Product Code: GVR-3-68038-592-2
Upstream Bioprocessing Market Growth & Trends:
The global upstream bioprocessing market size is expected to reach USD 59.1 billion by 2030, expanding at a CAGR of 16.6% from 2023 to 2030, according to a new report by Grand View Research, Inc.. Commercial success and wide acceptance of biopharmaceuticals have provided lucrative growth avenues to several in house as well as contract manufacturing biopharmaceutical companies. Furthermore, a confluence of factors, such as high demand for biosimilars and biologics, launch of improved cost-effective technologies, and growing acceptance of single-use systems have driven the revenue performance of the market.
Start-ups and new market entrants often face budget constraints while establishing new biomanufacturing plants. Thus, these entities expand their biotherapeutics portfolio by outsourcing the production process to contract services, thereby aiding in revenue growth for upstream bioprocessing services.
Continuous upstream bioprocessing has greatly benefited the bioprocessing industry. Rising implementation of methods, such as acoustic wave technology and continuous centrifugation, for clarification of bioreactor cultures tends to minimize the clarification burden. This, in turn, increases the cell-culture densities, consequently resulting in efficient upstream processes.
Ongoing advancements in cell line productivity with respect to protein expression and clone screening are expected to result in the fastest CAGR of cell culture products over the forecast period. Cell culture is considered as the most challenging and crucial step in upstream bioprocessing, and thus demands more attention with respect to technological intricacies, resulting in the largest share in the upstream bioprocessing market.
Factors such as multi-use systems incur one-time investment, are applicable for larger bioprocessing volumes and maintain the pH and oxygen accurately resulting in high usage rate of these systems. However, a paradigm shift from conventional stainless-steel bioreactors to single-use bioreactor systems has attributed to the lucrative growth of the single-use segment.
Key market players are adopting strategic initiatives, such as novel product developments, mutually beneficial partnerships, agreements, and geographical expansion to reinforce their market presence. For instance, in February 2019, Danaher Corporation signed an agreement to acquire the Biopharma business of GE Life Sciences. The acquisition broadened Danaher's market presence with the addition of GE Biopharma's cell culture media, single-use technologies, development instrumentation, and consumables to its existing portfolio.
Upstream Bioprocessing Market Report Highlights:
- High availability of bioreactors and continuous launches of single-use bioreactors by the key market players can be attributed to the remarkable revenue share of the bioreactors segment
- Presence of well-established biopharmaceutical manufacturing firms capable of performing in-house bioproduction has led to the maximum revenue share of this segment
- Outsourced mode of upstream bioprocessing is anticipated to witness the fastest CAGR over the forecast period, owing to increase in investments and expansion of manufacturing capabilities through the integration of single-use systems in the plants by CMOs
- North America dominated the global upstream bioprocessing market as a result of the continuous innovations in biotechnology and rising preferences for biopharmaceuticals in the region. Moreover, the presence of substantial in-house biopharmaceutical manufacturers coupled with numerous investments in the U.S. biologics market has driven the growth
- Asia Pacific is poised to witness the fastest CAGR over the forecast period due to growing awareness about the rapid analytical methods that can be used for in-process control during the upstream workflows
