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市場調查報告書
商品編碼
2133431
動脈瘤夾市場規模、佔有率和趨勢分析 |全球| 2026–2032 | 包括鈦合金和鈷合金動脈瘤夾Aneurysm Clip Market Size, Share & Trends Analysis | Global | 2026-2032 | Includes: Titanium Aneurysm Clips and Cobalt Alloy Aneurysm Clips |
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2025年全球動脈瘤夾市場規模為5,900萬美元。預計該市場將以-0.7%的複合年成長率萎縮,到2032年達到5,600萬美元。
本報告涵蓋全球動脈瘤夾市場,按材質(鈦合金和鈷合金)和器械類型(臨時性和永久性)進行分類。該報告對手術量、銷售量、平均售價、市場規模、成長率和企業市場占有率進行了定量分析,包括截至2022年的歷史數據和截至2032年的預測數據。
全球動脈瘤夾市場銷售量預計將在預測期內逐步下降,反映出微創血管內治療正逐漸取代外科手術夾閉,成為結構性治療選擇。平均售價(ASP)也因價格壓力和市場成熟而呈現下降趨勢。這些因素綜合表明,到2032年,整體市場規模將緩慢但穩定地萎縮。
在某些臨床情況下,由於動脈瘤的形態、位置和患者特徵等原因,血管內治療不適用,而動脈瘤夾閉術仍是重要的治療選擇。對於頸寬的動脈瘤、解剖位置合適的動脈瘤以及可透過單次開顱手術治療的多發性脈搏瘤病例,動脈瘤夾閉術仍然是首選治療方案,這為整體市場下滑提供了穩定的支撐。
市場概覽
全球動脈瘤夾閉術市場是神經血管器械領域內一個成熟且逐漸萎縮的市場區隔。動脈瘤夾閉術需要開顱手術以確保能夠直接手術到達動脈瘤部位,曾是顱內動脈瘤的主要治療方法。過去20年間,由於血管內卷取的普及和不斷改進的囊內裝置的引入,全球動脈瘤夾閉術的數量顯著下降。預測期內-0.7%的複合年成長率表明,該市場正經歷可控的下滑而非急劇萎縮,在特定解剖適應症下,仍會保留一定數量的動脈瘤夾閉術,因為在這些情況下,手術入路仍然適用。
血管內神經血管治療技術的興起是重塑這個市場的主要驅動力。栓塞和導管介入治療屬於微創治療,無需開顱手術,與外科夾閉術相比,可顯著縮短住院時間。血管內治療已成為大多數動脈瘤的第一線治療方案,無論動脈瘤的位置或形態如何。隨著血管內治療技術臨床經驗的累積和醫生培訓的不斷深入,需要進行動脈瘤夾閉術的病例數量正在穩步下降。
在某些不適合血管內治療的情況下,動脈瘤夾閉術仍具有明確的臨床應用價值。對於瘤頸比小於1.5的寬頸動脈瘤、易於透過手術入路的腦中動脈瘤以及可透過單次開顱手術治療的多發性脈搏瘤,動脈瘤夾閉術仍然是首選治療方案。 ISAT試驗的長期數據也表明,與動脈瘤夾閉術相比,栓塞治療的再出血率更高,這支持在年輕患者中繼續使用手術夾閉術,因為修復的持久性具有長期的臨床價值。
新型囊內裝置正在加劇競爭壓力,即使在以往首選夾閉術的適應症中也是如此。 WEB動脈瘤栓塞系統透過將血液從動脈瘤周圍引流出來促進血液凝固,主要用於治療大型或巨大型寬頸腦動脈瘤,這類動脈瘤曾是手術夾閉術最有希望的適應症。隨著裝置及其競爭對手累積臨床經驗,並擴大其核准適應症,夾閉術是唯一可行治療方案的病例比例持續下降,導致市場持續萎縮。
動脈瘤的形態和位置
儘管動脈瘤夾閉手術總體呈下降趨勢,但仍有相當數量的病例因其形態和解剖特徵不適合血管內治療,而繼續採用動脈瘤夾閉術。對於頸寬的動脈瘤以及瘤體與瘤頸比小於1.5的動脈瘤,當維持動脈瘤囊內彈簧圈的穩定性較為困難時,動脈瘤夾閉術是首選治療方案。此外,當一次開顱手術可以處理多個動脈瘤時,動脈瘤夾閉術也是首選方法,因為它允許在一次手術中治療多個病變。特別是大腦中動脈瘤,由於該部位的手術入路相對容易,因此通常採用動脈瘤夾閉術。這些形態學適應症預計不會消失,即使血管內治療在這些適應症中的佔有率增加,動脈瘤夾閉術仍將繼續提供穩定的治療基礎,從而抑制整體市場的萎縮。
永久性修剪的長期效果
動脈瘤夾閉術的永久性對於某些患者群體而言具有顯著的臨床效益。血管內治療相關的併發症,例如彈簧圈壓迫、彈簧圈移位以及需要再次治療或更換分流器等,在永久性手術夾閉術中均不存在。 ISAT試驗的長期數據顯示,與夾閉術相比,彈簧圈栓塞術的再出血率更高,這證明了在年輕患者中優先選擇夾閉術的合理性,因為對於這些患者而言,修復效果的持久性至關重要。這種長期療效的優點確保了動脈瘤夾閉術在神經外科治療決策過程中將繼續發揮重要作用,即使血管內治療在全球佔據了手術總量的絕大多數。
微創血管內治療技術
過去20年,顱內動脈瘤的血管內治療取得了顯著進展,且這項發展動能仍在加速。與需要開顱手術的動脈瘤夾閉術相比,血管內治療具有微創的特點,可顯著縮短患者的住院時間。對於絕大多數患者和動脈瘤類型而言,栓塞和囊內裝置治療的微創性和快速恢復優勢超過了動脈瘤夾閉術的長期療效。隨著醫生在血管內治療技術方面的培訓不斷擴展,以及臨床結果數據持續支持微創治療方法在多種適應症中的應用,預計在預測期內,動脈瘤夾閉術的數量將繼續逐步下降。
新技術的引入
新型囊內栓塞裝置正日益取代外科夾閉術,尤其是在治療寬頸和複雜動脈瘤方面,而這些動脈瘤先前曾是外科夾閉術最常見的適應症之一。 WEB動脈瘤栓塞系統於2019年1月獲得美國食品藥物管理局(FDA)的上市前批准,在無需開顱手術的情況下治療大型或巨大型寬頸腦動脈瘤方面取得了商業性成功。 Cerus Endovascular公司也已啟動一項旨在與WEB系統直接競爭的裝置的臨床試驗,這表明囊內栓塞技術正在取得進一步發展。隨著這些裝置臨床證據的累積和適應症的擴大,預計它們將進一步取代外科夾閉術,並導致腦動脈瘤夾閉術市場持續萎縮。
The global aneurysm clip market was valued at $59 million in 2025. The market is expected to decline at a compound annual growth rate (CAGR) of -0.7%, reaching $56 million by 2032.
This report covers the global market for aneurysm clips, segmented by material type into titanium and cobalt alloy, and by device modality into temporary and permanent. The report quantifies procedure numbers, unit sales, average selling prices (ASPs), market values, growth rates, and company shares, with historical data back to 2022 and forecasts through 2032.
