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市場調查報告書
商品編碼
1875912
全球髖置換術植入市場Hip Resurfacing Implants |
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預計到 2030 年,全球髖關節表面置換植入市場規模將達到 2.648 億美元。
2024年全球髖關節表面置換植入市場規模估計為2.235億美元,預計到2030年將達到2.648億美元,在分析期(2024-2030年)內複合年成長率(CAGR)為2.9%。本報告分析的混合合金材料細分市場預計將以3.7%的複合年成長率成長,並在分析期結束時達到1.289億美元。鈷鉻合金材料細分市場預計在分析期間將以2.4%的複合年成長率成長。
美國市場規模估計為6,070萬美元,而中國市場預計將以2.8%的複合年成長率成長。
據估計,2024年美國髖關節表面置換植入市場規模將達6,070萬美元。作為世界第二大經濟體,中國預計到2030年市場規模將達到4,240萬美元,在2024年至2030年的分析期間內,年複合成長率(CAGR)為2.8%。其他值得關注的區域市場分析包括日本和加拿大,預計在分析期間內,這兩個國家的年複合成長率分別為2.7%和2.4%。在歐洲,德國預計將以約3.1%的年複合成長率成長。
全球髖關節表面置換植入市場—主要趨勢與促進因素概述
髖關節置換術是未來活躍病患整形外科治療計畫的發展方向嗎?
髖關節表面置換植入正在改變整形外科手術的格局,但為什麼它會成為髖關節退化性疾病患者的重要選擇呢?髖置換術是一種保留骨骼的替代傳統全髖關節置換術(THR)的方法,主要適用於年輕、活躍的患者。 THR 需要切除整個股骨頭並用人工關節替換,而髖置換術術則是用金屬植入再形成並覆蓋股骨頭,髀臼(髖關節窩)也包含金屬部件。這使得患者能夠保留更多自身骨骼結構,提高穩定性,並允許手術後進行更多體育活動。
髖置換術的優點在於其耐用性和骨保留優勢,特別適用於那些可能壽命超過傳統髖植入體壽命、需要重新置換手術的年輕患者。透過保留更多患者自身骨骼,並使關節負荷分佈更加自然,髖置換術能夠改善活動能力和功能,同時降低脫位風險。對於活躍人群而言,髖置換術植入能夠帶來更自然的活動範圍,使其成為術後希望保持積極生活方式的患者的理想選擇。隨著全球人口老化以及對更耐用、更持久的整形外科治療方法需求的不斷成長,髖關節置換術正逐漸成為治療髖關節骨性關節炎和其他退化性髖關節疾病的重要選擇。
科技如何推動髖置換術植入的發展?
技術進步顯著改善了髖關節表面置換植入的設計、材料和效果,使其更加可靠,並適用於更廣泛的患者群體。其中一項特別顯著的進步是現代金屬對金屬(MoM)植入材料的研發,例如鈷鉻合金。這些材料具有優異的耐磨性和生物相容性,確保置換後的關節能夠承受日常活動的壓力,並保持良好的功能,而不會出現明顯的磨損。鈷鉻合金的應用解決了早期髖關節表面置換植入物(尤其是年輕、活躍的患者)長期存在的植入耐久性和磨損問題。
先進的製造技術,例如3D列印和電腦輔助設計(CAD),正在提升髖關節表面置換植入的精確度和客製化程度。 CAD技術使外科醫生能夠詳細模擬患者的髖關節,從而設計出與每位患者解剖結構相符的植入。這種個人化的植入設計方法能夠改善關節表面置換後的貼合度和功能,並降低植入鬆動和移位等併發症的風險。 3D列印技術也使製造商能夠生產高精度、患者特異性的組件,從而提高髖關節置換術的整體成功率。
手術技術和器械的進步也促進了髖關節植入的成功。現代微創手術方法可以縮小切口,減少術中組織損傷,進而縮短恢復時間,降低併發症風險。電腦輔助導航系統可在手術中提供即時影像和回饋,幫助外科醫生達到最佳的植入放置和對位,確保更好的手術效果。手術器械和技術的這些進步,縮短了恢復時間,最大限度地減少了術後併發症,並提高了植入的長期成功率。
