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市場調查報告書
商品編碼
1886994
mRNA療法市場規模、佔有率、成長及全球產業分析:依類型、應用和地區劃分的洞察,以及2024年至2032年的預測mRNA Therapeutics Market Size, Share, Growth and Global Industry Analysis By Type & Application, Regional Insights and Forecast to 2024-2032 |
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全球mRNA療法市場正經歷快速發展,這得益於前所未有的科學進步、不斷擴展的生物技術以及在新冠疫情期間mRNA疫苗的成功商業化。根據最新的市場研究,在強勁的研發活動和mRNA疫苗日益普及的推動下,全球mRNA療法市場預計將在2024年達到89.1億美元。然而,隨著新冠疫苗需求的正常化和全球疫苗接種計畫的調整,預計到2025年,該市場規模將萎縮至60.1億美元。儘管目前市場暫時萎縮,但在創新、治療應用拓展和研發管線加速的推動下,預計到2032年,mRNA市場將快速增長至214.5億美元,2025年至2032年的複合年增長率將達到19.9%。
mRNA技術從根本上改變了製藥業的格局。曾經被視為實驗性平台的mRNA技術,如今已迅速發展成為傳染病、癌症、罕見遺傳疾病和個人化醫療領域的變革性技術。 mRNA新冠疫苗Comirnaty(輝瑞/BioNTech)和Spikebax(Moderna)的成功上市,充分展現了mRNA療法的潛力,並在全球市場樹立了良好的口碑。
北美地區在2024年以35.12%的市場佔有率(價值31.3億美元)引領全球市場,這得益於世界一流的研究基礎設施、充足的公共和私人資金,以及Moderna、輝瑞、BioNTech和葛蘭素史克等主要製藥創新企業的強大實力。
2025年的下滑反映了新冠疫苗接種活動的縮減。然而,從2026年開始,隨著各種研發管線接近商業化,預計市場將再次實現強勁的兩位數成長。
推動市場成長的因素
與小分子化合物、DNA疫苗和傳統生物製劑相比,mRNA療法具有若干獨特的優勢。
這些優勢正在加速針對流感、呼吸道合胞病毒(RSV)、痘病毒、寨卡病毒、瘧疾和愛滋病等傳染病的mRNA疫苗的研發。癌症疫苗和蛋白質替代療法領域也取得了進展。
雖然疫苗目前佔市場收入的主導地位,但mRNA療法正在拓展至以下領域:
預計從2027年起,製藥領域將成為成長最快的類別,首個mRNA藥物預計將於2027年上市,mRNA藥物市場預計將在2027年至2032年間以118.7%的複合年增長率增長,到2032年達到20億美元。
市場限制因子
mRNA分子需要超低溫才能維持穩定性。這阻礙了冷鏈基礎設施有限的地區,特別是低收入國家,採用mRNA技術。
mRNA的生產涉及以下流程:
這些因素需要大量的資本投入,並限制了全球產能。
mRNA藥物的監管框架仍在不斷發展中。儘管有強而有力的科學支持,但部分人士仍持懷疑態度,尤其是在新型疫苗技術方面。
主要市場趨勢
mRNA在藥物研發的應用日益廣泛
全球臨床試驗數量顯著成長,截至2022年,約40%的I期臨床試驗是基於mRNA技術。企業將mRNA應用於以下領域:
眾多合作、收購和協作表明,整個產業正在建立強大的研發管線。
遞送技術的突破性創新
脂質奈米顆粒 (LNP)、聚合物和陽離子奈米顆粒正在推動以下方面的改進:
這些創新降低了毒性,並擴大了治療應用範圍。
依類型
預防(疫苗)-預計 2024 年市佔率最大
預計 2024 年,疫苗細分市場將佔最大的市場佔有率,這主要得益於 COVID-19 疫苗和呼吸道合胞病毒 (RSV) 疫苗的批准。
已核准的產品包括:
正在研發的非新冠疫苗包括:
藥物/藥物 - 成長最快的領域
隨著 mRNA 療法的商業化,預計從 2027 年起將快速成長,尤其是在腫瘤領域。
依應用領域
傳染病領域 - 截至目前處於領先地位2024年
該領域佔領先地位,因為截至2025年初,所有核准的mRNA產品均針對傳染病。
腫瘤領域-高成長領域
多種癌症疫苗正在研發中,包括BioNTech公司用於治療非小細胞肺癌(NSCLC)的BNT116。
依分銷管道
北美 - 市場領導者(2024 年市場規模:31.3 億美元)
主要驅動因素
歐洲
德國和法國引領該地區,是 BioNTech、CureVac 和賽諾菲等主要公司的所在地。
亞太地區
這是成長最快的地區,主要受以下因素驅動:
其他
隨著拉丁美洲、中東和非洲醫療基礎設施的發展,這些地區對疫苗的興趣日益濃厚。
The global mRNA therapeutics market is undergoing a period of rapid evolution, driven by unprecedented scientific advancements, expanding biotechnology capabilities, and successful commercialization of mRNA-based vaccines during the COVID-19 pandemic. According to the latest market intelligence, the global mRNA therapeutics market size reached USD 8.91 billion in 2024, supported by robust R&D activities and rising acceptance of mRNA vaccines. However, the market is projected to decrease to USD 6.01 billion in 2025 due to normalization in COVID-19 vaccine demand and shifts in immunization programs worldwide. Despite this temporary contraction, the market is expected to surge to USD 21.45 billion by 2032, driven by innovation, expanding therapeutic applications, and accelerating pipeline development, achieving a CAGR of 19.9% between 2025 and 2032.
