超越 CRISPR：DNA 重寫領域的最新技術進展

Beyond CRISPR: Recent Technology Advances in Rewriting DNA

出版日期: 2025年10月22日 | 出版商:

Frost & Sullivan | 英文 57 Pages | 商品交期: 最快1-2個工作天內

價格

簡介目錄

重塑基因編輯未來的新工具

本研究檢驗了CRISPR/Cas系統以外的新興下一代基因編輯技術，重點在於先導編輯、鹼基編輯、橋接RNA、SeekRNA和基因寫入平台等進展。這些工具具有更強大的編輯能力、更低的脫靶效應和更高的精確度，使其在治療方法開發、精準醫療和功能基因組學領域具有突破性意義。為了提高基因組編輯的精確度和效率，本研究著重介紹了人工智慧（AI）和機器學習在引導RNA最佳化、脫靶預測和可擴展臨床應用方面的應用。透過分析包括學術聯盟、大型製藥企業、生物技術Start-Ups公司和提供AI驅動編輯解決方案的公司在內的關鍵相關人員，本研究展現了合作創新生態系統的全貌。此外，為了評估商業化準備情況，本研究檢驗了北美、歐洲、亞太地區和新興地區的全球資金籌措趨勢、投資模式和法規環境。透過識別成長前景和策略聯盟，本研究揭示了顛覆性工具如何改變基因醫學和生物技術的未來。

精準編輯－拓展基因編輯的精確性和多功能性
Prime Editing 的最新創新
橋接RNA—第三代基因工程
SeekRNA—一種精準基因編輯的新方法
表觀基因編輯
鹼基編輯：實現單核苷酸精確度
低音編輯領域的最新創新
基因編寫—基因組工程的新藍圖
基因寫作領域的最新進展

人工智慧和機器學習在基因編輯的應用

人工智慧與機器學習：人工智慧/機器學習在基因編輯的應用
基因編輯和人工智慧領域的新興趨勢

推進基因編輯技術向臨床應用：相關人員和解決方案

參與基因編輯技術開發的相關人員

資金籌措和合作趨勢

2023-2025年全球關鍵基因編輯合作項目
產業資金籌措概況 -全球2023-2025 年
學術資金籌措概況 -全球2023-2025 年
基因編輯的區域趨勢：進展與應用

成長機會領域－超越 CRISPR 的 DNA 基因編輯

成長機會 1：人工智慧驅動的基因編輯中的指導序列設計與脫靶預測
成長機會2：下一代基因編輯工具
成長機會 3：大規模 DNA 整合與重寫

附錄

TRL：詳解

未來發展

成長機會帶來的益處和影響
下一步
免責聲明

簡介目錄

Product Code: DB4D

Emerging Tools Reshaping the Future of Gene Editing

This study highlights advancements such as prime editing, base editing, bridge RNA, SeekRNA, and gene writing platforms, as it examines the emerging field of next-generation gene editing technologies beyond CRISPR/Cas systems. These tools are revolutionary for therapeutic development, precision medicine, and functional genomics because they provide increased editing capabilities, decreased off-target effects, and improved precision. To improve accuracy and efficiency in genome engineering, the study highlights the use of artificial intelligence (AI) and machine learning for guide RNA optimization, off-target prediction, and scalable clinical translation. The collaborative innovation ecosystem is mapped by examining key stakeholders, including academic consortia, large pharmaceutical companies, biotech start-ups, and companies that provide AI-driven editing solutions. Additionally, to evaluate commercialization readiness, global funding trends, investment patterns, and regulatory environments in North America, Europe, Asia-Pacific, and emerging regions are examined. The study highlights how disruptive tools are changing the future of genetic medicine and biotechnology by spotting growth prospects and strategic partnerships.

Strategic Imperatives

Why Is It Increasingly Difficult to Grow?
The Strategic Imperative 8
The Impact of the Top 3 Strategic Imperatives on the Beyond CRISPR Rewriting DNA Space
Growth Opportunities Fuel the Growth Pipeline Engine
Research Methodology

Growth Opportunity Analysis

Scope of Analysis
Segmentation

Growth Generator

Growth Drivers
Growth Restraints

CRISPR Technology: Mechanism, Advantages, and Limitations

CRISPR-Clustered Regularly Interspaced Short Palindromic Repeats
Pros and Cons of CRISPR Gene Editing

Next-Generation Gene Editing Technologies

Prime Editing-Expanding Accuracy and Versatility in Gene Editing
Recent Innovations in Prime Editing
Bridge RNA-The Third Generation of Genetic Engineering
SeekRNA-A New Pathway for Accurate Gene Editing
Epigenome Editing
Base Editing: Unlocking Single-Nucleotide Precision
Recent Innovations in Base Editing
Gene Writing-A New Blueprint for Genome Engineering
Recent Innovations in Gene Writing

AI & Machine Learning in Gene Editing

AI and Machine Learning AI/ML in Gene Editing
Emerging Trends in Gene Editing and AI

Translating Gene Editing to Clinical Impact: Stakeholders and Solutions

Stakeholders Developing Gene Editing Technologies

Funding and Collaboration Landscape

Key Collaborations in Gene Editing Technologies-Global 2023-2025
Snapshot of Industry Funding-Global 2023-2025
Snapshot of Academia Funding-Global 2023-2025
Regional Trends in Gene Editing-Developments and Adoption

Growth Opportunity Universe-Beyond CRISPR Rewriting DNA

Growth Opportunity 1: AI-Driven Guide Design and Off-Target Prediction in Gene Editing
Growth Opportunity 2: Next-Generation Gene Editing Tools
Growth Opportunity 3: Large DNA Integration and Rewriting