Product Code: GVR-4-68040-022-4
mRNA Synthesis Raw Materials Market Growth & Trends:
The global mRNA synthesis raw materials market size is projected to reach USD 3.3 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 2.1% from 2023 to 2030. The major factors driving the market growth include growing academic and industrial interest in mRNA technology, the advantages of mRNA vaccines, and increasing funding for research. In addition, the increasing therapeutic applications of RNA technology are projected to offer lucrative opportunities for the mRNA synthesis raw materials market during the forecast period.
The COVID-19 pandemic has increased the demand for mRNA synthesis raw materials for developing an efficient vaccine to battle infectious diseases. mRNA vaccines are a safe and efficient method for preventing COVID-19. In addition, the advantages associated with the mRNA COVID-19 vaccines have sparked the attention of pharmaceutical businesses in delivering vaccines swiftly across the globe. For instance, the National Institute of Allergy and Infectious Diseases and Moderna, Inc. mutually developed the mRNA-1273 (NIAID) in March 2020. As a result, the usage of mRNA vaccines increased significantly during the COVID-19 pandemic.
Furthermore, many major pharmaceutical firms have started working on mRNA-based therapeutics, including Novartis, Alexion, AstraZeneca, Pfizer, Sanofi Pasteur, and Shire. For instance, in January 2022, according to a development and option agreement between Pfizer Inc. and Acuitas Therapeutics, Pfizer will have the option to license Acuitas' LNP technology for up to 10 targets for the development of mRNA therapeutics & vaccines. Therefore, the adoption rate of mRNA synthesis raw materials has increased among pharma & biotech companies, which further fuels the market growth.
Moreover, due to the temporary nature of mRNA translation and lack of integration of the foreign material into the cell's genome, the resulting cellular therapeutic product has a number of benefits over the one obtained by a more conventional approach. Some of the advantages include easier production under acceptable manufacturing procedures, reduced cytotoxicity from on-target off-tumor effects, and better clinical validation and regulatory treatment. Thus, such advantages are expected to increase the demand for mRNA therapeutics and further boost market growth.
Additionally, regarding the treatment and prevention of several diseases, mRNA-based technologies have been proven to be incredibly promising. Tremendous advances in technology and scientific study over the past ten years have made mRNA a feasible therapeutic option, eliminating some of the problems with its use, such as its brief half-life and innate immunogenicity. For instance, as mRNA technology advances, its fusion with new adoptive immunotherapies may result in safer and more efficient methods, such as the creation of cutting-edge chimeric antigen receptor T-cells. Therefore, advancements in mRNA technology are projected to open new avenues for market growth.
However, the high cost of raw materials may impede the market during the study period. For instance, the purchase price of raw materials, such as CleanCap AG, accounts for around 45% of the total raw material costs incurred while producing both vaccines. In addition, the regulatory framework pertaining to approval processes has always been the most critical restraining factor in the biotechnology, pharmaceutical, and medical technology industry. The absence of effective regulatory framework/guidelines for the therapeutic sector in developing countries such as China and India, where the mRNA synthesis raw materials market holds great growth potential due to the presence of a large patient base, is anticipated to impede the market growth in the coming years.
mRNA Synthesis Raw Materials Market Report Highlights:
- The capping agents segment held the largest share of 40.6% in 2022 owing to the advancements in the capping technology and their applications in the biopharma industry and research