The mRNA field has fundamentally reshaped the pharmaceutical landscape. What was once considered an experimental platform has rapidly emerged as a transformational technology capable of addressing infectious diseases, cancer, rare genetic disorders, and personalized medicine. The successful deployment of mRNA COVID-19 vaccines-Comirnaty (Pfizer/BioNTech) and Spikevax (Moderna)-validated the potential of mRNA-based therapeutics and established strong global market confidence.
North America dominated the global market with a 35.12% share in 2024, valued at USD 3.13 billion, owing to its world-leading research infrastructure, substantial public and private funding, and strong presence of major pharmaceutical innovators such as Moderna, Pfizer, BioNTech, and GSK.
The decline in 2025 reflects reduced COVID-19 vaccination campaigns. However, post-2026, the market is anticipated to return to strong double-digit expansion as diverse pipelines move closer to commercialization.
Drivers Shaping Market Growth
mRNA therapies offer several unique advantages over small molecules, DNA vaccines, and conventional biologics:
These benefits are accelerating the development of mRNA vaccines for infectious diseases like influenza, RSV, Mpox, Zika, malaria, and HIV, as well as therapeutic vaccines for cancer and protein-replacement therapies.
Though vaccines dominate current market revenues, mRNA therapies are expanding into:
The drugs/medications segment is expected to become the fastest-growing category post-2027, supported by the anticipated launch of the first mRNA drug in 2027 and projections that the mRNA drug market will reach USD 2 billion by 2032 at a CAGR of 118.7% from 2027 to 2032.
Market Restraints
mRNA molecules require ultra-cold temperatures for stability. This continues to hinder adoption in regions with limited cold-chain infrastructure, particularly low-income countries.
mRNA production involves:
These factors contribute to high capital expenditures and limited global production capacity.
The regulatory framework for mRNA drugs is still evolving. Despite strong scientific backing, skepticism persists among certain segments of the population, particularly regarding new vaccine technologies.
Key Market Trends
Growing Adoption of mRNA in Drug Development
There has been substantial growth in clinical trials globally, with approximately 40% of mRNA-based clinical trials in Phase I as of 2022. Companies are using mRNA for:
Multiple partnerships, acquisitions, and collaborations indicate a strong pipeline across the industry.
Breakthrough Innovations in Delivery Technologies
LNPs, polymers, and cationic nanoparticles are improving:
These innovations reduce toxicity and allow broader therapeutic applications.
By Type
Prophylactic (Vaccines) - Dominant in 2024
The vaccines segment accounted for the highest share in 2024 due to COVID-19 and RSV vaccine approvals.
Approved products include:
Non-COVID vaccines in the pipeline include:
Drugs/Medications - Fastest Growing Segment
Expected boom after 2027 as mRNA therapeutics enter commercialization, especially in oncology.
By Application
Infectious Diseases - Leading in 2024
Because all approved mRNA products as of early 2025 target infectious diseases, this segment dominates.
Oncology - High Future Growth
Multiple cancer vaccines are in development, including BioNTech's BNT116 for NSCLC.
By Distribution Channel
North America - Market Leader (2024 Value: USD 3.13 Billion)
Key drivers:
Europe
Germany and France lead the region with major companies such as BioNTech, CureVac, and Sanofi.
Asia Pacific
Fastest-growing region, driven by:
Rest of the World
Latin America and Middle East & Africa show rising interest as healthcare infrastructure improves.
Competitive Landscape
Major players include:
These companies are investing heavily in:
Conclusion
The global mRNA therapeutics market is transforming rapidly, driven by technological innovation, expanded pipeline applications, rising funding, and growing acceptance of mRNA-based medicines. While the market dips from USD 8.91 billion in 2024 to USD 6.01 billion in 2025, it is set to rebound strongly, reaching USD 21.45 billion by 2032. With breakthroughs expected across oncology, infectious diseases, and rare genetic disorders, mRNA technology is positioned to become one of the most influential healthcare innovations of the 21st century.
Segmentation
By Type
By Application
By Distribution Channel
By Region