9.2%。
特應性皮炎可在任何年齡發病,但通常首先出現在兒童時期,其嚴重程度隨時間而變化。 在 1 歲以下的兒童中,身體的許多部位都會受到影響。 隨著孩子年齡的增長,內側膝蓋和肘部是最常受影響的區域。 在成年人中,它最常見於手腳。
抓撓患處會加重病情,抓撓者更容易發生皮膚感染。 特應性皮炎通常會導致哮喘和花粉熱。 治療包括避免加重疾病的事物、定期洗澡和使用保濕霜、出現症狀時使用類固醇霜以及減少瘙癢的藥物。
羊毛衣物、肥皂、香水、灰塵、氯氣和香煙煙霧是經常加重症狀的一些因素。 光療可能對某些人有幫助。 當其他治療無效時,可使用類固醇藥片和基於鈣調神經磷酸□抑製劑的洗劑。 如果有細菌感染,應給予抗生素(口服或外用)。 只有在檢測到食物過敏時才需要飲食治療。
COVID-19 影響分析
冠狀病毒正在全球範圍內給人們的生活帶來問題,擾亂從社交互動到醫療保健再到我們看待外部世界的方式等方方面面。 由於大流行,所有行業的利潤和產量都在下降。 然而,由於患者就診不規律,特應性皮炎治療市場預計將受到嚴重影響。 即使在這種情況下,遠程皮膚病學仍在繼續發展,因為絕大多數患者無需看醫生就能接受常規和後續護理。
市場增長因素
對生物製劑的需求不斷增長
皮膚病的治療,尤其是特應性皮炎,已經通過在皮膚病學中使用生物製劑而發生了轉變。 生物製劑能夠很好地應對特應性皮炎並改善整體生活質量。 因此,現在對特應性皮炎的生物治療的需求不斷增長。 這種模式可能會在未來幾年繼續下去。 目前只有一種生物製劑被批准用於治療特應性皮炎。 許多產品目前正在進行二期臨床試驗,並可能在不久的將來獲得批准。
特應性皮炎患病率上升
預計推動特應性皮炎藥物市場的主要因素是全球特應性皮炎患者數量的增加。 許多人患有特應性皮炎,預計未來幾年這一數字還會增加。 地理條件、氣候條件、社會經濟地位、生活方式、年齡、性別、遺傳和個人行為都會影響世界範圍內特應性皮炎的患病率。 特應性皮炎必須與日常過敏有關。
市場製約因素
外用類固醇的副作用
少於 4 週的局部類固醇治療通常沒有風險或問題。 長期使用局部類固醇和頻繁短劑量使用高刺激性類固醇會引起問題。 一個主要問題是長期使用強效類固醇。 溫和的局部類固醇幾乎沒有副作用。 外用類固醇具有局部和全身副作用。 系統性是影響整個個體的問題,局部性是影響皮膚特定區域的問題。
班級展望
根據類別,特應性皮炎治療市場分為皮質類固醇、神經鈣蛋白抑製劑、PDE4 抑製劑、生物製劑等。 到 2021 年,皮質類固醇部分在特應性皮炎治療市場中佔有重要的收入份額。 可的松、氫化可的松和潑尼松等皮質類固醇藥物可以成功治療炎症性腸病、皮疹和哮喘等許多病症。
管理路線展望
根據給藥途徑,特應性皮炎藥物市場分為外用劑、注射劑和口服劑。 注射劑將在 2021 年的特應性皮炎藥物市場中佔據最大的收入份額。 這是由於像 dupilumab 這樣的注射劑越來越受歡迎。 Tofacitinib 和 ruxolitinib 是其他正在臨床試驗中研究的可注射生物製劑。 在不久的將來,生物製劑有望改變 AD 治療格局。
區域展望
按地區分析了北美、歐洲、亞太地區和 LAMEA 的特應性皮炎治療市場。 2021 年,北美地區將以最高的收入份額引領特應性皮炎治療市場。 成熟的研發基礎設施和友好的報銷規則是該地區持續佔據主導地位的兩個關鍵因素。 此外,隨著該領域研究的快速發展,監管和報銷環境也在不斷變化。
收購是市場進入者採取的主要策略。 根據 Cardinal Matrix 中的分析,Pfizer和Novartis AG在特應性皮炎藥物市場處於領先地位。 AbbVie, Inc.、Sanofi SA 和 Regeneron Pharmaceuticals Inc. 等公司是特應性皮炎治療市場的一些領先創新者。
The Global Atopic Dermatitis Drugs Market size is expected to reach $22 billion by 2028, rising at a market growth of 9.2% CAGR during the forecast period.
Eczema, commonly referred to as atopic dermatitis, is a skin ailment that affects the skin and results in itching, dryness, and inflammation. The illness has a potential for chronicity and occasionally flares up and spreads. Drugs for atopic dermatitis, such as atopic eczema steroids, are utilized to treat eczema, lessen itching, and treat other atopic dermatitis-related disorders.
