市場調查報告書
商品編碼
1467955
RNA 治療市場:按技術、適應症和最終用戶分類 - 2024-2030 年全球預測RNA Therapy Market by Technology (Enabled Technologies, Enabling Technologies), Indication (Cancer, Cardiovascular, Genetic Disorders), End User - Global Forecast 2024-2030 |
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預計2023年RNA治療市場規模為21.8億美元,預計2024年將達26億美元,2030年將達89.8億美元,複合年成長率為22.38%。
RNA 療法涉及利用核糖核酸 (RNA) 分子靶向特定基因序列或細胞機制的治療方法的開發和商業化。這些治療方法透過靶向 RNA 分子來取代缺陷基因、抑制有害基因表現或調節細胞功能來治療多種疾病和病症。對生物技術新興企業的投資增加、學術界和工業界參與者之間不斷加強的合作以及針對未滿足的醫療需求不斷擴大的潛在治療標靶組合正在推動對 RNA 療法的需求。孤兒藥認定和加速核准等有利的監管政策加速了多種基於 RNA 的治療方法的臨床開發。與體內 RNA 分子的不穩定性和快速分解相關的遞送挑戰正在阻礙市場成長。製藥公司在利用最尖端科技對治療選擇有限的罕見疾病進行新型 RNA 療法方面不斷取得進展,預計將為市場成長創造機會。
主要市場統計 | |
---|---|
基準年[2023] | 21.8億美元 |
預測年份 [2024] | 26億美元 |
預測年份 [2030] | 89.8億美元 |
複合年成長率(%) | 22.38% |
技術:對可用技術的需求不斷成長將推動 RNA 療法的進步。
透過提供精確操縱 RNA 分子並將其遞送至目標細胞所需的工具,可用技術將加速 RNA 治療的進步。該技術透過將小干擾 RNA (siRNA) 引入細胞來定序特定基因。實行技術透過提供改進的設計、合成、修飾和傳遞 RNA 分子的方法來促進實行技術的開發和應用。 RNA干擾(RNAi)、反義寡核苷酸 (ASO) 和信使核糖核酸 (mRNA) 療法等技術提供了根據目標疾病機制調節基因表現的不同方法。
適應症 RNA 療法在遺傳和癌症疾病方面的廣泛應用。
RNA療法透過針對特定的癌基因和抑癌基因,在癌症治療中極為重要。這些治療方法有助於控制癌細胞中經常被破壞的基因表現。基於需求的癌症 RNA 治療偏好包括根據患者基因組成量身定做的個人化治療。 RNA療法透過調節疾病相關基因的表達,在治療心臟衰竭和高血壓等心血管疾病方面具有潛在的應用。患有嚴重或罕見心血管疾病的患者可能會受益於這種標靶治療,因為它們比傳統治療方法副作用更少且更有效。 RNA療法可用於治療單一基因突變或缺陷引起的遺傳性疾病。這種基於需求的優先重點是針對患有罕見且危及生命的遺傳性疾病且治療選擇有限的患者。 RNA 療法可以透過調節宿主的免疫反應或直接針對病原體來對抗病毒和細菌感染,例如 COVID-19、B型肝炎和結核病。優先考慮抗藥性感染疾病患者和感染疾病期間需要快速反應的患者。 RNA療法透過針對參與腎功能和纖維化的特定基因,為多囊性腎病變和糖尿病腎臟病等慢性腎臟病提供了新的治療選擇。 RNA療法有潛力透過調節參與葡萄糖和脂質代謝的關鍵基因來治療肥胖、非酒精性脂肪性肝炎(NASH)和第2型糖尿病等代謝性疾病。除了癌症疫苗之外,RNA療法還用於透過編碼患者特異性腫瘤抗原來開發針對各種腫瘤類型的個人化免疫療法。這種基於需求的偏好針對的是對標準治療方法反應不佳的侵襲性或轉移性癌症患者。 RNA療法可以透過將受影響基因的功能副本直接傳遞到視網膜細胞中來幫助治療由基因突變引起的視網膜疾病,例如萊伯氏先天性黑朦症和老齡化黃斑部病變。
最終用戶:學術研究越來越重視推動診斷和藥物開發的新發現。
學術研究主要使用RNA療法來了解基因功能和調控。研究人員採用了多種 RNA 治療方法,包括小干擾 RNA (siRNA)、反義寡核苷酸 (ASO)、微型RNA(miRNA) 和傳訊RNA(mRNA) 療法。基於 RNA 的診斷著重於透過標靶序列測定和基因表現檢測疾病特異性生物標記。與傳統的基於 DNA 的方法相比,這些診斷方法提高了靈敏度。 RNA 標靶藥物的發現和開發涉及識別新的治療標靶、設計選擇性 RNA 結合小分子或寡核苷酸以及開發創新的遞送系統來克服細胞損傷。
區域洞察
美洲 RNA 治療市場得到發達的醫療保健部門和政府支持計劃的支持,美國和加拿大的尖端 RNA 療法已實現顯著商業化,南美國家的製藥業正在發展。美洲各國政府鼓勵技術進步和研究工作,以為人民提供更好的醫療保健系統,並為整體經濟成長和公共福祉做出貢獻。日本、印度、中國和韓國等亞太地區新興經濟體和已開發經濟體的政府正在鼓勵 RNA 療法的研究和開發。隨著新設備和技術迅速商業化並被接受,RNA 療法在歐洲已廣泛採用,醫療保健專業人員也能使用 RNA 療法。同時,歐洲人口老化正在迅速加劇,多種感染疾病和慢性病的適應症預計將增加。根據人口研究所(PRB)的數據,俄羅斯、德國、義大利、法國、英國、西班牙、土耳其、烏克蘭、波蘭、奈及利亞和伊朗是65歲及以上人口比例最高的國家。由於歐洲人口老化和殘疾徵兆像日益增多,需要有效的 RNA 療法。
FPNV定位矩陣
FPNV定位矩陣對於評估RNA治療市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可對 RNA 治療市場供應商的現狀進行深入而詳細的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。這種詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4.競爭評估與資訊:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況、製造能力等進行全面評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1.RNA治療市場的市場規模與預測是多少?