其他重要的技術進步包括開發出能夠增強植入與骨組織整合的表面塗層和處理方法。例如,羥基磷灰石塗層可以增強金屬植入與患者自身骨骼之間的結合,從而促進更好的骨整合並降低植入鬆動的風險。此外,多孔植入表面也被引入,以促進骨骼長入植入,進一步提高長期穩定性。這些植入表面技術的創新使得髖關節置換術成為需要持久關節重建的患者更具可行性的長期解決方案。
目前,人們正在研究陶瓷塗層和金屬-陶瓷混合植入等替代材料,旨在降低金屬對金屬(MoM)植入釋放金屬離子的風險。雖然現代鈷鉻合金植入經久耐用且應用廣泛,但人們對金屬離子釋放的擔憂促使人們研究陶瓷和塗層材料,以期獲得類似的耐用性,同時避免相關風險。例如,陶瓷塗層植入有望提供更光滑、更耐磨的表面,同時最大限度地減少金屬離子的暴露。
物理治療和復健監測技術的進步也正在改善術後復健通訊協定。穿戴式科技和遠端醫療平台使醫護人員能夠遠端監測患者的復健進展,並根據即時數據調整復健計畫。這種個人化的復健方法不僅能加快復健速度,還能降低術後併發症的風險,例如關節僵硬和活動受限。
為什麼髖關節表面置換植入在現代整形外科治療中如此重要?
髖關節表面植入在現代整形外科治療中至關重要,因為它為全髖關節置換術(THR)提供了一個重要的替代方案,尤其適用於需要持久耐用關節解決方案的年輕活躍患者。雖然全髖關節置換術是一種高效的手術,但它需要切除患者相當一部分骨骼,並用人工股骨柄和髖臼杯進行替換。隨著時間的推移,這可能會導致骨質流失、植入鬆動以及需要翻修手術等併發症,尤其是在年輕患者中,他們的壽命可能超過植入的預期壽命。相較之下,髖關節置換術術可以保留更多患者的天然骨骼,從而降低未來併發症的風險,並提供更持久的解決方案。
對於55歲以下希望保持運動的患者而言,髖關節置換術通常是更好選擇,它能提供更高的穩定性並恢復自然的活動範圍。保留股骨頭和頸部可重建解剖學上的關節,從而降低與傳統全髖關節置換術相關的脫位風險。此外,髖關節表面置換術植入的設計旨在更自然地分散關節負荷,使患者能夠安全地恢復跑步、滑雪和運動等高強度運動。這些優勢使得手術成為運動員和其他希望術後保持高品質生活的活躍人士的理想選擇。
對於因骨質劣化而面臨翻修手術風險的患者而言,髖關節置換術術也是一個重要的選擇。對於因骨質疏鬆或多次手術導致骨質較差的患者,盡可能保留骨量對於關節重建的長期成功至關重要。由於髖關節置換術能夠保留股骨,因此可以延緩或避免全髖關節置換術的必要性。全髖關節置換術創傷較大,對骨質較差的患者而言也更具挑戰性。如果最終仍需進行全髖關節置換術,保留骨量的髖關節表面置換術可以保留足夠的骨量,從而提高重新置換置換術的成功率。
就耐用性而言,髖置換術在許多患者中都取得了良好的效果,其植入的存活率與傳統全髖關節置換術相當甚至更高,尤其是在選擇合適的患者的情況下。研究表明,植入位置適當的表面置換植入的患者預期存活時間為10至20年,與全置換術術相似,部分患者的植入存活時間甚至更長。隨著技術和材料的進步,髖關節表面置換植入的預期使用壽命有望更長,使其成為年輕患者越來越可行的長期解決方案。
髖置換術植入對於降低全髖關節置換術(THR)相關併發症(例如置換術骨折)的風險至關重要。在傳統的THR中,股骨柄會對剩餘骨骼施加壓力,這可能導致植入骨折。由於髖關節置換術不使用股骨柄,因此顯著降低了這些骨折的風險。這使其成為活動量大、跌倒風險高或術後骨折風險較高的患者的更安全選擇。
從經濟角度來看,髖置換術具有長期節省成本的潛力。雖然其初始費用與傳統全置換術相當或略高,但由於減少了重新置換手術和額外治療的需求,從長遠來看,它是一種更具成本效益的解決方案。較少的併發症和更長的植入使用壽命使患者能夠避免重新置換手術帶來的高昂醫療費用和漫長的恢復期。因此,對於希望降低整體醫療成本的患者和醫療系統而言,髖關節置換術術都是一個極具吸引力的選擇。
哪些因素正在推動髖關節表面置換植入市場的成長?