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.1.1. Product
- 1.1.2. Workflow
- 1.1.3. Use Type
- 1.1.4. Mode
- 1.1.5. Regional scope
- 1.1.6. Estimates and forecast timeline
- 1.2. Research Methodology
- 1.3. Information Procurement
- 1.3.1. Purchased database
- 1.3.2. GVR's internal database
- 1.3.3. Secondary sources
- 1.3.4. Primary research
- 1.3.5. Details of primary research
- 1.4. Information or Data Analysis
- 1.5. Market Formulation & Validation
- 1.6. Model Details
- 1.7. List of Secondary Sources
- 1.8. List of Primary Sources
- 1.9. Objectives
Chapter 2. Executive Summary
- 2.1. Market Outlook
- 2.2. Segment Outlook
- 2.2.1. Product outlook
- 2.2.2. Workflow outlook
- 2.2.3. Use type outlook
- 2.2.4. Mode outlook
- 2.2.5. Regional outlook
- 2.3. Competitive Insights
Chapter 3. Upstream Bioprocessing Market Variables, Trends & Scope
- 3.1. Market Lineage Outlook
- 3.1.1. Parent market outlook
- 3.1.2. Related/ancillary market outlook
- 3.2. Market Dynamics
- 3.2.1. Market driver analysis
- 3.2.2. Market restraint analysis
- 3.3. Upstream Bioprocessing Market Analysis Tools
- 3.3.1. Industry Analysis - Porter's
- 3.3.1.1. Supplier power
- 3.3.1.2. Buyer power
- 3.3.1.3. Substitution threat
- 3.3.1.4. Threat of new entrant
- 3.3.1.5. Competitive rivalry
- 3.3.2. PESTEL Analysis
- 3.3.2.1. Political landscape
- 3.3.2.2. Technological landscape
- 3.3.2.3. Economic landscape
Chapter 4. Upstream Bioprocessing: Product Estimates & Trend Analysis
- 4.1. Upstream Bioprocessing Market: Key Takeaways
- 4.2. Upstream Bioprocessing Market: Movement & Market Share Analysis, 2022 & 2030
- 4.3. Bioreactors/Fermenters
- 4.3.1. Bioreactors/Fermenters market estimates and forecasts, 2018 to 2030 (USD Billion)
- 4.4. Cell Culture Products
- 4.4.1. Cell culture products market estimates and forecasts, 2018 to 2030 (USD Billion)
- 4.5. Filters
- 4.5.1. Filters market estimates and forecasts, 2018 to 2030 (USD Billion)
- 4.6. Bioreactors Accessories
- 4.6.1. Bioreactors accessories market estimates and forecasts, 2018 to 2030 (USD Billion)
- 4.7. Bags & Containers
- 4.7.1. Bags & containers market estimates and forecasts, 2018 to 2030 (USD Billion)
- 4.8. Others
- 4.8.1. Others market estimates and forecasts, 2018 to 2030 (USD Billion)
Chapter 5. Upstream Bioprocessing: Workflow Estimates & Trend Analysis
- 5.1. Upstream Bioprocessing Market: Key Takeaways
- 5.2. Upstream Bioprocessing Market: Movement & Market Share Analysis, 2022 & 2030
- 5.3. Media Preparation
- 5.3.1. Media preparation market estimates and forecasts, 2018 to 2030 (USD Billion)
- 5.4. Cell Culture
- 5.4.1. Cell culture market estimates and forecasts, 2018 to 2030 (USD Billion)
- 5.5. Cell Separation
- 5.5.1. Cell separation market estimates and forecasts, 2018 to 2030 (USD Billion)
Chapter 6. Upstream Bioprocessing: Use Type Estimates & Trend Analysis
- 6.1. Upstream Bioprocessing Market: Key Takeaways
- 6.2. Upstream Bioprocessing Market: Movement & Market Share Analysis, 2022 & 2030
- 6.3. Multi-Use
- 6.3.1. Multi-use market estimates and forecasts, 2018 to 2030 (USD Billion)
- 6.4. Single-Use
- 6.4.1. Single-use market estimates and forecasts, 2018 to 2030 (USD Billion)
Chapter 7. Upstream Bioprocessing: Mode Estimates & Trend Analysis
- 7.1. Upstream Bioprocessing Market: Key Takeaways
- 7.2. Upstream Bioprocessing Market: Movement & Market Share Analysis, 2022 & 2030
- 7.3. In-House
- 7.3.1. In-house market estimates and forecasts, 2018 to 2030 (USD Billion)
- 7.4. Outsourced
- 7.4.1. Outsourced market estimates and forecasts, 2018 to 2030 (USD Billion)
Chapter 8. Upstream Bioprocessing Market: Regional Estimates & Trend Analysis
- 8.1. Regional Outlook
- 8.2. Upstream Bioprocessing Market by Region: Key Takeaways
- 8.3. North America
- 8.3.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.3.2. U.S.
