次世代定序儀(NGS) 和基因組分析的進展

Advancements in Next-gen Sequencing and Genomic Analysis

出版日期: 2023年12月07日 | 出版商:

Frost & Sullivan | 英文 67 Pages | 商品交期: 最快1-2個工作天內

價格

簡介目錄

NGS 平台和基因組分析確保精準醫學的變革性成長

定序技術多年來不斷發展，能夠充分利用人類基因組的價值，並深入了解 DNA 和 RNA 序列，從而提供豐富的人類生物學知識。從Sanger測序到新一代定序，技術和化學方法不斷改進和發展，以降低成本並加快進度。 NGS 正在被涵蓋基礎生命科學研究中，以了解疾病生物學以進行藥物研發和診斷。

NGS化學的發展，包括單分子即時測序、合成測序、奈米孔測序以及離子和半導體技術，以及測序設備的小型化和NGS的自動化，正在推動NGS在生物實驗室的採用。。全基因組定序、標靶定序、全EXOME定序和單細胞 RNA 定序均可精確定位和識別結構變異、SNP、遺傳變異、病原體檢測、患者分層、藥物研發等。在體學。

NGS 市場目前正在見證新興企業的崛起，這些企業提供改進的化學方法和設備來提供低成本的全基因組定序，從而提高全部區域的採用率並推動精準醫療。用於分析定序資料的人工智慧/機器學習平台的技術進步有助於在數小時內分析和解釋大量定序資料。 NGS在資料主導的臨床醫學中發揮重要作用，並將繼續改善全球醫療保健系統。該分析強調了 NGS 和基因組分析平台的發展，這些平台使全基因組定序更容易實現，並加速早期臨床決策，以獲得更好的健康結果。

定序方法的演變
導致先進定序技術改進的關鍵重點領域
NGS 的重要性和能力日益增強
技術干預提高C
NGS 從焦磷酸測序到高級 NGS 的演變
NGS定序化學及其採用
NGS 化學類型
業界領先的相關人員形勢和 NGS 平台
市場領導正在進行的定序技術開拓
改善基因組結果的策略
新興市場參與者專注於提高自動化、人工智慧整合和定序化學
使用 NGS 的準確快速的核酸定序方法
NGS 方法和基因組分析的趨勢
機器人技術、液體處理和文庫製備的進步推動了 NGS 自動化系統的發展
專注於 NGS 自動化的關鍵推動因素
人工智慧在促進基因組分析中的作用
專注於NGS分析的人工智慧和生物資訊學平台的主要企業
NGS測序供應商和整合服務的產業形勢

應用

NGS 在各種應用中的採用不斷成長
NGS 和基因組分析改進了疾病診斷的突變分析和生物標記發現
不斷發展的 NGS 協作和技術平台，以開發基於 NGS 的快速診斷測試
NGS 和基因組分析改進了精準醫療的預測分析
專注於使用 NGS 進行精準醫療的主要企業
改進 NGS 和基因組分析
成長中的基於 NGS 的藥物研發公司
次世代定序儀的未來

研發合作

擴大網路收購以提高 NGS 能力
全球公共資金和聯盟努力促進技術知識和合作研究

成長機會宇宙

成長機會 1：經濟實惠的定序服務
成長機會 1：經濟實惠的定序服務
成長機會 2：低收入和中等收入國家的臨床總體基因體學
成長機會3：平台安全與監管
成長機會3：平台安全與監管

附錄

技術完備等級(TRL)：說明

下一步

簡介目錄

Product Code: DABB

NGS Platforms and Genomic Analysis to Ensure Transformational Growth of Precision Medicine

Sequencing technologies have evolved over the years to harness the value of the human genome and dive deep into DNA and RNA sequences which offer immense knowledge of human biology. From Sanger sequencing to next-generation sequencing, technologies and chemistries have improved/advanced to reduce costs and ensure faster timelines. NGS has integrated itself into basic life science research to understand disease biology for drug development and diagnostics.