髖關節表面置換植入市場的成長受多種關鍵因素驅動,包括對保骨治療的需求不斷成長、植入技術的進步、人口老化但活躍度依然高,以及人們對整形外科解決方案的認知不斷提高。其中一個關鍵促進因素是年輕患者對全髖關節置換術替代方案的需求日益成長。隨著60歲以下患者(尤其是那些生活方式活躍的患者)髖關節骨關節炎和關節損傷的診斷率不斷上升,對持久耐用且保骨的治療方案(例如髖關節置換術)的需求也日益成長。髖關節置換術能夠幫助患者保持活動水平,同時降低傳統髖置換術相關的風險,因此對於那些希望避免一生中多次手術的患者來說,它極具吸引力。
植入材料、設計和手術技術的進步也推動了市場成長。更耐用的金屬合金、更先進的表面處理技術以及精密製造的植入,顯著提高了髖關節表面置換術植入的安全性和耐用性。這些創新降低了併發症的風險,改善了術後效果,使手術對患者和外科醫生都更具吸引力。此外,電腦輔助手術和機器人輔助技術的廣泛應用,使髖關節置換術更加精準,並惠及更多病患。這提高了手術成功率,從而促進了患者對該手術的接受度。
人口老化也是推動髖關節置換術市場成長的主要因素之一。隨著人們壽命延長,且老年時期仍保持著較為活躍的生活方式,對兼具耐用性和長期功能的整形外科解決方案的需求日益成長。髖置換術為那些希望參與高強度體能活動但又不適合全髖關節置換術的長者提供了一種解決方案。與全髖關節置換相比,置換術的限制更少,術後恢復積極生活方式的能力也更強,因此對於身體健康的老年人來說,它是一種極具價值的選擇。
人們對整形外科治療方案的認知度提高以及病患教育程度的提升,也促進了市場成長。現今的患者對治療方案的了解更加深入,並尋求微創、個人化且符合自身生活方式的手術。隨著髖關節表面置換術的益處,特別是其對骨骼的保護、活動能力的提升以及置換術風險的降低,越來越多的患者選擇該手術作為全髖關節置換術的替代方案。醫療機構和植入製造商加強市場推廣力度,加上患者術後良好的治療效果,共同推動了髖關節置換術成為可行的治療選擇。
推動市場成長的另一個因素是接受髖關節置換術訓練的外科醫師數量不斷增加。隨著越來越多的骨科醫生熟練這項手術,髖置換術的普及程度也不斷提高。這在傳統上整形外科醫療資源匱乏的地區尤其重要。隨著經驗豐富的外科醫生團隊不斷壯大,將有更多患者能夠接受這種保留骨骼的手術,從而進一步擴大市場。
最後,人們對個人化醫療和患者特異性治療方案的日益關注,推動了髖置換術的普及。病患和醫療服務提供者越來越重視個人化的治療方案,這些方案會考慮病患的生活方式、活動量和長期健康目標。髖置換術順應了這一趨勢,它提供了一種客製化的解決方案,既能保留患者的骨骼結構,又能增強術後的活動能力和功能。隨著個人化醫療不斷影響醫療保健領域,髖置換術仍將是尋求客製化整形外科解決方案的患者的重要選擇。
由於植入技術的進步、對保骨手術需求的增加以及整形外科醫療的興起,髖置換術植入市場預計將顯著成長。尤其對於年輕且更活躍的患者而言,他們正在尋求傳統全髖置換術的替代方案,因此,髖關節置換術將繼續在改善髖關節骨關節炎患者的生活品質和長期活動能力方面發揮關鍵作用。
部分:
材質(混合合金、鈷鉻合金、TiN塗層),最終用途(醫院、門診手術中心、整形外科診所)
人工智慧整合
我們正在利用檢驗的專家內容和人工智慧工具來變革市場和競爭情報。
Market Glass, Inc. 並沒有採用查詢LLM 或產業專用的SLM 的典型方法,而是建立了一個由世界各地領域專家精心策劃的內容庫,其中包括影片文字稿、部落格、搜尋引擎研究以及大量的公司、產品/服務和市場數據。
關稅影響係數
在最新發布的報告中,Market Glass, Inc. 將關稅對地理市場的影響納入考量,並根據公司總部所在地、製造地以及進出口(成品和OEM產品)情況,預測企業競爭地位的變化。這種複雜多變的市場現實會從多個方面影響競爭對手,包括增加銷貨成本、降低盈利和重組供應鏈,同時也會影響微觀和宏觀市場動態。
Global Hip Resurfacing Implants Market to Reach US$264.8 Million by 2030
The global market for Hip Resurfacing Implants estimated at US$223.5 Million in the year 2024, is expected to reach US$264.8 Million by 2030, growing at a CAGR of 2.9% over the analysis period 2024-2030. Hybrid Alloy Material, one of the segments analyzed in the report, is expected to record a 3.7% CAGR and reach US$128.9 Million by the end of the analysis period. Growth in the Cobalt Chromium Alloy Material segment is estimated at 2.4% CAGR over the analysis period.