Atopic dermatitis patients run the risk of acquiring asthma, hay fever, and food allergies. Regular moisturizing and other skin care practices help reduce itching and stop future outbreaks. Medicated lotions or ointments may also be used during treatment. It causes skin that is scratchy, red, swollen, and cracked. The damaged sites may leak a clear fluid that thickens over time.
Although the disorder can strike at any age, it usually first manifests in childhood and varies in severity throughout time. Much of the body may be impacted in youngsters under the age of one year. The areas on the inside of the knees and elbows are most frequently affected as kids age. Adults are more frequently afflicted in the hands and feet.
Scratching the affected regions makes the symptoms worse, and individuals who are scratching have a higher chance of developing skin infections. Atopic dermatitis frequently leads to the development of asthma or hay fever. Avoiding things that aggravate the illness, regular bathing followed by the use of moisturizing cream, using steroid creams when flare-ups happen, and drugs to relieve itching are all part of the treatment.
Wool garments, soaps, fragrances, dust, chlorine, and cigarette smoke are a few things that frequently aggravate it. Some people may benefit from phototherapy. If other treatments are ineffective, steroid tablets or lotions based on calcineurin inhibitors may occasionally be employed. If a bacterial infection manifests, antibiotics (by mouth or topically) could be required. Only if food allergies are detected are dietary modifications required.
COVID-19 Impact Analysis
The coronavirus is still creating trouble in people's lives on a worldwide scale, disrupting everything from social interactions to how they seek medical care and see the outside world. Every industry has experienced a profit or output decrease as a result of the pandemic epidemic. However, the market for treating atopic dermatitis has anticipated a substantial impact because of the irregularity of hospital visits by patients. Teledermatology has grown during the crisis when the majority of patients continue to receive generalized care and/or additional consultative therapies without seeing a doctor in person.
Market Growth Factors
Growing Demand For Biologics
The treatment of dermatological disorders, particularly atopic dermatitis, has changed as a result of the use of biologic drugs in dermatology. Biologics have demonstrated a good response to atopic dermatitis, improving the overall quality of life. As a result, there is now a greater demand for biologic treatments for atopic dermatitis. In the upcoming several years, this pattern is probably going to continue. For the time being, only one biologic product has been authorized for the treatment of atopic dermatitis. Many more are currently through phase II clinical studies and will probably be approved soon.
Rising Prevalence Of Atopic Dermatitis
The increasing prevalence of atopic dermatitis medications around the world is anticipated to be the main factor driving the market for atopic dermatitis medications. A large number of people suffer with atopic dermatitis which is expected to rise even more in upcoming years. Geographical location, climatic circumstances, socioeconomic level, lifestyle, age, gender, inheritance, and individual behaviors all have an impact on the prevalence of dermatological problems around the world. An individual with atopic dermatitis must deal with allergies on a daily basis.
Market Restraining Factors
Side Effects Of Topical Steroids
Topical steroid treatments lasting fewer than four weeks are often risk-free and trouble-free. Long-term topical steroid use or frequent repetition of short doses of harsher steroids may cause issues. The primary issue is the prolonged usage of potent steroids. Mild topical steroids rarely have side effects. Topical steroids may have local or systemic side effects. Systemic refers to an issue that affects the entire individual, whereas local refers to that particular area of skin.
Class Outlook
Based on class, the atopic dermatitis drugs market is segmented into corticosteroids, calcineurin inhibitors, PDE4 inhibitors, biologics and others. In 2021, the corticosteroids segment acquired a substantial revenue share in the atopic dermatitis drugs market. Many conditions, such as inflammatory bowel disease, rashes, and asthma, can be successfully treated with corticosteroid medications, such as cortisone, hydrocortisone, and prednisone.
Route Of Administration Outlook
On the basis of route of administration, the atopic dermatitis drugs market is fragmented into topical, injectable and oral. In 2021, the injectable segment held the largest revenue share in the atopic dermatitis drugs market. This is due to the rising popularity of injectable drugs like Dupilumab. Tofacitinib and ruxolitinib are other injectable biologics being studied in clinical trials. In the near future, biologics are anticipated to alter the therapy landscape for AD.
Regional Outlook
Region wise, the atopic dermatitis drugs market is analyzed across North America, Europe, Asia Pacific and LAMEA. In 2021, the North America region led the atopic dermatitis drugs market by generating the highest revenue share. The availability of a well-established R&D infrastructure and kind reimbursement rules are two major factors contributing to the region's sustained dominance. Additionally, the regulatory and reimbursement environment is constantly changing to keep up with the rapid advancement of research in this field.
