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市場調查報告書
商品編碼
1382479
酵素替代療法市場規模 - 按酵素(Alglucosidase alfa、Agalsidase beta、Imiglucerase)、適應症(Gaucher、MPS、Pompe、SCID、Fabry)、給藥途徑、最終用戶、2023-2032 年全球預測Enzyme Replacement Therapy Market Size - By Enzyme (Alglucosidase alfa, Agalsidase beta, Imiglucerase), Indication (Gaucher, MPS, Pompe, SCID, Fabry), Route of Administration, End-user, Global Forecast 2023-2032 |
由於生物製劑和各種遺傳性疾病的標準治療方法得到更廣泛的接受,酵素替代療法市場規模預計在 2023 年至 2032 年期間CAGR將超過 7%。
包括酵素替代療法 (ERT) 在內的生物製劑作為戈謝病和法布瑞氏症等遺傳性疾病的先進標靶治療方法越來越受到重視。生物製劑的治療功效和特異性以及隨後在患者和醫療保健提供者中越來越多的採用也將促進市場成長。例如,2023年11月,武田的ADZYNMA獲得美國FDA批准,成為第一個也是唯一一個用於治療先天性血栓性血小板減少性紫斑症(cTTP)的重組ADAMTS13酶替代藥物。
酵素替代療法產業分為酵素類型、適應症、給藥途徑、最終使用者和地區。
就酵素類型而言,預計 2023 年至 2032 年伊米苷酶領域的市值CAGR將達到 8.4%。伊米苷酶已成為治療戈謝氏症的有效酵素替代療法。不斷擴大的患者群體,加上對罕見疾病的認知和診斷不斷提高,正在擴大對基於伊米苷酶的 ERT 的需求。此外,生物技術的不斷進步和持續研究將有助於該領域的成長。
根據最終用戶,輸液中心領域的 ERT 產業到 2032 年可能會實現 7.5% 的CAGR。酵素缺乏症盛行率的上升,加上酵素替代療法的接受度不斷提高,將大大增加對輸液中心服務的需求。此外,由於提供方便且受控的治療環境,患者對輸液中心的偏好不斷增加,這可能會支持該細分市場的成長。
從地區來看,由於先進的醫療基礎設施、意識的提高以及酵素缺乏症盛行率的上升,到 2032 年,歐洲酵素替代療法市場規模預計將實現 6.8% 的CAGR。此外,歐洲製藥公司和研究機構之間的合作將有助於促進 ERT 技術的進步。此外,越來越多的致力於透過創新療法改善患者治療結果將增強該地區的行業前景。例如,2023 年 5 月,歐盟委員會授予了 pegunigalsidase alfa 的行銷授權,這是一種用於治療法布瑞氏症的聚乙二醇 (PEG) 化酶。
Enzyme Replacement Therapy Market size is set to exhibit over 7% CAGR from 2023 to 2032, driven by the broader acceptance of biologics and standard treatments for various genetic disorders.
Biologics, including enzyme replacement therapy (ERT) are gaining prominence as advanced and targeted treatments for genetic disorders, such as Gaucher disease and Fabry disease. The therapeutic efficacy and specificity of biologics and the subsequently rising adoption amongst patients and healthcare providers will also boost the market growth. For instance, in November 2023, Takeda's ADZYNMA received clearance from the U.S. FDA as the first and only recombinant ADAMTS13 enzyme replacement medication for the treatment of congenital thrombotic thrombocytopenic purpura (cTTP).
The enzyme replacement therapy industry is segmented into enzyme type, indication, route of administration, end-user, and region.
With respect to enzyme type, the market value from imiglucerase segment is anticipated to attain 8.4% CAGR from 2023-2032. Imiglucerase has emerged as an effective enzyme replacement therapy for the treatment of Gaucher disease. The expanding patient pool coupled with the rising awareness and diagnosis of rare diseases is amplifying the demand for Imiglucerase-based ERTs. Moreover, the rising advancements in biotechnology and continuous research will contribute to the segment growth.
Based on end-user, the ERT industry from the infusion centers segment is likely to record 7.5% CAGR through 2032. The rising prevalence of enzyme deficiency disorders coupled with the increasing acceptance of enzyme replacement therapies is adding significantly to the demand for infusion center services. Additionally, the increasing patient preference for infusion centers due to the availability of convenient and controlled environment for the treatment is likely to support the segment growth.
Regionally, the Europe enzyme replacement therapy market size is slated to observe 6.8% CAGR through 2032 driven advanced healthcare infrastructure, increasing awareness, and the rising prevalence of enzyme deficiency disorders. Moreover, collaborations between pharmaceutical companies and research institutions in Europe will contribute to increasing advancements in ERT technologies. Additionally, the growing commitment to improving patient outcomes through innovative therapies will augment the regional industry outlook. For instance, in May 2023, the European Commission granted marketing authorization for pegunigalsidase alfa, the Poly (ethylene glycol) (PEG) ylated enzyme for Fabry disease.