全球內視鏡黏膜下剝離術（ESD）刀市場：市場規模、佔有率和趨勢分析（2026-2032 年）

預計2025年，全球內視鏡黏膜下剝離術（ESD）刀市場規模將超過3.59億美元。預計到2032年，該市場將以7.6%的複合年成長率成長，達到約6億美元。

本報告涵蓋內視鏡黏膜下剝離術（ESD）刀，這是一種能夠實現微創切除胃腸道病變的關鍵附件。報告量化了ESD刀的銷售、平均售價（ASP）、市場價值、成長率和企業市場占有率。此外，報告還涵蓋了市場趨勢和促進因素、近期併購活動以及技術發展。報告提供了2022年至2024年的歷史數據以及至2032年的預測數據。

該報告反映了 ESD 技術和刀具設計的進步如何推動手術的普及，改善患者的治療效果，並隨著醫院和臨床醫生轉向創傷較小的治療途徑，支持市場的持續擴張。

市場概覽

內視鏡黏膜下剝離術（ESD）刀的設計目的是為了精確、可控地切除早期胃腸道病變，包括腫瘤和息肉，而無需進行開放性手術。 ESD 使醫生能夠將病變組織從黏膜下層完整剝離，從而提高診斷準確性並最大限度地減少復發。

自1990年代末期引進以來，器械設計、影像技術和操作者培訓方面的創新顯著推動了該手術的發展。 ESD刀仍然是這些手術的基石，它提供了安全有效切除所需的精確度和多功能性。

尖端設計、導電性和控制機制的進步提高了內視鏡黏膜下剝離術（ESD）刀的可靠性，使醫生能夠以更少的併發症進行一致的整塊切除。隨著越來越多的醫院安裝相容ESD的系統以及臨床醫生技能的提高，全球ESD手術總量持續成長。

ESD技術的日益普及反映了微創內視鏡手術的整體發展趨勢。與傳統開放性手術或腹腔鏡手術相比，ESD具有住院時間更短、患者不適感更少、恢復更快等優勢。預計這些臨床和經濟效益將持續推動市場需求，直至2032年。

隨著視覺化和電外科技術的創新，ESD有望變得更加複雜，並成為許多早期胃腸道癌症和癌前病變的首選治療方法，從而提高ESD刀在全球胃腸內視鏡市場的重要性。

市場促進因素

單塊切除

ESD刀的一個關鍵優勢是能夠進行整塊切除，與分塊切除技術相比，可以進行更準確的組織學診斷，並降低復發風險。

臨床研究表明，使用內視鏡黏膜下剝離術（ESD）切除的腫瘤中，96%可整塊切除，且後續觀察期間未見局部復發。完全切除的可能性轉化為更佳的長期治療效果和醫師的信心，使得ESD越來越成為早期胃腸道病變的首選治療方法。

改進的刀具技術

• 自1998年首次問世以來，ESD刀一直在不斷改進。現代ESD刀大致可分為兩大類：鈍頭刀和截尖刀。每種刀型都有獨特的操作優勢，取決於病灶的位置和黏膜下層的厚度。

旋轉控制、可調節長度鞘套和多功能電極等創新提高了精度並縮短了手術時間，製造商不斷提供各種刀尖形狀和附件，提高了對不同病變類型和器官位置的適應性。

這些改進提高了手術的成功率和安全性，使內視鏡醫師能夠更穩定地進行 ESD 手術，從而在全球範圍內廣泛應用。

性價比高

ESD手術可達到與開放性手術或腹腔鏡手術相當的療效，但費用卻低得多。無需進行完全的外科手術即可達到根治性切除，從而減少住院時間、麻醉需求和術後併發症。

對於成本受限的醫院和醫療保健系統而言，靜電除塵術 (ESD) 提供了一種有效的替代方案，既能顯著節省成本，又能保持臨床療效。隨著支付方和政策制定者認知到這些優勢，越來越多的市場開始逐步擴大 ESD 手術的報銷範圍。這一趨勢進一步增強了 ESD 技術的經濟效益，並提高了對高品質 ESD 手術刀的需求。

簡化流程並擴大培訓

工作流程效率的提高和培訓計畫的日益普及正在推動醫生廣泛採用內視鏡黏膜下剝離術（ESD）。模擬工具、導師網路和專門的ESD課程使內視鏡醫師能夠在獨立進行手術前安全地累積經驗。

