美國聚合物藥物研發外包市場規模、佔有率、趨勢分析報告：按工作流程、服務、治療類別、最終用途、細分市場預測，2025-2033

市場規模與趨勢：

預計 2024 年美國聚合物藥物發現外包市場規模將達到 9.686 億美元，預計 2025 年至 2033 年的複合年成長率為 9.20%。

由於製藥業加速向創新生技藥品轉變以及生技藥品產品線不斷擴大，市場正在經歷強勁成長，因為單株抗體、雙特異性抗體、融合蛋白和抗體藥物複合體（ADC）等大分子在治療各種疾病（包括癌症、自體免疫疾病和慢性疾病）方面的需求持續旺盛。

在美國，製藥和生技公司擴大轉向委外研發機構(CRO)，以加快藥物研發流程、降低成本並獲得專業知識。這些外包夥伴關係提供各種服務，包括先導化合物、候選藥物最佳化、生物學服務和臨床前開發，並正在朝向基於平台的整合式外包模式邁進。此外，對生技藥品（尤其是融合蛋白和工程抗體等新一代製劑）日益成長的需求，正促使公司將研發業務外包，以縮短週期並管理複雜性。

以精準篩檢、生物目標和體外功能分析為重點的外包可增強分子最佳化和早期可製造性評估。罕見疾病和個人化免疫療法等利基治療領域的興起進一步推動了對高度客製化藥物發現解決方案的需求。此外，透過單一合作夥伴網路整合發現、臨床前和早期開發活動的外包模式預計將在整個預估期內推動市場發展。在美國，對人工智慧標靶發現、微流體篩檢、低溫電子顯微鏡和雲端原生平台等技術進步的關注正在成為跨不同開發計劃的生物製藥藥物發現的戰略推動因素，進一步推動市場成長。

目錄

第1章調查方法與範圍

第2章執行摘要

第3章美國聚合物藥物發現外包市場變數、趨勢與範圍

• 市場展望
  • 母市場展望
  • 相關/支持市場展望
• 市場動態
  • 市場促進因素分析
  • 市場限制因素分析
• 技術格局
• 定價模式分析
• 市場分析工具
  • 波特五力分析
  • PESTEL 與 SWOT 分析

第4章美國聚合物藥物發現外包市場：工作流程評估與趨勢分析

• 美國聚合物藥物研發外包市場（依工作流程）：細分儀表板
• 美國聚合物藥物研發外包市場（依工作流程）：差異分析
• 按工作流程，2021-2033 年
• 目標識別與篩檢
• 目標檢驗和功能資訊科學
• 潛在客戶資格審查和候選人最佳化
• 臨床前開發
• 其他

第5章美國聚合物藥物發現外包市場：服務評估與趨勢分析

• 美國聚合物藥物研發外包市場（按服務）：細分儀表板
• 美國聚合物藥物研發外包市場（按服務）：變化分析
• 按服務分類，2021-2033 年
• 化學服務
• 生物服務

第6章美國聚合物藥物研發外包市場：治療藥物細分市場的估價與趨勢分析

• 美國聚合物藥物研發外包市場（依治療領域）：細分儀表板
• 美國聚合物藥物研發外包市場（依治療類別）：波動分析
• 2021-2033 年各治療類別藥物
• 呼吸系統
• 疼痛和麻醉
• 腫瘤學
• 眼科
• 血液學
• 心血管系統
• 內分泌
• 胃腸道
• 免疫調節
• 抗感染
• 中樞神經系統
• 皮膚科
• 泌尿生殖系統

第7章美國聚合物藥物發現外包市場：最終用途估計與趨勢分析

• 美國聚合物藥物研發外包市場（依最終用途）：細分儀表板
• 美國聚合物藥物研發外包市場（依最終用途）：差異分析
• 按應用，2021-2033 年
• 製藥和生物技術公司
• 學術機構

第8章 競爭態勢

• 市場參與企業分類
  • 市場領導者
  • 新興企業
• 2024 年公司市場佔有率/估值分析
• 公司簡介
  • Charles River Laboratories International, Inc.
  • Laboratory Corporation of America Holdings
  • Thermo Fisher Scientific, Inc.
  • GenScript Biotech Corporation
  • Syngene International Limited
  • Dalton Pharma Services
  • Eurofins Scientific SE
  • TCG Lifesciences Pvt Ltd.
  • Evotec SE
  • WuXi AppTec
  • Jubilant Biosys Limited
  • Pharmaron Beijing Co., Ltd.