Unit sales in the global aneurysm clip market are expected to gradually decline over the forecast period, reflecting a structural shift toward minimally invasive endovascular alternatives to surgical clipping. ASPs are also trending downward due to pricing pressures and market maturity. Together, these factors contribute to a modest but consistent contraction in overall market value through 2032.
Clipping retains procedural relevance in specific clinical scenarios where aneurysm morphology, location, and patient characteristics make endovascular approaches less suitable. Wide-necked aneurysms, anatomically favorable surgical sites, and cases involving multiple aneurysms reachable through a single craniotomy remain areas where clipping is preferred, providing a stable procedural floor that limits the pace of overall market decline.
Market Overview
The global aneurysm clip market is a mature and gradually contracting segment within the broader neurovascular device space. Aneurysm clipping, which requires a craniotomy to provide direct surgical access to the aneurysm, was once the primary treatment for intracranial aneurysms. Over the past two decades, the growth of endovascular coiling and the introduction of increasingly capable intrasaccular devices have substantially reduced the volume of clipping procedures performed globally. The -0.7% CAGR over the forecast period reflects a market in managed decline rather than acute contraction, with a persistent procedural base maintained by specific anatomical indications that continue to favor the surgical approach.
The shift toward endovascular neurovascular techniques has been the dominant force reshaping this market. Coiling and catheter-based approaches are minimally invasive, require no craniotomy, and significantly reduce hospital length of stay compared to surgical clipping. For the majority of aneurysm locations and morphologies, endovascular treatment has become the preferred first-line approach. As clinical experience with endovascular techniques has broadened and physician training has expanded, the number of aneurysm cases directed toward clipping has steadily narrowed.
Clipping retains a defined clinical role in specific cases where endovascular approaches are less suitable. Wide-necked aneurysms with a dome-to-neck ratio below 1.5, middle cerebral artery aneurysms where surgical access is favorable, and cases involving multiple aneurysms accessible through a single craniotomy are settings where clipping continues to be preferred. Long-term data from the ISAT trial also showed that coiling carries a higher re-hemorrhage rate compared to clipping, supporting continued use of surgical clips in younger patients where the permanence of the repair has long-term clinical value.