The U.S. Market is Estimated at US$60.7 Million While China is Forecast to Grow at 2.8% CAGR
The Hip Resurfacing Implants market in the U.S. is estimated at US$60.7 Million in the year 2024. China, the world's second largest economy, is forecast to reach a projected market size of US$42.4 Million by the year 2030 trailing a CAGR of 2.8% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 2.7% and 2.4% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 3.1% CAGR.
Global Hip Resurfacing Implants Market - Key Trends and Drivers Summarized
Is Hip Resurfacing the Future of Orthopedic Solutions for Active Patients?
Hip resurfacing implants are reshaping the landscape of orthopedic surgery, but why are they emerging as a crucial option for patients with hip degeneration? Hip resurfacing is a bone-conserving alternative to traditional total hip replacement (THR), offering an option primarily for younger, active patients. Unlike THR, where the entire femoral head is removed and replaced with a prosthetic, hip resurfacing reshapes and caps the femoral head with a metal implant, while the acetabulum (hip socket) is also fitted with a metal component. This allows patients to retain more of their natural bone structure, improving stability and enabling a higher level of physical activity post-surgery.
The appeal of hip resurfacing lies in its durability and bone-preserving advantages, particularly for younger patients who may otherwise outlive a traditional hip implant and require revision surgery. By maintaining more of the patient’s bone and providing a more natural load distribution through the joint, hip resurfacing can enhance mobility and function, while reducing the likelihood of dislocation. For active individuals, hip resurfacing implants offer the potential for a more normal range of movement, making it a preferred choice for those who wish to maintain an active lifestyle after surgery. As the global population ages and the demand for more durable, long-lasting orthopedic solutions grows, hip resurfacing is gaining attention as an important option for managing hip osteoarthritis and other degenerative hip conditions.
How Has Technology Advanced Hip Resurfacing Implants?
Technological advancements have significantly improved the design, materials, and outcomes of hip resurfacing implants, making them more reliable and adaptable for a broader range of patients. One of the most notable advancements has been in the development of modern metal-on-metal (MoM) implant materials, such as cobalt-chromium alloys. These materials provide superior wear resistance and biocompatibility, ensuring that the resurfaced joint can withstand the stresses of daily activity without significant wear. The use of cobalt-chromium alloys has helped address the early concerns about implant longevity and wear that plagued earlier generations of hip resurfacing implants, particularly in younger, more active patients.
Advanced manufacturing techniques, such as 3D printing and computer-aided design (CAD), have also enhanced the precision and customization of hip resurfacing implants. With CAD, surgeons can now model the patient’s hip joint in detail, ensuring that the implant is tailored to fit the individual’s anatomy. This personalized approach to implant design improves the fit and function of the resurfaced joint, reducing the risk of complications such as implant loosening or misalignment. 3D printing has further allowed manufacturers to create highly precise, patient-specific components, improving the overall success rates of hip resurfacing surgeries.
Improvements in surgical techniques and instrumentation have also contributed to the success of hip resurfacing implants. Modern minimally invasive surgical approaches allow for smaller incisions and less tissue damage during the procedure, leading to faster recovery times and reduced risk of complications. Computer-assisted navigation systems, which provide real-time imaging and feedback during surgery, help surgeons achieve optimal implant placement and alignment, ensuring better outcomes. These technological advancements in both surgical tools and techniques have helped reduce recovery times, minimize post-operative complications, and improve long-term implant success.