對專家教育的這項投資縮短了學習曲線，提高了操作成功率，從而支持了整個 ESD 市場的成長，並促進了 ESD 刀具在全球範圍內的普及。

市場限制

併發症風險

儘管內視鏡黏膜下剝離術（ESD）具有顯著優勢，但與內視鏡黏膜切除術（EMR）等其他手術相比，其穿孔和出血的風險相對較高。 ESD 的複雜性要求操作者俱備精準的控制能力和豐富的經驗，訓練不足可能會增加併發症的發生率。

對於較小或較易觸及的病變，一些醫生仍然偏好 EMR，因為它風險較低，但對潛在併發症的擔憂可能會限制 ESD 專家和資源有限的中心採用 EMR。

靜電放電防護專業人員數量有限

成功的環境永續發展教育需要專門的技能，在許多地區，受過訓練的環境永續發展教育專家的數量有限，尤其是在日本和西方的一些學術中心之外。

因此，患者通常被轉診至外科或電子病歷科，而非內視鏡黏膜下剝離術（ESD）。擴大培訓和指導機會對於更廣泛地推廣應用至關重要。如果沒有更多培訓機會和更完善的報銷政策，某些市場的手術量成長可能仍將保持低迷。

採用障礙和資源需求

與標準內視鏡手術相比，ESD 手術通常需要更長的手術時間和專門的設備，包括需要專門的電外科設備、先進的影像處理和麻醉支持，這可能會限制其在資源匱乏的中心的普及。

此外，在某些市場，健保報銷機制可能尚未完全涵蓋內視鏡黏膜下剝離術（ESD），這降低了醫院投資必要基礎設施的獎勵。解決這些系統層面的障礙對於維持長期成長至關重要。

目標市場和數據範圍

定量範圍

市場規模、市佔率、市場預測、成長率、銷售量、平均售價

定性範圍

影響靜電放電防護刀具需求的成長趨勢、限制因素、競爭對手分析及SWOT分析、併購活動、公司簡介及產品系列、FDA召回事件、顛覆性技術、疾病概述

時期

基準年為2025年，預測期間為2026-2032年，歷史資料為2022-2024年。

數據來源

對產業領導者的初步調查、政府醫生資料、監管文件、醫院採購資料、進出口資料庫、iData Research內部資料庫

方法注記

收入模型是根據銷售量乘以平均售價計算得出的，並根據一次性及可重複使用設備的程序數據和更換假設檢驗。

競爭分析

Olympus Corporation在2025年以絕對市佔率引領全球靜電放電防護刀市場。其領先地位得益於豐富的產品系列和悠久的內視鏡創新歷史。靜電放電防護刀最初在日本流行起來，Olympus憑藉早期應用優勢迅速確立了市場主導地位。

在奧林巴斯公司的眾多產品中，ITknife nano尤其引人注目。這款一次性電外科刀針對薄層黏膜下層和大腸手術進行了最佳化，具有出色的操作性和抗感染性。Olympus正透過持續的研發和臨床醫生培訓舉措，在全球範圍內拓展該產品線，並鞏固其市場地位。

ERBE Elektromedizin GmbH 在電外科手術刀市場排名第二。其 HybridKnife 將切割和凝血功能整合於單一器械中，無需更換器械即可實現多種功能。這種雙重功能簡化了醫院的庫存管理，並提高了手術效率。 HybridKnife 的多功能性以及與 ERBE 先進電外科產生器的兼容性，鞏固了該公司作為全球領先供應商的地位。

波士頓科學公司憑藉其多元化的高性能內視鏡黏膜下剝離刀產品組合，在2025年排名第三。該公司產品設計著重精準性、耐用性和人體工學，旨在提升醫師在黏膜下剝離術中的操作便利性。波士頓科學公司持續投資內視鏡黏膜下剝離術專用技術研發，進一步鞏固其在先進內視鏡市場的競爭地位。

