Entresto 市場按適應症、劑型、強度、年齡層、性別、分銷管道、最終用戶和地區分類

2025 年創業市場規模估計為 90.9 億美元，預計到 2032 年將達到 122.1 億美元，2025 年至 2032 年的複合年成長率為 4.3%。

心臟衰竭盛行率不斷上升以及對創新治療方案日益成長的需求的推動，全球恩欣妥 (Entresto) 市場在心血管治療領域佔據關鍵地位。恩欣妥是一種突破性的血管收縮素受體-腦啡肽酶抑制劑 (ARNI)，它透過將沙庫巴曲和Valsartan結合在單一製劑中，心臟衰竭治療帶來了革命性的變化，與傳統的血管緊張素轉換酶 (ACE) 抑制劑相比，其臨床療效更為卓越。

這種雙機制藥物透過阻斷血管收縮素II 受體並同時抑制腦啡肽酶（一種分解有益利鈉肽的酶）來增強心血管保護並改善患者預後。人口老化、久坐不動的生活方式以及糖尿病和高血壓等併發症的日益增加（這些併發症會導致心臟衰竭）顯著推動了市場擴張。 Entresto 的臨床和經濟價值已得到全球醫療保健系統的認可，這從其被納入主要心臟衰竭治療指南以及在已開發市場和新興市場日益普及可以看出。

市場動態

全球 Entresto 市場受到多個強勁促進因素的支撐，這些因素凸顯了其強勁的成長軌跡和市場滲透潛力。第一個促進因素是全球心臟衰竭負擔日益加重，影響全球超過 6,400 萬人。人口老化和生活方式相關的心血管危險因子不斷擴大，需要先進治療性介入的患者群體也隨之擴大。臨床證據表明，與傳統療法相比，Entresto 在降低心血管死亡率和心臟衰竭住院率方面具有更顯著的療效，這正在加速醫生對 Entresto 的採用，並促使各大循環系統協會將其納入指南推薦。

醫療保健的經濟壓力和基於價值的護理計劃正在進一步推動市場成長，因為 Entresto 已透過降低住院率和改善生活品質證明了其成本效益。然而，市場擴張面臨重大限制因素，包括與學名藥相比價格較高，這給價格敏感型市場的可及性帶來了挑戰，並限制了其在預算受限的醫療保健系統中的採用。此外，某些禁忌症，如有血管性水腫病史的患者和更容易受到副作用影響的某些族裔患者，限制了目標患者群體。複雜的滴定要求和潛在的藥物交互作用也對醫療保健提供者的處方構成挑戰。儘管有這些限制，但新興市場地域分佈的不斷擴大、探索新適應症（包括射血分數保留的心臟衰竭）的臨床試驗正在進行中，以及可以顯著擴展治療用途和市場範圍的聯合治療的潛力，正在湧現出巨大的商機。

本報告的主要特點

• 本報告對全球創業市場進行了詳細分析，並以 2024 年為基準年，展示了預測期（2025-2032 年）的市場規模和複合年成長率。
• 它還強調了每個領域的潛在商機，並描述了該市場的一系列有吸引力的投資提案。
• 它還提供了有關市場促進因素、限制因素和機會、新產品發布和核准、市場趨勢、區域前景和主要企業採用的競爭策略的重要見解。
• 全球 Entresto 市場的主要企業已根據以下參數進行分析，例如公司概況、產品系列、主要亮點、財務表現和策略。
• 主要公司包括諾華公司。
• 本報告的見解將使負責人和企業經營團隊能夠就未來的產品發布、合作夥伴關係、市場擴張和行銷策略做出明智的決策。
• 「全球 Entresto 市場」報告涉及該行業的各個相關人員，包括投資者、供應商、產品製造商、經銷商、新進業者和金融分析師。
• 相關人員可以透過用於分析全球 Entresto 市場的各種策略矩陣更輕鬆地做出決策。

目錄

第1章 分析目標與前提條件

• 分析目的
• 先決條件
• 簡稱

第2章 市場展望

• 報告描述
  • 市場定義和範圍
• 執行摘要

第3章：市場動態、法規與趨勢分析

• 市場動態
• 驅動程式
• 抑制因素
• 機會
• 影響分析
• 主要進展
• 監管情景
• 產品發布/核准
• PEST分析
• 波特五力分析
• 企業合併（M&A）場景
• 產業趨勢