Another significant technological advancement has been the development of surface coatings and treatments that improve the integration of the implant with bone tissue. For instance, hydroxyapatite coatings are used to enhance the bonding between the metal implant and the patient’s natural bone, promoting better osseointegration and reducing the risk of implant loosening. Porous implant surfaces have also been introduced to encourage bone growth into the implant, further improving long-term stability. These innovations in implant surface technology have made hip resurfacing a more viable long-term solution for patients who need durable joint replacements.
Research into alternative materials, such as ceramic coatings or hybrid metal-ceramic implants, is ongoing, with the goal of reducing the risks associated with metal ion release from MoM implants. Although modern cobalt-chromium implants are durable and widely used, concerns about metal ion release have prompted researchers to explore ceramic or coated materials that could offer similar durability without the same risks. Ceramic-coated implants, for example, have shown promise in providing a smoother, wear-resistant surface while minimizing metal ion exposure.
Post-surgery rehabilitation protocols have also improved thanks to advancements in physical therapy and recovery monitoring. Wearable technology and telemedicine platforms now allow healthcare providers to monitor patients' recovery progress remotely, adjusting rehabilitation plans based on real-time data. This personalized rehabilitation approach not only speeds up recovery but also reduces the risk of complications such as stiffness or limited mobility post-surgery.
Why Are Hip Resurfacing Implants Critical for Modern Orthopedic Treatment?
Hip resurfacing implants are critical for modern orthopedic treatment because they provide an important alternative to total hip replacement (THR), especially for younger, active patients who need durable, long-lasting joint solutions. While THR is a highly effective procedure, it involves removing a significant portion of the patient’s bone and replacing it with a prosthetic femoral stem and acetabular cup. Over time, this can lead to complications such as bone loss, implant loosening, or the need for revision surgery, particularly in younger patients who may outlive their first implant. In contrast, hip resurfacing preserves more of the patient’s natural bone, reducing the likelihood of future complications and providing a longer-lasting solution.
For patients under 55 who wish to remain physically active, hip resurfacing is often the preferred option because it provides greater stability and allows for a more natural range of motion. The preservation of the femoral head and neck results in a more anatomically aligned joint, which reduces the risk of dislocation-a common concern with traditional hip replacements. Additionally, hip resurfacing implants are designed to distribute load more naturally across the joint, allowing for high-impact activities such as running, skiing, or sports to be safely resumed. This makes hip resurfacing an attractive option for athletes, active individuals, or those who wish to maintain a high quality of life post-surgery.
Hip resurfacing is also an important option for patients who may be at risk of revision surgery due to bone degradation. In cases where bone quality is compromised-either by osteoporosis or multiple previous surgeries-preserving as much bone as possible is essential to ensure the long-term success of any joint replacement. Hip resurfacing preserves the femoral bone, allowing patients to delay or avoid the need for total hip replacement, which is more invasive and often more challenging in patients with poor bone quality. Should a patient eventually require a full hip replacement, the bone-conserving nature of hip resurfacing ensures there is enough bone left for the revision procedure to be successful.
In terms of longevity, hip resurfacing has demonstrated favorable outcomes for many patients, with implant survival rates that are comparable to or better than those of traditional hip replacements, especially in appropriately selected patients. Studies have shown that patients with well-placed resurfacing implants can expect 10- to 20-year survival rates similar to THR, with some patients retaining their implants even longer. As technology and materials continue to improve, the lifespan of hip resurfacing implants is expected to increase, making them an increasingly viable long-term solution for younger patients.
Hip resurfacing implants are also critical in reducing the risk of certain complications associated with total hip replacements, such as periprosthetic fractures. In traditional THR, the femoral stem can sometimes cause stress on the remaining bone, leading to fractures around the implant. Because hip resurfacing avoids the use of a femoral stem, the risk of these fractures is significantly reduced. This makes it a safer option for patients with higher activity levels or those with a higher risk of falls, who may be more prone to fractures after surgery.