2.RNA治療市場預測期內需要考慮投資的產品、細分市場、應用和領域有哪些?
3.RNA治療市場的技術趨勢和法規結構是什麼?
4.RNA治療市場主要廠商的市場佔有率為何?
5.進入RNA治療市場的合適型態和策略手段是什麼?
[187 Pages Report] The RNA Therapy Market size was estimated at USD 2.18 billion in 2023 and expected to reach USD 2.60 billion in 2024, at a CAGR 22.38% to reach USD 8.98 billion by 2030.
RNA therapy includes developing and commercializing therapeutic approaches that utilize ribonucleic acid (RNA) molecules to target specific genetic sequences and cellular mechanisms. These therapies treat various diseases and conditions by replacing faulty genes, silencing harmful gene expressions, or modulating cellular functions by targeting RNA molecules. Increasing investments in biotechnology startups, growing collaborations between academia and industry players, and an expanding portfolio of potential therapeutic targets for unmet medical needs drive the need for RNA therapies. Favorable regulatory policies for orphan drug designation and fast-track approvals have accelerated the clinical development of several RNA-based therapies. Delivery challenges associated with instability and rapid degradation of RNA molecules in vivo hampers market growth. Ongoing advancements by pharmaceutical companies to leverage cutting-edge technologies into novel RNA treatments for rare diseases with limited treatment options are expected to create opportunities for market growth.
KEY MARKET STATISTICS | |
---|---|
Base Year [2023] | USD 2.18 billion |
Estimated Year [2024] | USD 2.60 billion |
Forecast Year [2030] | USD 8.98 billion |
CAGR (%) | 22.38% |
Technology: Growing demand for enabled technologies to elevate the advancements in RNA therapies.
Enabled technology drives the advancement in RNA therapy as it provides the tools necessary for precisely manipulating and delivering RNA molecules to target cells. This technology silences specific genes by introducing small interfering RNAs (siRNAs) into cells. Enabling technologies facilitate the development and application of enabled technologies by providing improved RNA molecule design, synthesis, modification, and delivery methods. Enabled technologies such as RNA interference (RNAi), Antisense Oligonucleotides (ASOs), and messenger Ribonucleic Acid (mRNA) therapeutics offer different approaches to modulating gene expression depending on the targeted disease mechanism.
Indication: Widespread applications of RNA therapy in genetic and cancer diseases.