4.全球Entresto 市場以適應症分類（以金額為準，2020-2032 年）

• 慢性心臟衰竭（CHF）
• 兒科患者左心室收縮功能障礙伴隨症狀性心臟衰竭衰竭

5.全球Entresto 市場按劑型分類（以金額為準，2020-2032 年）

• 膜衣錠
• 膠囊中的薄膜衣口服顆粒

6.全球Entresto 市場以強度分類（以金額為準，2020-2032 年）

• 24/26mg
• 49/51mg
• 97/103 mg
• 6mg/6mg
• 15mg/16mg

7.全球Entresto 市場按年齡層別分類（以金額為準，2020-2032 年）

• 成人
• 孩子們

8.全球Entresto 市場以性別分類（以金額為準，2020-2032 年）

• 男性
• 女士

9.全球Entresto 市場按分銷管道分類（以金額為準，2020-2032 年）

• 醫院藥房
• 零售藥局
• 網路藥局

第 10 章：全球 Entresto 市場以最終用戶分類（以金額為準，2020-2032 年）

• 醫院和診所
• 心臟病中心
• 長期照護機構
• 門診治療中心
• 居家醫療
• 其他（學術研究機構等）

第 11 章 按地區分類的全球 Entresto 市場（以金額為準，2020-2032 年）

• 北美洲
  • 美國
  • 加拿大
• 拉丁美洲
  • 巴西
  • 阿根廷
  • 墨西哥
  • 其他拉丁美洲
• 歐洲
  • 德國
  • 英國
  • 西班牙
  • 法國
  • 義大利
  • 俄羅斯
  • 其他歐洲國家
• 亞太地區
  • 中國
  • 印度
  • 日本
  • 澳洲
  • 韓國
  • ASEAN
  • 其他亞太地區
• 中東
  • 海灣合作理事會國家
  • 以色列
  • 其他中東地區
• 非洲
  • 南非
  • 北非
  • 中部非洲

第12章競爭格局

• Novartis AG

第13章 分析師建議

• “命運之輪”
• 分析師觀點
• Coherent Opportunity Map (COM)

第14章參考文獻與調查方法

• 參考
• 分析方法
• 關於 Coherent Market Insights

ENTRESTO Market is estimated to be valued at USD 9.09 Bn in 2025 and is expected to reach USD 12.21 Bn by 2032, growing at a compound annual growth rate (CAGR) of 4.3% from 2025 to 2032.

The Global ENTRESTO Market represents a pivotal segment within the cardiovascular therapeutics landscape, driven by the increasing prevalence of heart failure and the growing demand for innovative treatment solutions. ENTRESTO, a groundbreaking angiotensin receptor-neprilysin inhibitor (ARNI), has revolutionized heart failure management by combining sacubitril and valsartan in a single formulation, offering superior clinical outcomes compared to traditional ACE inhibitors.

This dual-mechanism medication works by simultaneously blocking the angiotensin II receptor and inhibiting neprilysin, an enzyme responsible for breaking down beneficial natriuretic peptides, thereby providing enhanced cardiovascular protection and improved patient outcomes. The market's expansion is significantly influenced by the rising geriatric population, sedentary lifestyles, and increasing incidence of comorbidities such as diabetes and hypertension that contribute to heart failure development. Healthcare systems worldwide are increasingly recognizing the clinical and economic value of ENTRESTO, as evidenced by its inclusion in major heart failure treatment guidelines and growing adoption across both developed and emerging markets.

Market Dynamics

The Global ENTRESTO Market is propelled by several compelling drivers that underscore its robust growth trajectory and market penetration potential. The primary driver stems from the escalating global burden of heart failure, affecting over 64 million people worldwide, coupled with aging demographics and lifestyle-related cardiovascular risk factors that continue to expand the patient population requiring advanced therapeutic interventions. Clinical evidence demonstrating ENTRESTO's superior efficacy in reducing cardiovascular mortality and heart failure hospitalizations compared to traditional treatments has accelerated physician adoption and guideline recommendations across major cardiology societies.

Healthcare economic pressures and value-based care initiatives further drive market growth as ENTRESTO demonstrates cost-effectiveness through reduced hospitalization rates and improved quality of life metrics. However, market expansion faces significant restraints including the medication's premium pricing compared to generic alternatives, which creates accessibility challenges in price-sensitive markets and limits adoption in healthcare systems with stringent budget constraints. Additionally, specific contraindications, including patients with a history of angioedema and certain ethnic populations with higher susceptibility to adverse reactions, restrict the eligible patient population. Complex titration requirements and potential drug interactions also pose prescribing challenges for healthcare providers. Despite these constraints, substantial opportunities emerge from expanding geographical presence in emerging markets, ongoing clinical trials investigating new indications including preserved ejection fraction heart failure, and potential combination therapies that could broaden therapeutic applications and market reach significantly.

Key Features of the Study

• This report provides an in-depth analysis of the global ENTRESTO market, and provides market size (USD Billion) and compound annual growth rate (CAGR%) for the forecast period (2025-2032), considering 2024 as the base year.
• It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market.
• This study also provides key insights about market drivers, restraints, opportunities, new product launches or approvals, market trends, regional outlook, and competitive strategies adopted by key players.
• It profiles key players in the global ENTRESTO market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies.
• Key company covered as a part of this study include Novartis AG.
• Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics.
• The global ENTRESTO market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
• Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global ENTRESTO market.

