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市場調查報告書
商品編碼
1863974
連接酶市場按類型、形式、應用、來源、最終用戶和地區分類Ligase Enzymes Market, By Type, By Form, By Application, By Source, By End User, By Geography |
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2025年連接酶市場規模預計為2.678億美元，預計到2032年將達到4.385億美元，2025年至2032年的複合年成長率為7.3%。
| 分析範圍 | 分析詳情 | ||
|---|---|---|---|
| 基準年 | 2024 | 市場規模（2025 年） | 2.678億美元 |
| 效能數據 | 2020-2024 | 預測期 | 2025-2032 |
| 預測期（2025-2032 年）複合年成長率 | 7.30% | 預計金額（2032 年） | 4.385億美元 |
全球連接酶市場是生物技術和製藥行業的重要組成部分，涵蓋多種酶蛋白，它們透過形成共用鍵連接兩個分子。連接酶在酵素命名系統中被歸類為EC 6，在DNA複製、修復和重組等細胞過程中發揮基礎性作用，使其成為分子生物學研究、診斷和治療應用的重要工具。這些酵素利用從ATP和其他高能化合物獲得的能量來催化核酸、蛋白質和其他生物分子之間形成連接鍵。
市場涵蓋多種類型的連接酶，包括DNA連接酶、RNA連接酶和蛋白質連接酶，每種連接酶都在全球的研究機構、製藥公司和生物技術公司中用於特定的應用。隨著全球對精準醫療、基因治療和個人化醫療的日益關注，對高品質連接酶的需求持續激增，推動了酵素工程和生產流程的創新。此外，連接酶在CRISPR-Cas基因編輯技術、次世代定序平台和合成生物學計劃中的廣泛應用也支撐著市場的成長，使其成為推動現代生物技術發展的關鍵組成部分。
市場動態
全球連接酶市場的主要驅動力是基因組研究的指數級成長以及基因編輯技術在製藥和生物技術領域的日益普及。遺傳疾病和癌症的日益普及推動了對先進診斷和治療解決方案的需求，進而加速了分子克隆、PCR應用和DNA定序流程中對高性能連接酶的需求。此外，研發活動的大量投資，以及政府對基因組學舉措和個人化醫療計畫的資助，也顯著促進了市場擴張。
連接酶在合成生物學、疫苗研發和生物製藥生產中的應用日益廣泛，也推動了市場成長，因為這些酵素對於建構重組DNA分子和開發新型治療性蛋白質至關重要。然而，連接酶的應用也存在諸多局限性，包括酵素生產和純化成本高成本、酵素製劑產品監管要求嚴格，以及酵素穩定性及儲存條件的技術挑戰。
酵素生產的複雜性以及操作這些生物催化劑所需的專業知識，也對小型企業構成了市場進入障礙。儘管存在這些挑戰，但連接酶在液態生物檢體診斷、就地檢驗設備以及包括mRNA疫苗和基因治療載體在內的新一代治療方法等新興領域的應用不斷擴展，帶來了巨大的機遇，為市場參與企業提供了利用不斷發展的生物技術趨勢獲利的良機。
本報告的主要特點
- 本報告對全球連接酶市場進行了詳細分析，並以 2024 年為基準年，給出了預測期（2025-2032 年）的市場規模和復合年成長率。
- 它還重點介紹了各個細分市場的潛在商機，並描述了該市場中一系列有吸引力的投資提案。
- 它還提供了有關市場促進因素、限制因素和機會、新產品發布和核准、市場趨勢、區域展望以及主要企業採取的競爭策略的關鍵見解。
- 全球連接酶市場的主要企業概況、產品系列、主要亮點、財務表現和策略等參數均已列出。
- 本報告提供的見解將使負責人和企業經營團隊能夠就未來的產品發布、合作關係、市場擴張和行銷策略做出明智的決策。
- 《全球連接酶市場》報告涵蓋了該行業的各個相關人員，包括投資者、供應商、產品製造商、經銷商、新進入者和金融分析師。
- 相關人員可以透過用於分析全球連接酶市場的各種策略矩陣更輕鬆地做出決策。
目錄
第1章 分析目標和先決條件
- 分析目的
- 先決條件
- 簡稱
第2章 市場展望
- 報告說明
- 市場定義和範圍
- 執行摘要
第3章：市場動態、監管與趨勢分析
- 市場動態
- 促進要素
- 抑制因素
- 機會
- 影響分析
- 重大進展
- 監管情景
- 產品發布/核准
- PEST分析
- 波特五力分析
- 企業合併情景
- 產業趨勢
第4章 全球連結酶市場（按類型分類）（2020-2032 年）
- 介紹
- DNA連接酶
- RNA連接酶
- 其他連接酶（例如，胜肽連接酶、蛋白質連接酶）
5. 全球連結酶市場（按形式分類）（2020-2032 年）
- 介紹
- 液體配方
- 凍乾粉
6. 全球連結酶市場按應用領域分類（2020-2032 年）
- 介紹
- 研究與開發
- 克隆和誘變
- 次世代定序（NGS）文庫製備
- DNA合成與組裝（例如，吉布森組裝）
- SNP檢測和基因分型
- 其他研究
- 診斷
- 分子診斷檢測（例如，LAMP、PCR）
- 感染疾病檢測
- 識別其他遺傳疾病
- 治療藥物
- 藥物發現與開發
- 基因治療載體構建
- 其他（例如，質體構建）
7. 全球連結酶市場（依來源分類）（2020-2032 年）
- 介紹
- 微生物（細菌、病毒等）
- 動物
- 植物
8. 全球連結酶市場（按最終用戶分類）（2020-2032 年）
- 介紹
- 製藥和生物技術公司
- 醫院和診斷實驗室
- 合約研發生產組織（CRO/CMO）
- 學術研究機構
9. 全球連結酶市場（按地區分類）（2020-2032 年）
- 介紹
- 北美洲
- 美國
- 加拿大
- 拉丁美洲
- 巴西
- 阿根廷
- 墨西哥
- 其他拉丁美洲
- 歐洲
- 德國
- 英國
- 西班牙
