市場調查報告書
商品編碼
1470849
體外毒理學測試市場:按技術、方法、應用、最終用戶產業分類 - 2024-2030 年全球預測In-Vitro Toxicology Testing Market by Technology (Cell Culture Technology, High Throughput Technology, Molecular Imaging), Method (Biochemical Assay, Cellular Assay, Ex-vivo), Application, End-User Industry - Global Forecast 2024-2030 |
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體外毒理學測試市場規模預計2023年為122.1億美元,預計2024年將達到134.9億美元,2030年將達到252.1億美元,複合年成長率為10.90%。
體外毒性測試市場採用細胞培養和器官培養來評估化學物質、藥品和食品等物質的毒性。這種創新方法用於製藥、化妝品和食品行業,在準確性、再現性和速度方面具有顯著的優勢。由於測試方法的進步、對動物測試態度的增強以及對具有成本效益的安全措施的需求不斷成長,該市場正在蓬勃發展。一個潛在的成長領域在於藥物和治療方法開發中使用體外模型,這些模型密切模仿人類生物化學並最大限度地減少臨床試驗失敗的發生率。此外,基因組學和蛋白質組學的進步提供了巨大的成長機會。然而,這個市場面臨著諸如解釋測試資料的複雜性、體內條件再現的困難以及監管複雜性等挑戰,所有這些都導致了高昂的營運成本。未來的業務成長取決於重點研究,以提高體外測試系統的預測準確性,同時降低成本。與監管機構就測試認可和核准進行合作計算生物學和基因組學的進步以及3D細胞培養和器官晶片系統的創新正在成為確保更廣泛的消費者基礎並擴大市場的動力,同時遵守消費者安全標準。
主要市場統計 | |
---|---|
基準年[2023] | 122.1億美元 |
預測年份 [2024] | 134.9億美元 |
預測年份 [2030] | 252.1億美元 |
複合年成長率(%) | 10.90% |
技術 體外毒理學測試 技術選擇的優先順序很大程度取決於特定的研究需求
細胞培養技術是體外毒性測試的基石。這些技術通常涉及在嚴格控制的條件下培養細胞,以研究毒性機制並預測潛在的毒性作用。這些技術通常用於現實測試模型和複雜的毒性分析。高通量技術透過自動化樣品處理和資料分析來加速體外毒性測試。分子影像提供了一種在細胞和分子層面上可視化和監測生物過程的非侵入性方法,這對於了解物質的毒性非常重要。組學技術涵蓋基因組學、蛋白質組學和代謝體學,探索有毒物質影響的基本生物學途徑。
方法 細胞測定在毒性、藥物動力學和動態研究中的重要性
體外毒性測試已經透過多種方法不斷發展,這些方法在確定物質的毒性和開發更安全的藥物化合物方面發揮著重要作用。對於體外毒性測試,生化測定是製藥、生物技術和研究實驗室的首選方法,因為它們詳細說明了目標分子和小分子化合物之間的相互作用。此方法著重於早期識別潛在有毒物質,具有成本效益和時間效益。酶測定、受體結合測定和次級訊號化驗等生化測定為了解這些相互作用的性質和潛在影響提供了必要的見解。細胞測定是體外毒性測試的重要組成部分,因為它們提供了細胞對化合物和治療的反應的概述。它更準確地模仿人類生理學,因此在基於需求的偏好方面得分更高。這些測定可用於確定新化合物的毒性、藥物動力學和動態。使用器官型或組織切片培養的體外方法是安全性評估的首選方法,尤其是器官特異性毒性測試。利用電腦模擬模型進行毒性評估的In Silico方法正迅速普及,因為它們是非侵入性的、具有成本效益的,並且允許快速測試。
應用:注意力集中在改進測試方法,同時提供滿足行業特定要求的準確可靠的結果。
由於 3D 人體皮膚模型的創建和對動物測試的依賴減少,整個行業中皮膚相關產品和化學物質的使用不斷增加,皮膚毒性變得越來越重要。內分泌干擾領域研究可能導致荷爾蒙失衡並影響健康和發育的物質。主要醫療保健供應商正在與環境機構合作,加強對潛在內分泌干擾物的篩檢,並鼓勵化學和生態學毒性控制產業。眼毒理學是對可能損害眼組織的物質進行研究,並提供準確且可重複的眼部毒性測試產品,以提高眼部專用產品的安全性。系統毒理學評估物質對各種身體系統的影響。此測試解決方案是一項用於評估器官毒性風險、降低藥物製造成本和開發時間的新服務。總體而言,體外毒性測試為安全評估提供了巨大的潛力和巨大的成長機會。過去兩年,我們在改進測試方法方面取得了重大進展,同時提供了滿足行業特定要求的準確可靠的結果。
最終用途:試管內測試積極用於食品和製藥領域,以確保安全標準。
試管內毒性測試可確保各個領域的安全,每個領域都有特定於行業的方法來滿足其不同的需求。化學公司透過發布專門的化學分析體外測試平台,繼續推進體外評估,以確認有害影響並保護人類健康和生態系統。消費品產業依靠毒性測試來確保客戶安全,同時分析護膚和家用產品的過敏性和刺激性。食品製造商正在採用體外毒性測試,透過先進的體外病原體鑑定試劑套件來評估添加劑的安全性。製藥科學中的體外測試對於藥物發現非常重要,它透過利用體外可用的物質來促進對毒性和功效的理解。安全標準和客戶信心的提高很大程度上歸功於體外毒性測試,每項進步都反映了行業不斷變化的需求。
區域洞察
美洲,特別是美國和加拿大,由於慢性病的流行對生物醫學研究的高需求,在體外毒性測試領域處於領先地位。政府措施和市場領導的強大影響力進一步鞏固了其地位。歐洲也制定了《化學品註冊、評估、授權和限制 (REACH) 法案》等法律規章,刺激了對高效可靠測試方法(特別是危害識別和風險評估)的投資,並傾向於試管內測試。儘管仍處於起步階段,但由於醫療保健領域投資增加以及迫切需要遵守全球健康和安全法規,中東和非洲也是潛力巨大的市場。中國、日本和印度等亞太國家不斷變化的消費需求正在推動該地區體外測試的成長。例如,中國增加了對生物醫學研究的資助,日本則受益於強大的醫療保健框架和顯著的研究促進政策。全球舉措、專利活動和研究進展,例如歐盟的地平線 2020計劃和中國國家自然科學基金,強調了體外毒性測試的重要作用。
FPNV定位矩陣
FPNV定位矩陣對於評估體外毒性測試市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可以對體外毒理學測試市場中供應商的現狀進行深入而深入的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4.競爭評估及資訊:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況、製造能力等進行綜合評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1.體外毒性測試市場規模及預測如何?