RNA therapy is crucial in cancer treatment by targeting specific oncogenes or tumor suppressor genes. These therapies help to regulate gene expression, which is often disrupted in cancerous cells. Need-based preference for RNA therapy in cancer includes personalized treatments tailored to the patient's genetic makeup. RNA therapy has potential applications for treating cardiovascular diseases such as heart failure and hypertension by modulating the expression of disease-related genes. Patients with severe or rare cardiovascular conditions may benefit from these targeted therapies as they offer fewer side effects and better efficacy compared to conventional treatments. RNA therapy can be used to treat genetic disorders caused by mutations or deficiencies in single genes. This need-based preference focuses on patients with rare, life-threatening genetic diseases with limited treatment options. By modulating host immune responses or directly targeting pathogens, RNA therapy can help combat viral and bacterial infections such as COVID-19, hepatitis B, and tuberculosis. Preference exists for patients suffering from drug-resistant infections or requiring rapid response treatments during outbreaks. RNA therapy provides new treatment options for chronic kidney diseases such as polycystic kidney disease and diabetic nephropathy by targeting specific genes involved in renal function and fibrosis. RNA therapy has the potential to treat metabolic disorders, including obesity, non-alcoholic steatohepatitis (NASH), and type 2 diabetes by regulating key genes involved in glucose and lipid metabolism. In addition to cancer vaccines, RNA therapy is used to develop personalized immunotherapies for various tumor types by encoding patient-specific tumor antigens. This need-based preference targets patients with aggressive or metastatic cancers that do not respond well to standard treatments. RNA therapy helps to treat retinal diseases caused by genetic mutations, such as Leber's congenital amaurosis and age-related macular degeneration, by delivering functional copies of the affected genes directly into retinal cells.
End User: Growing emphasis on academic research focusing on novel discoveries that propel diagnostics and drug development.
In academic research, RNA therapy is primarily utilized for understanding gene function and regulation. Researchers employ various RNA therapeutic approaches such as small interfering RNAs (siRNAs), antisense oligonucleotides (ASOs), microRNAs (miRNAs), and messenger RNA (mRNA) therapeutics. RNA-based diagnostics focuses on detecting disease-specific biomarkers through targeted sequencing or gene expression profiling. These diagnostic methods offer increased sensitivity compared to traditional DNA-based techniques. RNA-targeted drug discovery and development involve identifying novel therapeutic targets, designing selective RNA-binding small molecules or oligonucleotides, and developing innovative delivery systems to overcome cellular barriers.
Regional Insights
The RNA therapy market in the Americas is supported by a developed healthcare sector and supportive government programs, resulting in considerable commercialization of cutting-edge RNA therapies in the United States and Canada and the evolving pharmaceutical industry in South American countries. The governments in the Americas encourage technological advancements and research activities to provide a better healthcare system to people that contribute to overall economic growth and public welfare. The governments in the Asia-Pacific region's emerging and developed economies, such as Japan, India, China, and South Korea, encourage research and development of RNA therapies. Europe has significantly adopted RNA therapies owing to the rapid commercialization and acceptability of new devices and technologies, enabling healthcare professionals to use RNA therapies. On the other hand, the surging geriatric population in Europe is expected to increase the indication of several infectious and chronic disorders. As per the Population Reference Bureau (PRB), Russia, Germany, Italy, France, the UK, Spain, Turkey, Ukraine, Poland, Nigeria, and Iran are some countries that have a significant percentage of the population aged over 65 years. The rising indication of Europe's aging population and disorders necessitates efficient RNA therapies.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the RNA Therapy Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the RNA Therapy Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the RNA Therapy Market, highlighting leading vendors and their innovative profiles. These include Alnylam Pharmaceuticals, Inc., Arbutus Biopharma Corporation, Arcturus Therapeutics Holdings Inc., Arrowhead Pharmaceuticals, Inc., AstraZeneca PLC, Benitec Biopharma Limited, Biogen Inc., BioNTech SE, Cartesian Therapeutics, Inc., Cenix BioScience GmbH, Deep Genomics, Eli Lilly and Company, F. Hoffmann-La Roche AG, GSK PLC, Ionis Pharmaceuticals, Inc., Laronde, MiNA Therapeutics Limited, Moderna, Inc., NeuBase Therapeutics, Inc., Nordic Nanovector ASA, Novartis AG, Novo Nordisk A/S, Nutcracker Therapeutics, Inc., ProQR Therapeutics N.V., Sanofi S.A., Silence Therapeutics PLC, Sirnaomics, Inc., and Triplet Therapeutics, Inc..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the RNA Therapy Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the RNA Therapy Market?
3. What are the technology trends and regulatory frameworks in the RNA Therapy Market?
4. What is the market share of the leading vendors in the RNA Therapy Market?
5. Which modes and strategic moves are suitable for entering the RNA Therapy Market?