- 法國
- 義大利
- 俄羅斯
- 其他歐洲
- 亞太地區
- 中國
- 印度
- 日本
- 澳洲
- 韓國
- ASEAN
- 亞太其他地區
- 中東
- 海灣合作理事會國家
- 以色列
- 其他中東地區
- 非洲
- 南非
- 北非
- 中非
第10章 競爭格局
- New England Biolabs
- Creative Enzymes.
- Thermo Fisher Scientific
- QIAGEN NV
- Promega Corporation
- Merck KGaA
- Takara Bio Inc.
- Agilent Technologies
- Bio-Rad Laboratories
- ArcticZymes Technologies
- Codexis, Inc.
- Lonza Group
- BioCat GmbH
- Lucigen Corporation
- Enzo Life Sciences
第11章 分析師建議
- 機會
- 分析師觀點
- Coherent Opportunity Map (COM)
第12章 參考文獻與分析方法
- 參考
- 分析方法
- 關於 Coherent Market Insights
Ligase Enzymes Market is estimated to be valued at USD 267.8 Mn in 2025 and is expected to reach USD 438.5 Mn by 2032, growing at a compound annual growth rate (CAGR) of 7.3% from 2025 to 2032.
| Report Coverage | Report Details | ||
|---|---|---|---|
| Base Year: | 2024 | Market Size in 2025: | USD 267.8 Mn |
| Historical Data for: | 2020 To 2024 | Forecast Period: | 2025 To 2032 |
| Forecast Period 2025 to 2032 CAGR: | 7.30% | 2032 Value Projection: | USD 438.5 Mn |
The global ligase enzymes market represents a critical segment within the biotechnology and pharmaceutical industries, encompassing a diverse array of enzymatic proteins that facilitate the joining of two molecules through the formation of covalent bonds. Ligase enzymes, classified as EC 6 in the enzyme nomenclature system, play fundamental roles in cellular processes including DNA replication, repair, and recombination, making them indispensable tools in molecular biology research, diagnostics, and therapeutic applications. These enzymes catalyze the formation of bonds between nucleic acids, proteins, and other biomolecules by utilizing energy from ATP or other high-energy compounds.
The market encompasses various types of ligases, including DNA ligases, RNA ligases, and protein ligases, each serving specific applications in research laboratories, pharmaceutical companies, and biotechnology firms worldwide. As the global focus on precision medicine, gene therapy, and personalized healthcare intensifies, the demand for high-quality ligase enzymes continues to surge, driving innovation in enzyme engineering and manufacturing processes. The market's growth trajectory is further supported by expanding applications in CRISPR-Cas gene editing technologies, next-generation sequencing platforms, and synthetic biology initiatives, positioning ligase enzymes as essential components in advancing modern biotechnological capabilities.