整體而言，ESD刀市場集中在少數幾家擁有成熟內視鏡產品組合和全球分銷網路的跨國公司手中。競爭主要體現在價格、技術創新、培訓合作以及工作流程整合等。

科技與臨床趨勢

多功能 ESD 刀具結合了切割、注射和凝血功能，減少了更換器械的需要，提高了效率和安全性。

一次性刀具設計越來越受歡迎，以防止交叉污染並簡化再處理流程。

水刀輔助和旋轉刀片等尖端設計的進步提高了精度並縮短了手術時間。

高解析度窄頻視覺化系統增強了影像融合，從而能夠更準確地勾勒出病灶邊界和黏膜下層。

擴大和標準化的培訓持續推動全球範圍內的普及，模擬平台和導師制計劃幫助臨床醫生更快地熟練相關技能。

區域指南正在更新，將 ESD 納入早期胃腸道癌症的第一線治療方法。

地區

本期內容涵蓋全球，包括北美、歐洲、亞太地區、拉丁美洲以及中東和非洲。

調查方法附錄與簡稱

目錄

圖表清單

圖表列表

調查方法

全球關稅的影響

內視鏡黏膜下剝離術（ESD）刀市場

• 摘要整理
  • 全球內視鏡黏膜下剝離術（ESD）刀市場概覽
  • 競爭分析
  • 目標區域
• 介紹
• 市場分析與預測
• 推動和阻礙因素
• 競爭市佔率分析

簡稱

The global endoscopic submucosal dissection (ESD) knife market was valued at over $359 million in 2025. The market is projected to grow at a compound annual growth rate (CAGR) of 7.6 percent, reaching approximately $600 million by 2032.

This report covers endoscopic submucosal dissection knives, key accessories that enable minimally invasive removal of gastrointestinal lesions. It quantifies unit sales, average selling prices (ASPs), market values, growth rates, and company shares, and includes market drivers and limiters, recent mergers and acquisitions, and technology trends. The report provides historical data from 2022 to 2024 and forecasts through 2032.

The scope reflects how advancements in ESD techniques and knife designs are driving procedural adoption, improving patient outcomes, and supporting continued market expansion as hospitals and clinicians transition toward less invasive treatment pathways.

Market Overview

Endoscopic submucosal dissection (ESD) knives are designed to perform precise and controlled resections of early-stage gastrointestinal lesions, including tumors and polyps, without requiring open surgery. ESD enables physicians to dissect lesions from the submucosal layer in one piece, improving diagnostic accuracy and minimizing recurrence.

Since the introduction of ESD in the late 1990s, the procedure has evolved significantly through innovations in device design, imaging, and operator training. ESD knives have become the cornerstone of these procedures, providing the precision and versatility required for safe and effective resections.

Advances in tip design, electrical conductivity, and control mechanisms have enhanced the reliability of ESD knives, allowing physicians to achieve consistent en bloc resections with fewer complications. As more hospitals adopt ESD-capable systems and as clinician proficiency improves, the overall number of ESD procedures performed globally continues to rise.

The growing acceptance of ESD reflects the broader movement toward minimally invasive endoscopic therapies. Compared to traditional open or laparoscopic surgery, ESD offers shorter hospital stays, reduced patient discomfort, and faster recovery times. These clinical and economic benefits are expected to continue fueling market demand through 2032.

As innovations in visualization and electrosurgical technology further refine the technique, ESD is expected to become the preferred treatment for many early gastrointestinal cancers and precancerous lesions, reinforcing the importance of ESD knives within the global GI endoscopy market.

Market Drivers

Single-Fragment Resection

One of the defining advantages of ESD knives is their ability to achieve single-fragment (en bloc) resection. Removing lesions in one piece enables more accurate histological diagnosis and lowers recurrence risk compared to piecemeal resection techniques.

Clinical studies have shown that as many as 96 percent of tumors resected with ESD knives are removed in one piece, with no local recurrence observed during follow-up. The ability to secure complete resections supports improved long-term outcomes and greater confidence among physicians, making ESD knives increasingly preferred for early-stage gastrointestinal lesions.

Improved Knife Technology

• Since their first introduction in 1998, ESD knives have undergone continuous refinement. Modern knives fall into two main categories: blunt-tip designs and tip-cutting designs. Each type offers unique procedural advantages depending on lesion location and thickness of the submucosal layer.

Innovations such as rotational control, adjustable sheath lengths, and multi-functional electrodes have increased precision and reduced procedure time. Manufacturers continue to expand the range of knife tip geometries and attachments, improving versatility across lesion types and organ sites.