2.在體外毒理學測試市場的預測期內,有哪些產品、細分市場、應用和領域需要考慮投資?
3. 體外毒性測試市場的技術趨勢和法規結構是什麼?
4.體外毒性測試市場主要廠商的市場佔有率為何?
5. 進入體外毒性測試市場的合適型態和策略手段是什麼?
[182 Pages Report] The In-Vitro Toxicology Testing Market size was estimated at USD 12.21 billion in 2023 and expected to reach USD 13.49 billion in 2024, at a CAGR 10.90% to reach USD 25.21 billion by 2030.
The in-vitro toxicology testing market employs cell cultures and organ cultures for toxicity evaluation of substances such as chemicals, drugs, and food. This innovative approach, used in pharmaceuticals, cosmetics, and the food industry, offers significant precision, repeatability, and speed benefits. The market is thriving due to advancements in testing methods, a rising ethos against animal testing, and the increased need for cost-effective safety measures. Potential growth areas lie in using in-vitro models in drug and therapeutic development, which closely mimic human biochemistry and minimize the occurrence of unsuccessful clinical trials. Further, the progress in genomics and proteomics presents considerable growth opportunities. The market, however, faces challenges such as the complexity of test data interpretation, the difficulty of replicating in-vivo conditions, and regulatory intricacies, all of which contribute to high operational costs. Future business growth hinges on focused research to enhance the predictive accuracy of in-vitro test systems while lowering costs. Collaborations with regulatory agencies for test recognition and approval advances in computational biology and genomics and innovations in 3D cell culture and organ-on-a-chip systems collectively drive market expansion, ensuring a broad consumer base is achieved while upholding consumer safety standards.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 12.21 billion |
Estimated Year [2024] | USD 13.49 billion |
Forecast Year [2030] | USD 25.21 billion |
CAGR (%) | 10.90% |
Technology: Preference for in-vitro toxicology testing technology selection largely depends by specific research needs
Cell culture technologies serve as the cornerstone of in-vitro toxicology testing. They often involve growing cells under carefully controlled conditions to investigate the mechanisms of toxicity and predict potential toxic effects. These technologies are typically employed for realistic test models and intricate toxicity analysis. High throughput technology expedites in-vitro toxicology testing by automating sample processing and data analysis. Molecular imaging offers a non-invasive method to visualize and monitor biological processes at the cellular and molecular level, critical for understanding substance toxicity. OMICS technology, which encapsulates genomics, proteomics, and metabolomics, among others, probes into the underlying biological pathways affected by toxic substances.