Newer intrasaccular devices are adding further competitive pressure in indications that were historically considered clip-preferred. The WEB aneurysm embolization system, which redirects blood away from the aneurysm to promote clotting, is primarily indicated for large or giant wide-necked brain aneurysms that were once among the strongest candidates for surgical clipping. As this and competing devices build clinical track records and expand approved indications, the proportion of cases where clipping is the only viable option continues to narrow, contributing to the market's ongoing contraction.
Market Drivers
Aneurysm Morphology and Location
Despite the overall decline in clipping procedures, a significant number of cases will continue to be treated with aneurysm clips because of morphological and anatomical characteristics that make endovascular approaches less suitable. Clipping is preferred for wide-necked aneurysms or those with a dome-to-neck ratio below 1.5, where maintaining coil stability within the aneurysm sac is difficult. When multiple aneurysms can be accessed through a single craniotomy, clipping is also the preferred approach as it allows treatment of multiple lesions in a single surgical session. Middle cerebral artery aneurysms in particular tend to be clipped due to the relative ease of surgical access in that location. These morphological indications are not expected to disappear, providing a stable procedural base that limits the overall pace of market decline, even as endovascular alternatives capture an increasing share of eligible cases.
Long-Term Efficacy of Permanent Clipping
The permanence of aneurysm clipping is a meaningful clinical advantage in specific patient populations. Complications associated with endovascular treatment, including coil compaction, coil migration, and the need for retreatment or shunt replacement, are not concerns with permanent surgical clipping. Long-term data from the ISAT trial found that coiling was associated with a higher rate of re-hemorrhage compared to clipping, which informs treatment decisions in favor of clipping for younger patients where the durability of the repair over many decades is a priority. This long-term efficacy argument ensures that aneurysm clips remain part of the neurosurgical treatment decision process even as endovascular approaches dominate aggregate procedure volumes globally.
Market Limiters
Minimally Invasive Endovascular Techniques
The trend toward endovascular neurovascular treatment for intracranial aneurysms has made substantial progress over the past twenty years and continues to strengthen. Endovascular approaches are minimally invasive and significantly reduce patient hospital length of stay compared to aneurysm clipping, which requires a craniotomy. For the majority of patients and aneurysm presentations, the reduced procedural invasiveness and faster recovery associated with coiling or intrasaccular device treatment outweigh the long-term efficacy advantages of clipping. As physician training in endovascular techniques continues to expand and clinical outcomes data continues to support minimally invasive approaches across a broadening range of indications, the volume of clipping procedures is expected to continue its gradual decline throughout the forecast period.
Introduction of New Technology
Newer intrasaccular devices are specifically displacing aneurysm clips in cases where wide-necked and complex aneurysms were historically among the most common indications for surgical clipping. The WEB aneurysm embolization system, which received FDA premarket approval in January 2019, has found commercial success in treating large or giant wide-necked brain aneurysms without the need for open surgery. Cerus Endovascular has also initiated clinical trials for a device designed to compete directly with the WEB system, indicating that further development in intrasaccular embolization technology is underway. As these devices expand their clinical evidence base and approved indications, they are expected to capture additional procedural share from surgical clipping and contribute to the ongoing contraction of the aneurysm clip market.
Market Coverage and Data Scope
Markets Covered and Segmentation
Competitive Analysis
Mizuho was the leader in the global aneurysm clip market in 2025. The company's Sugita Titanium 2 aneurysm clip features an ultra-slim profile designed to improve handling and provide a clearer surgical sightline during the clipping procedure. This design characteristic is particularly valuable in the confined operating environment of a neurosurgical craniotomy, where visualization and instrument maneuverability directly influence procedural safety and outcomes. Mizuho's specialized focus on neurosurgical instrumentation supports its leadership in a segment where clinical heritage and product reliability are primary purchasing criteria for neurosurgeons.
Peter Lazic was the third-leading and newest competitor in the global aneurysm clip market in 2025. The company offers approximately 220 different aneurysm clip variants made from titanium alloys, providing one of the broadest product ranges in the segment in terms of clip geometry and configuration. The company is also experimenting with PEEK (polyether ether ketone), an MRI-safe plastic material, as a potential future direction for clip construction. This positions Peter Lazic as an innovator within a declining market, with PEEK's material properties and MRI compatibility representing a differentiated development direction relative to established metal clip suppliers.
Technology and Practice Trends
Geography
This report provides global coverage across North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa.
The Global Aneurysm Clip Market Report from iData Research answers these questions with procedure-aware models, company share analysis, and pricing detail. Use it to understand the pace and structure of market contraction, benchmark competitors, and identify the residual procedural segments where aneurysm clips retain durable clinical and commercial relevance.