Market Dynamics
The global ligase enzymes market is primarily driven by the exponential growth in genomics research and the increasing adoption of gene editing technologies across pharmaceutical and biotechnology sectors. The rising prevalence of genetic disorders and cancer has intensified the demand for advanced diagnostic and therapeutic solutions, propelling the need for high-performance ligase enzymes in molecular cloning, PCR applications, and DNA sequencing procedures. Additionally, substantial investments in research and development activities, coupled with government funding for genomics initiatives and personalized medicine programs, are significantly boosting market expansion.
The growing applications of ligase enzymes in synthetic biology, vaccine development, and biopharmaceutical manufacturing further contribute to market growth, as these enzymes are essential for constructing recombinant DNA molecules and developing novel therapeutic proteins. However, the market faces notable restraints including the high cost of enzyme production and purification processes, stringent regulatory requirements for enzyme-based products, and technical challenges associated with enzyme stability and storage conditions.
The complexity of enzyme manufacturing and the need for specialized expertise in handling these biological catalysts also pose barriers to market entry for smaller players. Despite these challenges, significant opportunities emerge from the expanding applications of ligase enzymes in emerging fields such as liquid biopsy diagnostics, point-of-care testing devices, and next-generation therapeutic modalities including mRNA vaccines and gene therapy vectors, creating lucrative prospects for market participants to capitalize on evolving biotechnological trends.
Key Features of the Study
- This report provides in-depth analysis of the global ligase enzymes market, and provides market size (USD Million) and compound annual growth rate (CAGR%) for the forecast period (2025-2032), considering 2024 as the base year
- It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
- This study also provides key insights about market drivers, restraints, opportunities, new product launches or approvals, market trends, regional outlook, and competitive strategies adopted by key players
- It profiles key players in the global ligase enzymes market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies
- Key companies covered as a part of this study include New England Biolabs, Creative Enzymes., Thermo Fisher Scientific, QIAGEN N.V., Promega Corporation, Merck KGaA, Takara Bio Inc., Agilent Technologies, Bio-Rad Laboratories, ArcticZymes Technologies, Codexis, Inc., Lonza Group, BioCat GmbH, Lucigen Corporation, and Enzo Life Sciences
- Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
- The global ligase enzymes market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
- Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global ligase enzymes market
Market Segmentation
- Type Insights (Revenue, USD Mn, 2020 - 2032)
- DNA Ligases
- RNA Ligases
- Other Ligases (e.g., Peptide Ligases, Protein Ligases)
- Form Insights (Revenue, USD Mn, 2020 - 2032)
- Liquid Formulations
- Lyophilized Powders
- Application Insights (Revenue, USD Mn, 2020 - 2032)
- Research and Development
- Cloning and Mutagenesis
- Next-Generation Sequencing (NGS) Library Preparation
- DNA Synthesis and Assembly (e.g., Gibson Assembly)
- SNP Detection and Genotyping
- Other Research
- Diagnostics
- Molecular Diagnostic Assays (e.g., LAMP, PCR-based tests)
- Infectious Disease Detection
- Other Genetic Disorder Identification
- Therapeutics
- Drug Discovery and Development
- Gene Therapy Vector Construction
- Others (e.g., Plasmid Construction)
- Source Insights (Revenue, USD Mn, 2020 - 2032)
- Microorganisms (Bacteria, Virus, Others)
- Animal
- Plant
- End User Insights (Revenue, USD Mn, 2020 - 2032)
- Pharmaceutical and Biotechnology Companies
- Hospitals and Diagnostic Laboratories
- Contract Research and Manufacturing Organizations (CROs/CMOs)
- Academic and Research Institutes
- Regional Insights (Revenue, USD Mn, 2020 - 2032)
- North America
- U.S.
- Canada
- Latin America
- Brazil
- Argentina
- Mexico
- Rest of Latin America
- Europe
- Germany
- U.K.
- Spain
- France
- Italy
- Russia
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East
- GCC Countries
- Israel
- Rest of Middle East
- Africa
- South Africa
- North Africa
- Central Africa
- Key Players Insights
- New England Biolabs
- Creative Enzymes.
- Thermo Fisher Scientific
- QIAGEN N.V.
- Promega Corporation
- Merck KGaA
- Takara Bio Inc.
- Agilent Technologies
- Bio-Rad Laboratories
- ArcticZymes Technologies
- Codexis, Inc.
