![]() |
市場調查報告書
商品編碼
1811968
癌症免疫療法市場成長機會(2024-2030)Growth Opportunities in the Immuno-oncology Therapeutics Market, 2024-2030 |
下一代免疫療法、人工智慧和生物標記驅動的個人化治療進步將推動轉型成長
全球癌症發生率預計將從2022年的2,000萬例增加77%,到2050年將超過3,500萬例。飲酒、吸菸、肥胖和空氣污染是導致癌症發生率上升的主要原因。現今的癌症研究重點是細胞和基因治療、抗體藥物複合體(ADC)、查核點抑制劑和多特異性抗體。臨床試驗主要集中於放射線治療、化療和多種免疫療法藥物的組合,目前有超過5000種癌症免疫療法開發中。
免疫腫瘤學(IO)徹底改變了癌症治療,但必須應對臨床試驗挑戰,以改善患者預後並加快核准。許多免疫腫瘤學療法在規模過大或患者群體不匹配的情況下進行評估,最終失敗。人體免疫反應並非總是能夠透過動物模型或2D體外系統預測。傳統的隨機對照試驗無法檢測出藥物未達到預期療效的徵兆,也不需要持續調整藥物。
人工智慧和生物標記指導的患者選擇、抵消抗藥性的聯合療法、免疫相關不利事件的即時安全監測、改善患者可及性的分散式臨床試驗以及自適應的人工智慧主導的試驗設計是應對這些挑戰的基本策略。這些方法使相關人員能夠增強腫瘤免疫療法創新,並提高癌症治療的有效性、可近性和安全性。
改良的生物標記平台有助於提升對腫瘤免疫生物學認知的深度和精準度。生物標記研究的快速發展領域包括多重免疫組化(IHC)、基於NGS的基因突變和表現圖譜檢測、高階基因結構的表觀遺傳圖譜繪製以及腫瘤能量狀態的代謝譜分析。
本研究檢視了臨床和管道發展、技術創新和區域市場動態,以概述2025年至2030年全球 IO 市場和收益預測。地理覆蓋範圍包括北美、歐洲、亞太、中東和北非以及拉丁美洲。
本研究檢驗了推動免疫治療發展的關鍵主題和技術,重點關注查核點抑制劑、抗體偶聯藥物(ADC)、雙特異性抗體、癌症疫苗以及過繼性細胞療法,包括 CAR-T、TCR 和 TIL。研究重點關注策略目標領域,包括克服對 PD-1/PD-L1 抑制劑的抗藥性,以及下一代藥物,包括同種異體療法和特異性治療方法。在這種動態環境中,本研究也探討了成長促進因素、阻礙因素以及相關人員的機會。
收益及預測
2024年營收將達到 1,106.9億美元,在2021年至2030年的研究期間內,年複合成長率(CAGR)為 10.7%。
三大戰略要務對生醫治療產業的影響
壓縮客戶價值鏈
為什麼
壓迫免疫腫瘤學市場的價值鏈意味著最佳化和簡化患者的診療過程,包括診斷、治療和術後護理。這可以透過整合各種醫療服務並利用免疫腫瘤學臨床試驗市場的尖端技術來實現。
全面全面的癌症治療非常重要,特別是在市場脈絡,包括綜合治療設施、協調的護理團隊和廣泛的後續護理計劃。
觀點
免疫腫瘤學市場的公司提供直接面對消費者的服務,例如家用癌症風險基因檢測套組,以加速診斷過程。
數位技術在自適應、人工智慧主導的癌症臨床試驗市場脈絡最佳化營運、提高病人參與並客製化護理,包括遠端諮詢、資料驅動的診斷和治療建議。
透過將種族、年齡和社會經濟因素緊密結合到生存和臨床決策中,腫瘤學價值鏈可以顯著改善免疫腫瘤生物標記平台市場的患者體驗。
顛覆性技術
為什麼
最近的技術進步,包括單細胞定序和空間轉錄組學,大大增強了對腫瘤微環境免疫生物學的理解,影響了自適應人工智慧驅動的癌症臨床試驗市場。
一種新的人工智慧方法利用治療變化預測來識別臨床試驗候選者,並推動了次世代定序儀(NGS)資料在下一代免疫腫瘤學市場中用於患者試驗匹配的應用。一種機器學習演算法利用患者報告的結果變數來預測急性癌症治療的發生率。
Sanofi與Owkin合作,以加強生物標記識別並提高臨床試驗的成功率,而GSK則與Tempus合作,以支持其在免疫腫瘤學市場的努力。
觀點
多重模式方法增進了對與免疫腫瘤學市場相關的腫瘤-免疫系統交互作用的理解。數位化工具有助於組織資料、揭示複雜模式並靈活提取免疫學相關資訊。由於致力於免疫療法創新的公司寥寥無幾,因此選擇非常重要。
人工智慧和加速運算徹底改變醫療保健,NVIDIA 等公司大力投資醫療保健服務,包括 IOVIA、Illumina 和 Mayo Clinic,影響著自適應人工智慧主導的癌症臨床試驗市場。
競爭激烈程度
為什麼
免疫腫瘤學市場競爭激烈,多家公司追求類似的臨床目標,大型製藥公司與新興生物技術公司合作,在免疫腫瘤學臨床試驗市場中尋求新資產。
隨著免疫療法、放射線治療、標靶治療和微生物組調節等新興需求的融合,臨床開發和法規環境變得更加複雜。
免疫腫瘤生物標記平台市場在細胞療法、腫瘤病毒、mRNA 疫苗和人工智慧生物標記發現方面取得了進展,推動了許多策略合作夥伴關係、合資企業、合併和收購。
觀點
儘管近年來取得了一些突破,但癌症免疫療法領域在臨床試驗市場中仍面臨諸多障礙,包括療效有限、療效持續時間短暫以及副作用意外等。一種常見的策略是致力於透過精準標靶藥物應用於特定的患者群體和腫瘤類型,實現差異化。
影響因素:人類推動公司透過RWE最佳化其品牌擴大策略。市場RWE推動早期小細胞肺疾病的退出。
促進因素
成長阻礙因素