These improvements enhance procedural success and safety while allowing endoscopists to perform ESD with greater consistency, thereby supporting increased adoption worldwide.

Cost-Effectiveness

ESD offers comparable therapeutic outcomes to open and laparoscopic surgery but at a fraction of the cost. The ability to achieve curative resection without full surgical intervention reduces hospitalization, anesthesia requirements, and post-operative complications.

For hospitals and healthcare systems under cost constraints, ESD represents an effective alternative that delivers measurable savings while maintaining clinical efficacy. As payers and policymakers recognize these advantages, reimbursement for ESD procedures is gradually expanding across more markets. This trend further enhances the economic rationale for ESD adoption, reinforcing demand for high-quality ESD knives.

Procedural Efficiency and Training Expansion

Improved workflow efficiency and increased availability of training programs have encouraged broader physician adoption. Simulation tools, mentorship networks, and dedicated ESD courses now enable endoscopists to gain experience safely before performing procedures independently.

This investment in professional education reduces the learning curve and increases procedural success rates, supporting overall growth of the ESD market and driving higher utilization of ESD knives globally.

Market Limiters

Risk of Complications

Although ESD offers significant benefits, it carries a relatively high risk of perforation and bleeding compared to alternative procedures such as endoscopic mucosal resection (EMR). The complexity of ESD requires precise control and experience, and incomplete training can increase complication rates.

Because EMR presents a lower risk profile, some physicians still prefer it for smaller or more accessible lesions. Concerns about potential complications may limit adoption in centers with limited ESD expertise or resources.

Limited Number of ESD Experts

The successful execution of ESD requires specialized skill. In many regions, the number of trained ESD practitioners remains limited, particularly outside Japan and select academic centers in Europe and North America.

As a result, patients are often referred for surgery or EMR rather than ESD. Expanding access to training and mentorship is essential for broader adoption. Unless training opportunities increase and reimbursement policies improve, procedural volume growth may remain constrained in some markets.

Adoption Barriers and Resource Requirements

ESD procedures typically demand longer operating times and specialized equipment compared to standard endoscopic procedures. The need for dedicated electrosurgical units, advanced imaging, and anesthesia support can limit availability in lower-resource facilities.

In addition, reimbursement structures in certain markets may not yet fully cover ESD procedures, reducing incentives for hospitals to invest in the necessary infrastructure. Addressing these system-level barriers will be critical to sustaining long-term growth.

Market Coverage and Data Scope

Quantitative Coverage

Market size, market shares, market forecasts, growth rates, units sold, and average selling prices.

Qualitative Coverage

Growth trends, limiters, competitive analysis and SWOT for top competitors, mergers and acquisitions, company profiles and product portfolios, FDA recalls, disruptive technologies, and disease overviews that shape demand for ESD knives.

Time Frame

Base year 2025, forecasts 2026 to 2032, historical data 2022 to 2024.

Data Sources

Primary interviews with industry leaders, government physician data, regulatory filings, hospital procurement data, import and export databases, and the iData Research internal database.

Method Note

Revenue is modeled from units multiplied by ASP, validated against procedural data and replacement assumptions for disposable and reusable devices.

Competitive Analysis

Olympus Corporation was the leading competitor in the global ESD knife market in 2025, holding a commanding share. The company's leadership is supported by its broad product portfolio and long history in endoscopic innovation. ESD knives first gained popularity in Japan, where Olympus capitalized on early adoption to establish a dominant presence.

Among its products, the ITknife nano is particularly noteworthy. This single-use electrosurgical knife is optimized for thin submucosal layers and colon procedures, offering excellent maneuverability and infection resistance. Olympus has expanded this product line globally, reinforcing its market position through ongoing R&D and clinician training initiatives.

ERBE Elektromedizin GmbH ranked second in the ESD knife market. The company's HybridKnife combines cutting and coagulation capabilities in one instrument, enabling multiple functions without changing devices. This dual functionality simplifies inventory management for hospitals and improves procedural efficiency. The versatility of the HybridKnife and its compatibility with ERBE's advanced electrosurgical generators have helped solidify the company's position as a leading global supplier.