第9章 主要建議

Market Size & Trends:

The U.S. large molecule drug discovery outsourcing market size was estimated at USD 968.60 million in 2024 and is projected to grow at a CAGR of 9.20% from 2025 to 2033. The market is experiencing robust growth, driven by the accelerating shift in the pharmaceutical industry towards innovative biologics and expanding pipeline biologics. Besides, large molecules, including monoclonal antibodies, bispecific, fusion proteins, and antibody-drug conjugates (ADCs), continue to witness rising demand to treat various diseases, including cancer, autoimmune disorders, and chronic conditions.

In the U.S., pharmaceutical and biotechnology companies are increasingly turning to contract research organizations (CROs) to accelerate the discovery process, lower costs, and gain access to specialized technologies. These outsourcing partnerships provide various services, including lead identification, candidate optimization, biology services, and preclinical development, with a shift toward integrated, platform-based outsourcing models. Moreover, rising demand for biologics, particularly next-generation formats such as fusion proteins and engineered antibodies, has led companies to outsource discovery tasks to reduce cycle times and manage complexity.

Outsourcing the company's focus on precision screening, target biology, and in vitro functional analysis enhances molecular optimization and early manufacturability assessments. The rise of niche therapeutic areas, such as rare diseases and personalized immunotherapies, further increases the need for highly customized discovery solutions. Besides, integrated outsourcing models that combine discovery, preclinical, and early development activities through a single partner network are expected to drive the market over the estimated period. With a focus on technological advancements in the U.S., including AI-driven target discovery, microfluidics-based screening, cryo-electron microscopy, and cloud-native platforms, outsourcing for extensive molecule drug discovery is becoming a strategic enabler of biologic drug discovery across diverse development programs, which further supports the market growth.

U.S. Large Molecule Drug Discovery Outsourcing Market Report Segmentation

This report forecasts revenue growth at the country level and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the U.S. large molecule drug discovery outsourcing market report based on workflow, service, therapeutics area, and end-use:

• Workflow Outlook (Revenue, USD Million, 2021 - 2033)
• Target Identification & Screening
• Target Validation & Functional Informatics
• Lead Identification & Candidate Optimization
• Preclinical Development
• Others
• Service Outlook (Revenue, USD Million, 2021 - 2033)
• Chemistry Services
• Biology Services
• Therapeutics Area Outlook (Revenue, USD Million, 2021 - 2033)
• Respiratory system
• Pain and Anesthesia
• Oncology
• Ophthalmology
• Hematology
• End-use Outlook (Revenue, USD Million, 2021 - 2033)
• Pharmaceutical & Biotechnology companies
• Academic Institutes

Table of Contents

Chapter 1. Research Methodology and Scope

• 1.1. Market Segmentation & Scope
• 1.2. Market Definitions
• 1.3. Research Methodology
• 1.4. Information Procurement
  • 1.4.1. Purchased Database
  • 1.4.2. GVR's Internal Database
  • 1.4.3. Secondary Sources
  • 1.4.4. Primary Research
• 1.5. Information Or Data Analysis
  • 1.5.1. Data Analysis Models
• 1.6. Market Formulation & Validation
• 1.7. Model Details
  • 1.7.1. Commodity Flow Analysis
  • 1.7.2. Parent Market Analysis
• 1.8. List Of Secondary Sources
• 1.9. List Of Abbreviations
• 1.10. Objectives

Chapter 2. Executive Summary

• 2.1. Market Outlook
• 2.2. Segment Outlook
• 2.3. Competitive Insights

Chapter 3. U.S. Large Molecule Drug Discovery Outsourcing Market Variables, Trends & Scope

• 3.1. Market Lineage Outlook
  • 3.1.1. Parent Market Outlook
  • 3.1.2. Related/Ancillary Market Outlook
• 3.2. Market Dynamics
  • 3.2.1. Market Driver Analysis
  • 3.2.2. Market Restraint Analysis
• 3.3. Technology Landscape
• 3.4. Pricing Model Analysis
• 3.5. Market Analysis Tools
  • 3.5.1. Porter's Five Force Analysis
  • 3.5.2. PESTEL by SWOT Analysis

Chapter 4. U.S. Large Molecule Drug Discovery Outsourcing Market: Workflow Estimates & Trend Analysis

• 4.1. U.S. Large Molecule Drug Discovery Outsourcing Market, By Workflow: Segment Dashboard
• 4.2. U.S. Large Molecule Drug Discovery Outsourcing Market, By Workflow: Movement Analysis
• 4.3. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Workflow, 2021-2033 (USD Million)
• 4.4. Target Identification & Screening
  • 4.4.1. Target Identification & Screening Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 4.5. Target Validation & Functional Informatics
  • 4.5.1. Target Validation & Functional Informatics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 4.6. Lead Identification & Candidate Optimization
  • 4.6.1. Lead Identification & Candidate Optimization Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 4.7. Preclinical Development
  • 4.7.1. Preclinical Development Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 4.8. Others
  • 4.8.1. Others Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 5. U.S. Large Molecule Drug Discovery Outsourcing Market: Service Estimates & Trend Analysis