- Lonza Group
- BioCat GmbH
- Lucigen Corporation
- Enzo Life Sciences
Table of Contents
1. Research Objectives and Assumptions
- Research Objectives
- Assumptions
- Abbreviations
2. Market Purview
- Report Description
- Market Definition and Scope
- Executive Summary
- Global Ligase Enzymes Market, By Type
- Global Ligase Enzymes Market, By Form
- Global Ligase Enzymes Market, By Application
- Global Ligase Enzymes Market, By Source
- Global Ligase Enzymes Market, By End User
- Global Ligase Enzymes Market, By Region
3. Market Dynamics, Regulations, and Trends Analysis
- Market Dynamics
- Driver
- Restraint
- Opportunity
- Impact Analysis
- Key Developments
- Regulatory Scenario
- Product Launches/Approvals
- PEST Analysis
- PORTER's Analysis
- Merger and Acquisition Scenario
- Industry Trends
4. Global Ligase Enzymes Market, By Type, 2020-2032, (USD Mn)
- Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021 - 2032
- Segment Trends
- DNA Ligases
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- RNA Ligases
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Other Ligases (e.g., Peptide Ligases, Protein Ligases)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
5. Global Ligase Enzymes Market, By Form, 2020-2032, (USD Mn)
- Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021 - 2032
- Segment Trends
- Liquid Formulations
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Lyophilized Powders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
6. Global Ligase Enzymes Market, By Application, 2020-2032, (USD Mn)
- Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021 - 2032
- Segment Trends
- Research and Development
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Cloning and Mutagenesis
- Next-Generation Sequencing (NGS) Library Preparation
- DNA Synthesis and Assembly (e.g., Gibson Assembly)
- SNP Detection and Genotyping
- Other Research
- Diagnostics
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Molecular Diagnostic Assays (e.g., LAMP, PCR-based tests)
- Infectious Disease Detection
- Other Genetic Disorder Identification
- Therapeutics
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Drug Discovery and Development
- Gene Therapy Vector Construction
- Others (e.g., Plasmid Construction)
7. Global Ligase Enzymes Market, By Source, 2020-2032, (USD Mn)
- Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021 - 2032
- Segment Trends
- Microorganisms (Bacteria, Virus, Others)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Animal
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Plant
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
8. Global Ligase Enzymes Market, By End User, 2020-2032, (USD Mn)
- Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021 - 2032
- Segment Trends
- Pharmaceutical and Biotechnology Companies
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Hospitals and Diagnostic Laboratories
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Contract Research and Manufacturing Organizations (CROs/CMOs)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Academic and Research Institutes
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
9. Global Ligase Enzymes Market, By Region, 2020 - 2032, Value (USD Mn)
- Introduction
- Market Share (%) Analysis, 2025, 2028 & 2032, Value (USD Mn)
- Market Y-o-Y Growth Analysis (%), 2021 - 2032, Value (USD Mn)
- Regional Trends
- North America
- Introduction
- Market Size and Forecast, By Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Form, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Source, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- U.S.
- Canada
- Latin America
- Introduction
- Market Size and Forecast, By Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Form, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Source, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- Brazil
- Argentina
- Mexico
- Rest of Latin America
- Europe
- Introduction
- Market Size and Forecast, By Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Form, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Source, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- Germany
- U.K.
- Spain
- France
- Italy
- Russia
- Rest of Europe
- Asia Pacific
- Introduction
- Market Size and Forecast, By Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Form, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Source, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East
- Introduction
- Market Size and Forecast, By Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Form, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Source, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- GCC Countries
- Israel
- Rest of Middle East
- Africa
- Introduction
- Market Size and Forecast, By Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Form, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Source, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country/Region, 2020 - 2032, Value (USD Mn)
- South Africa
- North Africa
- Central Africa
10. Competitive Landscape
- New England Biolabs
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Creative Enzymes.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Thermo Fisher Scientific
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- QIAGEN N.V.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Promega Corporation
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Merck KGaA
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Takara Bio Inc.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Agilent Technologies
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Bio-Rad Laboratories
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- ArcticZymes Technologies
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Codexis, Inc.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Lonza Group
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- BioCat GmbH
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Lucigen Corporation
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
- Enzo Life Sciences
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
11. Analyst Recommendations
- Wheel of Fortune
- Analyst View
- Coherent Opportunity Map
12. References and Research Methodology
- References
- Research Methodology
- About Us