Boston Scientific Corporation ranked third in 2025, supported by a diverse portfolio of high-performance ESD knives. The company's product designs focus on precision, durability, and ergonomic handling, which enhance physician control during submucosal dissection. Boston Scientific continues to invest in developing ESD-specific technologies to strengthen its competitive presence in the advanced endoscopy market.

Overall, the ESD knife market is concentrated among a small group of multinational companies with established endoscopy portfolios and global distribution networks. Competition centers on innovation, training partnerships, and workflow integration, rather than price alone.

Technology and Practice Trends

Multi-functional ESD knives that combine cutting, injection, and coagulation capabilities are reducing the need for device exchanges, improving efficiency and safety.

Single-use knife designs are becoming more prevalent to prevent cross-contamination and streamline reprocessing workflows.

Advancements in tip design, such as water-jet assistance and rotatable blades, are improving precision and reducing procedure times.

Enhanced imaging integration through high-definition and narrow-band visualization systems allows for better delineation of lesion margins and submucosal layers.

Training expansion and standardization continue to drive global adoption, with simulation platforms and mentorship programs helping clinicians achieve proficiency faster.

Regional guidelines are being updated to include ESD as a first-line treatment option for early-stage gastrointestinal cancers, which is expected to further accelerate procedural growth.

Geography

This edition provides complete global coverage, including North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa.

Methodology Appendix and Acronym Glossary

Why This Report

Where are the largest and fastest-growing opportunities within the global ESD knife market

How are advancements in tip design, imaging, and procedural techniques shaping growth

Which factors are driving the shift toward minimally invasive resections and how do they impact market value

How will the expansion of training programs and cost-effectiveness of ESD influence adoption across regions

What are the key risks to growth, including procedural complexity and limited expert availability

How do Olympus, ERBE, and Boston Scientific position their portfolios and training partnerships to maintain leadership

The Global Endoscopic Submucosal Dissection Knife Market Report from iData Research answers these questions with procedure-based market models, company share analysis, and pricing data. Use it to evaluate market potential, benchmark competitive positioning, and plan strategies for entry or expansion in the advanced GI endoscopy market.

TABLE OF CONTENT

Table Of Contents

List Of Figures

List Of Charts

Research Methodology

• Step 1: Project Initiation & Team Selection
• Step 2: Prepare Data Systems And Perform Secondary Research
• Step 3: Preparation For Interviews & Questionnaire Design
• Step 4: Performing Primary Research
• Step 5: Research Analysis: Establishing Baseline Estimates
• Step 6: Market Forecast And Analysis
• Step 7: Identify Strategic Opportunities
• Step 8: Final Review And Market Release
• Step 9: Customer Feedback And Market Monitoring

Impact Of Global Tariffs

Endoscopic Submucosal Dissection Knife Market

• 10.1 Executive Summary
  • 10.1.1 Global Endoscopic Submucosal Dissection Knife Market Overview
  • 10.1.2 Competitive Analysis
  • 10.1.3 Regions Included
• 10.2 Introduction
• 10.3 Market Analysis And Forecast
• 10.4 Drivers And Limiters
  • 10.4.1 Market Drivers
  • 10.4.2 Market Limiters
• 10.5 Competitive Market Share Analysis

Abbreviations

LIST OF CHARTS

• Chart 10-1: Endoscopic Submucosal Dissection Knife Market, Global, 2025 & 2032
• Chart 10-2: Endoscopic Submucosal Dissection Knife Procedures, Global, 2025
• Chart 10-3: Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032
• Chart 10-4: Leading Competitors, Endoscopic Submucosal Dissection Knife Market, Global, 2025

LIST OF FIGURES

• Figure 10-1: Endoscopic Submucosal Dissection Knife Regions Covered, Global (1 of 2)
• Figure 10-2: Endoscopic Submucosal Dissection Knife Regions Covered, Global (2 of 2)
• Figure 10-3: Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032
• Figure 10-4: Units Sold by Region, Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032
• Figure 10-5: Average Selling Price by Region, Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032 (US$)
• Figure 10-6: Market Value by Region, Endoscopic Submucosal Dissection Knife Market, Global, 2022 - 2032 (US$M)
• Figure 10-7: Leading Competitors, Endoscopic Submucosal Dissection Knife Market, Global, 2025