- 8.3.2.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.3.3. Canada
- 8.3.3.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.4. Europe
- 8.4.1. UK
- 8.4.1.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.4.2. Germany
- 8.4.2.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.4.3. France
- 8.4.3.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.4.4. Italy
- 8.4.4.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.4.5. Spain
- 8.4.5.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.4.6. Sweden
- 8.4.6.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.4.7. Norway
- 8.4.7.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.4.8. Denmark
- 8.4.8.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.5. Asia Pacific
- 8.5.1. Japan
- 8.5.1.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.5.2. China
- 8.5.2.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.5.3. India
- 8.5.3.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.5.4. Australia
- 8.5.4.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.5.5. Thailand
- 8.5.5.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.5.6. South Korea
- 8.5.6.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.6. Latin America
- 8.6.1. Brazil
- 8.6.1.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.6.2. Mexico
- 8.6.2.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.6.3. Argentina
- 8.6.3.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.7. MEA
- 8.7.1. South Africa
- 8.7.1.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.7.2. Saudi Arabia
- 8.7.2.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.7.3. UAE
- 8.7.3.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
- 8.7.4. Kuwait
- 8.7.4.1. Market estimates and forecasts, 2018 - 2030 (Revenue, USD Billion)
Chapter 9. Competitive Landscape
- 9.1. Recent Developments & Impact Analysis, By Key Market Participants
- 9.2. Market Participant Categorization
- 9.2.1. GE HealthCare
- 9.2.1.1. Company overview
- 9.2.1.2. Financial performance
- 9.2.1.3. Product benchmarking
- 9.2.1.4. Strategic initiatives
- 9.2.2. Thermo Fisher Scientific Inc.
- 9.2.2.1. Company overview
- 9.2.2.2. Financial performance
- 9.2.2.3. Product benchmarking
- 9.2.2.4. Strategic initiatives
- 9.2.3. Merck KGaA
- 9.2.3.1. Company overview
- 9.2.3.2. Financial performance
- 9.2.3.3. Product benchmarking
- 9.2.3.4. Strategic initiatives
- 9.2.4. Corning, Inc.
- 9.2.4.1. Company overview
- 9.2.4.2. Financial performance
- 9.2.4.3. Product benchmarking
- 9.2.4.4. Strategic initiatives
- 9.2.5. Sartorius AG
- 9.2.5.1. Company overview
- 9.2.5.2. Financial performance
- 9.2.5.3. Product benchmarking
- 9.2.5.4. Strategic initiatives
- 9.2.6. Eppendorf AG
- 9.2.6.1. Company overview
- 9.2.6.2. Financial performance
- 9.2.6.3. Product benchmarking
- 9.2.6.4. Strategic initiatives
- 9.2.7. Danaher
- 9.2.7.1. Company overview
- 9.2.7.2. Financial performance
- 9.2.7.3. Product benchmarking
- 9.2.7.4. Strategic initiatives
- 9.2.8. Boehringer Ingelheim GmbH
- 9.2.8.1. Company overview
- 9.2.8.2. Financial performance
- 9.2.8.3. Product benchmarking
- 9.2.8.4. Strategic initiatives
- 9.2.9. Applikon Biotechnology
- 9.2.9.1. Company overview
- 9.2.9.2. Financial performance
- 9.2.9.3. Product benchmarking
- 9.2.9.4. Strategic initiatives
- 9.2.10. PBS Biotech, Inc.
- 9.2.10.1. Company overview
- 9.2.10.2. Financial performance
- 9.2.10.3. Product benchmarking
- 9.2.10.4. Strategic initiatives
- 9.2.11. Lonza
- 9.2.11.1. Company overview
- 9.2.11.2. Financial performance
- 9.2.11.3. Product benchmarking
- 9.2.11.4. Strategic initiatives
- 9.2.12. CellGenix GmbH
- 9.2.12.1. Company overview
- 9.2.12.2. Financial performance
- 9.2.12.3. Product benchmarking
- 9.2.12.4. Strategic initiatives
- 9.2.13. Samsung BioLogics
- 9.2.13.1. Company overview
- 9.2.13.2. Financial performance
- 9.2.13.3. Product benchmarking
- 9.2.13.4. Strategic initiatives
- 9.2.14. AGC Inc.
- 9.2.14.1. Company overview
- 9.2.14.2. Financial performance
- 9.2.14.3. Product benchmarking
- 9.2.14.4. Strategic initiatives
- 9.2.15. VWR International, LLC
- 9.2.15.1. Company overview
- 9.2.15.2. Financial performance
- 9.2.15.3. Product benchmarking
- 9.2.15.4. Strategic initiatives