- By application, the vaccine production segment captured the highest share of 85.30% in 2022. This can be attributed to the rapid production of mRNA vaccines compared to the conventional vaccines that use cell-culture-based production routes, which are often prone to failure
- North America held the highest revenue share of 35.5% in 2022, due to the presence of key players, the availability of an established commercial infrastructure for biotechnology and pharmaceutical companies, and high research and development investments in the region
- By end-user, the biopharmaceutical and pharmaceutical companies segment dominated the market in 2022 due to the increasing investments in the biopharmaceutical sector and the rising pipeline, which has boosted the need for mRNA synthesis raw materials
Table of Contents
Chapter 1 Methodology and Scope
- 1.1 Research Methodology
- 1.2 Research Assumptions
- 1.2.1 Estimates And Forecast Timeline
- 1.3 Information Procurement
- 1.3.1 Purchased Database
- 1.3.2 Gvr's Internal Database
- 1.3.3 Secondary Sources
- 1.3.4 Primary Research
- 1.4 Information Or Data Analysis
- 1.4.1 Data Analysis Models
- 1.5 Market Formulation & Validation
Chapter 2 Executive Summary
- 2.1 Market Snapshot
- 2.2 Segment Snapshot
- 2.3 Competitive Landscape Snapshot
Chapter 3 Market Variables, Trends, & Scope
- 3.1 Parent Market Analysis
- 3.2 Market Dynamics
- 3.2.1 Market Driver Analysis
- 3.2.1.1 Growing Academic And Industrial Interest In mRNA Technology
- 3.2.1.2 Advantages Of mRNA Vaccines
- 3.2.1.3 Increasing Funding For mRNA Research
- 3.2.2 Market Restraint Analysis
- 3.2.2.1 Nonexistence Of Effective Government Regulations For mRNA - Based Product Approvals
- 3.2.2.2 High Cost Of mRNA Synthesis Raw Materials
- 3.2.3 Market Challange Analysis
- 3.2.3.1 Lack Of Long - Lasting And Affordable Manufacturing Processes
- 3.3 Penetration &Growth Prospect Mapping
- 3.4 mRNA Synthesis Raw Materials Market - Porter's Analysis
- 3.5 mRNA Synthesis Raw Materials Market - Swot Analysis
- 3.6 Covid - 19 Impact Analysis
Chapter 4 Type Business Analysis
- 4.1 mRNA Synthesis Raw Materials Market - Type Movement Analysis
- 4.2 Capping Agents
- 4.2.1 Global Capping Agents Market, 2018 - 2030 (USD Million)
- 4.3 Nucleotides
- 4.3.1 Global Nucleotides Market, 2018 - 2030 (USD Million)
- 4.4 Plasmid Dna
- 4.4.1 Global Plasmid Dna Market, 2018 - 2030 (USD Million)
- 4.5 Others
- 4.5.1 Global Other Types Market, 2018 - 2030 (USD Million)
Chapter 5 Application Business Analysis
- 5.1 mRNA Synthesis Raw Materials Market - Application Movement Analysis
- 5.2 Therapeutics Production
- 5.2.1 Global Therapeutics Production Market, 2018 - 2030 (USD Million)
- 5.3 Vaccine Production
- 5.3.1 Global Vaccine Production Market, 2018 - 2030 (USD Million)
- 5.4 Others
- 5.4.1 Global Other Applications Market, 2018 - 2030 (USD Million)
Chapter 6 End - User Business Analysis
- 6.1 mRNA Synthesis Raw Materials Market - End User Movement Analysis
- 6.2 Biopharmaceutical & Pharmaceutical Companies
- 6.2.1 Global Biopharmaceutical & Pharmaceutical Companies, 2018 - 2030 (USD Million)
- 6.3 Cros & Cmos
- 6.3.1 Global Cros & Cmos, 2018 - 2030 (USD Million)
- 6.4 Academic And Research Institutions
- 6.4.1 Global Academic And Research Institutions, 2018 - 2030 (USD Million)
Chapter 7 Regional Business Analysis
- 7.1 mRNA Synthesis Raw Materials Market: Regional Movement Analysis
- 7.2 North America
- 7.2.1 Swot Analysis
- 7.2.1.1 North America mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.2.2 U.S.
- 7.2.2.1 Key Country Dynamics
- 7.2.2.2 Competitive Scenario
- 7.2.2.3 Regulatory Framework
- 7.2.2.4 U.S. mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.2.3 Canada
- 7.2.3.1 Key country dynamics
- 7.2.3.2 Competitive scenario
- 7.2.3.3 Regulatory framework
- 7.2.3.4 Canada mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
- 7.3 Europe
- 7.3.1 Swot Analysis
- 7.3.1.1 Europe mRNA Synthesis Raw Materials Market Estimates And Forecast, 2018 - 2030 (USD Million)
- 7.3.2 Germany
- 7.3.2.1 Key Country Dynamics
- 7.3.2.2 Competitive Scenario
- 7.3.2.3 Regulatory Framework
- 7.3.2.4 Germany mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.3.3 U.K.