Market Segmentation

• Indication Insights (Revenue, USD Bn, 2020 - 2032)
  • Chronic Heart Failure (CHF)
  • Symptomatic heart failure with left ventricular systolic dysfunction in pediatric patients
• Dosage Forms Insights (Revenue, USD Bn, 2020 - 2032)
  • Film-coated tablets
  • Film-coated oral pellets within capsules
• Strength Insights (Revenue, USD Bn, 2020 - 2032)
  • 24/26 mg
  • 49/51 mg
  • 97/103 mg
  • 6 mg/6 mg
  • 15 mg/16 mg
• Age Group Insights (Revenue, USD Bn, 2020 - 2032)
  • Adults
  • Pediatric
• Gender Insights (Revenue, USD Bn, 2020 - 2032)
  • Male
  • Female
• Distribution Channel Insights (Revenue, USD Bn, 2020 - 2032)
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
• End User Insights (Revenue, USD Bn, 2020 - 2032)
  • Hospitals and Clinics
  • Cardiology Centers
  • Long-Term Care Facilities
  • Ambulatory Care Centers
  • Homecare Settings
  • Others (Academic and Research Institutes, etc.)
• Regional Insights (Revenue, USD Bn, 2020 - 2032)
  • North America
  • U.S.
  • Canada
  • Latin America
  • Brazil
  • Argentina
  • Mexico
  • Rest of Latin America
  • Europe
  • Germany
  • U.K.
  • Spain
  • France
  • Italy
  • Russia
  • Rest of Europe
  • Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • ASEAN
  • Rest of Asia Pacific
  • Middle East
  • GCC Countries
  • Israel
  • Rest of Middle East
  • Africa
  • South Africa
  • North Africa
  • Central Africa
• Key Players Insights
  • Novartis AG

Table of Contents

1. Research Objectives and Assumptions

• Research Objectives
• Assumptions
• Abbreviations

2. Market Purview

• Report Description
  • Market Definition and Scope
• Executive Summary
  • Global ENTRESTO Market, By Indication
  • Global ENTRESTO Market, By Dosage Forms
  • Global ENTRESTO Market, By Strength
  • Global ENTRESTO Market, By Age Group
  • Global ENTRESTO Market, By Gender
  • Global ENTRESTO Market, By Distribution Channel
  • Global ENTRESTO Market, By End User
  • Global ENTRESTO Market, By Region

3. Market Dynamics, Regulations, and Trends Analysis

• Market Dynamics
• Driver
• Restraint
• Opportunity
• Impact Analysis
• Key Developments
• Regulatory Scenario
• Product Launches/Approvals
• PEST Analysis
• PORTER's Analysis
• Merger and Acquisition Scenario
• Industry Trends

4. Global ENTRESTO Market, By Indication, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Chronic Heart Failure (CHF)
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Symptomatic heart failure with left ventricular systolic dysfunction in pediatric patients
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

5. Global ENTRESTO Market, By Dosage Forms, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Film-coated tablets
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Film-coated oral pellets within capsules
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

6. Global ENTRESTO Market, By Strength, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• 24/26 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• 49/51 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• 97/103 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• 6 mg/6 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• 15 mg/16 mg
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

7. Global ENTRESTO Market, By Age Group, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Adults
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Pediatric
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

8. Global ENTRESTO Market, By Gender, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Male
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Female
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

9. Global ENTRESTO Market, By Distribution Channel, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Hospital Pharmacies
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Retail Pharmacies
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Online Pharmacies
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

10. Global ENTRESTO Market, By End User, 2020-2032, (USD Bn)

• Introduction
  • Market Share Analysis, 2025 and 2032 (%)
  • Y-o-Y Growth Analysis, 2021 - 2032
  • Segment Trends
• Hospitals and Clinics
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Cardiology Centers
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Long-Term Care Facilities
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Ambulatory Care Centers
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Homecare Settings
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)
• Others (Academic and Research Institutes, etc.)
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Bn)

11. Global ENTRESTO Market, By Region, 2020 - 2032, Value (USD Bn)

• Introduction
  • Market Share (%) Analysis, 2025, 2028 & 2032, Value (USD Bn)
  • Market Y-o-Y Growth Analysis (%), 2021 - 2032, Value (USD Bn)
  • Regional Trends
• North America
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • U.S.
    • Canada
• Latin America
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
• Europe
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • Germany
    • U.K.
    • Spain
    • France
    • Italy
    • Russia
    • Rest of Europe
• Asia Pacific
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • ASEAN
    • Rest of Asia Pacific
• Middle East
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country, 2020 - 2032, Value (USD Bn)
    • GCC Countries
    • Israel
    • Rest of Middle East
• Africa
  • Introduction
  • Market Size and Forecast, By Indication, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Dosage Forms, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Strength, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Age Group, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Gender, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Distribution Channel, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By End User, 2020 - 2032, Value (USD Bn)
  • Market Size and Forecast, By Country/Region, 2020 - 2032, Value (USD Bn)
    • South Africa
    • North Africa
    • Central Africa

12. Competitive Landscape

• Novartis AG
  • Company Highlights
  • Product Portfolio
  • Key Developments
  • Financial Performance
  • Strategies

13. Analyst Recommendations

• Wheel of Fortune
• Analyst View
• Coherent Opportunity Map

14. References and Research Methodology

• References
• Research Methodology
• About us