The major strategies followed by the market participants are Acquisitions. Based on the Analysis presented in the Cardinal matrix; Pfizer, Inc. and Novartis AG are the forerunners in the Atopic Dermatitis Drugs Market. Companies such as AbbVie, Inc., Sanofi SA, Regeneron Pharmaceuticals Inc. are some of the key innovators in Atopic Dermatitis Drugs Market.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Pfizer Inc., Sanofi SA, AbbVie Inc., Galderma S.A., Eli Lilly and Company, Leo Pharma A/S, Regeneron Pharmaceuticals Inc., Otsuka Pharmaceutical Co. Ltd., Novartis AG, and Incyte Corporation.
Recent Strategies Deployed in Atopic Dermatitis Drugs Market
Mergers and Acquisitions:
Oct-2022: Incyte completed the acquisition of Villaris Therapeutics, an asset-centric biopharmaceutical company. This acquisition would complement Incyte's current portfolio, providing Incyte the opportunity to improve treatment options for people with vitiligo, that leverage the expertise established in the dermatology space.
Jun-2022: Pfizer took over ReViral, a privately held, clinical-stage Biopharmaceutical Company. This acquisition further demonstrates Pfizer's commitment to advancing pioneering science both through its in-house expertise and work with leading, innovative companies - with the aim to deliver breakthroughs to patients suffering from severe infectious diseases.
Mar-2022: Pfizer completed the acquisition of Arena Pharmaceuticals, an American biopharmaceutical company. Through this acquisition, Pfizer would add the impressive experience and pipeline of Arena Pharmaceuticals to Pfizer's Inflammation & Immunology therapeutic area, helping the company further its purpose of developing breakthroughs to change the lives of those with immuno-inflammatory diseases.
Jan-2022: Galderma took over ALASTIN Skincare, a specialty aesthetics company. This acquisition aimed at enhancing Galderma's integrated dermatology platform with a comprehensive collection of scientifically-approved products for daily skincare regimens and peri-procedural use. Also, the acquisition would underscore Galderma's commitment to being the partner of choice for aesthetic professionals.
Dec-2021: AbbVie took over Soliton, a medical device company. The acquisition would complement Allergan Aesthetics' portfolio of non-invasive body contouring treatments to include a proven treatment for the appearance of cellulite.
Nov-2021: Sanofi completed the acquisition of Translate Bio, a biotechnology company that specializes in biotechnology, RNA therapeutics, and rare diseases. The acquisition support Sanofi's mRNA Center of Excellence, which plans to explore the potential of enhanced mRNA vaccines & other key areas that includes immunology, oncology, and rare diseases.
Nov-2021: Sanofi took over Kadmon Holdings, which operates as a biopharmaceutical company. This acquisition would strengthen the expansion & growth of the general medicines portfolio.
Jul-2019: LEO Pharma completed the acquisition of Bayer. LEO Pharma advances significantly towards its goal of helping 125 million patients by 2025. With this acquisition, the LEO considerably improve its size in key markets like Austria, Brazil, and South Africa - underlining its ambition to become a global leader in medical dermatology.
Approvals and Trials:
Oct-2022: LEO Pharma got European approval for Adtralza, a drug to treat moderate-to-severe AD in adolescents. The approval would address LEO's relentless commitment to bringing the latest treatment options for those living with atopic dermatitis. This approval enables LEO to address the unmet needs of a broader patient population as it looks forwards to work with key stakeholders across the Europe region.
Jun-2022: Sanofi got FDA approval for Dupixent, a biologic medicine approved to treat moderate-to-severe atopic dermatitis from infancy to adulthood. The approval would enable the availability of Dupixent for young people with the disease.
Jan-2022: Pfizer got FDA approval for CIBINQO, an oral, once-daily, Janus kinase 1 (JAK1) inhibitor. CIBINQO would offer the treatment of adults living with refractory, moderate-to-severe atopic dermatitis (AD) whose disease is not adequately controlled with other systemic drug products. CIBINQO would provide an important latest oral option that would help those who have yet to find relief.
Jan-2022: AbbVie got FDA approval for RINVOQ, a once-daily oral option that can significantly enhance the debilitating itch & skin symptoms of atopic dermatitis. Through this acquisition, AbbVie would continue its efforts to enhance care in this disease state & other chronic, immune-mediated conditions.
Dec-2021: Leo Pharma got FDA approval for Adbry, an eczema drug. The injected antibody drug would address adults and older who don't get proper relief from topical prescription therapies. Adbry would signify important progress in LEO's aim of enhancing the standard of care in medical dermatology.
Sep-2021: Otsuka got FDA approval for Moizerto Ointment, a treatment for atopic dermatitis. Otsuka expects that Moizerto Ointment would serve as the latest treatment option for people having atopic dermatitis in Japan.
Sep-2021: Incyte got FDA approval for Opzelura, a topical JAK inhibitor to treat AD. With this approval, the company looks forward to bringing Opzelura to the patient community and also continuing to explore its potential in other skin diseases.
Market Segments covered in the Report:
By Route of Administration
By Class
By Geography
Companies Profiled
Unique Offerings from KBV Research
List of Figures