Developments in NGS chemistries such as single-molecule real-time sequencing, sequencing by synthesis, nanopore sequencing, ion and semiconductor technology, in addition to miniaturization of sequencing instrumentation and automation of NGS, boost the adoption of NGS across biological labs. Whole genome sequencing, targeted sequencing, whole exome sequencing, whole transcriptome sequencing, and single-cell RNA sequencing have all found specific applications across omics where they accurately indicate and identify structural variants, SNPs, genetic variations, pathogen detection, patient stratification, drug discovery, and so on.

The NGS market is now witnessing a rise in emerging players that offer improved chemistries and instrumentation to deliver low-cost whole genome sequencing, increasing adoption across geographies and driving precision medicine. Technological advancement of AI-/ML-powered platforms for analyzing sequencing data is helping analyze and interpret large volumes of sequencing data within hours. NGS plays a key role in data-driven clinical medicine and will continue to improve the global healthcare system. The analytics covers developments in NGS and genomic analysis platforms that will make whole genome sequencing more accessible and accelerate early clinical decisions for better health outcomes.

Strategic Imperatives

Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on Growth
The Strategic Imperative 8™
The Impact of the Top 3 Strategic Imperatives on the Advances in Next-Generation Sequencing and Genomic Analysis Industry
Growth Opportunities Fuel the Growth Pipeline Engine™
Research Methodology

Growth Opportunity Analysis

Scope of Analysis
Growth Drivers
Growth Drivers Analysis
Growth Restraints
Growth Restraints Analysis
Key Findings
Global Trends In Next-gen Sequencing and Genomic Analysis

Technology Innovations and R&D Scenario in Next-generation Sequencing and Genomic Analysis

The Evolution of Sequencing Methods
Key Focus Areas Leading to Improvements in Advanced Sequencing Technologies
The Growing Significance of NGS and its Capabilities
Technology Intervention Improving C
Evolution of NGS from Pyrosequencing to Advanced NGS
NGS Sequencing Chemistries and Their Adoption
Types of NGS Chemistries
Leading Industry Stakeholder Landscape and the NGS Platforms
Ongoing Sequencing Technology Developments of Market Leaders
Strategies that Improve Genomic Outcomes
Emerging Market Players Focus on Automation, AI integration and Improving Sequencing Chemistries
Approaches for Accurate and Fast Nucleic Acid Sequencing Using NGS
Trends in NGS Approaches and Genome Analysis
Advances in Robotics, Liquid handling and Library Preparation Advance NGS Automation Systems
Key Enablers Focusing on Automation for NGS
Role of AI in Driving Genomic Analysis
Key Players Focusing On AI, Bioinformatics Platforms For NGS Analysis
Industry Landscape of NGS Sequencing Providers and Integrated Services

Applications

Growing Adoption of NGS in Various Applications
NGS and Genomic Analysis Improving Mutational Analysis and Biomarker Discovery for Disease Diagnosis
Growing NGS Collaboration and Technology Platforms to Develop Rapid-NGS-based Diagnostic Tests
NGS And Genomic Analysis Improving Predictive Analysis for Precision Medicine
Key Players Focusing on NGS driven Precision Medicine
NGS And Genomic Analysis Improving
Growing NGS - Based Drug Discovery Companies
The Road Ahead for Next-generation Sequencing

R&D Collaborations

A Growing Network Acquisition to Improve NGS Capabilities
Global Public Funding and Consortium Efforts to Encourage Technology Knowledge and Collaboration

Growth Opportunity Universe

Growth Opportunity 1: Affordable Sequencing Services
Growth Opportunity 1: Affordable Sequencing Services
Growth Opportunity 2: Clinical Metagenomics for Low- and Middle-income Countries
Growth Opportunity 3: Platform Security and Regulations
Growth Opportunity 3: Platform Security and Regulations