Advances in Next-Generation Immunotherapies, AI, and Biomarker-Driven Personalization are Driving Transformational Growth
Worldwide cancer incidence is expected to exceed 35 million new cases by 2050, a 77% rise from the 20 million cases in 2022. Alcohol intake, tobacco usage, obesity, and air pollution are the main causes of this increase. Cancer studies today emphasize cell and gene therapy, antibody-drug conjugates (ADCs), checkpoint inhibitors, and multi-specific antibodies. With clinical trials emphasizing combinations of radiation, chemotherapy, or many immunotherapy medicines, more than 5,000 immuno-oncology medications are under development.
Although immuno-oncology (I-O) has revolutionized cancer therapy, problems with clinical trials must be resolved to improve patient outcomes and speed approvals. Many I-O therapies show failure when evaluated across too-large or incompatible patient groups; human immune responses cannot always be deduced from animal models and two-dimensional in vitro systems. Conventional randomized controlled studies may not find signs or call for continuous changes should a medicine not be functioning as expected.
AI and biomarker-based patient selection, combination approaches to offset resistance, real-time safety monitoring for immune-related adverse events, distributed clinical trials to improve patient access, and adaptive, AI-driven trial designs are fundamental strategies to meet these challenges. With these approaches, stakeholders are strengthening I-O innovation and improving the effectiveness, accessibility, and safety criteria of cancer therapy.
Improved biomarker platforms help to increase tumor immunobiology's depth of knowledge and accuracy. Fast-growing fields in biomarker research include multiplex IHC, NGS-based testing for gene mutations and expression profiles, epigenetic mapping for higher-order gene structures, and metabolic profiling for tumor energy status.
Frost & Sullivan studied clinical and pipeline developments, technological innovation, and regional market dynamics to develop this research service, which provides an overview of the global I-O market and a revenue projection from 2025 to 2030. The geographical scope is North America, Europe, Asia-Pacific, the Middle East and North Africa, and Latin America.