• 5.1. U.S. Large Molecule Drug Discovery Outsourcing Market, By Service: Segment Dashboard
• 5.2. U.S. Large Molecule Drug Discovery Outsourcing Market, By Service: Movement Analysis
• 5.3. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Service, 2021-2033 (USD Million)
• 5.4. Chemistry Services
  • 5.4.1. Chemistry Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 5.5. Biology Services
  • 5.5.1. Biology Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 6. U.S. Large Molecule Drug Discovery Outsourcing Market: Therapeutics Area Estimates & Trend Analysis

• 6.1. U.S. Large Molecule Drug Discovery Outsourcing Market, By Therapeutics Area: Segment Dashboard
• 6.2. U.S. Large Molecule Drug Discovery Outsourcing Market, By Therapeutics Area: Movement Analysis
• 6.3. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By Therapeutics Area, 2021-2033 (USD Million)
• 6.4. Respiratory system
  • 6.4.1. Respiratory System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.5. Pain and Anesthesia
  • 6.5.1. Pain and Anesthesia Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.6. Oncology
  • 6.6.1. Oncology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.7. Ophthalmology
  • 6.7.1. Ophthalmology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.8. Hematology
  • 6.8.1. Hematology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.9. Cardiovascular
  • 6.9.1. Cardiovascular Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.10. Endocrine
  • 6.10.1. Endocrine Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.11. Gastrointestinal
  • 6.11.1. Gastrointestinal Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.12. Immunomodulation
  • 6.12.1. Immunomodulation Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.13. Anti-infective
  • 6.13.1. Anti-infective Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.14. Central Nervous System
  • 6.14.1. Central Nervous System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.15. Dermatology
  • 6.15.1. Dermatology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 6.16. Genitourinary System
  • 6.16.1. Genitourinary System Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 7. U.S. Large Molecule Drug Discovery Outsourcing Market: End Use Estimates & Trend Analysis

• 7.1. U.S. Large Molecule Drug Discovery Outsourcing Market, By End Use: Segment Dashboard
• 7.2. U.S. Large Molecule Drug Discovery Outsourcing Market, By End Use: Movement Analysis
• 7.3. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates & Forecasts, By End Use, 2021-2033 (USD Million)
• 7.4. Pharmaceutical & Biotechnology companies
  • 7.4.1. Pharmaceutical & Biotechnology companies Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• 7.5. Academic Institutes
  • 7.5.1. Academic Institutes Market Estimates and Forecasts, 2021 - 2033 (USD Million)

Chapter 8. Competitive Landscape

• 8.1. Market Participant Categorization
  • 8.1.1. Market Leaders
  • 8.1.2. Emerging Players
• 8.2. Company Market Share/Assessment Analysis, 2024
• 8.3. Company Profiles
  • 8.3.1. Charles River Laboratories International, Inc.
    • 8.3.1.1. Company Overview
    • 8.3.1.2. Financial Performance
    • 8.3.1.3. Service Benchmarking
    • 8.3.1.4. Strategic Initiatives
  • 8.3.2. Laboratory Corporation of America Holdings
    • 8.3.2.1. Company Overview
    • 8.3.2.2. Financial Performance
    • 8.3.2.3. Service Benchmarking
    • 8.3.2.4. Strategic Initiatives
  • 8.3.3. Thermo Fisher Scientific, Inc.
    • 8.3.3.1. Company Overview
    • 8.3.3.2. Financial Performance
    • 8.3.3.3. Service Benchmarking
    • 8.3.3.4. Strategic Initiatives
  • 8.3.4. GenScript Biotech Corporation
    • 8.3.4.1. Company Overview
    • 8.3.4.2. Financial Performance
    • 8.3.4.3. Service Benchmarking
    • 8.3.4.4. Strategic Initiatives
  • 8.3.5. Syngene International Limited
    • 8.3.5.1. Company Overview
    • 8.3.5.2. Financial Performance
    • 8.3.5.3. Service Benchmarking
    • 8.3.5.4. Strategic Initiatives
  • 8.3.6. Dalton Pharma Services
    • 8.3.6.1. Company Overview
    • 8.3.6.2. Financial Performance
    • 8.3.6.3. Service Benchmarking
    • 8.3.6.4. Strategic Initiatives
  • 8.3.7. Eurofins Scientific SE
    • 8.3.7.1. Company Overview
    • 8.3.7.2. Financial Performance
    • 8.3.7.3. Service Benchmarking
    • 8.3.7.4. Strategic Initiatives
  • 8.3.8. TCG Lifesciences Pvt Ltd.
    • 8.3.8.1. Company Overview
    • 8.3.8.2. Financial Performance
    • 8.3.8.3. Service Benchmarking
    • 8.3.8.4. Strategic Initiatives
  • 8.3.9. Evotec SE
    • 8.3.9.1. Company Overview
    • 8.3.9.2. Financial Performance
    • 8.3.9.3. Service Benchmarking
    • 8.3.9.4. Strategic Initiatives
  • 8.3.10. WuXi AppTec
    • 8.3.10.1. Company Overview
    • 8.3.10.2. Financial Performance
    • 8.3.10.3. Service Benchmarking
    • 8.3.10.4. Strategic Initiatives
  • 8.3.11. Jubilant Biosys Limited
    • 8.3.11.1. Company Overview
    • 8.3.11.2. Financial Performance
    • 8.3.11.3. Service Benchmarking
    • 8.3.11.4. Strategic Initiatives
  • 8.3.12. Pharmaron Beijing Co., Ltd.
    • 8.3.12.1. Company Overview
    • 8.3.12.2. Financial Performance
    • 8.3.12.3. Service Benchmarking
    • 8.3.12.4. Strategic Initiatives