Method: Cellular assays gained importance in toxicity, pharmacokinetics and pharmacodynamics in vitro toxicology testing
In-vitro toxicology testing evolves through multiple methodologies, each playing a crucial role in determining the toxicity of substances and developing safer pharmaceutical compounds. In in-vitro toxicology testing, biochemical assays are the most favored methods by pharmaceutical, biotech, and research institutions since they involve detailed investigation of the interactions between a target and a small molecule. This technique predominantly focuses on identifying potential toxic substances early, making it cost and time-efficient. Biochemical assays such as enzymatic assays, receptor-binding assays, and second messenger assays provide necessary insights into the nature of these interactions and potential impacts. Cellular assays hold an imperative space in in-vitro toxicology testing by providing a panoramic view of the cell's response to a compound or a treatment. They score high on need-based preference as they mimic human physiology more accurately. These assays help determine new compounds' toxicity, pharmacokinetics, and pharmacodynamics. Ex-vivo methods, using organotypic or slice cultures of tissues, are favored for safety evaluations, especially for organ-specific toxicity testing. In Silico processes utilize computer-simulated models for toxicity evaluation, a burgeoning preference owing to their non-invasive, cost-effective, and speedy testing abilities.
Application: Rising focus on improving testing methods while delivering accurate, reliable results catering to industry-specific requirements
Dermal toxicity gained importance due to the growing use of skin-related products and chemicals across industries due to 3D human skin model creation and reducing the dependence on animal testing. The endocrine disruption domain studies substances that can cause hormonal imbalances, impacting health and development. Major healthcare vendors collaborate with environmental agencies to boost screening of potential endocrine disruptors, encouraging chemical and ecological toxicity control industries. Ocular toxicity involves studying substances that can harm eye tissue, as it provides accurate and reproducible ocular toxicity testing products, ensuring greater safety for eye-specific products. Systemic toxicology evaluates the impact of substances on various body systems. This testing solution is a novel service for assessing organ toxicity risks, reducing costs and development time in drug manufacturing. Overall, in-vitro toxicology testing offers significant safety evaluation potential with vast growth opportunities. The last two years saw remarkable advancements aimed at improving testing methods while delivering accurate, reliable results catering to industry-specific requirements.
End-Use: In vitro testing used vigorously in food and pharma sectors to ensure safety standards
In-vitro toxicology trials ensure safety across diverse sectors, with specific methods adopted for each industry to address their different needs. Chemical corporations continually advance in-vitro evaluations to ascertain hazardous effects and safeguard human health and the ecosystem by releasing a specialized in-vitro testing platform for chemical profiling. Consumer product industries take advantage of toxicology tests to guarantee customer safety while analyzing allergenicity and irritancy in skincare and household items. Food manufacturers employ in-vitro toxicology testing for the safety evaluation of their additives through advanced in-vitro testing kits for pathogen identification. Critical for drug discovery, in-vitro testing in pharmacy facilitates the understanding of toxicity and efficacy by utilizing its in-vitro offerings. Enhancement of safety standards and customer trust can be attributed significantly to in-vitro toxicology testing, with each advancement mirroring the evolving industry needs.
Regional Insights
The Americas, particularly the U.S., and Canada, spearheading the in vitro toxicology testing field due to high biomedical research demand from high chronic disease prevalence. Government initiatives and the robust presence of market leaders further bolster their position. Europe also leans towards in-vitro testing, with legislation including Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) law spurring investment into efficient and reliable testing methods, especially for hazard identification and risk assessment. Despite being nascent, the Middle East and Africa also demonstrate a high potential market, encouraged by the increased healthcare sector investment and the pressing need to comply with global health and safety regulations. Dynamic consumer demands in the Asia Pacific, including countries such as China, Japan, and India, propel the growth of in-vitro testing in this region. For example, China's funding for biomedical research is increasing, Japan benefits from a sturdy healthcare framework and notable pro-research policies, and healthcare investors are courting India's burgeoning economy. Global initiatives, patenting activities, and research advancements, such as the EU's Horizon 2020 project and China's National Natural Science Foundation funding, underscore the indispensable role of in-vitro toxicology testing.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the In-Vitro Toxicology Testing Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the In-Vitro Toxicology Testing Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the In-Vitro Toxicology Testing Market, highlighting leading vendors and their innovative profiles. These include Abbott Laboratories, Agilent Technologies, Inc., Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Bio-Techne Corporation, BioIVT LLC, Charles River Laboratories International, Inc., Creative Bioarray, ERBC Group, Eurofins Scientific SE, Evotec SE, F. Hoffmann-La Roche AG, Gentronix Limited, HD Biosciences Co., Ltd., INDIGO Biosciences, Inc., Inotiv, Inc., InSphero AG, Intertek Group PLC, Laboratory Corporation of America Holdings, LAUS GmbH, LGC Limited, Merck KGaA, Microbac Laboratories Inc., Oroxcell SAS, Promega Corporation, Qiagen N.V., SGS SA, Thermo Fisher Scientific Inc., Toxys, Inc., Vimta Labs Ltd., and WuXi AppTec.
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the In-Vitro Toxicology Testing Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the In-Vitro Toxicology Testing Market?
3. What are the technology trends and regulatory frameworks in the In-Vitro Toxicology Testing Market?
4. What is the market share of the leading vendors in the In-Vitro Toxicology Testing Market?
5. Which modes and strategic moves are suitable for entering the In-Vitro Toxicology Testing Market?