From an economic perspective, hip resurfacing also offers potential cost savings over time. While the initial cost of hip resurfacing surgery may be comparable to or slightly higher than traditional THR, the reduced likelihood of requiring revision surgery or additional procedures makes it a more cost-effective solution in the long term. Fewer complications and longer implant life mean that patients can avoid the significant medical costs and recovery times associated with revision surgeries, making hip resurfacing an attractive option both for patients and healthcare systems looking to reduce overall treatment costs.
What Factors Are Driving the Growth of the Hip Resurfacing Implant Market?
The growth of the hip resurfacing implant market is driven by several key factors, including the increasing demand for bone-conserving treatments, advancements in implant technology, the aging but active population, and the rising awareness of personalized orthopedic solutions. One of the primary drivers is the growing demand for alternatives to total hip replacement among younger patients. As more people under 60 are diagnosed with hip osteoarthritis or joint damage, particularly those who lead active lifestyles, the need for durable, bone-preserving options like hip resurfacing has grown. Hip resurfacing allows these patients to maintain their activity levels while reducing the risks associated with traditional hip replacement, making it an attractive option for a demographic seeking to avoid multiple surgeries over their lifetime.
Technological advancements in implant materials, design, and surgical techniques are also contributing to the market growth. The development of more durable metal alloys, better surface treatments, and precision-manufactured implants has significantly improved the safety and longevity of hip resurfacing implants. These innovations have made the procedure more appealing to both patients and surgeons, as they reduce the risk of complications and improve post-operative outcomes. Additionally, the rise of computer-assisted surgery and robotic-assisted techniques has improved the precision of hip resurfacing, making it more accessible and increasing success rates, which in turn drives greater adoption.
The aging population is another major factor driving the growth of the hip resurfacing market. As people live longer and remain active well into their later years, the demand for orthopedic solutions that offer durability and long-term functionality is increasing. Hip resurfacing offers a solution for older adults who still wish to engage in physically demanding activities but may not be ideal candidates for total hip replacement. The ability to return to an active lifestyle after hip resurfacing, with fewer restrictions compared to total hip replacement, makes it a valuable option for older, yet physically fit individuals.
Rising awareness and patient education about orthopedic options are also contributing to the growth of the market. Patients today are more informed about their treatment options and are seeking out less invasive, more personalized procedures that align with their lifestyles. As more people learn about the benefits of hip resurfacing-especially its ability to preserve bone, improve mobility, and reduce the risk of dislocation-more patients are requesting this procedure as an alternative to total hip replacement. Increased marketing by healthcare providers and implant manufacturers, coupled with positive patient outcomes, has helped raise awareness of hip resurfacing as a viable option.
Another factor driving market growth is the growing number of surgeons trained in hip resurfacing techniques. As more orthopedic surgeons become proficient in the procedure, the availability of hip resurfacing is increasing. This is particularly important in regions where access to advanced orthopedic care may have been limited in the past. As the pool of experienced surgeons grows, more patients will have access to this bone-conserving procedure, further expanding the market.
Finally, the increasing focus on personalized medicine and patient-specific treatments is driving the adoption of hip resurfacing. Patients and healthcare providers are placing greater emphasis on individualized treatment plans that take into account a patient’s lifestyle, activity level, and long-term health goals. Hip resurfacing aligns with this trend by offering a tailored solution that preserves the patient’s bone structure while allowing for greater mobility and function post-surgery. As personalized medicine continues to influence the healthcare landscape, hip resurfacing will remain an important option for patients seeking customized orthopedic solutions.
With advancements in implant technology, the growing demand for bone-preserving procedures, and the rise of personalized orthopedic care, the hip resurfacing implant market is poised for significant growth. As more patients, particularly younger and more active individuals, seek alternatives to traditional hip replacement, hip resurfacing will continue to play a critical role in improving quality of life and enabling long-term mobility for those with degenerative hip conditions.
SCOPE OF STUDY:
The report analyzes the Hip Resurfacing Implants market in terms of units by the following Segments, and Geographic Regions/Countries:
Segments:
Material (Hybrid Alloy, Cobalt Chromium Alloy, TiN Coated); End-Use (Hospitals, Ambulatory Surgery Centers, Orthopedic Clinics)
Geographic Regions/Countries:
World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; and Rest of Europe); Asia-Pacific; Rest of World.
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