Chapter 9 Key Recommendations

List of Tables

• Table 1. List of Tables
• Table 2. List of Secondary Sources
• Table 3. List of Abbreviations
• Table 4. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Workflow, 2021 - 2033 (USD Million)
• Table 5. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Service, 2021 - 2033 (USD Million)
• Table 6. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by Therapeutics Area, 2021 - 2033 (USD Million)
• Table 7. U.S. Large Molecule Drug Discovery Outsourcing Market Estimates and Forecasts, by End Use, 2021 - 2033 (USD Million)

List of Figures

• Fig. 1 Market research process
• Fig. 2 Information procurement
• Fig. 3 Primary research pattern
• Fig. 4 Market research approaches
• Fig. 5 Market formulation & validation
• Fig. 6 Commodity flow analysis
• Fig. 7 Value-chain-based sizing & forecasting
• Fig. 8 QFD model sizing & forecasting
• Fig. 9 Bottom-up approach
• Fig. 10 Market snapshot
• Fig. 11 Segment snapshot 1
• Fig. 12 Segment snapshot 2
• Fig. 13 Competitive landscape snapshot
• Fig. 14 Parent market outlook, 2024 (USD Billion)
• Fig. 15 Ancillary market outlook, 2024 (USD Billion)
• Fig. 16 U.S. Large Molecule Drug Discovery Outsourcing Market Dynamics
• Fig. 17 Porter's five forces analysis
• Fig. 18 PESTEL analysis
• Fig. 19 U.S. Large Molecule Drug Discovery Outsourcing Market: Workflow outlook and key takeaways
• Fig. 20 U.S. Large Molecule Drug Discovery Outsourcing Market: Workflow movement analysis
• Fig. 21 Target Identification & Screening Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 22 Target Validation & Functional Informatics Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 23 Lead Identification & Candidate Optimization Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 24 Preclinical Development Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 25 Other Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 26 U.S. Large Molecule Drug Discovery Outsourcing Market: Service outlook and key takeaways
• Fig. 27 U.S. Large Molecule Drug Discovery Outsourcing Market: Service movement analysis
• Fig. 28 Chemistry Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 29 Biology Services Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 30 U.S. Large Molecule Drug Discovery Outsourcing Market: Therapeutics Area outlook and key takeaways
• Fig. 31 U.S. Large Molecule Drug Discovery Outsourcing Market: Therapeutics Area movement analysis
• Fig. 32 Respiratory system Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 33 Pain and Anesthesia Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 34 Oncology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 35 Ophthalmology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 36 Hematology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 37 Cardiovascular Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 38 Endocrine Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 39 Gastrointestinal Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 40 Immunomodulation Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 41 Anti-infective Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 42 Central Nervous System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 43 Dermatology Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 44 Genitourinary System Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 45 U.S. Large Molecule Drug Discovery Outsourcing Market: End Use outlook and key takeaways
• Fig. 46 U.S. Large Molecule Drug Discovery Outsourcing Market: End Use movement analysis
• Fig. 47 Pharmaceutical & Biotechnology companies Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 48 Academic Institutes Market Estimates and Forecasts, 2021 - 2033 (USD Million)
• Fig. 49 Key company categorization
• Fig. 50 Service heat map analysis
• Fig. 51 Strategic framework