With an eye on checkpoint inhibitors, ADC, bispecific antibodies, cancer vaccines, and adoptive cell treatments including CAR-T, TCR, and TILs, this report examines the main themes and technologies driving the evolution of I-O therapies. Along with strategic target areas including overcoming resistance to PD-1/PD-L1 inhibitors, it stresses next-generation drugs including allogeneic approaches and multi-specific modalities. In this fast-changing environment, the study also investigates growth drivers, restraints, and opportunities for stakeholders.
Revenue Forecast
The revenue estimate for the base year 2024 is projected at $110.69 billion, with a compound annual growth rate (CAGR) of 10.7% during the study period from 2021 to 2030.
The Impact of the Top 3 Strategic Imperatives on the I-O Therapeutics Industry
Customer Value Chain Compression
Why
Patient value chain compression in the immuno-oncology market entails optimizing and simplifying the patient's journey, including the stages of diagnosis, treatment, and post-treatment care. This is accomplished by combining different healthcare services and using cutting-edge technology in immuno-oncology clinical trials market.
Comprehensive, integrated cancer care is important, especially in the context of the immuno-oncology biomarker platforms market. Integrated treatment facilities, coordinated care teams, and extensive aftercare plans are examples of this.
Frost Perspective
Companies in the immuno-oncology market are providing direct-to-consumer services, such as cancer risk genetic testing kits that may be used at home thus expedite the diagnosing process.
Digital technology optimizes operations, improves patient engagement, and customizes treatment in the context of the adaptive AI-driven oncology trials market. This includes remote consultations, data-driven diagnostics, and treatment recommendations.
By tightly integrating racial, age, and socioeconomic considerations into their survival and clinical decision-making, the oncology value chain can significantly improve patients' experiences within the immuno-oncology biomarker platforms market.
Disruptive Technologies
Why
Recent technological advancements, including single-cell sequencing and spatial transcriptomics, have greatly enhanced our understanding of the immunobiology of the tumor microenvironment, influencing the adaptive AI-driven oncology trials market.
A new AI method uses treatment change predictions to identify clinical trial candidates, advancing the use of next-generation sequencing (NGS) data for patients' trial matching in the next-generation immuno-oncology therapies market. A machine learning algorithm predicts cancer acute care occurrences using patient-reported outcome variables.
Sanofi is collaborating with Owkin to boost biomarker identification and raise clinical trial success rates. GSK has teamed with Tempus to aid the effort in the immuno-oncology market.
Frost Perspective
Multi-modality methods have improved our understanding of tumor-immune system interactions relevant to the immuno-oncology market. Digital tools help to organize data, uncover complicated patterns, and extract immunologically relevant information in a flexible way. Since few companies respond to innovations in immunotherapy, it is crucial to select.
AI and accelerated computing are revolutionizing medicine, and companies like NVIDIA are investing heavily in healthcare services, including IOVIA, Illumina, and Mayo Clinic, impacting the adaptive AI-driven oncology trials market.
Competitive Intensity
Why
The immuno-oncology market is competitive, with several companies aiming for similar clinical targets and big pharma teaming up with emerging biotech for novel assets in the immuno-oncology clinical trials market.
Clinical development and regulatory environments are complicated by the convergence of immunotherapy, radiation, targeted treatments, and new demands, such as microbiome regulation.
Cell treatments, oncologic viruses, mRNA vaccines, and AI-driven biomarker discovery are advancing in the immuno-oncology biomarker platforms market. These developments have driven many strategic alliances, joint ventures, mergers, and acquisitions.
Frost Perspective
Despite recent breakthroughs, there are still obstacles in the field of cancer immunotherapy within the immuno-oncology clinical trials market. These include limited effectiveness, temporary duration, and unintended impacts. Under a general strategy, differentiating via precision targets medicines for certain patient groups or tumor types has become a focal point.
Factors: Human beings are asking companies to optimize label expansion strategies via RWE. Market RWE will facilitate escape from earlier stages of the small cell lung.
Growth Drivers
Growth Restraints