- 7.3.3.1 Key Country Dynamics
- 7.3.3.2 Competitive Scenario
- 7.3.3.3 Regulatory Framework
- 7.3.3.4 Uk mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.3.4 France
- 7.3.4.1 Key Country Dynamics
- 7.3.4.2 Competitive Scenario
- 7.3.4.3 Regulatory Framework
- 7.3.4.4 France mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.3.5 Italy
- 7.3.5.1 Key Country Dynamics
- 7.3.5.2 Competitive Scenario
- 7.3.5.3 Regulatory Framework
- 7.3.5.5 Italy mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.3.6 Spain
- 7.3.6.1 Key Country Dynamics
- 7.3.6.2 Competitive Scenario
- 7.3.6.3 Regulatory Framework
- 7.3.6.4 Spain mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.3.7 Denmark
- 7.3.7.1 Key Country Dynamics
- 7.3.7.2 Competitive Scenario
- 7.3.7.3 Regulatory Framework
- 7.3.7.4 Denmark mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.3.8 Sweden
- 7.3.8.1 Key Country Dynamics
- 7.3.8.2 Competitive Scenario
- 7.3.8.3 Regulatory Framework
- 7.3.8.4 Sweden mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.3.9 Norway
- 7.3.9.1 Key country dynamics
- 7.3.9.2 Competitive scenario
- 7.3.9.3 Regulatory framework
- 7.3.9.4 Norway mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
- 7.4 Asia Pacific
- 7.4.1 Swot Analysis
- 7.4.1.1 Asia Pacific mRNA Synthesis Raw Materials, 2018 - 2030 (USD Million)
- 7.4.2 Japan
- 7.4.2.1 Key Country Dynamics
- 7.4.2.2 Competitive Scenario
- 7.4.2.3 Regulatory Framework
- 7.4.2.4 Japan mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.4.3 China
- 7.4.3.1 Key Country Dynamics
- 7.4.3.2 Competitive Scenario
- 7.4.3.3 Regulatory Framework
- 7.4.3.4 China mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.4.4 India
- 7.4.4.1 Key Country Dynamics
- 7.4.4.2 Competitive Scenario
- 7.4.4.3 Regulatory Framework
- 7.4.4.4 India mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.4.5 Australia
- 7.4.5.1 Key Country Dynamics
- 7.4.5.2 Competitive Scenario
- 7.4.5.3 Regulatory Framework
- 7.4.5.4 Australia mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.4.6 South Korea
- 7.4.6.1 Key Country Dynamics
- 7.4.6.2 Competitive Scenario
- 7.4.6.3 Regulatory Framework
- 7.4.6.4 South Korea mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.4.7 Thailand
- 7.4.7.1 Key country dynamics
- 7.4.7.2 Competitive scenario
- 7.4.7.3 Regulatory framework
- 7.4.7.4 Thailand mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
- 7.5 Latin America
- 7.5.1 Swot Analysis
- 7.5.1.1 Latin America mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.5.2 Brazil
- 7.5.2.1 Key Country Dynamics
- 7.5.2.2 Competitive Scenario
- 7.5.2.3 Regulatory Framework
- 7.5.2.4 Brazil mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.5.3 Mexico
- 7.5.3.1 Key Country Dynamics
- 7.5.3.2 Competitive Scenario
- 7.5.3.3 Regulatory Framework
- 7.5.3.4 Mexico mRNA Synthesis Raw Materials Market, 2018 - 2030 (USD Million)
- 7.5.4 Argentina
- 7.5.4.1 Key country dynamics
- 7.5.4.2 Competitive scenario
- 7.5.4.3 Regulatory framework
- 7.5.4.4 Argentina mRNA synthesis raw materials market, 2018 - 2030 (USD Million)
- 7.6 Middle East & Africa
- 7.6.1 Swot Analysis
- 7.6.1.1 Mea mRNA Synthesis Raw Materials Market Estimates And Forecast, 2018 - 2030 (USD Million)
- 7.6.2 South Africa
- 7.6.2.1 Key country dynamics
- 7.6.2.2 Competitive scenario
- 7.6.2.3 Regulatory framework
- 7.6.2.4 South Africa mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
- 7.6.3 Saudi Arabia
- 7.6.3.1 Key country dynamics
- 7.6.3.2 Competitive scenario
- 7.6.3.3 Regulatory framework
- 7.6.3.4 Saudi Arabia mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
- 7.6.4 UAE
- 7.6.4.1 Key country dynamics
- 7.6.4.2 Competitive scenario
- 7.6.4.3 Regulatory framework
- 7.6.4.4 UAE mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
- 7.6.5 KUWAIT
- 7.6.5.1 Key country dynamics
- 7.6.5.2 Competitive scenario
- 7.6.5.3 Regulatory framework
- 7.6.5.4 Kuwait mRNA synthesis raw materials market estimates and forecast, 2018 - 2030 (USD Million)
Chapter 8 Competitive Landscape
- 8.1 Participant's Overview
- 8.1.1 F. Hoffmann - La Roche Ltd.
- 8.1.2 Jena Bioscience Gmbh
- 8.1.3 Merck KGaA
- 8.1.4 Yeasen Biotechnology (Shanghai) Co.,Ltd.
- 8.1.5 BOC Sciences
- 8.1.6 Thermo Fisher Scientific, Inc.
- 8.1.7 Maravai Lifesciences
- 8.1.8 New England Biolabs
- 8.1.9 Creative Biogene
- 8.1.10 Hongene
- 8.2 Financial Performance
- 8.3 Participant Categorization
- 8.3.1 Market Leaders
- 8.3.1.1 mRNA Synthesis Raw Materials Market Share Analysis, 2022
- 8.3.2 Strategy Mapping
- 8.3.2.1 Expansion
- 8.3.2.2 Acquisition
- 8.3.2.3 Collaborations
- 8.3.2.4 Product/service launch
- 8.3.2.5 Partnerships
- 8.3.2.6 Others